Chronic Kidney Diseases of Unknown Etiology (CKDu) Hot spot at Narsinghpur and Badamba blocks in costal Districts of Odisha, India
Himansu Sekhar Mahapatra, Neeraj InamdarIndian Journal of Nephrology 2021 31(3):327-328 (Source: Indian Journal of Nephrology)
Source: Indian Journal of Nephrology - June 19, 2021 Category: Urology & Nephrology Authors: Himansu Sekhar Mahapatra Neeraj Inamdar Source Type: research

From hesitancy to certainty: A case of successful desensitization in high risk HLA incompatible kidney transplantation
Prashant Pandey, Divya Setya, Vijay K Sinha, Amit K Devra, Amit Pande, Praveen Kumar, Shweta RanjanIndian Journal of Nephrology 2021 31(3):324-326 (Source: Indian Journal of Nephrology)
Source: Indian Journal of Nephrology - June 19, 2021 Category: Urology & Nephrology Authors: Prashant Pandey Divya Setya Vijay K Sinha Amit K Devra Amit Pande Praveen Kumar Shweta Ranjan Source Type: research

Extramedullary hematopoiesis: An unusual cause for acute kidney injury
Anila Abraham Kurien, Dinesh Kumar Thanigachalam, Natarajan GopalakrishnanIndian Journal of Nephrology 2021 31(3):322-323 (Source: Indian Journal of Nephrology)
Source: Indian Journal of Nephrology - June 19, 2021 Category: Urology & Nephrology Authors: Anila Abraham Kurien Dinesh Kumar Thanigachalam Natarajan Gopalakrishnan Source Type: research

Recurrent, atypical anti-glomerular basement membrane disease
Jagadish S Jamboti, Rajalingam Sinniah, Lloyd Dorsogna, Christian HolmesIndian Journal of Nephrology 2021 31(3):319-321 Anti-glomerular basement membrane disease (GBM) (Goodpasture's disease) typically presents with acute manifestations of rapidly progressive glomerulonephritis often accompanied by lung haemorrhage. Anti-GBM disease is usually monophasic. However, atypical presentations with indolent renal involvement are being increasingly recognized. Herein we report a patient who presented with lung haemorrhage, minimal renal involvement, and negative result for serum anti-GBM antibody, while immunofluoresce...
Source: Indian Journal of Nephrology - June 19, 2021 Category: Urology & Nephrology Authors: Jagadish S Jamboti Rajalingam Sinniah Lloyd Dorsogna Christian Holmes Source Type: research

Adenovirus-associated thrombotic microangiopathy and necrotizing interstitial nephritis in a renal transplant recipient: A case report and review
We present a case of fever and graft dysfunction in a deceased donor renal transplant recipient whose initial post-operative period was complicated by vascular thrombosis and ureteric necrosis. He had received induction immunosuppression with Rabbit-Anti Thymocyte Globulin. Graft biopsy was suggestive of Thrombotic Microangiopathy (TMA) accompanied by intense interstitial inflammation, hemorrhage, necrosis, WBC casts and tubular injury. Viral cytopathic changes were discernible on light microscopy, leading to suspicion of adenoviral infection. This was confirmed with immunohistochemical demonstration of adenoviral antigens...
Source: Indian Journal of Nephrology - June 19, 2021 Category: Urology & Nephrology Authors: Harshavardhan T Sanathkumar Anila Abraham Kurien Yashwanth T Raj Edwin M Fernando Source Type: research

Blind bedside peritoneal dialysis catheter repositioning: An innovative technique
We describe an innovative technique of blind bedside PD catheter repositioning as a possible alternative to surgical repositioning when there is catheter malfunction. In 29 patients over a period of 3 years, we attempted blind bedside PD catheter repositioning with immediate successful inflow and outflow in all of them after repositioning. At 1 month, 21 (72.4%) patients had good catheter function and at 6 months, 19 (65.5%) patients were continuing successful PD. This bedside innovative procedure allowed for catheter salvage without constructing a new exit site or tunnel and without the requirement o...
Source: Indian Journal of Nephrology - June 19, 2021 Category: Urology & Nephrology Authors: Santosh Varughese Suceena Alexander Anna T Valson Anjali Mohapatra Vinoi G David Shibu Jacob Elenjickal E John Pradeep M Koshy Jeethu J Eapen Athul Thomas Sabina Yusuf Source Type: research

Renal hypouricemia with exercise induced acute kidney injury-A case report
We report a case of exercise-induced AKI secondary to renal hypouricemia. (Source: Indian Journal of Nephrology)
Source: Indian Journal of Nephrology - June 19, 2021 Category: Urology & Nephrology Authors: Srikanth Gundlapalli Yogesh Gaur M Venkateswar Rao Sujeeth Reddy Bande P Sandhya Source Type: research

Association of acute interstitial nephritis with nivolumab in renal cell carcinoma: A case report
We report the case of a 71-year-old female with metastatic renal carcinoma who underwent nephrectomy. After three lines of other chemotherapies (VEGF and mTOR inhibitors), the patient was treated by nivolumab (3 mg/kg) for 4 months and developed acute kidney injury 16 weeks after initiating this immunotherapy. Kidney biopsy displayed a diffuse extensive interstitial inflammation associated with moderate interstitial edema. The discontinuation of nivolumab and the administration of prednisone (at 1 mg/kg and tapered over 3 months) was an effective treatment of the interstitial edema and led to the recovery of the kidney fun...
Source: Indian Journal of Nephrology - June 19, 2021 Category: Urology & Nephrology Authors: Befa Noto-Kadou-Kaza Geoffroy Desbuissons Corinne Bagnis Isnard Source Type: research

Plasmapheresis in hypertriglyceride-induced pancreatitis: A series of four cases
Prawash Kumar Chowdhary, Sanjeev Anant KaleIndian Journal of Nephrology 2021 31(3):299-302 Hypertriglyceride-induced Acute Pancreatitis is a devasting condition. The rapid reduction of serum triglyceride is a key factor in its management. Beside the reduction in Triglyceride level plasmapheresis has other added advantage. Early initiation of plasmapheresis within 48 hrs has a better outcome. Plasmapheresis should be performed until triglyceride levels have been lowered to 500mg/dl. Here, we present a series of four cases of hypertriglyceride induced pancreatitis who underwent plasmapheresis. All the patients were diabetic...
Source: Indian Journal of Nephrology - June 19, 2021 Category: Urology & Nephrology Authors: Prawash Kumar Chowdhary Sanjeev Anant Kale Source Type: research

Spontaneous cerebrospinal fluid rhinorrhea in end stage renal disease
We report a case of spontaneous cerebrospinal fluid (CSF) rhinorrhea in a patient on maintenance hemodialysis. There was no previous history of trauma or surgery. Secondary hyperparathyroidism due to progression of chronic kidney disease (CKD) and a rise in intracranial pressure resulted in spontaneous cerebrospinal fluid rhinorrhea. He underwent endoscopic endonasal repair with theco-peritoneal shunt; CSF leak stopped completely and the patient is doing well on one year follow up. (Source: Indian Journal of Nephrology)
Source: Indian Journal of Nephrology - June 19, 2021 Category: Urology & Nephrology Authors: Balachandran P Jyothsna Kunjappa Vinod Kumar Narayanan V Unni Gopinath Praveen Joshua P Shejoy Bipi Prasannan Source Type: research

An unusual neurological syndrome in a haemodialysis patient
Nisha Jose, V Jayaprakash, A Deiva, M JayakumarIndian Journal of Nephrology 2021 31(3):293-295 Advanced age and immunosuppressed states allow for complications of herpes zoster such as encephalitis. In this case report, we describe a patient with encephalopathy two days after initiation of antiviral therapy. After the necessary imaging and cerebrospinal fluid (CSF) analysis, it became evident that the neurological syndrome was due to acyclovir. Despite currently practised renal dose modification, the patient developed acyclovir-induced neurotoxicity and required intensification of his dialysis schedule to eliminate the dr...
Source: Indian Journal of Nephrology - June 19, 2021 Category: Urology & Nephrology Authors: Nisha Jose V Jayaprakash A Deiva M Jayakumar Source Type: research

Association of IgA nephropathy with squamous cell carcinoma of the tongue: & #8211; Case report and review of literature
Harshavardhan T Sanathkumar, K Thirumalvalavan, T Yashwanth Raj, ND Srinivasaprasad, S Sujith, Edwin M FernandoIndian Journal of Nephrology 2021 31(3):290-292 A 32-year-old habitual tobacco chewer was diagnosed with squamous cell carcinoma of the tongue. He was initiated on chemo-radiation therapy. After completing 23 cycles of radiation and four cycles of cisplatin-based chemotherapy, he presented with acute nephritic syndrome. Renal biopsy showed IgA nephropathy and acute tubular injury. With supportive care, renal function stabilised with a reduction in proteinuria. We wish to highlight the poorly understood associatio...
Source: Indian Journal of Nephrology - June 19, 2021 Category: Urology & Nephrology Authors: Harshavardhan T Sanathkumar K Thirumalvalavan T Yashwanth Raj ND Srinivasaprasad S Sujith Edwin M Fernando Source Type: research

IGg4-related disease presenting as rapidly progressive renal failure and inguinal iymphadenopathy
Maniyar Iqbal Anvar, Jayaram N Iyenger, Shweta S Mehta, Biradar JagdeeshkumarIndian Journal of Nephrology 2021 31(3):286-289 A 58-year-old man presented with swelling in the left inguinal region and loss of appetite, nausea and azotemia with a serum creatinine of 5.2 mg/dL and urine albumin of 1+ and normal size kidneys with no hematuria. His serum creatinine increased to 9 mg/dL over 1 month, his total proteins were 10.8 and serum albumin was 3.3 g/dL, and lymph node excision biopsy showed fragments of lymphoid tissue with interfollicular areas containing sheets of plasma cells and atretic germinal centers. In...
Source: Indian Journal of Nephrology - June 19, 2021 Category: Urology & Nephrology Authors: Maniyar Iqbal Anvar Jayaram N Iyenger Shweta S Mehta Biradar Jagdeeshkumar Source Type: research

Two Cases of Vasculitis with Renal Vein Thrombosis
We present a series of two cases of ANCA associated Vasculitis (AAV) presenting as Pulmonary Renal syndrome with associated renal vein thrombosis. Although there are enough evidences suggesting association of venous thrombosis with AAVs, the incidence of renal vein thrombosis is rare. Renal vein thrombosis should be ruled out in cases where there is delay in recovery of renal function in patients with AAV. Positive laboratory values for anti-Proteinase-3 (PR3) and anti-Myeloperoxidase (MPO) ANCA in the cases that presented as Rapidly Progressive Glomerulonephritis, helped in early initiation of treatment with complete reco...
Source: Indian Journal of Nephrology - June 19, 2021 Category: Urology & Nephrology Authors: Mehul Mazumdar Bhavin S Mandowara Himanshu A Patel Prakash Darji Source Type: research

Development and validation of a novel food-frequency questionnaire for hemodialysis patients in Lucknow, India
Conclusion: This novel semiquantitative FFQ is a valid tool for measuring energy and nutrient intakes in hemodialysis patients. (Source: Indian Journal of Nephrology)
Source: Indian Journal of Nephrology - June 19, 2021 Category: Urology & Nephrology Authors: S Namrata Rao Abhilash Chandra Poonam Tiwari Prabhaker Mishra Source Type: research