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Valsartan Versus Amlodipine Effect on Left Ventricular Multidirectional Deformation and Adipocytokines Levels in Hypertensive Patients: Speckle Tracking Echocardiography
ConclusionsOur results indicate that valsartan is superior to amlodipine when it comes to affecting the hormonal function of human adipose tissue. Valsartan has a beneficial effect on LV deformation and function presented in GLS. (Source: High Blood Pressure and Cardiovascular Prevention)
Source: High Blood Pressure and Cardiovascular Prevention - July 22, 2020 Category: Cardiology Source Type: research

A Retrospective Chart Review Evaluating Efficacy, Tolerability, and Cost of Proprotein Convertase Subtilisin/Kexin Type 9 Inhibitors (PCSK9i) in Older Adults
ConclusionsPCSK9i are effective at lowering LDL-C in older adults. Tolerability was high among patients without a history of statin intolerance. PCSK9i remain high-cost medications to both insurance companies and patients in terms of cost-sharing responsibilities. (Source: High Blood Pressure and Cardiovascular Prevention)
Source: High Blood Pressure and Cardiovascular Prevention - July 9, 2020 Category: Cardiology Source Type: research

Vending Machines and Cardiovascular Prevention: How to Implement Healthy Dietary Habits at School
AbstractToo many children in Europe are overweight. The unregulated marketing of unhealthy products target to children, and the installation of vending machines stocked with unhealthy snacks in public venues, are contributing factors. While innovative legislation on the regulation of the nutritional quality of food and beverages sold in vending machines in schools has become law in some European countries, it is not on the political agenda in others. However, an easy alternative solution could be to introduce a clause in all new tenders for vending machines, which states that the successful supplier must commit to ensuring...
Source: High Blood Pressure and Cardiovascular Prevention - July 8, 2020 Category: Cardiology Source Type: research

Pharmacological Approach to Smoking Cessation: An Updated Review for Daily Clinical Practice
AbstractTobacco use is one of the major public health concerns and it is the most preventable cause of morbidity and mortality worldwide. Smoking cessation reduces subsequent cardiovascular events and mortality. Smoking is a real chronic disorder characterized by the development of an addiction status mainly due to nicotine. This condition makes the smokers generally unable to quit smoking without help. Different strategies are available to treat smoking dependence that include both non-pharmacological (behavioral counselling) and pharmacological therapies. Currently, it is well accepted that smoking cessation drugs are ef...
Source: High Blood Pressure and Cardiovascular Prevention - June 22, 2020 Category: Cardiology Source Type: research

Vascular Aging and Central Aortic Blood Pressure: From Pathophysiology to Treatment
AbstractLarge conductive arteries undergo to structural modifications by aging, eventually leading to increased vascular stiffness. As consequence, cardiovascular hemodynamic changes by increasing central blood pressure which may be also associated to the remodelling of peripheral resistance arteries that contribute to increase further the central vascular stiffness and blood pressure. These modifications resemble the ones that has been shown in essential hypertension, thus a condition of “early vascular aging” has been described in hypertensive patients. Since hypertension related target organs, particularly the heart...
Source: High Blood Pressure and Cardiovascular Prevention - June 21, 2020 Category: Cardiology Source Type: research

The Influence of Fasting and Energy Restricting Diets on Blood Pressure in Humans: A Systematic Review and Meta-Analysis
ConclusionThe principal finding of this study was that fasting and energy restricting diets elicited, overall, significant reductions in SBP and DBP. Subsequent subgroup analyses revealed that intervention duration  ≤ 12 weeks and fasting regimens more effectively reduced SBP and DBP. (Source: High Blood Pressure and Cardiovascular Prevention)
Source: High Blood Pressure and Cardiovascular Prevention - June 19, 2020 Category: Cardiology Source Type: research

Hypertension prevalence  in Colombian Patients Evaluated with Ambulatory Blood Pressure Monitoring According to Changes in Clinical Guidelines Between 2017–2018
ConclusionIf the measured value of blood pressure in the 24-h ABPM is taken into account, it would necessary to intervene pharmacologically 21.5% more individuals according to the ACC/AHA guidelines  in our population, Individualization is awarded. (Source: High Blood Pressure and Cardiovascular Prevention)
Source: High Blood Pressure and Cardiovascular Prevention - June 10, 2020 Category: Cardiology Source Type: research

Prevention of Sudden Cardiac Death: Focus on the Subcutaneous Implantable Cardioverter-Defibrillator
AbstractThe implantable cardioverter-defibrillator (ICD) is the most effective therapy to prevent sudden cardiac death (SCD) in high-risk patients. To overcome infections and failure of transvenous leads, the most frightening complications of conventional ICDs, a completely subcutaneous ICD (S-ICD) has been developed and is currently adopted in routine clinical practice. In view of their long life-expectancy, low competitive risk of dying from non-arrhythmic causes, and high lifetime risk of lead-related complications requiring surgical revisions, young patients with cardiomyopathies and inherited arrhythmia syndromes have...
Source: High Blood Pressure and Cardiovascular Prevention - June 8, 2020 Category: Cardiology Source Type: research

High Resolution Signal Averaged Electrocardiography May Improve Diagnosis of Atrial Fibrillation and Reduce Stroke
(Source: High Blood Pressure and Cardiovascular Prevention)
Source: High Blood Pressure and Cardiovascular Prevention - June 5, 2020 Category: Cardiology Source Type: research

Periodontitis and Hypertension: Is the Association Causal?
AbstractHigh blood pressure (BP) and periodontitis are two highly prevalent conditions worldwide with a significant impact on cardiovascular disease (CVD) complications. Poor periodontal health is associated with increased prevalence of hypertension and may have an influence on BP control. Risk factors such as older age, male gender, non-Caucasian ethnicity, smoking, overweight/obesity, diabetes, low socioeconomic status, and poor education have been considered the common denominators underpinning this relationship. However, recent evidence indicates that the association between periodontitis and hypertension is independen...
Source: High Blood Pressure and Cardiovascular Prevention - June 3, 2020 Category: Cardiology Source Type: research

Assessing Atrial Fibrillation Substrates by P Wave Analysis: A Comprehensive Review
AbstractAtrial fibrillation (AF) is the most common cardiac arrhythmia. Pharmacologic and non-pharmacologic rhythm control strategies impact on AF-related symptoms, while leaving largely unaffected the risk of stroke. Moreover, up to 20% of AF patients are asymptomatic during paroxysmal relapses of arrhythmia, thus underlying the need for early markers to identify at-risk patients and prevent cerebrovascular accidents. Indeed, non-invasive assessment of pre-clinical substrate changes that predispose to AF could provide early identification of at-risk patients and allow for tailored care paths. ECG-derived P wave analysis i...
Source: High Blood Pressure and Cardiovascular Prevention - May 24, 2020 Category: Cardiology Source Type: research

Evaluation of Cardiovascular Risk in Patient with Primary Non-alcoholic Fatty Liver Disease
ConclusionsSome of the methods for the estimation of cardiovascular risk (ACC/AHA ASCVD 2013, new model 2 2018, and, also Framingham score 2008) have a clear advantage over Framingham score 2004 and “Progetto Cuore” of the Italian Institute of Health in terms of correlation with the severity of NAFLD. They are, therefore, more clinically useful. (Source: High Blood Pressure and Cardiovascular Prevention)
Source: High Blood Pressure and Cardiovascular Prevention - May 19, 2020 Category: Cardiology Source Type: research

Is Arterial Stiffness a Determinant of Hypotension?
ConclusionsHypotension is a quite common phenomenon in older subjects. Its prevention requires a more accurate management of hypertension aimed at better identifying which older subjects in whom intensive BP control may be harmful and those who may benefit from it. (Source: High Blood Pressure and Cardiovascular Prevention)
Source: High Blood Pressure and Cardiovascular Prevention - May 7, 2020 Category: Cardiology Source Type: research

Multidisciplinary Consensus Document on the Management of Uncontrolled Hypertension in India
AbstractCardiovascular disease is predicted to be the largest cause of death and disability in India by 2020. Hypertension (HT), one of the main contributing factors, presents a significant public health burden. Inability to achieve adequate blood pressure (BP) control results in uncontrolled hypertension (UHT). The prevalence of UHT is high in India, with only about 9 –20% of patients achieving target BP goals. Presently, there are no guidelines specific to UHT, which if left uncontrolled can lead to resistant HT, chronic kidney disease and other complications of HT. A multidisciplinary panel, comprising of specialists ...
Source: High Blood Pressure and Cardiovascular Prevention - May 6, 2020 Category: Cardiology Source Type: research

Commentary on “Functional Improvement After Outpatient Cardiac Rehabilitation in Acute Coronary Syndrome Patients is not Related to Improvement in Left Ventricular Ejection Fraction”
(Source: High Blood Pressure and Cardiovascular Prevention)
Source: High Blood Pressure and Cardiovascular Prevention - May 6, 2020 Category: Cardiology Source Type: research