Perspective of Secondary Metabolites in Respect of Multidrug Resistance (MDR): A Review
Infect Disord Drug Targets. 2023 Nov 22. doi: 10.2174/0118715265210606231113105225. Online ahead of print.ABSTRACTAberrant and haphazard use of antibiotics has created the development of antimicrobial resistance which is a bizarre challenge for human civilization. This emerging crisis of antibiotic resistance for microbial pathogens is alarming all the nations posing a global threat to human health. It is difficult to treat bacterial infections as they develop resistance to all antimicrobial resistance. Currently used antibacterial agents inhibit a variety of essential metabolic pathways in bacteria, including macro-molecu...
Source: Infectious Disorders Drug Targets - November 30, 2023 Category: Infectious Diseases Authors: Aditi Kaushik Manish Kaushik Gagandeep Kaur Vrinda Gupta Source Type: research

Diagnosis and Management of Latent Tuberculosis Infection: Updates
Infect Disord Drug Targets. 2023 Nov 28. doi: 10.2174/0118715265275319231124053615. Online ahead of print.ABSTRACTIndia has the largest problem of tuberculosis (TB) infection globally (estimated at about 35-40 crores cases), and around 18-36 lakh develop active tuberculosis annually. Latent TB is defined as a state of persistent immune response to stimulation by Mycobacterium tuberculosis antigens with no evidence of clinically manifested active TB. The progression of a latent infection to active tuberculosis increases several-fold in children < 5 years of age and in people with some or the other form of an immunocompro...
Source: Infectious Disorders Drug Targets - November 30, 2023 Category: Infectious Diseases Authors: Satish Swain Arvind Kumar Vishal Kumar Vishwakarma Adarsh Aayilliath K Ankit Mittal Naveet Wig Source Type: research

Perspective of Secondary Metabolites in Respect of Multidrug Resistance (MDR): A Review
Infect Disord Drug Targets. 2023 Nov 22. doi: 10.2174/0118715265210606231113105225. Online ahead of print.ABSTRACTAberrant and haphazard use of antibiotics has created the development of antimicrobial resistance which is a bizarre challenge for human civilization. This emerging crisis of antibiotic resistance for microbial pathogens is alarming all the nations posing a global threat to human health. It is difficult to treat bacterial infections as they develop resistance to all antimicrobial resistance. Currently used antibacterial agents inhibit a variety of essential metabolic pathways in bacteria, including macro-molecu...
Source: Infectious Disorders Drug Targets - November 30, 2023 Category: Infectious Diseases Authors: Aditi Kaushik Manish Kaushik Gagandeep Kaur Vrinda Gupta Source Type: research

Diagnosis and Management of Latent Tuberculosis Infection: Updates
Infect Disord Drug Targets. 2023 Nov 28. doi: 10.2174/0118715265275319231124053615. Online ahead of print.ABSTRACTIndia has the largest problem of tuberculosis (TB) infection globally (estimated at about 35-40 crores cases), and around 18-36 lakh develop active tuberculosis annually. Latent TB is defined as a state of persistent immune response to stimulation by Mycobacterium tuberculosis antigens with no evidence of clinically manifested active TB. The progression of a latent infection to active tuberculosis increases several-fold in children < 5 years of age and in people with some or the other form of an immunocompro...
Source: Infectious Disorders Drug Targets - November 30, 2023 Category: Infectious Diseases Authors: Satish Swain Arvind Kumar Vishal Kumar Vishwakarma Adarsh Aayilliath K Ankit Mittal Naveet Wig Source Type: research

Perspective of Secondary Metabolites in Respect of Multidrug Resistance (MDR): A Review
Infect Disord Drug Targets. 2023 Nov 22. doi: 10.2174/0118715265210606231113105225. Online ahead of print.ABSTRACTAberrant and haphazard use of antibiotics has created the development of antimicrobial resistance which is a bizarre challenge for human civilization. This emerging crisis of antibiotic resistance for microbial pathogens is alarming all the nations posing a global threat to human health. It is difficult to treat bacterial infections as they develop resistance to all antimicrobial resistance. Currently used antibacterial agents inhibit a variety of essential metabolic pathways in bacteria, including macro-molecu...
Source: Infectious Disorders Drug Targets - November 30, 2023 Category: Infectious Diseases Authors: Aditi Kaushik Manish Kaushik Gagandeep Kaur Vrinda Gupta Source Type: research

Diagnosis and Management of Latent Tuberculosis Infection: Updates
Infect Disord Drug Targets. 2023 Nov 28. doi: 10.2174/0118715265275319231124053615. Online ahead of print.ABSTRACTIndia has the largest problem of tuberculosis (TB) infection globally (estimated at about 35-40 crores cases), and around 18-36 lakh develop active tuberculosis annually. Latent TB is defined as a state of persistent immune response to stimulation by Mycobacterium tuberculosis antigens with no evidence of clinically manifested active TB. The progression of a latent infection to active tuberculosis increases several-fold in children < 5 years of age and in people with some or the other form of an immunocompro...
Source: Infectious Disorders Drug Targets - November 30, 2023 Category: Infectious Diseases Authors: Satish Swain Arvind Kumar Vishal Kumar Vishwakarma Adarsh Aayilliath K Ankit Mittal Naveet Wig Source Type: research

Perspective of Secondary Metabolites in Respect of Multidrug Resistance (MDR): A Review
Infect Disord Drug Targets. 2023 Nov 22. doi: 10.2174/0118715265210606231113105225. Online ahead of print.ABSTRACTAberrant and haphazard use of antibiotics has created the development of antimicrobial resistance which is a bizarre challenge for human civilization. This emerging crisis of antibiotic resistance for microbial pathogens is alarming all the nations posing a global threat to human health. It is difficult to treat bacterial infections as they develop resistance to all antimicrobial resistance. Currently used antibacterial agents inhibit a variety of essential metabolic pathways in bacteria, including macro-molecu...
Source: Infectious Disorders Drug Targets - November 30, 2023 Category: Infectious Diseases Authors: Aditi Kaushik Manish Kaushik Gagandeep Kaur Vrinda Gupta Source Type: research

The Re-emergence of Diphtheria Amidst Multiple Outbreaks in Nigeria
Infect Disord Drug Targets. 2023 Nov 28. doi: 10.2174/0118715265251299231117045940. Online ahead of print.ABSTRACTDiphtheria, a vaccine-preventable disease, has resurfaced in Nigeria, where many outbreaks have been reported in recent years. The outbreaks have occurred across the country, including in areas with high vaccination coverage. Corynebacterium diphtheriae, the causal agent, is a highly contagious bacteria that can cause severe respiratory and systemic symptoms and can be fatal if not treated. The reemergence of diphtheria in Nigeria is most likely due to a combination of factors, including gaps in routine immuniz...
Source: Infectious Disorders Drug Targets - November 29, 2023 Category: Infectious Diseases Authors: Pius Omoruyi Omosigho Okesanya Olalekan John Olaniyi Abideen Adigun Hakeem Kayode Hassan Olaleke Noah Olabode Abioye Sunday Micheal Usman Abubakar Haruna Amandeep Singh Emery Manirambona Source Type: research

A Novel Potential Treatment for Diabetic Foot Ulcers and Non-Healing Ulcers - Case Series
CONCLUSION: Despite patients belonging to the old age group and having comorbidities like diabetes, still VG111 showed effective rapid wound healing, and that too without any scar formation in hardto- heal, infected, and non-infected wounds.PMID:38018183 | DOI:10.2174/0118715265260305231115112728 (Source: Infectious Disorders Drug Targets)
Source: Infectious Disorders Drug Targets - November 29, 2023 Category: Infectious Diseases Authors: Sarabpreet Singh Arun Kumar Aggarwal Rajendra Gudisa Priyam Batra Nitesh Kumar Rathi Vibha Madan Vipul Thakur Harish Sharma Rajesh Kumar Siddhant Khare Lipika Singhal Rama Chaudhry Neeraj Arora Hardeep Singh Jasjeet Kaur Ashish Sharma Ganesh N Dakhale Vij Source Type: research

Navigating Challenges: Triumphs of Track and Trace in India's Pharmaceutical Supply Chain
Infect Disord Drug Targets. 2023 Nov 17. doi: 10.2174/0118715265276880231113030814. Online ahead of print.NO ABSTRACTPMID:38013442 | DOI:10.2174/0118715265276880231113030814 (Source: Infectious Disorders Drug Targets)
Source: Infectious Disorders Drug Targets - November 28, 2023 Category: Infectious Diseases Authors: Animesh Ranjan None Gaurav Niraj Sandip Patil Amandeep Singh Source Type: research

Navigating Challenges: Triumphs of Track and Trace in India's Pharmaceutical Supply Chain
Infect Disord Drug Targets. 2023 Nov 17. doi: 10.2174/0118715265276880231113030814. Online ahead of print.NO ABSTRACTPMID:38013442 | DOI:10.2174/0118715265276880231113030814 (Source: Infectious Disorders Drug Targets)
Source: Infectious Disorders Drug Targets - November 28, 2023 Category: Infectious Diseases Authors: Animesh Ranjan None Gaurav Niraj Sandip Patil Amandeep Singh Source Type: research

A Comprehensive Review on Patents, Herbal Treatment and Clinical Trials on Acquired Immune Deficiency Syndrome
Infect Disord Drug Targets. 2023 Nov 20. doi: 10.2174/0118715265270311231113041807. Online ahead of print.ABSTRACTThis paper provides an outline of the Human immunodeficiency virus (HIV), its mechanism of action, and types of HIV/AIDS. Additionally, it offers recent advances and patent data on HIV medications and formulations for the last ten years. The HIV/AIDS patents describes how compounds can stop viruses from spreading and stop HIV from multiplying. It also gives information about monolithic tablets, fixed oral doses of triple HIV formulations, and drug delivery systems that use electrospun fibers. The patents also r...
Source: Infectious Disorders Drug Targets - November 22, 2023 Category: Infectious Diseases Authors: Sushen Singh Choudhary Sushma Verma Source Type: research

Nutritional Status in Leprosy Patients: A Systematic Review and Metaanalysis
CONCLUSION: This research increases our understanding of nutrition and leprosy. The results found that people with leprosy are nutritionally at a distinct disadvantage when compared to non-leprosy patients. It emphasises the several ways in which diet may generate circumstances that increase the risk of leprosy.PMID:37990432 | DOI:10.2174/0118715265263893231102114955 (Source: Infectious Disorders Drug Targets)
Source: Infectious Disorders Drug Targets - November 22, 2023 Category: Infectious Diseases Authors: Hemasri Velmurugan Pugazhenthan Thangaraju Source Type: research

A Comprehensive Review on Patents, Herbal Treatment and Clinical Trials on Acquired Immune Deficiency Syndrome
Infect Disord Drug Targets. 2023 Nov 20. doi: 10.2174/0118715265270311231113041807. Online ahead of print.ABSTRACTThis paper provides an outline of the Human immunodeficiency virus (HIV), its mechanism of action, and types of HIV/AIDS. Additionally, it offers recent advances and patent data on HIV medications and formulations for the last ten years. The HIV/AIDS patents describes how compounds can stop viruses from spreading and stop HIV from multiplying. It also gives information about monolithic tablets, fixed oral doses of triple HIV formulations, and drug delivery systems that use electrospun fibers. The patents also r...
Source: Infectious Disorders Drug Targets - November 22, 2023 Category: Infectious Diseases Authors: Sushen Singh Choudhary Sushma Verma Source Type: research

Nutritional Status in Leprosy Patients: A Systematic Review and Metaanalysis
CONCLUSION: This research increases our understanding of nutrition and leprosy. The results found that people with leprosy are nutritionally at a distinct disadvantage when compared to non-leprosy patients. It emphasises the several ways in which diet may generate circumstances that increase the risk of leprosy.PMID:37990432 | DOI:10.2174/0118715265263893231102114955 (Source: Infectious Disorders Drug Targets)
Source: Infectious Disorders Drug Targets - November 22, 2023 Category: Infectious Diseases Authors: Hemasri Velmurugan Pugazhenthan Thangaraju Source Type: research