Evaluation of neural reflex activation as a potential mode of action for respiratory and cardiovascular effects of fine particulate matter
CONCLUSIONS: Further studies are needed to determine whether neural reflex activation is the MoA by which PM2.5 could cause either respiratory or cardiovascular morbidities in humans, particularly at the ambient concentrations associated with total mortality in epidemiology studies.PMID:38488087 | DOI:10.1080/08958378.2024.2324033 (Source: Inhalation Toxicology)
Source: Inhalation Toxicology - March 15, 2024 Category: Respiratory Medicine Authors: Robyn L Prueitt Cassandra J Meakin Nicholas L Drury Julie E Goodman Source Type: research

Crystalline silica-induced pulmonary inflammation and autoimmunity in mature adult NZBW/f1 mice: age-related sensitivity and impact of omega-3 fatty acid intervention
CONCLUSION: These results highlight life-stage significance in this preclinical lupus model and underscore omega-3 fatty acids' therapeutic potential against toxicant-triggered autoimmune responses.PMID:38477125 | DOI:10.1080/08958378.2024.2318378 (Source: Inhalation Toxicology)
Source: Inhalation Toxicology - March 13, 2024 Category: Respiratory Medicine Authors: Lauren K Heine Tasha Scarlett James G Wagner Ryan P Lewandowski Abby D Benninghoff Ashleigh N Tindle Anna E Skedel Jack R Harkema James J Pestka Source Type: research