Human Leukocyte Antigens and Sulfamethoxazole/Cotrimoxazole –Induced Severe Cutaneous Adverse Reactions
This systematic review and meta-analysis examines the association between human leukocyte antigen genotypes and sulfamethoxazole/cotrimoxazole –induced severe cutaneous adverse reactions. (Source: JAMA Dermatology)
Source: JAMA Dermatology - April 3, 2024 Category: Dermatology Source Type: research

Long-Term Antibiotic Prescriptions for Acne Treatment
This qualitative study assesses antibiotic prescribing practices for acne to identify challenges to antibiotic stewardship among dermatologists. (Source: JAMA Dermatology)
Source: JAMA Dermatology - April 3, 2024 Category: Dermatology Source Type: research

Tofacitinib Treatment for Pretibial Myxedema
This case report describes tofacitinib treatment for 2 patients with pretibial myxedema. (Source: JAMA Dermatology)
Source: JAMA Dermatology - April 3, 2024 Category: Dermatology Source Type: research

Cutaneous Stigmata of Bacterial Endocarditis
This case report describes Osler nodes and Janeway lesions on a man in his 70s. (Source: JAMA Dermatology)
Source: JAMA Dermatology - April 3, 2024 Category: Dermatology Source Type: research

Precision in Language Regarding Geographic Region of Origin in Severe Cutaneous Adverse Drug Reaction Research
In this study, the authors reported a subgroup analysis of severe cutaneous adverse reactions by geographic region of origin inclusive of Japanese, Malaysian, Taiwanese, Thai, and European individuals. The level of granularity in analysis and reporting conducted by Wu et al on the geographic region of origin of patients is an important reminder of the genetic and clinical variation that can exist within populations that are often racialized into large heterogeneous groups. (Source: JAMA Dermatology)
Source: JAMA Dermatology - April 3, 2024 Category: Dermatology Source Type: research

Red Nodule on the Scalp in a Healthy Young Man
A man in his 40s was referred for an 8-mm red, firm, mobile nodule with irregular red lacunae and vessels and an absence of septa. What is your diagnosis? (Source: JAMA Dermatology)
Source: JAMA Dermatology - April 3, 2024 Category: Dermatology Source Type: research

JAMA Dermatology
Mission Statement:  JAMA Dermatology’s mission is to elevate the art and science of health and diseases of skin, hair, nails, and mucous membranes, and their treatment, to enable dermatologists to deliver evidence-based, high-value medical and surgical dermatologic care. The journal publishes a broad range of inn ovative studies and trials that shift research and clinical practice paradigms, expand the understanding of the burden of dermatologic diseases and key outcomes, improve the practice of dermatology, and ensure equitable care to all patients. The journal also features research and opinion examining e thical, m...
Source: JAMA Dermatology - April 1, 2024 Category: Dermatology Source Type: research

Cutaneous Lesions in Darier Disease and Somatic ATP2A2 Variants
This case series examines the molecular mechanisms underlying the development of persistent skin lesions in Darier disease. (Source: JAMA Dermatology)
Source: JAMA Dermatology - March 27, 2024 Category: Dermatology Source Type: research

Thermal Imaging and ALT-70 Prediction Model to Differentiate Cellulitis From Pseudocellulitis
This diagnostic study validates differences in skin surface temperatures between patients with cellulitis and patients with pseudocellulitis, assesses the optimal temperature measure and cut point for differentiating cellulitis from pseudocellulitis, and compares the performance of skin surface temperature and the ALT-70 score. (Source: JAMA Dermatology)
Source: JAMA Dermatology - March 27, 2024 Category: Dermatology Source Type: research

RRD With Bruton Tyrosine Kinase Inhibitor Therapy
This case report describes a woman in her 70s with a history of breast cancer and chronic lymphocytic leukemia who presented with a painful rash of the bilateral chest extending onto the flanks. (Source: JAMA Dermatology)
Source: JAMA Dermatology - March 27, 2024 Category: Dermatology Source Type: research

Hyperhidrosis and Hypermobility Spectrum Disorders Among Adolescents
This cross-sectional study assesses the prevalence and risk of excessive sweating and joint hypermobility in Israeli adolescents aged 16 to 19 years. (Source: JAMA Dermatology)
Source: JAMA Dermatology - March 27, 2024 Category: Dermatology Source Type: research

Quest for a More Accurate Diagnosis of Cellulitis
For most physicians, cellulitis is one of the classic “I know it when I see it” diseases, in which a diagnosis is rendered, antibiotics initiated, and the patient is quickly out of sight and out of mind. Unfortunately, being common and being simple are not the same, and more than one-third of patients suspected to have cellulitis are incorrectly di agnosed. The cumulative burden of misdiagnosis results in unnecessary antibiotic use, hospitalizations, and tremendous health care expenditures. (Source: JAMA Dermatology)
Source: JAMA Dermatology - March 27, 2024 Category: Dermatology Source Type: research

Outcome Measurement Instruments for Dermatologic Adverse Events in Cancer Trials
This systematic review evaluates heterogeneity and quality of clinician-reported and patient-reported outcome measures for assessing dermatologic adverse events related to systemic cancer treatment. (Source: JAMA Dermatology)
Source: JAMA Dermatology - March 20, 2024 Category: Dermatology Source Type: research

JAMA Dermatology Peer Reviewers in 2023
We sincerely thank the 657 peer reviewers who completed manuscript reviews for JAMA Dermatology in 2023. (Source: JAMA Dermatology)
Source: JAMA Dermatology - March 20, 2024 Category: Dermatology Source Type: research

Considerations Regarding Mohs Surgery for Early-Stage Merkel Cell Carcinoma —Reply
In Reply We appreciate the interest in our article by Faries and Venna et al as well as their comments on the analysis. While we agree that there are inherent limitations to retrospective studies of survival outcomes using registry data, we believe that it is prudent to glean what insights we can from these datasets given the lack of large-scale studies of rare cancers, such as Merkel cell carcinoma (MCC), in the existing literature. (Source: JAMA Dermatology)
Source: JAMA Dermatology - March 20, 2024 Category: Dermatology Source Type: research