An Overview of Conventional and Black Cumin Seeds (Nigella sativa) Therapy in the Management of Nipah Viral Infection
Infect Disord Drug Targets. 2023 Oct 25. doi: 10.2174/0118715265258029231017112421. Online ahead of print.ABSTRACTThe recent outbreaks of Nipah viral infection were associated with severe respiratory illness, lethal encephalitis, and an extremely high mortality rate. As there are no approved antiviral medications, patients with NiV infections are currently treated with repurposed or investigational antivirals and supportive care. This review examines the potential health benefits of N. sativa in the treatment of NiV infection. To identify relevant studies, the literature was searched in online databases like Medline/PubMed...
Source: Infectious Disorders Drug Targets - October 27, 2023 Category: Infectious Diseases Authors: Naina Mohamed Pakkir Maideen Rajkapoor Balasubramaniam Mohamed Harsath Jahir Hussain Rupeshkumar Mani Thirumal Margesan Vasanth Kumar Solaimalai Source Type: research
An Overview of Conventional and Black Cumin Seeds (Nigella sativa) Therapy in the Management of Nipah Viral Infection
Infect Disord Drug Targets. 2023 Oct 25. doi: 10.2174/0118715265258029231017112421. Online ahead of print.ABSTRACTThe recent outbreaks of Nipah viral infection were associated with severe respiratory illness, lethal encephalitis, and an extremely high mortality rate. As there are no approved antiviral medications, patients with NiV infections are currently treated with repurposed or investigational antivirals and supportive care. This review examines the potential health benefits of N. sativa in the treatment of NiV infection. To identify relevant studies, the literature was searched in online databases like Medline/PubMed...
Source: Infectious Disorders Drug Targets - October 27, 2023 Category: Infectious Diseases Authors: Naina Mohamed Pakkir Maideen Rajkapoor Balasubramaniam Mohamed Harsath Jahir Hussain Rupeshkumar Mani Thirumal Margesan Vasanth Kumar Solaimalai Source Type: research
Therapeutic Potential and Pharmacological Activities of (+)-Nantenine in Medicine: An Aporphine Class phytocomponent of Nandina domestica Thunberg
Infect Disord Drug Targets. 2023 Oct 20. doi: 10.2174/0118715265244269231010090316. Online ahead of print.ABSTRACTPlant material and their derived by products have been used in the medicine for the treatment of human disorders and complications. Plants give us a distinct class of natural compounds, commonly called secondary metabolites and better examples are the flavonoids, phenols, terpenoids, alkaloids, tannins, and carotenoids. Plant derived phytoproducts have been used for the treatment of human disorders in both traditional as well as modern medicine. Naturally occurring aporphines and their synthetic derivatives are...
Source: Infectious Disorders Drug Targets - October 26, 2023 Category: Infectious Diseases Authors: Dinesh Kumar Patel Kanika Patel Source Type: research
Murine Malaria Model: Ketoconazole Preventing Malaria while Proguanil and Sulfadoxine/Pyrimethamine Protected against Malaria-associated Anemia and Kidney Damage
CONCLUSION: Ketoconazole possesses prophylactic antimalarial activity with associated dose-related renal impairment. Sulfadoxine/pyrimethamine demonstrated renoprotective potentials, while PRG prevented malaria-associated anemia.PMID:37881078 | DOI:10.2174/0118715265239831231017080840 (Source: Infectious Disorders Drug Targets)
Source: Infectious Disorders Drug Targets - October 26, 2023 Category: Infectious Diseases Authors: Akeem Ademola Ayankunle Samuel Olumide Faniran Ojurongbe O Adekunle O C Source Type: research
Potential Neuroprotective Strategies using Smart Drug Delivery Systems for Alzheimer's Disease
CONCLUSION: The biology of the BBB and its processes of penetration must be carefully taken into account while creating DDSs. If we have a better grasp of the disease's mechanism, we might be able to overcome the shortcomings of current treatments for AD. Different DDSs show interesting properties for delivering medication tailored to the brain. This review paper examines the recent applications of DDSs in diverse domains. By selecting the best targeting vectors and optimizing the combination of carriers, multifunctionalized DDS may be produced, and these DDS have a significant impact on AD therapy potential. To develop DD...
Source: Infectious Disorders Drug Targets - October 24, 2023 Category: Infectious Diseases Authors: Javed Khan Shikha Yadav Md Aftab Alam Source Type: research
Potential Neuroprotective Strategies using Smart Drug Delivery Systems for Alzheimer's Disease
CONCLUSION: The biology of the BBB and its processes of penetration must be carefully taken into account while creating DDSs. If we have a better grasp of the disease's mechanism, we might be able to overcome the shortcomings of current treatments for AD. Different DDSs show interesting properties for delivering medication tailored to the brain. This review paper examines the recent applications of DDSs in diverse domains. By selecting the best targeting vectors and optimizing the combination of carriers, multifunctionalized DDS may be produced, and these DDS have a significant impact on AD therapy potential. To develop DD...
Source: Infectious Disorders Drug Targets - October 24, 2023 Category: Infectious Diseases Authors: Javed Khan Shikha Yadav Md Aftab Alam Source Type: research
Potential Neuroprotective Strategies using Smart Drug Delivery Systems for Alzheimer's Disease
CONCLUSION: The biology of the BBB and its processes of penetration must be carefully taken into account while creating DDSs. If we have a better grasp of the disease's mechanism, we might be able to overcome the shortcomings of current treatments for AD. Different DDSs show interesting properties for delivering medication tailored to the brain. This review paper examines the recent applications of DDSs in diverse domains. By selecting the best targeting vectors and optimizing the combination of carriers, multifunctionalized DDS may be produced, and these DDS have a significant impact on AD therapy potential. To develop DD...
Source: Infectious Disorders Drug Targets - October 24, 2023 Category: Infectious Diseases Authors: Javed Khan Shikha Yadav Md Aftab Alam Source Type: research
Non-antibiotic Treatment Modalities for Bacterial Vaginosis
This article aims to provide a review on the types and efficacy of various alternative, non-antimicrobial therapeutic regimens.PMID:37870053 | DOI:10.2174/0118715265250557231011065142 (Source: Infectious Disorders Drug Targets)
Source: Infectious Disorders Drug Targets - October 23, 2023 Category: Infectious Diseases Authors: Sarah Adelia Athaya Ardelia Devi Artami Susetiati Source Type: research
A Review on Comparison of Allopathic Medicines to other Drug Therapies in the Management of Asthma
Infect Disord Drug Targets. 2023 Oct 20. doi: 10.2174/0118715265249796231018050521. Online ahead of print.ABSTRACTAsthma, is a chronic disease of the airways and is characterized by exacerbations of bronchospasm and noticeable airway inflammation. Current asthma therapy has emerged from naturally occurring compounds through rational pharmaceutical advancements, and it is very beneficial. In this review, we have discussed the different drug therapies i.e., Ayurvedic, Homeopathic, Unani, and Allopathic affecting asthma treatment. Allopathic medicines are used as a controller medication for regular maintenance of asthma i.e.,...
Source: Infectious Disorders Drug Targets - October 23, 2023 Category: Infectious Diseases Authors: Ruchika Garg Mona Piplani Ashutosh Upadhayay Yogendra Singh Pankaj Bhateja Source Type: research
A Review on the Antibiotic Resistance of < em > Shigella < /em > Strains in Iran
Infect Disord Drug Targets. 2023 Aug 31. doi: 10.2174/1871526523666230811093114. Online ahead of print.ABSTRACTShigella infection is commonly related to diarrhea and has been a noteworthy source of morbidity and mortality worldwide. There is a wide range of symptoms associated with these contagious microorganisms, from watery diarrhea to fulminant dysentery manifesting with recurrent bloody stools, fever, and prostration. While the mortality rate from Shigellosis has decreased significantly during the past three decades, it remains a principal cause of death in the world. The use of antibiotics in Shigella treatment remark...
Source: Infectious Disorders Drug Targets - September 19, 2023 Category: Infectious Diseases Authors: Mahdi Shooraj Marziye Taheri Mohammadmahdi Karimi-Yazdi Source Type: research
Characteristics and Applications of Peptide Nucleic Acid in the Treatment of Infectious Diseases and the Effect of Antimicrobial Photodynamic Therapy on Treatment Effectiveness
Infect Disord Drug Targets. 2023 Aug 22. doi: 10.2174/1871526523666230724120957. Online ahead of print.ABSTRACTAntibiotic resistance is a growing global problem, so there is an urgent need for new antimicrobial agents and strategies. Peptide nucleic acid (PNA) oligomers could be designed and utilized as gene-specific oligonucleotides to target any infectious agents. Selectivity and high-affinity binding are the main properties of PNA. However, in therapeutic applications, intracellular delivery of peptide nucleic acids is still a challenge. In photodynamic therapy (PDT), which could be a useful adjunct to mechanical and an...
Source: Infectious Disorders Drug Targets - September 19, 2023 Category: Infectious Diseases Authors: Zahra Javanmard Maryam Pourhajibagher Abbas Bahador Source Type: research
A Review on the Antibiotic Resistance of < em > Shigella < /em > Strains in Iran
Infect Disord Drug Targets. 2023 Aug 31. doi: 10.2174/1871526523666230811093114. Online ahead of print.ABSTRACTShigella infection is commonly related to diarrhea and has been a noteworthy source of morbidity and mortality worldwide. There is a wide range of symptoms associated with these contagious microorganisms, from watery diarrhea to fulminant dysentery manifesting with recurrent bloody stools, fever, and prostration. While the mortality rate from Shigellosis has decreased significantly during the past three decades, it remains a principal cause of death in the world. The use of antibiotics in Shigella treatment remark...
Source: Infectious Disorders Drug Targets - September 19, 2023 Category: Infectious Diseases Authors: Mahdi Shooraj Marziye Taheri Mohammadmahdi Karimi-Yazdi Source Type: research
Characteristics and Applications of Peptide Nucleic Acid in the Treatment of Infectious Diseases and the Effect of Antimicrobial Photodynamic Therapy on Treatment Effectiveness
Infect Disord Drug Targets. 2023 Aug 22. doi: 10.2174/1871526523666230724120957. Online ahead of print.ABSTRACTAntibiotic resistance is a growing global problem, so there is an urgent need for new antimicrobial agents and strategies. Peptide nucleic acid (PNA) oligomers could be designed and utilized as gene-specific oligonucleotides to target any infectious agents. Selectivity and high-affinity binding are the main properties of PNA. However, in therapeutic applications, intracellular delivery of peptide nucleic acids is still a challenge. In photodynamic therapy (PDT), which could be a useful adjunct to mechanical and an...
Source: Infectious Disorders Drug Targets - September 19, 2023 Category: Infectious Diseases Authors: Zahra Javanmard Maryam Pourhajibagher Abbas Bahador Source Type: research
A Review on the Antibiotic Resistance of < em > Shigella < /em > Strains in Iran
Infect Disord Drug Targets. 2023 Aug 31. doi: 10.2174/1871526523666230811093114. Online ahead of print.ABSTRACTShigella infection is commonly related to diarrhea and has been a noteworthy source of morbidity and mortality worldwide. There is a wide range of symptoms associated with these contagious microorganisms, from watery diarrhea to fulminant dysentery manifesting with recurrent bloody stools, fever, and prostration. While the mortality rate from Shigellosis has decreased significantly during the past three decades, it remains a principal cause of death in the world. The use of antibiotics in Shigella treatment remark...
Source: Infectious Disorders Drug Targets - September 19, 2023 Category: Infectious Diseases Authors: Mahdi Shooraj Marziye Taheri Mohammadmahdi Karimi-Yazdi Source Type: research
Characteristics and Applications of Peptide Nucleic Acid in the Treatment of Infectious Diseases and the Effect of Antimicrobial Photodynamic Therapy on Treatment Effectiveness
Infect Disord Drug Targets. 2023 Aug 22. doi: 10.2174/1871526523666230724120957. Online ahead of print.ABSTRACTAntibiotic resistance is a growing global problem, so there is an urgent need for new antimicrobial agents and strategies. Peptide nucleic acid (PNA) oligomers could be designed and utilized as gene-specific oligonucleotides to target any infectious agents. Selectivity and high-affinity binding are the main properties of PNA. However, in therapeutic applications, intracellular delivery of peptide nucleic acids is still a challenge. In photodynamic therapy (PDT), which could be a useful adjunct to mechanical and an...
Source: Infectious Disorders Drug Targets - September 19, 2023 Category: Infectious Diseases Authors: Zahra Javanmard Maryam Pourhajibagher Abbas Bahador Source Type: research
