Natural mineral fibers: conducting inhalation toxicology studies - part A: Libby Amphibole aerosol generation and characterization method development
CONCLUSIONS: Characterization of the prototype system demonstrated feasibility of generating LA 2007 fiber aerosols appropriate for in vivo inhalation toxicity studies. The methods developed in this study are suitable to apply to a multiple-carousel exposure system for a rat inhalation toxicity testing using LA 2007.PMID:37339371 | DOI:10.1080/08958378.2023.2220737 (Source: Inhalation Toxicology)
Source: Inhalation Toxicology - June 20, 2023 Category: Respiratory Medicine Authors: Anbo Wang Amit Gupta Michael D Grimm David T Pressburger Barney R Sparrow Jamie S Richey John R Shaw Karen E Elsass Georgia K Roberts Pei-Li Yao Matthew D Stout Benjamin J Ellis Robyn L Ray Source Type: research

Natural mineral fibers: conducting inhalation toxicology studies-part B: development of a nose-only exposure system for repeat-exposure < em > in  vivo < /em > study of Libby amphibole aerosol
CONCLUSION: The exposure system developed is ready for use in conducting nose-only inhalation toxicity studies of LA 2007 in rats. The exposure system is anticipated to have applicability for the inhalation toxicity evaluation of other natural mineral fibers of concern.PMID:37339372 | DOI:10.1080/08958378.2023.2220735 (Source: Inhalation Toxicology)
Source: Inhalation Toxicology - June 20, 2023 Category: Respiratory Medicine Authors: Anbo Wang Amit Gupta Michael D Grimm David T Pressburger Barney R Sparrow Jamie S Richey John R Shaw Karen E Elsass Georgia K Roberts Pei-Li Yao Matthew D Stout Benjamin J Ellis Robyn L Ray Source Type: research

Natural mineral fibers: conducting inhalation toxicology studies - part A: Libby Amphibole aerosol generation and characterization method development
CONCLUSIONS: Characterization of the prototype system demonstrated feasibility of generating LA 2007 fiber aerosols appropriate for in vivo inhalation toxicity studies. The methods developed in this study are suitable to apply to a multiple-carousel exposure system for a rat inhalation toxicity testing using LA 2007.PMID:37339371 | DOI:10.1080/08958378.2023.2220737 (Source: Inhalation Toxicology)
Source: Inhalation Toxicology - June 20, 2023 Category: Respiratory Medicine Authors: Anbo Wang Amit Gupta Michael D Grimm David T Pressburger Barney R Sparrow Jamie S Richey John R Shaw Karen E Elsass Georgia K Roberts Pei-Li Yao Matthew D Stout Benjamin J Ellis Robyn L Ray Source Type: research

Natural mineral fibers: conducting inhalation toxicology studies-part B: development of a nose-only exposure system for repeat-exposure < em > in  vivo < /em > study of Libby amphibole aerosol
CONCLUSION: The exposure system developed is ready for use in conducting nose-only inhalation toxicity studies of LA 2007 in rats. The exposure system is anticipated to have applicability for the inhalation toxicity evaluation of other natural mineral fibers of concern.PMID:37339372 | DOI:10.1080/08958378.2023.2220735 (Source: Inhalation Toxicology)
Source: Inhalation Toxicology - June 20, 2023 Category: Respiratory Medicine Authors: Anbo Wang Amit Gupta Michael D Grimm David T Pressburger Barney R Sparrow Jamie S Richey John R Shaw Karen E Elsass Georgia K Roberts Pei-Li Yao Matthew D Stout Benjamin J Ellis Robyn L Ray Source Type: research

Natural mineral fibers: conducting inhalation toxicology studies - part A: Libby Amphibole aerosol generation and characterization method development
CONCLUSIONS: Characterization of the prototype system demonstrated feasibility of generating LA 2007 fiber aerosols appropriate for in vivo inhalation toxicity studies. The methods developed in this study are suitable to apply to a multiple-carousel exposure system for a rat inhalation toxicity testing using LA 2007.PMID:37339371 | DOI:10.1080/08958378.2023.2220737 (Source: Inhalation Toxicology)
Source: Inhalation Toxicology - June 20, 2023 Category: Respiratory Medicine Authors: Anbo Wang Amit Gupta Michael D Grimm David T Pressburger Barney R Sparrow Jamie S Richey John R Shaw Karen E Elsass Georgia K Roberts Pei-Li Yao Matthew D Stout Benjamin J Ellis Robyn L Ray Source Type: research

Natural mineral fibers: conducting inhalation toxicology studies-part B: development of a nose-only exposure system for repeat-exposure < em > in  vivo < /em > study of Libby amphibole aerosol
CONCLUSION: The exposure system developed is ready for use in conducting nose-only inhalation toxicity studies of LA 2007 in rats. The exposure system is anticipated to have applicability for the inhalation toxicity evaluation of other natural mineral fibers of concern.PMID:37339372 | DOI:10.1080/08958378.2023.2220735 (Source: Inhalation Toxicology)
Source: Inhalation Toxicology - June 20, 2023 Category: Respiratory Medicine Authors: Anbo Wang Amit Gupta Michael D Grimm David T Pressburger Barney R Sparrow Jamie S Richey John R Shaw Karen E Elsass Georgia K Roberts Pei-Li Yao Matthew D Stout Benjamin J Ellis Robyn L Ray Source Type: research

Natural mineral fibers: conducting inhalation toxicology studies - part A: Libby Amphibole aerosol generation and characterization method development
CONCLUSIONS: Characterization of the prototype system demonstrated feasibility of generating LA 2007 fiber aerosols appropriate for in vivo inhalation toxicity studies. The methods developed in this study are suitable to apply to a multiple-carousel exposure system for a rat inhalation toxicity testing using LA 2007.PMID:37339371 | DOI:10.1080/08958378.2023.2220737 (Source: Inhalation Toxicology)
Source: Inhalation Toxicology - June 20, 2023 Category: Respiratory Medicine Authors: Anbo Wang Amit Gupta Michael D Grimm David T Pressburger Barney R Sparrow Jamie S Richey John R Shaw Karen E Elsass Georgia K Roberts Pei-Li Yao Matthew D Stout Benjamin J Ellis Robyn L Ray Source Type: research

Natural mineral fibers: conducting inhalation toxicology studies-part B: development of a nose-only exposure system for repeat-exposure < em > in  vivo < /em > study of Libby amphibole aerosol
CONCLUSION: The exposure system developed is ready for use in conducting nose-only inhalation toxicity studies of LA 2007 in rats. The exposure system is anticipated to have applicability for the inhalation toxicity evaluation of other natural mineral fibers of concern.PMID:37339372 | DOI:10.1080/08958378.2023.2220735 (Source: Inhalation Toxicology)
Source: Inhalation Toxicology - June 20, 2023 Category: Respiratory Medicine Authors: Anbo Wang Amit Gupta Michael D Grimm David T Pressburger Barney R Sparrow Jamie S Richey John R Shaw Karen E Elsass Georgia K Roberts Pei-Li Yao Matthew D Stout Benjamin J Ellis Robyn L Ray Source Type: research

Natural mineral fibers: conducting inhalation toxicology studies - part A: Libby Amphibole aerosol generation and characterization method development
CONCLUSIONS: Characterization of the prototype system demonstrated feasibility of generating LA 2007 fiber aerosols appropriate for in vivo inhalation toxicity studies. The methods developed in this study are suitable to apply to a multiple-carousel exposure system for a rat inhalation toxicity testing using LA 2007.PMID:37339371 | DOI:10.1080/08958378.2023.2220737 (Source: Inhalation Toxicology)
Source: Inhalation Toxicology - June 20, 2023 Category: Respiratory Medicine Authors: Anbo Wang Amit Gupta Michael D Grimm David T Pressburger Barney R Sparrow Jamie S Richey John R Shaw Karen E Elsass Georgia K Roberts Pei-Li Yao Matthew D Stout Benjamin J Ellis Robyn L Ray Source Type: research

Natural mineral fibers: conducting inhalation toxicology studies-part B: development of a nose-only exposure system for repeat-exposure < em > in  vivo < /em > study of Libby amphibole aerosol
CONCLUSION: The exposure system developed is ready for use in conducting nose-only inhalation toxicity studies of LA 2007 in rats. The exposure system is anticipated to have applicability for the inhalation toxicity evaluation of other natural mineral fibers of concern.PMID:37339372 | DOI:10.1080/08958378.2023.2220735 (Source: Inhalation Toxicology)
Source: Inhalation Toxicology - June 20, 2023 Category: Respiratory Medicine Authors: Anbo Wang Amit Gupta Michael D Grimm David T Pressburger Barney R Sparrow Jamie S Richey John R Shaw Karen E Elsass Georgia K Roberts Pei-Li Yao Matthew D Stout Benjamin J Ellis Robyn L Ray Source Type: research

Natural mineral fibers: conducting inhalation toxicology studies - part A: Libby Amphibole aerosol generation and characterization method development
CONCLUSIONS: Characterization of the prototype system demonstrated feasibility of generating LA 2007 fiber aerosols appropriate for in vivo inhalation toxicity studies. The methods developed in this study are suitable to apply to a multiple-carousel exposure system for a rat inhalation toxicity testing using LA 2007.PMID:37339371 | DOI:10.1080/08958378.2023.2220737 (Source: Inhalation Toxicology)
Source: Inhalation Toxicology - June 20, 2023 Category: Respiratory Medicine Authors: Anbo Wang Amit Gupta Michael D Grimm David T Pressburger Barney R Sparrow Jamie S Richey John R Shaw Karen E Elsass Georgia K Roberts Pei-Li Yao Matthew D Stout Benjamin J Ellis Robyn L Ray Source Type: research

Natural mineral fibers: conducting inhalation toxicology studies-part B: development of a nose-only exposure system for repeat-exposure < em > in  vivo < /em > study of Libby amphibole aerosol
CONCLUSION: The exposure system developed is ready for use in conducting nose-only inhalation toxicity studies of LA 2007 in rats. The exposure system is anticipated to have applicability for the inhalation toxicity evaluation of other natural mineral fibers of concern.PMID:37339372 | DOI:10.1080/08958378.2023.2220735 (Source: Inhalation Toxicology)
Source: Inhalation Toxicology - June 20, 2023 Category: Respiratory Medicine Authors: Anbo Wang Amit Gupta Michael D Grimm David T Pressburger Barney R Sparrow Jamie S Richey John R Shaw Karen E Elsass Georgia K Roberts Pei-Li Yao Matthew D Stout Benjamin J Ellis Robyn L Ray Source Type: research

Natural mineral fibers: conducting inhalation toxicology studies - part A: Libby Amphibole aerosol generation and characterization method development
CONCLUSIONS: Characterization of the prototype system demonstrated feasibility of generating LA 2007 fiber aerosols appropriate for in vivo inhalation toxicity studies. The methods developed in this study are suitable to apply to a multiple-carousel exposure system for a rat inhalation toxicity testing using LA 2007.PMID:37339371 | DOI:10.1080/08958378.2023.2220737 (Source: Inhalation Toxicology)
Source: Inhalation Toxicology - June 20, 2023 Category: Respiratory Medicine Authors: Anbo Wang Amit Gupta Michael D Grimm David T Pressburger Barney R Sparrow Jamie S Richey John R Shaw Karen E Elsass Georgia K Roberts Pei-Li Yao Matthew D Stout Benjamin J Ellis Robyn L Ray Source Type: research

Natural mineral fibers: conducting inhalation toxicology studies-part B: development of a nose-only exposure system for repeat-exposure < em > in  vivo < /em > study of Libby amphibole aerosol
CONCLUSION: The exposure system developed is ready for use in conducting nose-only inhalation toxicity studies of LA 2007 in rats. The exposure system is anticipated to have applicability for the inhalation toxicity evaluation of other natural mineral fibers of concern.PMID:37339372 | DOI:10.1080/08958378.2023.2220735 (Source: Inhalation Toxicology)
Source: Inhalation Toxicology - June 20, 2023 Category: Respiratory Medicine Authors: Anbo Wang Amit Gupta Michael D Grimm David T Pressburger Barney R Sparrow Jamie S Richey John R Shaw Karen E Elsass Georgia K Roberts Pei-Li Yao Matthew D Stout Benjamin J Ellis Robyn L Ray Source Type: research

Natural mineral fibers: conducting inhalation toxicology studies - part A: Libby Amphibole aerosol generation and characterization method development
CONCLUSIONS: Characterization of the prototype system demonstrated feasibility of generating LA 2007 fiber aerosols appropriate for in vivo inhalation toxicity studies. The methods developed in this study are suitable to apply to a multiple-carousel exposure system for a rat inhalation toxicity testing using LA 2007.PMID:37339371 | DOI:10.1080/08958378.2023.2220737 (Source: Inhalation Toxicology)
Source: Inhalation Toxicology - June 20, 2023 Category: Respiratory Medicine Authors: Anbo Wang Amit Gupta Michael D Grimm David T Pressburger Barney R Sparrow Jamie S Richey John R Shaw Karen E Elsass Georgia K Roberts Pei-Li Yao Matthew D Stout Benjamin J Ellis Robyn L Ray Source Type: research