Factors Associated with Mortality in Patients with Coronavirus Disease (COVID-19) in Babol, North of Iran
CONCLUSION: COVID-19 has different clinical features and can be an asymptomatic, mild, or severe disease. Thus, findings about the disease and the consequent outcomes differ in patients. Further studies are needed to evaluate the clinical features and consequences of COVID-19 infection.PMID:38343046 | DOI:10.2174/0118715265209731240129042916 (Source: Infectious Disorders Drug Targets)
Source: Infectious Disorders Drug Targets - February 12, 2024 Category: Infectious Diseases Authors: Mansour Babaei Behzad Heidari Hossein Ghorbani Zahra Ahmadnia Samaneh Rouhi Mahmoud Sadeghi Haddad Zavareh Source Type: research

Factors Associated with Mortality in Patients with Coronavirus Disease (COVID-19) in Babol, North of Iran
CONCLUSION: COVID-19 has different clinical features and can be an asymptomatic, mild, or severe disease. Thus, findings about the disease and the consequent outcomes differ in patients. Further studies are needed to evaluate the clinical features and consequences of COVID-19 infection.PMID:38343046 | DOI:10.2174/0118715265209731240129042916 (Source: Infectious Disorders Drug Targets)
Source: Infectious Disorders Drug Targets - February 12, 2024 Category: Infectious Diseases Authors: Mansour Babaei Behzad Heidari Hossein Ghorbani Zahra Ahmadnia Samaneh Rouhi Mahmoud Sadeghi Haddad Zavareh Source Type: research

Factors Associated with Mortality in Patients with Coronavirus Disease (COVID-19) in Babol, North of Iran
CONCLUSION: COVID-19 has different clinical features and can be an asymptomatic, mild, or severe disease. Thus, findings about the disease and the consequent outcomes differ in patients. Further studies are needed to evaluate the clinical features and consequences of COVID-19 infection.PMID:38343046 | DOI:10.2174/0118715265209731240129042916 (Source: Infectious Disorders Drug Targets)
Source: Infectious Disorders Drug Targets - February 12, 2024 Category: Infectious Diseases Authors: Mansour Babaei Behzad Heidari Hossein Ghorbani Zahra Ahmadnia Samaneh Rouhi Mahmoud Sadeghi Haddad Zavareh Source Type: research

Factors Associated with Mortality in Patients with Coronavirus Disease (COVID-19) in Babol, North of Iran
CONCLUSION: COVID-19 has different clinical features and can be an asymptomatic, mild, or severe disease. Thus, findings about the disease and the consequent outcomes differ in patients. Further studies are needed to evaluate the clinical features and consequences of COVID-19 infection.PMID:38343046 | DOI:10.2174/0118715265209731240129042916 (Source: Infectious Disorders Drug Targets)
Source: Infectious Disorders Drug Targets - February 12, 2024 Category: Infectious Diseases Authors: Mansour Babaei Behzad Heidari Hossein Ghorbani Zahra Ahmadnia Samaneh Rouhi Mahmoud Sadeghi Haddad Zavareh Source Type: research

Factors Associated with Mortality in Patients with Coronavirus Disease (COVID-19) in Babol, North of Iran
CONCLUSION: COVID-19 has different clinical features and can be an asymptomatic, mild, or severe disease. Thus, findings about the disease and the consequent outcomes differ in patients. Further studies are needed to evaluate the clinical features and consequences of COVID-19 infection.PMID:38343046 | DOI:10.2174/0118715265209731240129042916 (Source: Infectious Disorders Drug Targets)
Source: Infectious Disorders Drug Targets - February 12, 2024 Category: Infectious Diseases Authors: Mansour Babaei Behzad Heidari Hossein Ghorbani Zahra Ahmadnia Samaneh Rouhi Mahmoud Sadeghi Haddad Zavareh Source Type: research

Factors Associated with Mortality in Patients with Coronavirus Disease (COVID-19) in Babol, North of Iran
CONCLUSION: COVID-19 has different clinical features and can be an asymptomatic, mild, or severe disease. Thus, findings about the disease and the consequent outcomes differ in patients. Further studies are needed to evaluate the clinical features and consequences of COVID-19 infection.PMID:38343046 | DOI:10.2174/0118715265209731240129042916 (Source: Infectious Disorders Drug Targets)
Source: Infectious Disorders Drug Targets - February 12, 2024 Category: Infectious Diseases Authors: Mansour Babaei Behzad Heidari Hossein Ghorbani Zahra Ahmadnia Samaneh Rouhi Mahmoud Sadeghi Haddad Zavareh Source Type: research

Can an International Student Group at TUMS in Iran Be a Role Model in the Development of Applied Scientific Evidence in the Era of COVID-19 through Mentorship?
Infect Disord Drug Targets. 2024 Feb 7. doi: 10.2174/0118715265277394240124070914. Online ahead of print.NO ABSTRACTPMID:38323614 | DOI:10.2174/0118715265277394240124070914 (Source: Infectious Disorders Drug Targets)
Source: Infectious Disorders Drug Targets - February 7, 2024 Category: Infectious Diseases Authors: Seyed Ahmad Seyed Alinaghi Esmaeil Mehraeen Source Type: research

Exosomes: Friends or Foes in Microbial Infections?
Infect Disord Drug Targets. 2024 Jan 17. doi: 10.2174/0118715265264388231128045954. Online ahead of print.ABSTRACTThe use of new approaches is necessary to address the global issue of infections caused by drug-resistant pathogens. Antimicrobial photodynamic therapy (aPDT) is a promising approach that reduces the emergence of drug resistance, and no resistance has been reported thus far. APDT involves using a photosensitizer (PS), a light source, and oxygen. The mechanism of aPDT is that a specific wavelength of light is directed at the PS in the presence of oxygen, which activates the PS and generates reactive oxygen speci...
Source: Infectious Disorders Drug Targets - February 6, 2024 Category: Infectious Diseases Authors: Samane Teymouri Maryam Pourhajibagher Abbas Bahador Source Type: research

Different Strategies Targeting Gut Microbiota for the Management of Several Disorders: A Sustainable Approach
CONCLUSION: Although considerable steps in enhancing and understanding the mechanism of treatment with the help of gut microbiota are under progress, much diversified and elaborate research must be conducted in order to enhance and implement the use of GM with high effectiveness.PMID:38317473 | DOI:10.2174/0118715265267536231121095634 (Source: Infectious Disorders Drug Targets)
Source: Infectious Disorders Drug Targets - February 6, 2024 Category: Infectious Diseases Authors: Mahima Chowdhury Neil Raj Chaudhary Paranjeet Kaur Anju Goyal Sanjeev Kumar Sahu Source Type: research

Insight into the Natural Biomolecules (BMs): Promising Candidates as Zika Virus Inhibitors
Infect Disord Drug Targets. 2024 Feb 2. doi: 10.2174/0118715265272414231226092146. Online ahead of print.ABSTRACTZika virus (ZIKV) is among the relatively new infectious disease threats that include SARS-CoV2, coronavirus, monkeypox (Mpox) virus, etc. ZIKV has been reported to cause severe health risks to the fetus. To date, satisfactory treatment is still not available for the treatment of ZIKV infection. This review examines the last five years of work using natural biomolecules (BMs) to counteract the ZIKV through virtual screening and in vitro investigations. Virtual screening has identified doramectin, pinocembrin, he...
Source: Infectious Disorders Drug Targets - February 6, 2024 Category: Infectious Diseases Authors: Kiran Dobhal Ruchika Garg Alka Singh Amit Semwal Source Type: research

Mycobacterium flavescens Infection - An Unusual Case of Prosthetic Joint Infection
DISCUSSION: Mycobacterium spp. related PJIs manifest clinical features similar to other bacteria-causing PJIs, such as warm, indurated edema at the surgical site resulting in wound dehiscence and joint effusion. Diagnosis of Mycobacterium spp. related PJIs includes history and physical exami-nation findings, serum inflammatory markers, synovial fluid analysis, and culture. Concurrently with surgical interventions, utilization of antimicrobial agents provides additional control in My-cobacterium-related PJI. Mycobacterium flavescens should be included among other NTMs as a possible cause of PJIs.PMID:38314682 | DOI:10.2174/...
Source: Infectious Disorders Drug Targets - February 5, 2024 Category: Infectious Diseases Authors: Peter Holleb Srijisnu De Suresh Antony Source Type: research

An Insight into the Repurposing of Phytoconstituents obtained from Delhi's Aravalli Biodiversity Park as Antifungal Agents
The objective was to predict or repurpose phyto-based antifungal compounds based on a dual target inhibition approach (Sterol-14-αdemethylase and HSP-90) using a case study. In pursuit of repurposing the phytochemicals as antifungal agents, a team of researchers visited Aravalli Biodiversity Park (ABP), Delhi, India, to collect information on available medicinal plants. From 45 plants, a total of 1149 ligands were collected, and virtual screening was performed using Schrodinger Suite 2016 software to get 83 hits against both the target proteins: Sterol-14-α-demethylase and HSP-90. After analysis of docking results, ligan...
Source: Infectious Disorders Drug Targets - February 2, 2024 Category: Infectious Diseases Authors: Amanpreet Kaur Kalicharan Sharma Neetika Sharma Geeta Aggarwal Source Type: research

Actinomyces-induced Osteomyelitis of the Mandible - A Rare Disease
CONCLUSION: In summary, jaw osteomyelitis caused by Actinomyces should always be part of the differential diagnosis; as these organisms are commensal flora, the symptoms manifested are nonspecific, and such a diagnosis could be easily missed, resulting in delay of care and disease progression.PMID:38299277 | DOI:10.2174/0118715265275102231217155015 (Source: Infectious Disorders Drug Targets)
Source: Infectious Disorders Drug Targets - February 1, 2024 Category: Infectious Diseases Authors: Caleb Nieves-Velez Gilberto Rivera-Gonzalez Suresh Antony Source Type: research

Estimating Hidden Population Size of COVID-19 Using Respondent- Driven Sampling Method - A Systematic Review
CONCLUSIONS: In general, our study illustrates the efficacy of RDS sampling in the estimation of undetected asymptomatic cases with high cost-effectiveness due to its relatively trouble-free and low-cost methods of sampling the population. This method would be valuable in probable future epidemics.PMID:38299412 | DOI:10.2174/0118715265277789240110043215 (Source: Infectious Disorders Drug Targets)
Source: Infectious Disorders Drug Targets - February 1, 2024 Category: Infectious Diseases Authors: Seyed Ahmad Seyed Alinaghi Arian Afzalian Mohsen Dashti Afsaneh Ghasemzadeh Zohal Parmoon Ramin Shahidi Sanaz Varshochi Ava Pashaei Samaneh Mohammadi Fatemeh Khajeh Akhtaran Amirali Karimi Khadijeh Nasiri Esmaeil Mehraeen Daniel Hackett Source Type: research

Advancements in Nanotechnology for Enhanced Antifungal Drug Delivery: A Comprehensive Review
Infect Disord Drug Targets. 2024;24(2):e021123223053. doi: 10.2174/0118715265266257231022134933.ABSTRACTInfections caused by fungi can be mildly bothersome or fatal, causing life-threatening conditions or even death. Antifungal drugs have used synthetic chemicals, organic compounds, and phytoconstituents in their formulations to treat fungal infections. Research into novel antifungal drugs has progressed more rapidly than into antibacterial treatments. This can be attributed to the low resistance of fungal infections to antifungal bioactivities and the relatively low incidence of these diseases. Carrier systems based on na...
Source: Infectious Disorders Drug Targets - January 31, 2024 Category: Infectious Diseases Authors: Rajat Srivastava Ajay Kumar Singh Rawat Manoj Kumar Mishra Amit Kumar Patel Source Type: research