Schwannoma-like pleomorphic adenoma: A pathological quandary
Indian J Pathol Microbiol. 2024 Feb 19. doi: 10.4103/ijpm.ijpm_552_23. Online ahead of print.ABSTRACTPleomorphic adenoma usually presents as a painless growing mass in locations of the salivary glands and is notorious for local recurrence if previous surgical resection is incomplete. Schwannoma is a benign peripheral nerve tumor with microscopic features of sheets of spindle-shaped cells with nuclear palisading. However, when a pathologist encounters a salivary gland tumor with microscopic morphological features of biphasic components with areas of schwannoma-like morphology, it is crucial to make a prudent diagnosis by di...
Source: Indian Journal of Pathology and Microbiology - March 1, 2024 Category: Pathology Authors: Rashmi Gautam Reena Tomar Deepika Rana Nita Khurana Ishwar Singh Source Type: research

Hepatic and perihepatic PEComas: A study describing a series of five rare cases
CONCLUSIONS: This series highlights the fact that accurate histological diagnosis of hepatic or perihepatic PEComas is important to prevent unnecessary aggressive treatment, unlike primary hepatocellular carcinomas or hepatoid/epithelioid metastatic tumors.PMID:38427771 | DOI:10.4103/ijpm.ijpm_587_23 (Source: Indian Journal of Pathology and Microbiology)
Source: Indian Journal of Pathology and Microbiology - March 1, 2024 Category: Pathology Authors: P Vijayanirmala Rajni Yadav Surbhi Goyal Adarsh Barwad Subham Bhowmik Rohan Malik Sujoy Pal Raju Sharma Puja Sakhuja Prasenjit Das Source Type: research

Acute panmylelosis with myelofibrosis - A rare case report with review of literature
We present a case of a 44-year male who came with a short history of fever, generalised weakness, revealed pancytopenia with occasional circulating blast in the peripheral blood smear. Bone marrow aspirate was dry tap,biopsy revealed panmyelosis with myelofibrosis with increased (22%) blasts. Flowcytometric immunophenotyping, cytogenetics and molecular tests were undertaken. Together with clinical details, immunophenotypic profile, cytogenetics and molecular studies, the diagnosis of Acute panmyelosis with myelofibrosis was made and managed accordingly. 32 The WHO 2017 describes APMF as an acute panmyeloid proliferation wi...
Source: Indian Journal of Pathology and Microbiology - March 1, 2024 Category: Pathology Authors: Surbhi Dahiya Jyoti Kotwal Sabina Langer Amrita Saraf Pallavi Prakhar Deepika Gupta Nitin Gupta Vandana Arya Source Type: research

Papillary glioneuronal tumor: A rare case with recent updates as per 2021 CNS WHO 5th classification
Indian J Pathol Microbiol. 2024 Feb 19. doi: 10.4103/ijpm.ijpm_310_23. Online ahead of print.ABSTRACTThe papillary glioneuronal tumor is a WHO grade 1, rare neuronal-glial tumor and comprises 0.02% of all CNS tumors. Histologically, it is a mixture of glial and neuronal components showing a pseudopapillary pattern with hyalinized vessels. PGNT is considered a low-grade neoplasm, and surgical excision has been curative in most cases. In this paper, we report a new case of papillary glioneuronal tumor in a 44-year-old male having a divergent presentation, to analyze it due to the rarity of its occurrence as per the latest cl...
Source: Indian Journal of Pathology and Microbiology - March 1, 2024 Category: Pathology Authors: Bandana Mehrotra Mithlesh Bhargav Ashok Kapoor Shubhi Pandey Saumya Brij Vaibhav R Gopal Source Type: research

Direct immunofluorescence (DIF) versus immunohistochemical (IHC) staining of complements and immunoglobulins (Ig) in pemphigus group
CONCLUSION: We conclude that IHC is a useful tool in the diagnosis of PV with the highest sensitivity of IgG and C3d. The combination of IgG and C3d could replace the DIF in almost all of our cases, so IHC on FFPE sections be used as an alternative method to DIF.PMID:38427745 | DOI:10.4103/ijpm.ijpm_113_23 (Source: Indian Journal of Pathology and Microbiology)
Source: Indian Journal of Pathology and Microbiology - March 1, 2024 Category: Pathology Authors: Deepika Rana Nita Khurana Shramana Mandal Bijay Laxmi Sahoo Source Type: research