Banff classification from 1991 to 2019. A significant contribution to our understanding and reporting of allograft renal biopsies
Swarnalata GowrishankarIndian Journal of Nephrology 2022 32(1):1-7
The Banff schema of classification of renal allograft biopsies, first proposed at the meeting in Banff, Canada in 1991 has evolved through subsequent meetings held once in two years and is the internationally accepted scheme of classification which is consensual, current, validated and in clinical use. This review traces the evolution of the classification and our understanding of renal transplant pathology, with emphasis on alloimmune reactions. The proceedings of the meetings and the important studies which have shaped the classification are covered. (So...
Source: Indian Journal of Nephrology - January 28, 2022 Category: Urology & Nephrology Authors: Swarnalata Gowrishankar Source Type: research
Cyst-like tumors in renal osteodystrophy
Gioacchino Li Cavoli, Francesca Finazzo, Rosalia Mongiovi', Barbara Oliva, Vitalba Azzolina, Tancredi Vincenzo Li CavoliIndian Journal of Nephrology 2021 31(6):595-596 (Source: Indian Journal of Nephrology)
Source: Indian Journal of Nephrology - December 9, 2021 Category: Urology & Nephrology Authors: Gioacchino Li Cavoli Francesca Finazzo Rosalia Mongiovi & #39; Barbara Oliva Vitalba Azzolina Tancredi Vincenzo Li Cavoli Source Type: research
Anti-thymocyte globulin induced acute lung injury in a case of renal allograft recipient
Nimish Gupta, Sagar Gupta, Ritesh Mongha, Sanjay AggarwalIndian Journal of Nephrology 2021 31(6):592-594 (Source: Indian Journal of Nephrology)
Source: Indian Journal of Nephrology - December 9, 2021 Category: Urology & Nephrology Authors: Nimish Gupta Sagar Gupta Ritesh Mongha Sanjay Aggarwal Source Type: research
Successful treatment of severe heart failure in advanced diabetic kidney disease using angiotensin & #8211;neprilysin inhibitors (sacubitril/valsartan) & #8211; report of two cases with review of options in literature
We report two cases of HF with reduced ejection fraction, who received ARNI in advanced stage of CKD (stage 5) and achieved remarkable outcomes in terms of quality of life and longevity. (Source: Indian Journal of Nephrology)
Source: Indian Journal of Nephrology - December 9, 2021 Category: Urology & Nephrology Authors: Ratan Jha Kiran K Mukku Ambati K Rakesh Sumeet Sinha Source Type: research
MHC Class I related chain A (MICA) Antibodies - A potential cause of renal allograft rejection
Ajay Kumar Baranwal, Sanjay Kumar Agarwal, Narinder MehraIndian Journal of Nephrology 2021 31(6):583-586
MHC class I related chain A (MICA) antibodies, especially those directed against the donor in absence of donor-specific anti-HLA antibodies have been reported to be possibly associated with renal allograft rejection in sensitized recipients. We are the first ones to present a case series of five patients who underwent primary live related donor renal transplantation in non-sensitized recipients either in the presence of donor-specific MICA antibodies (MICA-DSA) or developed de novo. Four of them presented characteristi...
Source: Indian Journal of Nephrology - December 9, 2021 Category: Urology & Nephrology Authors: Ajay Kumar Baranwal Sanjay Kumar Agarwal Narinder Mehra Source Type: research
Passenger lymphocyte syndrome after renal transplant: Case report
We report a case of 26-year-old male who underwent renal transplant. His mother as donor was O positive while he was A positive. He developed anemia at 1-week post-transplant, which later turned out to be PLS. Laboratory findings included rapidly decreasing Hb level and intravascular hemolysis. Hemolysis was brief, because the lymphocytes passed on with the donor organ were able to proliferate only for a while. The case signifies the importance of PLS as a cause for anemia, specifically in the early period after solid organ transplant. It is usually self-limiting, and the treatment requires blood transfusion of donor...
Source: Indian Journal of Nephrology - December 9, 2021 Category: Urology & Nephrology Authors: Bhavin S Mandowara Mehul R Mazumdar Himanshu A Patel Prakash I Darji Source Type: research
Modalities of diagnosis and management of peritoneal dialysis-related hydrothorax including videothoracoscopy-assisted repair: A single-center experience
We report clinical characteristics, pleural fluid chemistry patterns, diagnostic modality, management options, and outcomes in 12 patients who have confirmed pleuroperitoneal communication after the inception of the PD program at our institute. The incidence of PDRH in our study was 0.64%. The interval between initiation of PD and hydrothorax ranged from 7 weeks to 40 weeks (average 20.6 weeks). Ten (83.3%) had right-sided, one (8.3%) left-sided, and one (8.3%) bilateral hydrothorax. Most patients (83.3%) had dyspnea with chest symptoms, but two (16.6%) pati...
Source: Indian Journal of Nephrology - December 9, 2021 Category: Urology & Nephrology Authors: Narayan Prasad Manas Ranjan Patel Ravi Kushwaha Manas Ranjan Behera Monika Yachcha Anupama Kaul Dharmendra Bhadauria Suresh Kumar Amit Gupta Source Type: research
Tacrolimus-induced epidermoid cysts in the renal transplant patient
Vaibhav Tiwari, Anurag Gupta, Chetna Gothwal, Devinder S Rana, Vinant Bhargava, Manish Malik, Ashwani Gupta, Anil K BhallaIndian Journal of Nephrology 2021 31(6):571-573
Epidermal cysts are common benign cystic lesions that occur mostly sporadically. Common sites involved are arms, face, and trunk. The cyst may progress slowly and remain for years. These cysts arise as a result of the plugging of the follicular orifice. Etiology has largely remained unknown although local trauma, ultraviolet rays, and human papilloma virus (HPV) have been implicated in a few cases. Calcineurin inhibitors (CNIs) especially cyclosporine has...
Source: Indian Journal of Nephrology - December 9, 2021 Category: Urology & Nephrology Authors: Vaibhav Tiwari Anurag Gupta Chetna Gothwal Devinder S Rana Vinant Bhargava Manish Malik Ashwani Gupta Anil K Bhalla Source Type: research
Rare case report of de-novo pauci-immune necrotizing crescentic glomerulonephritis in 1st-week post-kidney transplantation
We report this patient who developed probable pauci-immune de-novo NCGN which responded to treatment with plasmapheresis, steroids and cyclophosphamide. (Source: Indian Journal of Nephrology)
Source: Indian Journal of Nephrology - December 9, 2021 Category: Urology & Nephrology Authors: Deepesh Vellakampadi Vishwanath Siddini Mahesh Vankalakunti Kishore Babu H Sudarshan Ballal Source Type: research
Nephrocalcinosis & #8212;A gateway to the diagnosis
Mahendra Atlani, Nirendra Rai, Abhijeet Kohat, Vaibhav Ingle, Agrata Sharma, P AparnaIndian Journal of Nephrology 2021 31(6):562-565
Nephrocalcinosis (NC) is the augmented calcium content within the renal parenchyma. Its pathogenesis mainly involves hypercalciuria. The presence of medullary NC provides a window to the clinician for the diagnosis of many important diseases. In this case series, we highlight three diseases that could be diagnosed with a high index of suspicion and detailed evaluation after their presentation as medullary NC. (Source: Indian Journal of Nephrology)
Source: Indian Journal of Nephrology - December 9, 2021 Category: Urology & Nephrology Authors: Mahendra Atlani Nirendra Rai Abhijeet Kohat Vaibhav Ingle Agrata Sharma P Aparna Source Type: research
Thrombotic microangiopathy causing acute kidney injury in a COVID-19 patient
Amitabh Kulkarni, Prashant Nasa, Srinivasa Polumuru, Aanchal SinghIndian Journal of Nephrology 2021 31(6):559-561
Acute Kidney Injury (AKI) in COVID-19 patients is common and independently associated with higher mortality. The pathophysiology of AKI is multifactorial and may be either direct viral trophism or immune mediated injury and hypercoagulability. This case highlights AKI in a young female with severe COVID-19 due to complement-3 mediated thrombotic microangiopathy with pre-existing chronic kidney disease likely because of IgA nephropathy. (Source: Indian Journal of Nephrology)
Source: Indian Journal of Nephrology - December 9, 2021 Category: Urology & Nephrology Authors: Amitabh Kulkarni Prashant Nasa Srinivasa Polumuru Aanchal Singh Source Type: research
Continuous hemodiafiltration with the oxiris filter ameliorates cytokine storm and induces rapid clinical improvement in COVID-19 & #8211; A case report
We describe a novel method of treatment in a patient with multiorgan involvement in COVID 19, using the oXiris hemofilter which delivers renal replacement therapy while also reducing cytokines like IL-6. (Source: Indian Journal of Nephrology)
Source: Indian Journal of Nephrology - December 9, 2021 Category: Urology & Nephrology Authors: Valentine A Lobo Arati Lokhande Vipul Chakurkar Pradeep M D & #39;Costa Source Type: research
Hypertension- one size does not fit all
Mohanasundaram Subashri, M Edwin Fernando, K ThirumalvalavanIndian Journal of Nephrology 2021 31(6):550-554
Although the vast majority of hypertension is "essential," some may be secondary. And, an accurate diagnosis of secondary cause of hypertension provides the treating clinician with a unique opportunity that renders dramatic response to the patient, either with pharmacologic therapy or surgery. One such secondary cause of hypertension is congenital adrenal hyperplasia due to 11 beta hydroxylase or 17 alpha hydroxylase deficiency. These inherited syndromes are caused by deficient adrenal corticos...
Source: Indian Journal of Nephrology - December 9, 2021 Category: Urology & Nephrology Authors: Mohanasundaram Subashri M Edwin Fernando K Thirumalvalavan Source Type: research
From infection to immunity - Impact of COVID-19 across nine hemodialysis centres in Mumbai
Conclusions: Testing a patient only when symptomatic, identified only 26% (13/50) of infected patients. For every single symptomatic patient who tested positive, there were 3 other asymptomatic infected ones. There was a high seroconversion rates in infected subjects. But antibodies also developed in asymptomatic subjects, indicating silent transmission and antibody generation in this population. (Source: Indian Journal of Nephrology)
Source: Indian Journal of Nephrology - December 9, 2021 Category: Urology & Nephrology Authors: Viswanath Billa Jatin Kothari Shrirang Bichu Rajesh Kumar Deepa Usulumarty Parag Tilve Sundaram Hariharan Source Type: research
A prospective study of emphysematous pyelonephritis in patients with type 2 diabetes
Conclusions: We recommend early aggressive medical treatment of EPN. Altered sensorium, renal obstruction, and deteriorating renal function may suggest the failure of medical treatment. (Source: Indian Journal of Nephrology)
Source: Indian Journal of Nephrology - December 9, 2021 Category: Urology & Nephrology Authors: Nadeema Rafiq Tauseef Nabi Shahnawaz Rasool Rayees Yousuf Sheikh Source Type: research
