Indian Journal of Pathology and Microbiology This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Direct immunofluorescence (DIF) versus immunohistochemical (IHC) staining of complements and immunoglobulins (Ig) in pemphigus group
CONCLUSION: We conclude that IHC is a useful tool in the diagnosis of PV with the highest sensitivity of IgG and C3d. The combination of IgG and C3d could replace the DIF in almost all of our cases, so IHC on FFPE sections be used as an alternative method to DIF.PMID:38427745 | DOI:10.4103/ijpm.ijpm_113_23 (Source: Indian Journal of Pathology and Microbiology)
Source: Indian Journal of Pathology and Microbiology - March 1, 2024 Category: Pathology Authors: Deepika Rana Nita Khurana Shramana Mandal Bijay Laxmi Sahoo Source Type: research

Preoperative evaluation of red blood cell distribution width as a promising biomarker for discriminating between benign and malignant breast tumors and assessing breast cancer activity
CONCLUSIONS: The findings of this study suggest that RDW has the potential to serve as a biomarker for assessing breast cancer activity and could offer substantial advantages in clinical contexts. The present study is not without limitations, and the authors suggest that a larger multicenter prospective study be conducted to further validate it's efficacy over an extended duration.PMID:38427746 | DOI:10.4103/ijpm.ijpm_351_23 (Source: Indian Journal of Pathology and Microbiology)
Source: Indian Journal of Pathology and Microbiology - March 1, 2024 Category: Pathology Authors: Ajay Singh Thakur Chandrashekhar Indoria Ruby Sahu Pratima Kujur Renuka Gahine Source Type: research

Epstein-Barr virus (EBV) DNAemia in saliva of viral encephalitis and nasopharyngeal carcinoma patients
Indian J Pathol Microbiol. 2024 Feb 19. doi: 10.4103/ijpm.ijpm_356_23. Online ahead of print.ABSTRACTEpstein-Barr virus (EBV) is a lymphotropic virus that causes diseases ranging from a flu-like illness called infectious mononucleosis to nasopharyngeal carcinoma, Burkitt's lymphoma, and central nervous system (CNS) infection. Detection of EBV DNA is usually done using whole blood samples taken from the patients. We undertook the detection of EBV in blood, cerebrospinal fluid (CSF), and saliva by real-time quantitative PCR in two patients, one with a history of nasopharyngeal carcinoma, and the other having a case of viral ...
Source: Indian Journal of Pathology and Microbiology - March 1, 2024 Category: Pathology Authors: Nanditha Srinivasan Ramya Barani M Manickavasagan Padma Srikanth Source Type: research

Primitive myxoid mesenchymal tumor of infancy, an enigmatic entity: A case report
Indian J Pathol Microbiol. 2024 Feb 19. doi: 10.4103/ijpm.ijpm_471_23. Online ahead of print.ABSTRACTPrimitive myxoid mesenchymal tumor of infancy (PMMTI) is a rare soft tissue neoplasm of intermediate malignant potential occurring predominantly in infants and younger children. It can show aggressive local infiltration of surrounding structures and frequent relapses but rare metastasis. Morphologically, it is characterized by a proliferation of immature mesenchymal cells in a myxoid background with mild cytologic atypia and branching vessels. The tumor cells demonstrate immunoreactivity with vimentin and BCOR, however, are...
Source: Indian Journal of Pathology and Microbiology - March 1, 2024 Category: Pathology Authors: Malini Goswami Source Type: research

Comparison of molecular analysis results determined by next-generation sequencing to immunohistochemical indicators and clinicopathological parameters in prostate adenocarcinomas
CONCLUSION: Regarding prognosis prediction and treatment, identifying the molecular changes in genes playing roles in prostate cancer with next-generation sequencing is very important.PMID:38427749 | DOI:10.4103/ijpm.ijpm_361_23 (Source: Indian Journal of Pathology and Microbiology)
Source: Indian Journal of Pathology and Microbiology - March 1, 2024 Category: Pathology Authors: Merve Çırak Balta İbrahim Halil Erdoğdu Esin Oktay Nil Çulhac Source Type: research

Microteaching for CBME batch: A response from PG resident
Indian J Pathol Microbiol. 2024 Feb 19. doi: 10.4103/IJPM.IJPM_730_23. Online ahead of print.NO ABSTRACTPMID:38427751 | DOI:10.4103/IJPM.IJPM_730_23 (Source: Indian Journal of Pathology and Microbiology)
Source: Indian Journal of Pathology and Microbiology - March 1, 2024 Category: Pathology Authors: Heer Shah Sahjid Mukhida Rajashri Patil Shital Algule R Lekshmi Source Type: research

Evaluation of immunohistochemical expression of novel neuroendocrine marker INSM1 and histological tumor growth pattern in well-differentiated neuroendocrine tumors of the appendix: 15-year single tertiary center experience
CONCLUSIONS: INSM1 was positive in all A-WDNET morphological patterns and was 100% sensitive. INSM1 IHC can be used as an alternative to traditional neuroendocrine markers or in combination with the diagnosis of neuroendocrine tumors.PMID:38427752 | DOI:10.4103/ijpm.ijpm_514_23 (Source: Indian Journal of Pathology and Microbiology)
Source: Indian Journal of Pathology and Microbiology - March 1, 2024 Category: Pathology Authors: Ali Koyuncuer Tolga Canbak Aylin Acar Onur Şahin Source Type: research

Alpha-fetoprotein producing gastric cancer with divergent differentiation: Report of a rare case with review of literature
Indian J Pathol Microbiol. 2024 Feb 15. doi: 10.4103/ijpm.ijpm_389_23. Online ahead of print.ABSTRACTAlpha-fetoprotein-producing gastric cancer is a rare variant of gastric adenocarcinoma. This tumor is likely to be misdiagnosed, particularly in patients with liver metastasis. This rare subgroup of gastric carcinoma may show divergent differentiation on histology and may pose a diagnostic challenge to the pathologist. They have an aggressive course with a dismal prognosis.PMID:38427754 | DOI:10.4103/ijpm.ijpm_389_23 (Source: Indian Journal of Pathology and Microbiology)
Source: Indian Journal of Pathology and Microbiology - March 1, 2024 Category: Pathology Authors: Pritinanda Mishra Chinmayee Panigrahi Susama Patra Hemant K Nayak Manas K Panigrahi Subash C Samal Source Type: research

Multicystic renal dysplasia, a histomorphological spectrum: Seven years experience from a tertiary care hospital
CONCLUSION: This series has been presented to highlight the various histomorphological features of MCDK. MCDK can be managed conservatively in most of cases due to autoinvolution and, hence, needs to be differentiated from other close differentials like polycystic kidney disease, cystic nephroma, and cystic partially differentiated nephroblastoma in order to avoid unnecessary surgical intervention.PMID:38427756 | DOI:10.4103/ijpm.ijpm_202_23 (Source: Indian Journal of Pathology and Microbiology)
Source: Indian Journal of Pathology and Microbiology - March 1, 2024 Category: Pathology Authors: Kanika Gupta Shramana Mandal Varuna Mallya Meeta Singh Nita Khurana Yogesh K Sarin Source Type: research

Identification of hub genes and pathogenesis in Kawasaki disease based on bioinformatics analysis
CONCLUSIONS: These 13 key genes may mediate the occurrence and development of KD through various processes such as immune regulation, inflammatory response, glucose metabolism, autophagy, and apoptosis, which provide valuable references for the diagnosis and treatment of KD.PMID:38427757 | DOI:10.4103/ijpm.ijpm_524_23 (Source: Indian Journal of Pathology and Microbiology)
Source: Indian Journal of Pathology and Microbiology - March 1, 2024 Category: Pathology Authors: Min Cao Zhenhu Zhang Qian Liu Yuda Zhang Source Type: research

Crystallizing galactocele: A rare case report and review of literature
Indian J Pathol Microbiol. 2024 Feb 19. doi: 10.4103/ijpm.ijpm_278_23. Online ahead of print.ABSTRACTCrystallizing galactocele is an uncommon condition that produces a viscous, chalky substance on fine needle aspiration cytology. (FNAC). Both the diagnosis and the management of this illness include the use of FNAC. Here, we discuss the case of a 25-year-old nursing woman who experienced left breast edema lump for two years. The upper outer quadrant of the leftt breast was involved by the hard, small, non-tender, and movable enlargement. The lesion's FNAC produced a thick, milky, and chalky substance. Numerous semi-transpar...
Source: Indian Journal of Pathology and Microbiology - March 1, 2024 Category: Pathology Authors: Nisha Verma Nimish Gaur Shivali Awasthi Varun Bajaj Surabhi Sharma Saurabh Mahajan Source Type: research

Lipoblastoma of the lip
Indian J Pathol Microbiol. 2024 Feb 19. doi: 10.4103/ijpm.ijpm_841_23. Online ahead of print.ABSTRACTLipoblastomas are benign tumors arising from embryonic white fatty cells that continue to proliferate and develop during the postnatal period. It commonly affects children 3 years of age or younger, with the neck being the most frequent site in the head and neck region. Only 10% of cases are seen at 10 years or above. The etiopathogenesis of lipoblastomas is linked to polysomy and rearrangement of chromosome 8q11-13 with or without the involvement of the pleomorphic adenoma gene 1 (PLAG1) gene. Here, we report one of the fi...
Source: Indian Journal of Pathology and Microbiology - March 1, 2024 Category: Pathology Authors: Jochima Cota Richa R Borkar Jitisha J Savalkar Paul Chalakkal Anita Spadigam Source Type: research

Disseminated multiloculated peritoneal inclusion cysts: Bubble trouble in belly
Indian J Pathol Microbiol. 2024 Feb 19. doi: 10.4103/ijpm.ijpm_556_23. Online ahead of print.ABSTRACTMultiloculated peritoneal inclusion cysts, usually arise from peritoneal mesothelium lining the serous cavity of the abdomen, pelvis and retroperitoneum. These lesions can be incidentally found on imaging or during surgery, and confirmation of the diagnosis is done by radiological imaging, histomorphology and immunohistochemical findings. Although fewer than 200 cases of solitary peritoneal inclusion cysts have been reported, their occurrence in a disseminated fashion has hardly ever been described in literature. Herein, we...
Source: Indian Journal of Pathology and Microbiology - March 1, 2024 Category: Pathology Authors: Md A Osama Aditi Aggarwal Seema Rao Amitabh Yadav Ritu Verma Source Type: research

Jejunal calcifying fibrous tumor: A jigsaw puzzle with a pool of diagnostic dilemma
We present one such rare case of jejunal CFT at an unusual age, complicated by jejuno-jejunal intussusception resulting in acute intestinal obstruction.PMID:38427761 | DOI:10.4103/ijpm.ijpm_270_23 (Source: Indian Journal of Pathology and Microbiology)
Source: Indian Journal of Pathology and Microbiology - March 1, 2024 Category: Pathology Authors: Akshi Raj Madhuri Singh Archana C Buch Sushama Gurwale Source Type: research

A rare case of neglected parasitic zoonosis
Indian J Pathol Microbiol. 2024 Feb 19. doi: 10.4103/ijpm.ijpm_385_23. Online ahead of print.ABSTRACTInfections caused due to zoonotic hookworms are rare and are often under reported. Here we report a case of diarrheal disease caused by Ancylostoma ceylanicum, an important emerging zoonotic hookworm. There is limited knowledge about the epidemiology and disease burden of A. ceylanicum infections in Kerala. A 50-year-old male patient presented with complaints of loose stools for past five weeks. The laboratory investigations revealed a high total WBC count and eosinophil count. Diagnostic colonoscopy showed numerous worms w...
Source: Indian Journal of Pathology and Microbiology - March 1, 2024 Category: Pathology Authors: Amal Noufal Aiswarya Mukundan Reena John Source Type: research