Expert Review of Gastroenterology and Hepatology This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Recommendations for the management of opioid-induced constipation - how to improve usability in clinical practice
This article introduces the concept of opioid-induced constipation and provides an overview of existing guidelines in this field. We also propose simplified recommendations for managing opioid-induced constipation, derived from a synthesis of current guidelines and the principles of optimal guideline design theory.EXPERT OPINION: Despite standard treatment with laxatives and fluid intake in patients with opioid-induced constipation, escalation of treatment is often needed where μ-opioid receptor antagonists or newer medications such as lubiprostone, linaclotide, or prucalopride are used. Previous guidelines have not been ...
Source: Expert Review of Gastroenterology and Hepatology - October 12, 2023 Category: Gastroenterology Authors: Tina Okdahl Anton Emmanuel Bart Morlion Adam Farmer Giustino Varrassi Asbj ørn Mohr Drewes Source Type: research

The role of microRnas in the different phases of liver regeneration
Expert Rev Gastroenterol Hepatol. 2023 Oct 9. doi: 10.1080/17474124.2023.2267422. Online ahead of print.ABSTRACTINTRODUCTION: Since the first discovery of microRNAs (miRs) extensive evidence reveals their indispensable role in different patho-physiological processes. They are recognized as critical regulators of hepatic regeneration, as they modulate multiple complex signaling pathways affecting liver regeneration. MiR-related translational suppression and degradation of target mRNAs and proteins are not limited to one specific gene, but act on multiple targets.AREAS COVERED: In this review, we are going to explore the rol...
Source: Expert Review of Gastroenterology and Hepatology - October 9, 2023 Category: Gastroenterology Authors: Anna Emilia Kern Gregor Ortmayr Alice Assinger Patrick Starlinger Source Type: research

Relief from behind: enemas, the back door enforcement to help treating chronic constipation in adults
Expert Rev Gastroenterol Hepatol. 2023 Oct 7. doi: 10.1080/17474124.2023.2267968. Online ahead of print.ABSTRACTINTRODUCTION: Chronic constipation is a frequent symptom encountered in the daily clinical practice. The treatment of this condition mainly relies on the use of laxatives. However, patients' satisfaction with this approach is limited, and alternative measures are often added to the treatment. Among these, particularly frequent worldwide is the use of enemas, even though literature data on its scientific validity are scarce.AREAS COVERED: In this article, by an extensive online search of Medline (through PubMed), ...
Source: Expert Review of Gastroenterology and Hepatology - October 7, 2023 Category: Gastroenterology Authors: Gabrio Bassotti Source Type: research

Towards a better diagnosis of gastro-esophageal reflux disease
Expert Rev Gastroenterol Hepatol. 2023 Oct 6. doi: 10.1080/17474124.2023.2267435. Online ahead of print.ABSTRACTINTRODUCTION: GERD is a common disorder and is characterized by the presence of typical or atypical symptoms. In GERD patients, presence of mucosal alterations at endoscopy are detected in up to 30% of individuals. The clinical presentation of GERD patients may be complex and their management is challenging, due to the heterogeneous clinical presentation. The present review has been performed searching all relevant articles in this field, over the past years, using PubMed database.AREAS COVERED: The diagnosis and...
Source: Expert Review of Gastroenterology and Hepatology - October 6, 2023 Category: Gastroenterology Authors: Mentore Ribolsi Edoardo Savarino Source Type: research

Managing pediatric Crohn's disease: recent insights
Expert Rev Gastroenterol Hepatol. 2023 Oct 4. doi: 10.1080/17474124.2023.2267431. Online ahead of print.ABSTRACTINTRODUCTION: Children and adolescents with Crohn's disease present unique challenges due to extensive disease at diagnosis and the effect of bowel inflammation on growth. Historical approaches with corticosteroids and immunomodulators are far less effective than early treatment with anti-TNF biologics.AREAS COVERED: This review covers recent literature delineating the crucial role of early anti-TNF therapy in the treatment of moderate- to- severe Crohn's disease in children and adolescents. The potential risks a...
Source: Expert Review of Gastroenterology and Hepatology - October 5, 2023 Category: Gastroenterology Authors: Katherine Baldwin Victoria Grossi Jeffrey S Hyams Source Type: research

Efficacy and safety of Tolvaptan in cirrhotic patients: a systematic review and meta-analysis of randomized controlled trials
CONCLUSION: Short-term use of tolvaptan may be considered in cirrhotic patients with ascites who have inadequate response to conventional diuretics and those with hyponatremia.PMID:37794713 | DOI:10.1080/17474124.2023.2267421 (Source: Expert Review of Gastroenterology and Hepatology)
Source: Expert Review of Gastroenterology and Hepatology - October 5, 2023 Category: Gastroenterology Authors: Lu Chai Zhe Li Ting Wang Ran Wang Kanokwan Pinyopornpanish Gang Cheng Xingshun Qi Source Type: research

The necessity and safety of simultaneous cholecystectomy during gastric surgery for patients with asymptomatic cholelithiasis
CONCLUSIONS: Simultaneous cholecystectomy is both necessary and safe for patients with asymptomatic cholelithiasis undergoing gastric surgery. It is crucial to assess the gallbladder's condition before gastric surgery, and if the gallbladder status is unknown, simultaneous cholecystectomy should be avoided.PMID:37795528 | DOI:10.1080/17474124.2023.2264782 (Source: Expert Review of Gastroenterology and Hepatology)
Source: Expert Review of Gastroenterology and Hepatology - October 5, 2023 Category: Gastroenterology Authors: Tianxiang Jiang Haidong Zhang Xiaonan Yin Zhaolun Cai Zhou Zhao Mingchun Mu Baike Liu Chaoyong Shen Bo Zhang Yuan Yin Source Type: research