Gut Microbiome in Patients With Early-Stage and Late-Stage Melanoma
This case-control study compares differences in the fecal microbiota —including overall diversity, composition, and putative function—between control participants and patients with melanoma and between patients with early and late-stage melanoma. (Source: JAMA Dermatology)
Source: JAMA Dermatology - August 30, 2023 Category: Dermatology Source Type: research

Risk of Inflammatory Bowel Disease in Atopic Dermatitis
This cohort study examines the association between atopic dermatitis and inflammatory bowel disease in children and adults. (Source: JAMA Dermatology)
Source: JAMA Dermatology - August 30, 2023 Category: Dermatology Source Type: research

Elevated Risk of Visceral Malignant Neoplasm in EMPD
This cross-sectional study evaluates the incidence and types of cancers that develop years after an extramammary Paget disease (EMPD) diagnosis. (Source: JAMA Dermatology)
Source: JAMA Dermatology - August 30, 2023 Category: Dermatology Source Type: research

Foscarnet-Induced Penile Ulceration
This case report describes an uncircumcised male individual with tender perimeatal erythema and ulceration extending to the right glans. (Source: JAMA Dermatology)
Source: JAMA Dermatology - August 30, 2023 Category: Dermatology Source Type: research

The Gut Microbiome in Melanoma
The gut contains approximately  100 trillion commensal microorganisms, including viruses, archaea, bacteria, and unicellular eukaryotes that influence the development and function of the human neurological, immunological, and digestive systems from birth through adulthood. These collective microbes and their genes comprise the gut microbiome, which has gained clinical interest in many specialties as a diagnostic and potential therapeutic tool for several diseases and malignant neoplasms. The bacterial component of the gut microbiome is the most well-characterized and can be studied in a culture-independent manner using 1...
Source: JAMA Dermatology - August 30, 2023 Category: Dermatology Source Type: research

Mental Health and Psychosocial Quality-of-Life Burden Among Patients With Vitiligo
This qualitative study investigates the mental health and psychosocial quality-of-life burden worldwide among patients with vitiligo. (Source: JAMA Dermatology)
Source: JAMA Dermatology - August 30, 2023 Category: Dermatology Source Type: research

Overall Survival After Mohs Surgery for Early-Stage Merkel Cell Carcinoma
This cohort study of adults with Merkel cell carcinoma evaluates the association of Mohs micrographic surgery vs wide local excision with overall survival. (Source: JAMA Dermatology)
Source: JAMA Dermatology - August 23, 2023 Category: Dermatology Source Type: research

Diffuse Cutaneous Aphthosis After Combined Targeted Therapies and Responsive to Pentoxifylline
This case series describes 3 patients who developed cutaneous aphthosis while taking an epidermal growth factor receptor inhibitor in combination with an MEK inhibitor. (Source: JAMA Dermatology)
Source: JAMA Dermatology - August 23, 2023 Category: Dermatology Source Type: research

Multiple Long-Standing Papules and Nodules on the Left Lower Leg
A woman in her 60s with long-standing thickening and induration of the legs presented with 1 week of left leg pain. Physical examination results revealed multiple firm skin-colored papules and nodules coalescing to form a large plaque on the anterior aspect of the left lower leg, whereas the right lower leg had diffuse induration and hyperpigmentation. What is your diagnosis? (Source: JAMA Dermatology)
Source: JAMA Dermatology - August 23, 2023 Category: Dermatology Source Type: research

Safety and Efficacy of Tralokinumab in Older Adults With Moderate-to-Severe Atopic Dermatitis
This secondary analysis of 3 randomized clinical trial evaluates the safety and efficacy of tralokinumab in older patients with moderate-to-severe atopic dermatitis. (Source: JAMA Dermatology)
Source: JAMA Dermatology - August 23, 2023 Category: Dermatology Source Type: research

JAMA Network Call for Papers on Health and the 2024 US Election
Nationally and globally, health will continue to be one of the most important policy issues for the 2024 US election. Information about these health issues is critical for decision-making and to answer pressing public and global health questions affecting the US and the world. US elections are not only domestic; they affect world politics, economies, security, welfare, and health. (Source: JAMA Dermatology)
Source: JAMA Dermatology - August 18, 2023 Category: Dermatology Source Type: research

Prognostic Factors and Survival Outcomes Among Patients With Mycosis Fungoides in China
This retrospective cohort study of patients with mycosis fungoides evaluates prognostic factors and survival outcomes among a cohort in China during 12 years. (Source: JAMA Dermatology)
Source: JAMA Dermatology - August 16, 2023 Category: Dermatology Source Type: research

Treatment With Ataluren for Wound Healing and Health Complications in a Patient With Junctional Epidermolysis Bullosa
This case report describes an 11-year-old boy with widespread chronic wounds, frequent corneal erosions, dental caries, a tracheostomy, and failure to thrive. (Source: JAMA Dermatology)
Source: JAMA Dermatology - August 16, 2023 Category: Dermatology Source Type: research

Temporal Trends in the Use of Systemic Medications for Acne
This cross-sectional study uses data from the Truven MarketScan Commercial Claims Database for 2017 through 2020 to assess prescribing patterns for systemic acne treatments. (Source: JAMA Dermatology)
Source: JAMA Dermatology - August 16, 2023 Category: Dermatology Source Type: research

Prevalence and Tumors of CDKN2A -Related Melanoma-Astrocytoma Syndrome
This cohort study estimates the prevalence and describes tumor types of melanoma-astrocytoma syndrome. (Source: JAMA Dermatology)
Source: JAMA Dermatology - August 16, 2023 Category: Dermatology Source Type: research