Baclofen-induced neurotoxicity in chronic kidney disease: Is there a safe dose ?
We report three cases of Baclofen induced encephalopathy in chronic kidney disease patients; two developed encephalopathy within 6–8 h after ingestion of a single tablet and third on 4th day of consuming 2.5 mg twice daily dose. All three cases recovered fully following haemodialysis treatment. (Source: Indian Journal of Nephrology)
Source: Indian Journal of Nephrology - January 28, 2022 Category: Urology & Nephrology Authors: Prem P Varma Geet Bajpai Source Type: research

ABO-incompatible repeat kidney transplantation: Coping with the & #39;twin immunological barrier & #39;
Narayan Prasad, Anand Chellapan, Anis Srivastava, Dharmendra Bhadauria, Anupama Kaul, Manas Patel, Amit GuptaIndian Journal of Nephrology 2022 32(1):82-86 A repeat renal transplantation is believed to confer the best survival advantage for allograft failure. The scarcity of matching donors at one end, coupled with the expanding pool of ABO-incompatible (ABOi) donors at the other end, lead us to consider the option of ABOi kidney re-transplantation. However, ABOi kidney re-transplantation is associated with heightened immunological risk due to the presence of two substantial immunological barriers. Concern, queries, and un...
Source: Indian Journal of Nephrology - January 28, 2022 Category: Urology & Nephrology Authors: Narayan Prasad Anand Chellapan Anis Srivastava Dharmendra Bhadauria Anupama Kaul Manas Patel Amit Gupta Source Type: research

An unusual presentation of multiple myeloma
We report the case of a patient who initially presented with recurrent epistaxis and then with myasthenia. It was only when he developed acute kidney injury 4 months after the initial presentation with epistaxis that a diagnosis of multiple myeloma was made. (Source: Indian Journal of Nephrology)
Source: Indian Journal of Nephrology - January 28, 2022 Category: Urology & Nephrology Authors: Ishan Parekh Zaheer A Virani Prashant Rajput Hepal Vora Shruti Tapiawala Bharat V Shah Source Type: research

Renal salt-wasting syndrome induced by neoadjuvant chemotherapy containing cisplatin & #8211; A case report
We report about a patient who developed hyponatremia, hypokalemia with excessive urinary excretion of sodium and potassium, renal glycosuria, and aminoaciduria on the third day of the first cycle of cisplatin-containing chemotherapy. (Source: Indian Journal of Nephrology)
Source: Indian Journal of Nephrology - January 28, 2022 Category: Urology & Nephrology Authors: N Jinsi A Vimala Sreeja S Nair R Arya Ranjani Ravi Source Type: research

Hypervitaminosis D and acute interstitial nephritis: Tale of injections
Vaibhav Tiwari, Veronica Arora, Jitendra Rajput, Anurag Gupta, Smita Divyaveer, Sunita Bijarnia-Mahay, Pallav Gupta, Vinant Bhargava, Manish Malik, Ashwani Gupta, Anil Kumar Bhalla, DS RanaIndian Journal of Nephrology 2022 32(1):71-75 A 33-year-old man came with nausea, vomiting and abdominal pain due to hypercalcaemia and renal dysfunction following two doses of intramuscular vitamin D injections. Levels of vitamin D were repeatedly above 300 ng/ml over a period of 10 months. Whole-body PET CT scan revealed a thin-walled collection in the right gluteal region. The patient refused a surgical intervention for the same. Aft...
Source: Indian Journal of Nephrology - January 28, 2022 Category: Urology & Nephrology Authors: Vaibhav Tiwari Veronica Arora Jitendra Rajput Anurag Gupta Smita Divyaveer Sunita Bijarnia-Mahay Pallav Gupta Vinant Bhargava Manish Malik Ashwani Gupta Anil Kumar Bhalla DS Rana Source Type: research

An unusual clinical manifestation of plasmablastic lymphoma in a renal transplant recipient
Devika Gupta, Satish Mendonca, Tathagata Chatterjee, Arti Trehan, Lavan Singh, Rohit Tewari, Arun Joshi, Arun DuaIndian Journal of Nephrology 2022 32(1):67-70 Plasmablastic lymphoma is a rapidly progressive CD20 negative large cell non-Hodgkin lymphoma with poor outcome. It occurs mostly in immunocompromised individuals and has a predilection for extranodal sites. They need to be differentiated from other entities sharing similar morphological features like poorly differentiated carcinoma, Burkitt's lymphoma, Alk positive large B cell lymphoma, Diffuse large B cell lymphoma, and anaplastic myeloma. EBV negativi...
Source: Indian Journal of Nephrology - January 28, 2022 Category: Urology & Nephrology Authors: Devika Gupta Satish Mendonca Tathagata Chatterjee Arti Trehan Lavan Singh Rohit Tewari Arun Joshi Arun Dua Source Type: research

Is ambulatory blood pressure monitoring required for elderly hemodialysis patients during the interdialytic period ? - Experience of a tertiary care center in South India
Conclusion: The prevalence of uncontrolled HT with blunted circadian rhythm was high as detected by ABPM in the interdialytic period among elderly hemodialysis patients and had a significant impact on mortality. Masked uncontrolled HT as measured by ABPM was not uncommon in patients with normal peridialytic BP. (Source: Indian Journal of Nephrology)
Source: Indian Journal of Nephrology - January 28, 2022 Category: Urology & Nephrology Authors: E Indhumathi Srivatsa Angraje Biswajith Mishra Jayakumar Macha Source Type: research

C1q nephropathy in children with nephrotic syndrome: Treatment strategies and outcomes
Conclusion: One out of seven children with difficult NS can have underlying C1qN. CNIs are most beneficial to attain and maintain remission. Renal functions remain normal in the majority. Along with C1q deposits, MCNS and FSGS patterns are seen equally and respond almost similarly to CNIs. (Source: Indian Journal of Nephrology)
Source: Indian Journal of Nephrology - January 28, 2022 Category: Urology & Nephrology Authors: Saumil Gaur Reeba Patrick Mahesha Vankalakunti Kishore Phadke Source Type: research

Assessment of risk factors and outcome of early versus late cytomegalovirus infection infection in living-related D & #43;/R & #43; renal allograft recipients
Conclusion: In D+/R + living renal transplant recipients, without routine CMV prophylaxis, late CMV infection had more tissue invasive disease and is associated with inferior graft function on long-term follow-up. (Source: Indian Journal of Nephrology)
Source: Indian Journal of Nephrology - January 28, 2022 Category: Urology & Nephrology Authors: Atul Srivastava Soumita Bagchi Sarman Singh Veena Balloni Sanjay Kumar Agarwal Source Type: research

ABO-incompatible kidney transplantation in India: A single-center experience of first hundred cases
Conclusion: ABOi kidney transplant patients had acceptable patient and graft survival as well as BPAR rates. With current preconditioning protocol, infection rate was high. (Source: Indian Journal of Nephrology)
Source: Indian Journal of Nephrology - January 28, 2022 Category: Urology & Nephrology Authors: Pranaw Kumar Jha Shyam Bihari Bansal Abhyudaysingh Rana Ashish Nandwani Ajay Kher Sidharth Sethi Manish Jain Dinesh Bansal Dinesh Kumar Yadav Ashwini Gadde Amit Kumar Mahapatra Puneet Sodhi Rajesh Ahlawat Vijay Kher Source Type: research

Skin colonizers and catheter associated blood stream infections in incident Indian dialysis patients
Conclusions: Three-fourths of HD patients were colonized by MDR bacteria prior to HD initiation. Despite the majority being persistently colonized by MDR gram-positive organisms, CABSIs were predominantly gram negative. (Source: Indian Journal of Nephrology)
Source: Indian Journal of Nephrology - January 28, 2022 Category: Urology & Nephrology Authors: Varun Agrawal Anna T Valson Yamuna Devi Bakthavatchalam Shailesh Kakde Anjali Mohapatra Vinoi George David Suceena Alexander Shibu Jacob John Antony Jude Prakash Balaji Veeraraghavan Santosh Varughese Source Type: research

Revisiting vasculopathy in lupus nephritis: A renal biopsy evaluation study
Conclusion: Vascular involvement is common in LN. Uncomplicated vascular immune deposits were common vasculopathies whereas true vasculitis was least common. The morphology and IF both need to be carefully screened for the diagnosis of vasculopathies. (Source: Indian Journal of Nephrology)
Source: Indian Journal of Nephrology - January 28, 2022 Category: Urology & Nephrology Authors: Ramya Lakshmi V Navatha Vangala Megha S Uppin Swarnalatha Gudithi Gangadhar Taduri Sree Bhushan Raju Source Type: research

Microalbuminuria and Urinary Neutrophil Gelatinase-associated Lipocalin (uNGAL) in human immunodeficiency virus infected children
Conclusions: uNGAL and urine microalbumin are useful biomarkers of early tubular and glomerular injury in children with HIV infection. (Source: Indian Journal of Nephrology)
Source: Indian Journal of Nephrology - January 28, 2022 Category: Urology & Nephrology Authors: Emine A Rahiman Pratap Kumar Patra Deepti Suri Amit Rawat Surjit Singh Source Type: research

Clinical profile and outcomes of coronavirus disease 2019 (COVID-19) in patients undergoing hemodialysis
Conclusions: This analysis confirms the previous reports of higher COVID-19-related mortality in the dialysis population and identifies older age, higher inflammatory markers, and greater degrees of radiological lung involvement to correlate with increased mortality. (Source: Indian Journal of Nephrology)
Source: Indian Journal of Nephrology - January 28, 2022 Category: Urology & Nephrology Authors: Tanuj Moses Lamech Govindasamy Nithya Dhanapalan Aiswarya Natarajan Gopalakrishnan Paulpandian Vathsalyan Shaji Sajmi Kamalakannan Goutham Ravindran Krishna Thanikachalam Dineshkumar Ramanathan Sakthirajan Jeyachandran Dhanapriya Rajendran Padmaraj Source Type: research

Laparoscopic versus open-surgery catheter placement in peritoneal dialysis patients: A meta-analysis of outcomes
In conclusion, the laparoscopic PDC placement procedure was superior to open surgery in regards to catheter malfunction. Additionally, the choice of treatment procedure should put in consideration factors such as cost and comfortability of the patient. (Source: Indian Journal of Nephrology)
Source: Indian Journal of Nephrology - January 28, 2022 Category: Urology & Nephrology Authors: Guled Abdijalil Shen Shuijuan Source Type: research