In vivo near-infrared fluorescent optical imaging for CNS drug discovery
. (Source: Expert Opinion on Drug Discovery)
Source: Expert Opinion on Drug Discovery - May 11, 2020 Category: Drugs & Pharmacology Authors: Maria J. Moreno Binbing Ling Danica B. Stanimirovic Source Type: research

Current models of pulmonary fibrosis for future drug discovery efforts
. (Source: Expert Opinion on Drug Discovery)
Source: Expert Opinion on Drug Discovery - May 11, 2020 Category: Drugs & Pharmacology Authors: Toyoshi Yanagihara Sy Giin Chong Megan Vierhout Jeremy A. Hirota Kjetil Ask Martin Kolb Source Type: research

Porcine cancer models: potential tools to enhance cancer drug trials
. (Source: Expert Opinion on Drug Discovery)
Source: Expert Opinion on Drug Discovery - May 6, 2020 Category: Drugs & Pharmacology Authors: Noah Robertson Lawrence B. Schook Kyle M. Schachtschneider Source Type: research

High-throughput screening in multicellular spheroids for target discovery in the tumor microenvironment
. (Source: Expert Opinion on Drug Discovery)
Source: Expert Opinion on Drug Discovery - May 3, 2020 Category: Drugs & Pharmacology Authors: Blaise Calpe Werner J. Kovacs Source Type: research

Advances of droplet-based microfluidics in drug discovery
. (Source: Expert Opinion on Drug Discovery)
Source: Expert Opinion on Drug Discovery - April 29, 2020 Category: Drugs & Pharmacology Authors: Yuetong Wang Zhuoyue Chen Feika Bian Luoran Shang Kaixuan Zhu Yuanjin Zhao Source Type: research

The emerging role of computational design in peptide macrocycle drug discovery
. (Source: Expert Opinion on Drug Discovery)
Source: Expert Opinion on Drug Discovery - April 28, 2020 Category: Drugs & Pharmacology Authors: Vikram K. Mulligan Source Type: research

Is high performance computing a requirement for novel drug discovery and how will this impact academic efforts?
. (Source: Expert Opinion on Drug Discovery)
Source: Expert Opinion on Drug Discovery - April 28, 2020 Category: Drugs & Pharmacology Authors: Sav íns Puertas-Martín Antonio J. Banegas-Luna Mar ía Paredes-Ramos Juana L. Redondo Pilar M. Ortigosa Ol ’Ha O. Brovarets' Horacio P érez-Sánchez Source Type: research

Novel approaches and current challenges with targeting the endocannabinoid system
. (Source: Expert Opinion on Drug Discovery)
Source: Expert Opinion on Drug Discovery - April 26, 2020 Category: Drugs & Pharmacology Authors: Paula Morales Nadine Jagerovic Source Type: research

Recent approaches to gout drug discovery: an update
. (Source: Expert Opinion on Drug Discovery)
Source: Expert Opinion on Drug Discovery - April 23, 2020 Category: Drugs & Pharmacology Authors: Naoyuki Otani Motoshi Ouchi Hideo Kudo Shuichi Tsuruoka Ichiro Hisatome Naohiko Anzai Source Type: research

Advances in the discovery of fatty acid amide hydrolase inhibitors: what does the future hold?
. (Source: Expert Opinion on Drug Discovery)
Source: Expert Opinion on Drug Discovery - April 14, 2020 Category: Drugs & Pharmacology Authors: Domenico Fazio Emanuele Criscuolo Alessandra Piccoli Barbara Barboni Filomena Fezza Mauro Maccarrone Source Type: research

The preclinical discovery and development of the combination of ivacaftor + tezacaftor used to treat cystic fibrosis
. (Source: Expert Opinion on Drug Discovery)
Source: Expert Opinion on Drug Discovery - April 14, 2020 Category: Drugs & Pharmacology Authors: Lorenzo Guerra Maria Favia Sante Di Gioia Onofrio Laselva Arianna Bisogno Valeria Casavola Carla Colombo Massimo Conese Source Type: research

Nanonization techniques to overcome poor water-solubility with drugs
. (Source: Expert Opinion on Drug Discovery)
Source: Expert Opinion on Drug Discovery - April 14, 2020 Category: Drugs & Pharmacology Authors: Fl ávia Lidiane Oliveira Da Silva Maria Bet ânia De Freitas Marques Kelly Cristina Kato Guilherme Carneiro Source Type: research

Recent developments and strategies for the discovery of TACE inhibitors
. (Source: Expert Opinion on Drug Discovery)
Source: Expert Opinion on Drug Discovery - April 12, 2020 Category: Drugs & Pharmacology Authors: Prashant R. Murumkar Rahul B. Ghuge Monica Chauhan Rahul R. Barot Sharmishtha Sorathiya Kailash M. Choudhary Karan D. Joshi Mange Ram Yadav Source Type: research

Targeting the Wnt/ β-catenin pathway in neurodegenerative diseases: recent approaches and current challenges
. (Source: Expert Opinion on Drug Discovery)
Source: Expert Opinion on Drug Discovery - April 12, 2020 Category: Drugs & Pharmacology Authors: Annalucia Serafino Daniela Giovannini Simona Rossi Mauro Cozzolino Source Type: research

The impact of crowdsourcing in modern drug discovery
. (Source: Expert Opinion on Drug Discovery)
Source: Expert Opinion on Drug Discovery - April 6, 2020 Category: Drugs & Pharmacology Authors: Alexander Schuhmacher Michael Kuss Source Type: research

The discovery and development of binimetinib for the treatment of melanoma
. (Source: Expert Opinion on Drug Discovery)
Source: Expert Opinion on Drug Discovery - April 3, 2020 Category: Drugs & Pharmacology Authors: Brian Tran Mark S. Cohen Source Type: research

Surface plasmon resonance, Orbitrap mass spectrometry and Raman advancements: exciting new techniques in drug discovery
. (Source: Expert Opinion on Drug Discovery)
Source: Expert Opinion on Drug Discovery - March 30, 2020 Category: Drugs & Pharmacology Authors: Gopal P. Jadhav Pavan Kumar Prathipati Harsh Chauhan Source Type: research

Synthetic lethality on drug discovery: an update on cancer therapy
. (Source: Expert Opinion on Drug Discovery)
Source: Expert Opinion on Drug Discovery - March 30, 2020 Category: Drugs & Pharmacology Authors: M. Shahar Yar Kashif Haider Vivek Gohel Nasir Ali Siddiqui Ahmed Kamal Source Type: research

Approaches for designing and discovering purinergic drugs for gastrointestinal diseases
. (Source: Expert Opinion on Drug Discovery)
Source: Expert Opinion on Drug Discovery - March 30, 2020 Category: Drugs & Pharmacology Authors: Diego Dal Ben Luca Antonioli Catia Lambertucci Andrea Spinaci Matteo Fornai Vanessa D ’Antongiovanni Carolina Pellegrini Corrado Blandizzi Rosaria Volpini Source Type: research

The power of deep learning to ligand-based novel drug discovery
. (Source: Expert Opinion on Drug Discovery)
Source: Expert Opinion on Drug Discovery - March 30, 2020 Category: Drugs & Pharmacology Authors: Igor I. Baskin Source Type: research

The roles of human induced pluripotent stem cell-derived cardiomyocytes in drug discovery: managing in vitro safety study expectations
. (Source: Expert Opinion on Drug Discovery)
Source: Expert Opinion on Drug Discovery - March 26, 2020 Category: Drugs & Pharmacology Authors: Gary Gintant Martin Traebert Source Type: research

Exploring the multiple binding modes of inhibitors to carbonic anhydrases for novel drug discovery
. (Source: Expert Opinion on Drug Discovery)
Source: Expert Opinion on Drug Discovery - March 24, 2020 Category: Drugs & Pharmacology Authors: Claudiu T. Supuran Source Type: research

The preclinical discovery and development of oral miltefosine for the treatment of visceral leishmaniasis: a case history
. (Source: Expert Opinion on Drug Discovery)
Source: Expert Opinion on Drug Discovery - March 22, 2020 Category: Drugs & Pharmacology Authors: Juliana Q. Reim ão D ébora P. Pita Pedro Adriano C. Coelho Source Type: research

Harnessing the power of microscopy images to accelerate drug discovery: what are the possibilities?
. (Source: Expert Opinion on Drug Discovery)
Source: Expert Opinion on Drug Discovery - March 20, 2020 Category: Drugs & Pharmacology Authors: Justin Boyd Myles Fennell Anne Carpenter Source Type: research

Fluorinated scaffolds for antimalarial drug discovery
. (Source: Expert Opinion on Drug Discovery)
Source: Expert Opinion on Drug Discovery - March 20, 2020 Category: Drugs & Pharmacology Authors: Charu Upadhyay Monika Chaudhary Ronaldo N. De Oliveira Aniko Borbas Prakasha Kempaiah Poonam Brijesh Rathi Source Type: research

How can preclinical cognitive research further neuropsychiatric drug discovery? Chances and challenges
. (Source: Expert Opinion on Drug Discovery)
Source: Expert Opinion on Drug Discovery - March 17, 2020 Category: Drugs & Pharmacology Authors: Istv án Gyertyán Source Type: research

Predictive modeling for cancer drug discovery using canine models
. (Source: Expert Opinion on Drug Discovery)
Source: Expert Opinion on Drug Discovery - March 15, 2020 Category: Drugs & Pharmacology Authors: Michael D. Lucroy Mark A. Suckow Source Type: research

Partnerships for better neglected disease drug discovery and development: how have we fared?
. (Source: Expert Opinion on Drug Discovery)
Source: Expert Opinion on Drug Discovery - March 9, 2020 Category: Drugs & Pharmacology Authors: Temmy Sunyoto Source Type: research

Advances in cell-based permeability assays to screen drugs for intestinal absorption
. (Source: Expert Opinion on Drug Discovery)
Source: Expert Opinion on Drug Discovery - March 9, 2020 Category: Drugs & Pharmacology Authors: Donna A. Volpe Source Type: research

Lichenochemicals: extraction, purification, characterization, and application as potential anticancer agents
. (Source: Expert Opinion on Drug Discovery)
Source: Expert Opinion on Drug Discovery - March 9, 2020 Category: Drugs & Pharmacology Authors: Mahshid Mohammadi Vasudeo Zambare Ladislav Malek Christine Gottardo Zacharias Suntres Lew Christopher Source Type: research

Targeting macrophages: a novel avenue for cancer drug discovery
. (Source: Expert Opinion on Drug Discovery)
Source: Expert Opinion on Drug Discovery - March 5, 2020 Category: Drugs & Pharmacology Authors: Sahana Kumar Anujan Ramesh Ashish Kulkarni Source Type: research

Can we mimic skeletal muscles for novel drug discovery?
. (Source: Expert Opinion on Drug Discovery)
Source: Expert Opinion on Drug Discovery - March 2, 2020 Category: Drugs & Pharmacology Authors: Torie Broer Alastair Khodabukus Nenad Bursac Source Type: research

How do we improve histone deacetylase inhibitor drug discovery?
. (Source: Expert Opinion on Drug Discovery)
Source: Expert Opinion on Drug Discovery - March 1, 2020 Category: Drugs & Pharmacology Authors: Abdallah Hamze Source Type: research

An overview of spirooxindole as a promising scaffold for novel drug discovery
. (Source: Expert Opinion on Drug Discovery)
Source: Expert Opinion on Drug Discovery - February 27, 2020 Category: Drugs & Pharmacology Authors: Li-Ming Zhou Ren-Yu Qu Guang-Fu Yang Source Type: research

Discovery of drugs that directly target the intrinsically disordered region of the androgen receptor
. (Source: Expert Opinion on Drug Discovery)
Source: Expert Opinion on Drug Discovery - February 25, 2020 Category: Drugs & Pharmacology Authors: Marianne D. Sadar Source Type: research

How do we optimize chemical space navigation?
. (Source: Expert Opinion on Drug Discovery)
Source: Expert Opinion on Drug Discovery - February 17, 2020 Category: Drugs & Pharmacology Authors: Martin Vogt Source Type: research

Strategies for targeting the cardiac sarcomere: avenues for novel drug discovery
. (Source: Expert Opinion on Drug Discovery)
Source: Expert Opinion on Drug Discovery - February 17, 2020 Category: Drugs & Pharmacology Authors: Joshua B. Holmes Chang Yoon Doh Ranganath Mamidi Jiayang Li Julian E. Stelzer Source Type: research

An interview with Dr Tanya Parish and her perspectives on women in drug discovery
. (Source: Expert Opinion on Drug Discovery)
Source: Expert Opinion on Drug Discovery - February 17, 2020 Category: Drugs & Pharmacology Authors: Tanya Parish David Grech Source Type: research

How can we better realize the potential of immobilized artificial membrane chromatography in drug discovery and development?
. (Source: Expert Opinion on Drug Discovery)
Source: Expert Opinion on Drug Discovery - February 17, 2020 Category: Drugs & Pharmacology Authors: Anna Tsantili-Kakoulidou Source Type: research

Promising models for cancer-induced cachexia drug discovery
. (Source: Expert Opinion on Drug Discovery)
Source: Expert Opinion on Drug Discovery - February 12, 2020 Category: Drugs & Pharmacology Authors: Tsuyoshi Suzuki Stephan Von Haehling Jochen Springer Source Type: research

An overview of drug discovery efforts for eczema: why is this itch so difficult to scratch?
. (Source: Expert Opinion on Drug Discovery)
Source: Expert Opinion on Drug Discovery - February 12, 2020 Category: Drugs & Pharmacology Authors: Kam Lun Hon Steven Loo Alexander K. C. Leung Joyce T. S. Li Vivian W. Y. Lee Source Type: research

What translatable knowledge from dengue vaccine design can we pass onto future anti-parasitic vaccine development?
. (Source: Expert Opinion on Drug Discovery)
Source: Expert Opinion on Drug Discovery - February 10, 2020 Category: Drugs & Pharmacology Authors: Anon Srikiatkhachorn Source Type: research

Modulators of calpain activity: inhibitors and activators as potential drugs
. (Source: Expert Opinion on Drug Discovery)
Source: Expert Opinion on Drug Discovery - February 6, 2020 Category: Drugs & Pharmacology Authors: Levente Endre D ókus Mo ’ath Yousef Zolt án Bánóczi Source Type: research

Metabolomic tools used in marine natural product drug discovery
. (Source: Expert Opinion on Drug Discovery)
Source: Expert Opinion on Drug Discovery - February 6, 2020 Category: Drugs & Pharmacology Authors: Kevin Andrew Stuart Keira Welsh Molly Clare Walker RuAngelie Edrada-Ebel Source Type: research

Foreword: Women in Drug Discovery
. (Source: Expert Opinion on Drug Discovery)
Source: Expert Opinion on Drug Discovery - February 5, 2020 Category: Drugs & Pharmacology Authors: David Grech Source Type: research

New avenues for therapeutic discovery against West Nile virus
. (Source: Expert Opinion on Drug Discovery)
Source: Expert Opinion on Drug Discovery - February 5, 2020 Category: Drugs & Pharmacology Authors: Alessandro Sinigaglia Elektra Peta Silvia Riccetti Luisa Barzon Source Type: research

Duchenne muscular dystrophy animal models for high-throughput drug discovery and precision medicine
. (Source: Expert Opinion on Drug Discovery)
Source: Expert Opinion on Drug Discovery - January 31, 2020 Category: Drugs & Pharmacology Authors: Nalinda B. Wasala Shi-Jie Chen Dongsheng Duan Source Type: research

The impact of chemoinformatics on drug discovery in the pharmaceutical industry
. (Source: Expert Opinion on Drug Discovery)
Source: Expert Opinion on Drug Discovery - January 25, 2020 Category: Drugs & Pharmacology Authors: Karina Martinez-Mayorga Abraham Madariaga-Mazon Jos é L. Medina-Franco Gerald Maggiora Source Type: research

Preclinical discovery and development of evolocumab for the treatment of hypercholesterolemia
. (Source: Expert Opinion on Drug Discovery)
Source: Expert Opinion on Drug Discovery - January 25, 2020 Category: Drugs & Pharmacology Authors: Etienne Khoury Diane Brisson Daniel Gaudet Source Type: research