Potential Role of Tranexamic Acid and Nonablative Fractional Resurfacing in Managing Facial Hyperpigmentation —Reply

In Reply We thank Hashemi et al for their engagement and thoughtful reply to our article that highlighted their experience with tranexamic acid (TA) and procedural therapies. We agree that treatment approaches in hyperpigmentation have had great advancements. We also recognize that tranexamic acid offers an additional option for treating melasma, as we discussed in our article. However, more guidance is needed on optimal therapeutic ranges, dosing regimens, length of treatment, and effects on certain patient populations, such as those receiving hormonal treatments and/or with hypercoagulable disorders. While TA has a prominent role in the treatment paradigm of melasma, it is not without risks and should be used and offered with proper medical judgment.

Source: JAMA Dermatology - February 1, 2024 Category: Dermatology Source Type: research