Prosthetic Replacement of the Ocular Surface Ecosystem (PROSE) for Visual Rehabilitation in Limbal Stem Cell Deficiency
Objectives: To evaluate the clinical outcomes of patients with limbal stem cell deficiency (LSCD) who were fitted with the Prosthetic Replacement of the Ocular Surface Ecosystem (PROSE) scleral device. Methods: In this retrospective, interventional case series, we reviewed the charts of 31 eyes of 19 consecutive patients clinically diagnosed with LSCD who were evaluated for the PROSE device. Clinical data were reviewed before PROSE evaluation and at the last available follow-up. The main outcomes measures were best-corrected distance visual acuity (CDVA) and modified ocular involvement score (OIS), graded using a prev...
Source: Eye and Contact Lens: Science and Clinical Practice - October 28, 2020 Category: Opthalmology Tags: Article Source Type: research

Impact of Changes in the Optical Density of Postlens Fluid on the Clinical Performance of Miniscleral Lenses
Purpose: To determine the impact of optical density changes in postlens fluid on clinical performance and to quantify these changes over time during miniscleral lens wear. Methods: Twenty-three eyes of 13 patients with keratoconus were fitted with a miniscleral lens (scleral Misa lenses; Microlens Contactlens Technology, Arnhem, Netherlands). The lens fit was evaluated using the fluorescein pattern and also through anterior segment optical coherence tomography imaging. The optical density changes were measured using Scheimpflug tomography at 30 min, 1, 2, 3, and 4 hr. High- and low-contrast visual acuity (VA), subject...
Source: Eye and Contact Lens: Science and Clinical Practice - October 28, 2020 Category: Opthalmology Tags: Article Source Type: research

Outcomes of Scleral Contact Lens Use in Veteran Population
Objectives: To document outcomes associated with use of scleral contact lenses (SL) in the veteran population and analyze the medical and demographic factors that affect these outcomes, specifically those involved in contact lens discontinuation. Methods: A retrospective study of consecutive patients first fitted with Jupiter Scleral lenses at the Michael E. DeBakey Veterans Affairs Medical Center between 2010 and 2018. The primary outcome was continuation of SL use at 1 year. Demographic factors and variables such as presence of comorbid diseases, improvement in visual acuity, and daily lens wear time were compared. ...
Source: Eye and Contact Lens: Science and Clinical Practice - October 28, 2020 Category: Opthalmology Tags: Article Source Type: research

Effect of Scleral Lens Wear on Central Corneal Thickness and Intraocular Pressure in Patients With Ocular Surface Disease
Conclusion: There was a statistically significant increase in CCT after scleral lens wear in subjects with ocular surface disease, which may be attributed to subclinical hypoxic conditions created by scleral lens wear. No significant relationship was found between scleral lens wear and IOP. (Source: Eye and Contact Lens: Science and Clinical Practice)
Source: Eye and Contact Lens: Science and Clinical Practice - October 28, 2020 Category: Opthalmology Tags: Article Source Type: research

A Systematic Review of Emerging Therapeutic Strategies in the Management of Chemical Injuries of the Ocular Surface
Conclusion: Recent advances and understanding in various novel therapeutic methods for corneal epithelial chemical injuries should provide potential alternatives to current standard treatment regimens and help reduce risks of complications, hence improve patient outcomes. (Source: Eye and Contact Lens: Science and Clinical Practice)
Source: Eye and Contact Lens: Science and Clinical Practice - October 28, 2020 Category: Opthalmology Tags: Review Article Source Type: research

Contact Lens–Related Microbial Keratitis and Host Genetics
No abstract available (Source: Eye and Contact Lens: Science and Clinical Practice)
Source: Eye and Contact Lens: Science and Clinical Practice - October 28, 2020 Category: Opthalmology Tags: Editorial Source Type: research

A New Perspective on Dry Eye Classification: Proposal by the Asia Dry Eye Society: Erratum
No abstract available (Source: Eye and Contact Lens: Science and Clinical Practice)
Source: Eye and Contact Lens: Science and Clinical Practice - August 25, 2020 Category: Opthalmology Tags: Erratum Source Type: research

Epipremnum aureum Keratopathy: Case Report and Review of the Literature
Conclusion: Epipremnum aureum toxicity is a rare cause of keratitis. It can mimic acanthamoeba keratitis or anesthetic abuse and should be considered in cases of culture negative nonhealing corneal ulcerations. Eliciting a history of plant sap exposure can facilitate appropriate supportive care for this toxic keratitis. (Source: Eye and Contact Lens: Science and Clinical Practice)
Source: Eye and Contact Lens: Science and Clinical Practice - August 25, 2020 Category: Opthalmology Tags: Case Report Source Type: research

Corneal Endotheliitis as a Presentation of Acanthamoeba Keratitis
Conclusions: Corneal endotheliitis, although uncommon, may be a manifestation of AK. We must have high-index suspicion for AK in all contact lens users, particularly before making a diagnosis of HSV keratitis. Accurate diagnosis and prompt treatment can result in a favorable prognosis for AK. (Source: Eye and Contact Lens: Science and Clinical Practice)
Source: Eye and Contact Lens: Science and Clinical Practice - August 25, 2020 Category: Opthalmology Tags: Case Report Source Type: research

Tear Levels of IGFBP-3: A Potential Biomarker for Diabetic Nerve Changes in the Cornea
Conclusions: Overwhelming evidence supports the use of in vivo confocal microscopy as a tool to evaluate corneal nerve and epithelial changes induced by diabetes in research settings. The newly identified relationship between morphological changes in the corneal subbasal nerve plexus in diabetes and the increase in tear levels of IGFBP-3 suggest that this protein may represent an innovative new biomarker to assess risk of ocular and nonocular complications in type 2 diabetes mellitus. (Source: Eye and Contact Lens: Science and Clinical Practice)
Source: Eye and Contact Lens: Science and Clinical Practice - August 25, 2020 Category: Opthalmology Tags: Review Article Source Type: research

Comparative Evaluation of Visual Outcomes After Bilateral Implantation of a Diffractive Trifocal Intraocular Lens and an Extended Depth of Focus Intraocular Lens
Conclusions: Trifocal IOL had a clear advantage over EDOF IOLs in near VA, while both IOLs showed excellent performance in distance and intermediate VA. Both IOLs provided high percentage of spectacle independence and patient satisfaction with minimal level of disturbing photic phenomena. (Source: Eye and Contact Lens: Science and Clinical Practice)
Source: Eye and Contact Lens: Science and Clinical Practice - August 25, 2020 Category: Opthalmology Tags: Article Source Type: research

Additive Effect of Topical Nepafenac on Mydriasis in Patients With Diabetes Mellitus
Conclusions: Nepafenac has been shown additive effect on pupil dilation in diabetic patients before cataract surgery. (Source: Eye and Contact Lens: Science and Clinical Practice)
Source: Eye and Contact Lens: Science and Clinical Practice - August 25, 2020 Category: Opthalmology Tags: Article Source Type: research

Corneal Biomechanical Evaluation After Conventional Corneal Crosslinking With Oxygen Enrichment
Purpose: To assess corneal biomechanical changes after conventional corneal crosslinking (CXL), with and without oxygen enrichment. Methods: Sixty fresh porcine corneas were randomly divided into group 1 (control), group 2 (conventional CXL), and group 3 (conventional CXL in a high-oxygen environment during ultraviolet A [UVA] irradiation). After crosslinking, a 5-mm wide corneal strip was extracted using a double-bladed knife from 12 to 6'o clock. The Young's modulus of each strip was determined by stress–strain measurements. A comparison between the three groups was performed with a one-way analysis of variance. ...
Source: Eye and Contact Lens: Science and Clinical Practice - August 25, 2020 Category: Opthalmology Tags: Article Source Type: research

Changing Indications for Corneal Transplantations in Southern Taiwan From 2008 to 2018
Conclusion: The indications for corneal transplantations changed with time in Taiwan. Regraft was the leading indication, but there was a decreasing trend over time. The proportion of bullous keratopathy increased significantly over the past decade and is the second most common indication, similar to the most developed countries. Both corneal scar and opacity, and keratitis showed a decreasing trend of occurrence compared with a previous study in Taiwan. The proportion of keratoconus remained low, making it the least common indication for corneal transplantation. (Source: Eye and Contact Lens: Science and Clinical Practice)
Source: Eye and Contact Lens: Science and Clinical Practice - August 25, 2020 Category: Opthalmology Tags: Article Source Type: research

Comparison of Biomicroscopy and Light Microscopy Findings in Demodex Diagnosis in Patients With Chronic Blepharitis
Conclusions: Careful biomicroscopic examination can be time-efficient and cost-effective, and the need for more advanced and invasive procedures for the identification of Demodex in patients with chronic blepharitis can be reduced. (Source: Eye and Contact Lens: Science and Clinical Practice)
Source: Eye and Contact Lens: Science and Clinical Practice - August 25, 2020 Category: Opthalmology Tags: Article Source Type: research