Dialyzer first use reaction with polysulfone membrane: Moving beyond ethylene oxide
Abraham TharakanIndian Journal of Nephrology 2021 31(4):398-401Acute anaphylactic/anaphylactoid reactions to dialyzers are uncommon. Indeed, they are thought to have decreased in incidence since the transition to more biocompatible dialyzer membranes and with the abandonment of ethylene oxide for sterilization of dialyzers. However, few recent Spanish studies suggest that the incidence actually remains the same. Here, we report two cases of dialyzer first use reactions that occurred with polysulfone dialyzers. These were not ethylene oxide sterilized dialyzers and the reactions were less intense/absent from the second reus...
Source: Indian Journal of Nephrology - August 20, 2021 Category: Urology & Nephrology Authors: Abraham Tharakan Source Type: research
Anti-nuclear antibody-negative lupus nephritis or post-infectious glomerulonephritis: Diagnostic dilemma in a young male
In this report, we describe the relevance of pathological patterns and the uncertainties of ANA positivity in making a diagnosis of SLE. (Source: Indian Journal of Nephrology)
Source: Indian Journal of Nephrology - August 20, 2021 Category: Urology & Nephrology Authors: Joyita Bharati Saif Quaiser Ritambhra Nada Raja Ramachandran Harbir Singh Kohli Manish Rathi Source Type: research
Managing active iupus nephritis during COVID-19 pandemic
We report safe management of patients with active LN with intense immunosuppression along with vigorous precautions amidst the COVID-19 pandemic. The role of hydroxychloroquine along with timely precautions needs to be further explored as protective measures against COVID-19 among systemic lupus erythematosus patients. (Source: Indian Journal of Nephrology)
Source: Indian Journal of Nephrology - August 20, 2021 Category: Urology & Nephrology Authors: Joyita Bharati Manish Rathi Raja Ramachandran Aman Sharma Ritambhra Nada Harbir S Kohli Source Type: research
Papillary renal cell carcinoma with sarcomatoid differentiation in a native kidney of transplant recipient: A case report and review of literature
We present a case of papillary RCC with sarcomatoid differentiation (SD) in a native kidney of renal transplant (RT) recipient. The coexistence of sarcomatoid variant with papillary RCC, as in our case, makes it a high grade (WHO/ISUP grade 4) and portends a poor prognosis. Relative aggressiveness and rarity of this variant histology in transplant recipients prompted us to report this case and carry out an extensive search of the available literature. (Source: Indian Journal of Nephrology)
Source: Indian Journal of Nephrology - August 20, 2021 Category: Urology & Nephrology Authors: Satish K Ranjan Ankur Mittal Sunil Kumar Sanjeev Kishore Tushar A Narain Kim J Mammen Source Type: research
Renal microvascular ischemia secondary to nonsteroidal anti-inflammatory drugs
We present a case of a 37-year-old woman with multiple NSAIDs intake over a short period for dysmenorrhea followed by the development of new-onset bilateral flank pain. Computed tomography revealed bilateral multiple renal infarcts. Renal function was normal. Investigations showed no cardiac or renal artery lesion and vasculitis work-up was negative. She was treated conservatively and further NSAID intake was avoided. Follow-up scan showed complete restoration of the blood flow in previously affected areas. Thus, microvascular ischemia secondary to NSAIDs was thought to be responsible. (Source: Indian Journal of Nephrology)
Source: Indian Journal of Nephrology - August 20, 2021 Category: Urology & Nephrology Authors: Sagar Kulkarni Vipul Chakurkar Valentine Lobo Source Type: research
Spot urine albumin creatinine ratio can be a predictor of cognitive function in type 2 diabetes mellitus
Conclusions: Spot uACR could be helpful in predicting cognitive decline in people with type 2 DM. (Source: Indian Journal of Nephrology)
Source: Indian Journal of Nephrology - August 20, 2021 Category: Urology & Nephrology Authors: Deepak Kumar Panigrahi Debasish Chaudhury Source Type: research
Outcomes of kidney transplantation in the elderly recipients
Conclusion: In the elderly patients who underwent kidney transplantation, satisfactory graft function, and patient survival were maintained over a period of 60 months. Urinary tract infections were common, and sepsis was the most common cause of death with a surviving allograft. The acute rejection and mortality rates were comparable to the literature published from India so far. (Source: Indian Journal of Nephrology)
Source: Indian Journal of Nephrology - August 20, 2021 Category: Urology & Nephrology Authors: Vinant Bhargava Priti Meena Krishna Agrawaal Lovy Gaur Devinder Rana Anil Bhalla Ashwani Gupta Manish Malik Anurag Gupta Digvijay Kumar Source Type: research
Clinical Utility of 24-h Ambulatory Blood Pressure Monitoring in Hospitalized Patients with Chronic Kidney Disease
Conclusion: Apart from mean systolic and diastolic BP, ABPM gives the extent of end-organ damage and insights into the need for control of 24 h BP in patients of CKD. (Source: Indian Journal of Nephrology)
Source: Indian Journal of Nephrology - August 20, 2021 Category: Urology & Nephrology Authors: Santosh B Salagre Nigarbi N. A. Ansari Vandana S Mali Source Type: research
Kidney transplantation with ABO-incompatible donors: A comparison with matched ABO compatible donor transplants
Conclusion: Outcomes of ABOiKTx were inferior to ABOcKTx but tends to improve as more experience is gained. Incidence of ABMR was higher but infections and surgical complications were comparable.This data provides evidence that ABOiKTx is viable option for those without a ABO compatible donor. (Source: Indian Journal of Nephrology)
Source: Indian Journal of Nephrology - August 20, 2021 Category: Urology & Nephrology Authors: Aniketh Prabhakar Sishir Gang Umapathi Hegde Abhijit Konnur Hardik Patel Mohan Rajapurkar Source Type: research
Comparative analysis between urinary calprotectin and serum creatinine for early detection of intrinsic acute kidney injury
Conclusion: Urinary level of calprotectin is a very sensitive biomarker for early diagnosis of intrinsic AKI in children and it can be used in intensive care units or anywhere critically ill children admitted to detect intrinsic AKI. Besides, this study shows that urine calprotectin may be a more sensitive and specific biomarker than serum creatinine in the early phases of intrinsic AKI. (Source: Indian Journal of Nephrology)
Source: Indian Journal of Nephrology - August 20, 2021 Category: Urology & Nephrology Authors: Marjan Vakili Daryoush Fahimi Seyed-Taher Esfahani Meysam Sharifzadeh Mastaneh Moghtaderi Source Type: research
Analgesia for pediatric arteriovenous fistula cannulation in hemodialytic patients: A comparison of lidocaine gel, lidocaine spray, and needle plate
Conclusion: Our study showed that the use of needle plate, lidocaine spray, and lidocaine gel are all equally effective ways in controlling the degree of pain in AVF needling in children undergoing HD. (Source: Indian Journal of Nephrology)
Source: Indian Journal of Nephrology - August 20, 2021 Category: Urology & Nephrology Authors: Yalda Ravanshad Mohaddeseh Golsorkhi Sahar Ravanshad Anoush Azarfar Mohammad Esmaeeli Alireza Ghodsi Source Type: research
Effect of vitamin D on urinary angiotensinogen level in early diabetic nephropathy
Conclusion: Significantly higher UAGT levels in EDN supports the role of intrarenal RAS activation. A significant decrease in UAGT level in the cholecalciferol group supports the beneficial role of vitamin D supplementation in the progression of EDN. (Source: Indian Journal of Nephrology)
Source: Indian Journal of Nephrology - August 20, 2021 Category: Urology & Nephrology Authors: Himansu Sekhar Mahapatra Adarsh Kumar Bindu Kulshreshtha Anubhuti Chitkara Anamika Kumari Source Type: research
Grafalon & #174; vs. Thymoglobulin & #174; as an induction agent in renal transplantation & #8211; A retrospective study
Conclusions: Grafalon (6 mg/kg dose) when used as an induction agent was associated with significantly higher rate of BPARs as compared to thymoglobulin (3 mg/kg dose) although with comparable short-term patient and death censored graft survival, graft function, and infection rates. (Source: Indian Journal of Nephrology)
Source: Indian Journal of Nephrology - August 20, 2021 Category: Urology & Nephrology Authors: Pranaw Kumar Jha Abhyudaysingh Rana Ajay Kher Shyam Bihari Bansal Sidharth Sethi Ashish Nandwani Manish Jain Dinesh Bansal Dinesh Kumar Yadav Ashwini Gadde Amit Kumar Mahapatra Puneet Sodhi Vijay Kher Source Type: research
Acquired pure red cell aplasia and recombinant erythropoietin
Somanath Padhi, Sandip K PandaIndian Journal of Nephrology 2021 31(4):331-335
Recombinant erythropoietin (rEPO)-associated immunologically driven acquired pure red cell aplasia (PRCA) is an underreported, potentially worsening clinical syndrome in the setting of treatment of anemia of chronic kidney disease. Most cases reported in world literature are related to different formulations of erythropoiesis-stimulating agents with an implication in diagnosis and management. This brief review highlights the clinical guidelines of rEPO usage in nephrology practice, the pathophysiologic mechanism of PRCA, clinical features, diagn...
Source: Indian Journal of Nephrology - August 20, 2021 Category: Urology & Nephrology Authors: Somanath Padhi Sandip K Panda Source Type: research
Lentiform fork sign in a child on hemodialysis
Radhika Chemmangattu Radhakrishnan, Susan Uthup, Liji Rajesh, Reeba George PulinilkunnathilIndian Journal of Nephrology 2021 31(3):329-330 (Source: Indian Journal of Nephrology)
Source: Indian Journal of Nephrology - June 19, 2021 Category: Urology & Nephrology Authors: Radhika Chemmangattu Radhakrishnan Susan Uthup Liji Rajesh Reeba George Pulinilkunnathil Source Type: research
