Multiple Long-Standing Papules and Nodules on the Left Lower Leg
A woman in her 60s with long-standing thickening and induration of the legs presented with 1 week of left leg pain. Physical examination results revealed multiple firm skin-colored papules and nodules coalescing to form a large plaque on the anterior aspect of the left lower leg, whereas the right lower leg had diffuse induration and hyperpigmentation. What is your diagnosis? (Source: JAMA Dermatology)
Source: JAMA Dermatology - August 23, 2023 Category: Dermatology Source Type: research
Safety and Efficacy of Tralokinumab in Older Adults With Moderate-to-Severe Atopic Dermatitis
This secondary analysis of 3 randomized clinical trial evaluates the safety and efficacy of tralokinumab in older patients with moderate-to-severe atopic dermatitis. (Source: JAMA Dermatology)
Source: JAMA Dermatology - August 23, 2023 Category: Dermatology Source Type: research
JAMA Network Call for Papers on Health and the 2024 US Election
Nationally and globally, health will continue to be one of the most important policy issues for the 2024 US election. Information about these health issues is critical for decision-making and to answer pressing public and global health questions affecting the US and the world. US elections are not only domestic; they affect world politics, economies, security, welfare, and health. (Source: JAMA Dermatology)
Source: JAMA Dermatology - August 18, 2023 Category: Dermatology Source Type: research
Prognostic Factors and Survival Outcomes Among Patients With Mycosis Fungoides in China
This retrospective cohort study of patients with mycosis fungoides evaluates prognostic factors and survival outcomes among a cohort in China during 12 years. (Source: JAMA Dermatology)
Source: JAMA Dermatology - August 16, 2023 Category: Dermatology Source Type: research
Treatment With Ataluren for Wound Healing and Health Complications in a Patient With Junctional Epidermolysis Bullosa
This case report describes an 11-year-old boy with widespread chronic wounds, frequent corneal erosions, dental caries, a tracheostomy, and failure to thrive. (Source: JAMA Dermatology)
Source: JAMA Dermatology - August 16, 2023 Category: Dermatology Source Type: research
Temporal Trends in the Use of Systemic Medications for Acne
This cross-sectional study uses data from the Truven MarketScan Commercial Claims Database for 2017 through 2020 to assess prescribing patterns for systemic acne treatments. (Source: JAMA Dermatology)
Source: JAMA Dermatology - August 16, 2023 Category: Dermatology Source Type: research
Prevalence and Tumors of CDKN2A -Related Melanoma-Astrocytoma Syndrome
This cohort study estimates the prevalence and describes tumor types of melanoma-astrocytoma syndrome. (Source: JAMA Dermatology)
Source: JAMA Dermatology - August 16, 2023 Category: Dermatology Source Type: research
Neuroimmune and Epithelial Dysregulation in Moderate to Severe Prurigo Nodularis
This cohort study analyzes the underlying changes in protein biomarkers and pathways in plasma samples associated with clinical improvement due to nemolizumab treatment among patients with prurigo nodularis. (Source: JAMA Dermatology)
Source: JAMA Dermatology - August 9, 2023 Category: Dermatology Source Type: research
Clinical Outcomes for Uptitration of Baricitinib Therapy in Patients With Severe Alopecia Areata
This pooled analysis aims to determine the efficacy of uptitration to baricitinib, 4 mg, for 24 weeks in patients who had previously not responded to baricitinib, 2 mg. (Source: JAMA Dermatology)
Source: JAMA Dermatology - August 9, 2023 Category: Dermatology Source Type: research
Association of Oral Corticosteroid Prescribing Pattern With Fracture Preventive Care in Older Adults
This cohort study conducted in the UK and Ontario, Canada, assesses the association between oral corticosteroid prescribing patterns and appropriate fracture preventive care among older adults with high cumulative oral corticosteroid exposure. (Source: JAMA Dermatology)
Source: JAMA Dermatology - August 9, 2023 Category: Dermatology Source Type: research
Gender Diversity of Mohs Micrographic Surgery Fellows and Program Directors in the US
This cross-sectional study examines trends in the percentage of females comprising Mohs micrographic surgery fellows and program directors for the past 2 decades in the US. (Source: JAMA Dermatology)
Source: JAMA Dermatology - August 9, 2023 Category: Dermatology Source Type: research
Can Serum Biomarkers for Prurigo Nodularis Expose Pathophysiology?
Prurigo nodularis (PN) is a chronic, pruritic skin disorder characterized by the development of hyperkeratotic nodules resulting in significant discomfort and reduced quality of life for affected individuals. While the pathophysiology of PN is not fully understood, both the immune and nervous systems have been implicated in the pathogenesis of the disease. Skin lesions in PN demonstrate increases in cutaneous nerve fiber density, immune cell infiltration, and cytokine expression in addition to the obvious epidermal hyperplasia and hyperkeratosis. Specifically, elevations in cytokine levels such as interleukin 4 (IL-4), IL-...
Source: JAMA Dermatology - August 9, 2023 Category: Dermatology Source Type: research
A Reddish Semitransparent Tumor in an Adolescent Girl
A previously healthy 16-year-old girl presented with a lesion on her right upper arm that initially started as a small cutaneous nodule without obvious triggers and gradually developed and enlarged to form a red-colored tumor with a hard nodule inside. What is your diagnosis? (Source: JAMA Dermatology)
Source: JAMA Dermatology - August 9, 2023 Category: Dermatology Source Type: research
Evaluation of Dupilumab in Patients With Bullous Pemphigoid
This retrospective cohort study assesses the patient outcomes and safety of dupilumab in adults with bullous pemphigoid. (Source: JAMA Dermatology)
Source: JAMA Dermatology - August 2, 2023 Category: Dermatology Source Type: research
Systematic Identification of Copositivity Groups in Standard Series Patch Testing Through Hierarchical Clustering
This retrospective analysis uses patient data to systematically determine allergen copositivity groups in the Mayo Clinic Standard Series to provide guidance on contact avoidance protocols. (Source: JAMA Dermatology)
Source: JAMA Dermatology - August 2, 2023 Category: Dermatology Source Type: research
