Multicystic renal dysplasia, a histomorphological spectrum: Seven years experience from a tertiary care hospital
CONCLUSION: This series has been presented to highlight the various histomorphological features of MCDK. MCDK can be managed conservatively in most of cases due to autoinvolution and, hence, needs to be differentiated from other close differentials like polycystic kidney disease, cystic nephroma, and cystic partially differentiated nephroblastoma in order to avoid unnecessary surgical intervention.PMID:38427756 | DOI:10.4103/ijpm.ijpm_202_23 (Source: Indian Journal of Pathology and Microbiology)
Source: Indian Journal of Pathology and Microbiology - March 1, 2024 Category: Pathology Authors: Kanika Gupta Shramana Mandal Varuna Mallya Meeta Singh Nita Khurana Yogesh K Sarin Source Type: research

Identification of hub genes and pathogenesis in Kawasaki disease based on bioinformatics analysis
CONCLUSIONS: These 13 key genes may mediate the occurrence and development of KD through various processes such as immune regulation, inflammatory response, glucose metabolism, autophagy, and apoptosis, which provide valuable references for the diagnosis and treatment of KD.PMID:38427757 | DOI:10.4103/ijpm.ijpm_524_23 (Source: Indian Journal of Pathology and Microbiology)
Source: Indian Journal of Pathology and Microbiology - March 1, 2024 Category: Pathology Authors: Min Cao Zhenhu Zhang Qian Liu Yuda Zhang Source Type: research

Crystallizing galactocele: A rare case report and review of literature
Indian J Pathol Microbiol. 2024 Feb 19. doi: 10.4103/ijpm.ijpm_278_23. Online ahead of print.ABSTRACTCrystallizing galactocele is an uncommon condition that produces a viscous, chalky substance on fine needle aspiration cytology. (FNAC). Both the diagnosis and the management of this illness include the use of FNAC. Here, we discuss the case of a 25-year-old nursing woman who experienced left breast edema lump for two years. The upper outer quadrant of the leftt breast was involved by the hard, small, non-tender, and movable enlargement. The lesion's FNAC produced a thick, milky, and chalky substance. Numerous semi-transpar...
Source: Indian Journal of Pathology and Microbiology - March 1, 2024 Category: Pathology Authors: Nisha Verma Nimish Gaur Shivali Awasthi Varun Bajaj Surabhi Sharma Saurabh Mahajan Source Type: research

Lipoblastoma of the lip
Indian J Pathol Microbiol. 2024 Feb 19. doi: 10.4103/ijpm.ijpm_841_23. Online ahead of print.ABSTRACTLipoblastomas are benign tumors arising from embryonic white fatty cells that continue to proliferate and develop during the postnatal period. It commonly affects children 3 years of age or younger, with the neck being the most frequent site in the head and neck region. Only 10% of cases are seen at 10 years or above. The etiopathogenesis of lipoblastomas is linked to polysomy and rearrangement of chromosome 8q11-13 with or without the involvement of the pleomorphic adenoma gene 1 (PLAG1) gene. Here, we report one of the fi...
Source: Indian Journal of Pathology and Microbiology - March 1, 2024 Category: Pathology Authors: Jochima Cota Richa R Borkar Jitisha J Savalkar Paul Chalakkal Anita Spadigam Source Type: research

Disseminated multiloculated peritoneal inclusion cysts: Bubble trouble in belly
Indian J Pathol Microbiol. 2024 Feb 19. doi: 10.4103/ijpm.ijpm_556_23. Online ahead of print.ABSTRACTMultiloculated peritoneal inclusion cysts, usually arise from peritoneal mesothelium lining the serous cavity of the abdomen, pelvis and retroperitoneum. These lesions can be incidentally found on imaging or during surgery, and confirmation of the diagnosis is done by radiological imaging, histomorphology and immunohistochemical findings. Although fewer than 200 cases of solitary peritoneal inclusion cysts have been reported, their occurrence in a disseminated fashion has hardly ever been described in literature. Herein, we...
Source: Indian Journal of Pathology and Microbiology - March 1, 2024 Category: Pathology Authors: Md A Osama Aditi Aggarwal Seema Rao Amitabh Yadav Ritu Verma Source Type: research

Jejunal calcifying fibrous tumor: A jigsaw puzzle with a pool of diagnostic dilemma
We present one such rare case of jejunal CFT at an unusual age, complicated by jejuno-jejunal intussusception resulting in acute intestinal obstruction.PMID:38427761 | DOI:10.4103/ijpm.ijpm_270_23 (Source: Indian Journal of Pathology and Microbiology)
Source: Indian Journal of Pathology and Microbiology - March 1, 2024 Category: Pathology Authors: Akshi Raj Madhuri Singh Archana C Buch Sushama Gurwale Source Type: research

A rare case of neglected parasitic zoonosis
Indian J Pathol Microbiol. 2024 Feb 19. doi: 10.4103/ijpm.ijpm_385_23. Online ahead of print.ABSTRACTInfections caused due to zoonotic hookworms are rare and are often under reported. Here we report a case of diarrheal disease caused by Ancylostoma ceylanicum, an important emerging zoonotic hookworm. There is limited knowledge about the epidemiology and disease burden of A. ceylanicum infections in Kerala. A 50-year-old male patient presented with complaints of loose stools for past five weeks. The laboratory investigations revealed a high total WBC count and eosinophil count. Diagnostic colonoscopy showed numerous worms w...
Source: Indian Journal of Pathology and Microbiology - March 1, 2024 Category: Pathology Authors: Amal Noufal Aiswarya Mukundan Reena John Source Type: research

Syringoid eccrine carcinoma of the nipple in a male patient with lymph node metastasis: A case report
Indian J Pathol Microbiol. 2024 Feb 19. doi: 10.4103/ijpm.ijpm_716_23. Online ahead of print.ABSTRACTSyringoid eccrine carcinoma of nipple is an extremely rare neoplasm of adnexal origin with variable clinical appearance and diverse histologic findings. Syringoid eccrine carcinoma (SEC) is often a diagnostic dilemma due to its morphology and presentation. Usually, these malignancies arise as non-ulcerated nodules or plaques in the head & neck region including the trunk. They are locally aggressive and have an infiltrative growth pattern with a propensity for metastasis. SEC is characterized by syringoma-like tadpole mo...
Source: Indian Journal of Pathology and Microbiology - March 1, 2024 Category: Pathology Authors: Mukund Sable Nibedita Sahoo Chinamyee Panigrahi Pritinanda Mishra Pradeep Kumar Source Type: research

Correlation between intestinal stem cell niche changes and small bowel crypt failure in patients with treatment-na ïve celiac disease
CONCLUSIONS: Our data suggests that ISC niche failure is a plausible hypothesis for villous flattening in patients with CeD, resulting from pericrypt IgA anti-TG2 antibody complex-mediated stromal depletion.PMID:38427764 | DOI:10.4103/ijpm.ijpm_760_23 (Source: Indian Journal of Pathology and Microbiology)
Source: Indian Journal of Pathology and Microbiology - March 1, 2024 Category: Pathology Authors: Prasenjit Das Sudha Battu Lalita Mehra Alka Singh Muzaffar Ahmad Ashish Agarwal Ashish Chauhan Anam Ahmad Sreenivas Vishnubhatla Siddhartha Datta Gupta Vineet Ahuja Govind Makharia Source Type: research

Primary diffuse large B-cell lymphoma of the prostate: Histopathological diagnosis of a rare entity in the prostate
Indian J Pathol Microbiol. 2024 Feb 19. doi: 10.4103/ijpm.ijpm_325_23. Online ahead of print.ABSTRACTLymphoma of the prostate is rare whether it is primary extranodal lymphoma or secondary involvement of the prostate by primary lymphoma elsewhere. Of all the lymphomas of the prostate, primary lymphomas of the prostrate are very rare. Although less frequent, it should be a differential diagnosis when evaluating prostate tumors. Here, we report a case of a 61-year-old man who presented with hematuria with clot retention. A cystoscopy with clot removal and transurethral resection of the prostate (TURP) was performed. This bio...
Source: Indian Journal of Pathology and Microbiology - March 1, 2024 Category: Pathology Authors: Richa Sharma Sumit Bansal Aparna Gangoli Source Type: research

Staphylococcal scalded skin syndrome in neonate: Another face of CA-MRSA
Indian J Pathol Microbiol. 2024 Feb 19. doi: 10.4103/ijpm.ijpm_833_23. Online ahead of print.ABSTRACTStaphylococcal scalded skin syndrome (SSSS), also known as Ritter's disease, in its severe form occurs predominantly in infants and children. It is caused by infection with group II (often phage group 71) Staphylococcus aureus. The foci of infection include nasopharynx, less commonly umbilicus, urinary tract, superficial abrasion, conjunctivae, and blood. Staphylococci are non-motile, non-spore-forming, catalase-positive, gram-positive cocci that appear predominantly as grape-like clusters. Although this organism is frequen...
Source: Indian Journal of Pathology and Microbiology - March 1, 2024 Category: Pathology Authors: M Mohamadiya Rizwana S Shanmugapriya M Jaya Sudha B Appalaraju S Ramesh Source Type: research

Knowledge, attitudes, and practices toward COVID-19 and its prevention among medical and dental students in an educational institution in Telangana
CONCLUSION: Curriculum modifications and creative teaching strategies can fill the lacunae in the KAP scores. Medical and dental students, as torchbearers of the healthcare fraternity, can play a critical role in raising awareness during public health emergencies.PMID:38427767 | DOI:10.4103/ijpm.ijpm_582_23 (Source: Indian Journal of Pathology and Microbiology)
Source: Indian Journal of Pathology and Microbiology - March 1, 2024 Category: Pathology Authors: Preeti U Deshpande Anuradha Basavaraju Nagapraveen Veerapu Ashish Akula Source Type: research

Evaluation of the significance of tumor stromal patterns and peri-tumoral inflammation in head and neck squamous cell carcinoma with special reference to the Yamamoto-Kohama classification
CONCLUSION: SR and the tumor invasive pattern in HNSCC are related to prognosis and may indicate tumor aggressiveness.PMID:38427768 | DOI:10.4103/ijpm.ijpm_426_23 (Source: Indian Journal of Pathology and Microbiology)
Source: Indian Journal of Pathology and Microbiology - March 1, 2024 Category: Pathology Authors: Geet Bhuyan Prabir Hazarika Anju M Rabha Source Type: research

A serious warning: A case report on localized amyloidosis of the oral cavity
Indian J Pathol Microbiol. 2024 Feb 19. doi: 10.4103/ijpm.ijpm_720_23. Online ahead of print.ABSTRACTAmyloidosis is a relatively rare condition with an array of complex pathophysiology. Localized amyloidosis is a rare and benign condition that practically never results in any clinical repercussions in the head and neck area. Multiple soft nodules of the tongue, lip, and cheek are the most commonly described defining characteristics of localized oral amyloidosis. These nodules originate due to the proliferation of abnormally folded protein aggregates in the body's extracellular tissue compartments, which destroy organ struc...
Source: Indian Journal of Pathology and Microbiology - March 1, 2024 Category: Pathology Authors: Sharon John Priyambadha Subba Aravindhan Aramugam Shalini Gupta Richa Khanna Source Type: research

Schwannoma-like pleomorphic adenoma: A pathological quandary
Indian J Pathol Microbiol. 2024 Feb 19. doi: 10.4103/ijpm.ijpm_552_23. Online ahead of print.ABSTRACTPleomorphic adenoma usually presents as a painless growing mass in locations of the salivary glands and is notorious for local recurrence if previous surgical resection is incomplete. Schwannoma is a benign peripheral nerve tumor with microscopic features of sheets of spindle-shaped cells with nuclear palisading. However, when a pathologist encounters a salivary gland tumor with microscopic morphological features of biphasic components with areas of schwannoma-like morphology, it is crucial to make a prudent diagnosis by di...
Source: Indian Journal of Pathology and Microbiology - March 1, 2024 Category: Pathology Authors: Rashmi Gautam Reena Tomar Deepika Rana Nita Khurana Ishwar Singh Source Type: research