Miniscleral Contact Lens in Pediatric Age Group: Indications, Safety, and Efficacy
Objective: To report indications, fitting feasibility, and safety of miniscleral design (MSD) lenses in children. Methods: Medical records of patients aged (Source: Eye and Contact Lens: Science and Clinical Practice)
Source: Eye and Contact Lens: Science and Clinical Practice - June 24, 2021 Category: Opthalmology Tags: Article Source Type: research

Irregular Astigmatism Management Using SPOT Scleral Lenses in the Treatment of Corneal Ectasia and Penetrating Keratoplasty
Conclusion: SPOT scleral contact lenses are an effective and well tolerated method to improve the VA of patients with irregular astigmatism. (Source: Eye and Contact Lens: Science and Clinical Practice)
Source: Eye and Contact Lens: Science and Clinical Practice - June 24, 2021 Category: Opthalmology Tags: Article Source Type: research

Diagnoses and Outcomes of Prosthetic Replacement of the Ocular Surface Ecosystem Treatment—A Canadian Experience
Objectives: To investigate underlying diagnoses and outcomes of patients undergoing Prosthetic Replacement of the Ocular Surface Ecosystem (PROSE) treatment at the first Canadian PROSE center. Methods: A retrospective chart review was conducted on patients referred for PROSE treatment and fitted with PROSE devices from 2018 to 2020. Data were collected on diagnoses, presenting symptoms, previous lens modalities attempted, best-corrected visual acuities (BCVAs) pre-PROSE and post-PROSE, daily wear time, and failure rates. Best-corrected visual acuities pre-PROSE and post-PROSE were compared to evaluate visual imp...
Source: Eye and Contact Lens: Science and Clinical Practice - June 24, 2021 Category: Opthalmology Tags: Article Source Type: research

Lysozyme Deposition on Contact Lenses in an In Vitro Blink-Simulation Eye Model Versus a Static Vial Deposition Model
Purpose: To evaluate active lysozyme deposition on daily disposable (DD) contact lenses (CL) using a novel in vitro blink model. Methods: Three conventional hydrogel DD CL materials (etafilcon A, omafilcon A, nelfilcon A) and three silicone hydrogel DD CL materials (delefilcon A, senofilcon A, somofilcon A) were tested. The device blink rate was set to 6 blinks/min with a tear flow rate of 1 μL/min using an artificial tear solution (ATS) containing lysozyme and other typical tear film components. After incubation at 2, 4, or 8 hr, lenses were removed, and lysozyme activity was measured. A separate experiment wa...
Source: Eye and Contact Lens: Science and Clinical Practice - June 24, 2021 Category: Opthalmology Tags: Article Source Type: research

Use of Soft Contact Lens for Esthetic and Functional Rehabilitation
Conclusion: Colored SCLs can cover ocular surface imperfections in VI or blind eyes of patients who are seeking better cosmesis or improvement functional VI. Soft contact lenses with only one filter can cover imperfections of the ocular surface and improve vision in functional VI. Appropriate follow-up of these patients can reduce complication rates, resulting in good cosmesis and patient satisfaction with a positive impact on the lives of patients suffering from functional VI or blindness. (Source: Eye and Contact Lens: Science and Clinical Practice)
Source: Eye and Contact Lens: Science and Clinical Practice - June 24, 2021 Category: Opthalmology Tags: Review Article Source Type: research

Interface Fluid Syndrome 2 Decades After Laser-Assisted In situ Keratomileusis
Conclusions: Even decades later, IFS should be considered as a source of corneal edema in patients after LASIK. Monitoring these patients with AS-OCT is recommended. (Source: Eye and Contact Lens: Science and Clinical Practice)
Source: Eye and Contact Lens: Science and Clinical Practice - May 27, 2021 Category: Opthalmology Tags: Case Report Source Type: research

Anterior Segment Ischemia After Peripheral Annular Lamellar Sclerokeratoplasty for Advanced Terrien Marginal Degeneration
Abstract: A man with 360° bilateral peripheral thinning, peripheral vascularization, and lipid deposition diagnosed with Terrien marginal degeneration, underwent a 360° peripheral annular lamellar sclerokeratoplasty (PALK) (tuck-in) in the right eye for 90% peripheral thinning and high astigmatism. One-week postoperatively, a sudden drop in vision to counting fingers 1 m from 20/50 with circumciliary congestion, diffuse corneal edema, intense anterior chamber inflammation, keratic precipitates with fixed dilated pupil, and hypotony led to a diagnosis of suspected anterior segment ischemia. Anterior segment fluorescei...
Source: Eye and Contact Lens: Science and Clinical Practice - May 27, 2021 Category: Opthalmology Tags: Case Report Source Type: research

TNF-α Inhibitors for the Management of Intractable Corneal Melt: Report of Three Cases and Review of the Literature
Conclusions: Inhibiting TNF-α-mediated expression of matrix metalloproteinases responsible for collagen breakdown should be considered in refractory cases, as a means of globe salvage. (Source: Eye and Contact Lens: Science and Clinical Practice)
Source: Eye and Contact Lens: Science and Clinical Practice - May 27, 2021 Category: Opthalmology Tags: Article Source Type: research

Remodeling of Cornea With Isotretinoin Treatment
Objectives: To evaluate the change of corneal epithelial thickness (ET) in subjects using isotretinoin with spectral-domain optical coherence tomography and further to explore reflection of changes on corneal topography. Methods: Forty eyes of 40 subjects with acne vulgaris scheduled for oral isotretinoin were included in this prospective study. Subjects were examined with RTVue-XR and Pentacam at baseline, 1th, 3rd, and 6th months of treatment, and 3rd month of isotretinoin cessation. Results: A statistically significant increase was detected in each sector of ET map except inferonasal 7 to 9 mm between ...
Source: Eye and Contact Lens: Science and Clinical Practice - May 27, 2021 Category: Opthalmology Tags: Article Source Type: research

Corneal Changes After Belantamab Mafodotin in Multiple Myeloma Patients
Conclusion: We describe MECs and LSCD associated with systemic administration of belamaf. Further study is needed to determine the etiology and composition of the MECs and the mechanism of limbal stem cell involvement. (Source: Eye and Contact Lens: Science and Clinical Practice)
Source: Eye and Contact Lens: Science and Clinical Practice - May 27, 2021 Category: Opthalmology Tags: Article Source Type: research

Optimization of Contact Lenses for Corneal Protection During Vitreoretinal Surgery
Conclusion: The XO lens offers better corneal protection during noncontact wide-angle vitreoretinal surgery and protects the corneal epithelium more efficiently during vitrectomy in patients with PDR, irrespective of its thickness. (Source: Eye and Contact Lens: Science and Clinical Practice)
Source: Eye and Contact Lens: Science and Clinical Practice - May 27, 2021 Category: Opthalmology Tags: Article Source Type: research

Novel Method to Determine Target Refraction in Cataract Surgery for Patients Dependent on Therapeutic Scleral Lenses
Conclusions: Using this method, patients requiring therapeutic scleral lenses can quickly experience optimal vision, comfort, and ocular surface protection 1 week after cataract surgery. These patients can continue to use their existing scleral lenses and avoid the costs and burdens associated with lens replacement. (Source: Eye and Contact Lens: Science and Clinical Practice)
Source: Eye and Contact Lens: Science and Clinical Practice - May 27, 2021 Category: Opthalmology Tags: Article Source Type: research

Quantifying the Effect of Spectacle Frame Dimensions on Wind-Induced Ocular Plane Evaporation Using an in Vitro Model
Purpose: To quantify the effect of spectacle frame dimensions on wind-induced ocular plane evaporation. Methods: A drop of 0.5 μL water was pipetted onto an eye of a mannequin head. The face was fitted with a spectacle frame. A fan positioned 10 cm away directed air (185 CFM) toward the face and the time required for the drop to evaporate was recorded. This procedure was repeated with 31 different frames to obtain evaporation times for various eye sizes, vertical heights, vertex distances, temperature, and humidity. This was also repeated 30 times without spectacle wear to obtain evaporation times for various t...
Source: Eye and Contact Lens: Science and Clinical Practice - May 27, 2021 Category: Opthalmology Tags: Article Source Type: research

Measurement of the Lower Lid Margin Thickness by Oculus Keratograph
Objectives: To investigate the lower lid margin thickness (LLMT) from the posterior lash line to the anterior edge of tear meniscus with Oculus Keratograph 4 (K4). Methods: This was a prospective, single-center, observational study. A total of 90 volunteers aged 18 to 79 years with no ocular diseases were included in this study. The LLMT of 90 subjects was measured twice by the same person with K4. To determine the reliability of K4, measuring the LLMT of 30 normal subjects was separately performed by two operators. Results: The LLMT measurements with K4 between two operators demonstrated a good reproduci...
Source: Eye and Contact Lens: Science and Clinical Practice - May 27, 2021 Category: Opthalmology Tags: Article Source Type: research

Comparative Study of Two Infrared Meibographers in Evaporative Dry Eye Versus Nondry Eye Patients
Conclusions: Statistically significant differences in the MG dropout percentage in the upper eyelid of nondry eye patients were obtained from both meibographers. The measurements were similar in patients with dry eye, suggesting that the two instruments can be interchanged. (Source: Eye and Contact Lens: Science and Clinical Practice)
Source: Eye and Contact Lens: Science and Clinical Practice - May 27, 2021 Category: Opthalmology Tags: Article Source Type: research