Targeting the BAF complex in advanced prostate cancer
. (Source: Expert Opinion on Drug Discovery)
Source: Expert Opinion on Drug Discovery - September 16, 2020 Category: Drugs & Pharmacology Authors: Andrew Hartley Hing Y. Leung Imran Ahmad Source Type: research

Animal models for the discovery of novel drugs for post-traumatic stress disorder
. (Source: Expert Opinion on Drug Discovery)
Source: Expert Opinion on Drug Discovery - September 14, 2020 Category: Drugs & Pharmacology Authors: Phillip R. Zoladz Source Type: research

Challenges with matrix metalloproteinase inhibition and future drug discovery avenues
. (Source: Expert Opinion on Drug Discovery)
Source: Expert Opinion on Drug Discovery - September 14, 2020 Category: Drugs & Pharmacology Authors: Thomas Fischer Rainer Riedl Source Type: research

How not to discover a drug - integrins
. (Source: Expert Opinion on Drug Discovery)
Source: Expert Opinion on Drug Discovery - September 14, 2020 Category: Drugs & Pharmacology Authors: Dermot Cox Source Type: research

The preclinical discovery and development of rectal artesunate for the treatment of malaria in young children; review of evidence
. (Source: Expert Opinion on Drug Discovery)
Source: Expert Opinion on Drug Discovery - September 14, 2020 Category: Drugs & Pharmacology Authors: La ís Pessanha de Carvalho Andrea Kreidenweiss Jana Held Source Type: research

Are open-source approaches the most efficient way forward for COVID-19 drug discovery?
. (Source: Expert Opinion on Drug Discovery)
Source: Expert Opinion on Drug Discovery - September 11, 2020 Category: Drugs & Pharmacology Authors: Amer Harky Vaibhav Mishra Daniyal Matin Ansari Naomi Melamed Source Type: research

Metallo therapeutics for COVID-19. Exploiting metal-based compounds for the discovery of new antiviral drugs
. (Source: Expert Opinion on Drug Discovery)
Source: Expert Opinion on Drug Discovery - September 11, 2020 Category: Drugs & Pharmacology Authors: Damiano Cirri Alessandro Pratesi Tiziano Marzo Luigi Messori Source Type: research

Multi-targeted drug design strategies for the treatment of schizophrenia
. (Source: Expert Opinion on Drug Discovery)
Source: Expert Opinion on Drug Discovery - September 11, 2020 Category: Drugs & Pharmacology Authors: Piotr St ępnicki Magda Kondej Oliwia Kosz ła Justyna Żuk Agnieszka A. Kaczor Source Type: research

What are the practical, ethical, and pathobiological considerations in the use of minipigs as an animal model in drug discovery for acute radiation syndrome and delayed effects of acute radiation exposure?
. (Source: Expert Opinion on Drug Discovery)
Source: Expert Opinion on Drug Discovery - September 7, 2020 Category: Drugs & Pharmacology Authors: Doreswamy Kenchegowda Thomas M. Seed Vijay K. Singh Source Type: research

Phenotypic screening techniques for Cryptosporidium drug discovery
. (Source: Expert Opinion on Drug Discovery)
Source: Expert Opinion on Drug Discovery - September 7, 2020 Category: Drugs & Pharmacology Authors: Melissa S. Love Case W. McNamara Source Type: research

Novel therapeutic strategies for treating Pseudomonas aeruginosa infection
. (Source: Expert Opinion on Drug Discovery)
Source: Expert Opinion on Drug Discovery - September 3, 2020 Category: Drugs & Pharmacology Authors: Xiaolong Shao Yingpeng Xie Yingchao Zhang Jingui Liu Yiqing Ding Min Wu Xin Wang Xin Deng Source Type: research

A public-private partnership for the express development of antiviral leads: a perspective view
. (Source: Expert Opinion on Drug Discovery)
Source: Expert Opinion on Drug Discovery - September 2, 2020 Category: Drugs & Pharmacology Authors: Anatoly Mayburd Source Type: research

Combining therapeutic vaccines with chemo- and immunotherapies in the treatment of cancer
. (Source: Expert Opinion on Drug Discovery)
Source: Expert Opinion on Drug Discovery - September 1, 2020 Category: Drugs & Pharmacology Authors: Matthew D. Kerr David A. McBride Arun K. Chumber Nisarg J. Shah Source Type: research

Pharmacological strategies to overcome treatment resistance in acute myeloid leukemia: increasing leukemic drug exposure by targeting the resistance factor SAMHD1 and the toxicity factor Top2 β
. (Source: Expert Opinion on Drug Discovery)
Source: Expert Opinion on Drug Discovery - August 31, 2020 Category: Drugs & Pharmacology Authors: Nikolas Herold Source Type: research

An update on dengue vaccine development, challenges, and future perspectives
. (Source: Expert Opinion on Drug Discovery)
Source: Expert Opinion on Drug Discovery - August 25, 2020 Category: Drugs & Pharmacology Authors: Fakhriedzwan Idris Donald Heng Rong Ting Sylvie Alonso Source Type: research

Drug development for noise-induced hearing loss
. (Source: Expert Opinion on Drug Discovery)
Source: Expert Opinion on Drug Discovery - August 25, 2020 Category: Drugs & Pharmacology Authors: Isabel Varela-Nieto Silvia Murillo-Cuesta Miryam Calvino Rafael Cediel Luis Lassaletta Source Type: research

Animal models of Chagas disease and their translational value to drug development
. (Source: Expert Opinion on Drug Discovery)
Source: Expert Opinion on Drug Discovery - August 19, 2020 Category: Drugs & Pharmacology Authors: Eric Chatelain Ivan Scandale Source Type: research

Evolution of chromone-like compounds as potential antileishmanial agents, through the 21st century
. (Source: Expert Opinion on Drug Discovery)
Source: Expert Opinion on Drug Discovery - August 12, 2020 Category: Drugs & Pharmacology Authors: Carlos F. M. Silva Diana C. G. A. Pinto Pedro A. Fernandes Artur M. S. Silva Source Type: research

Call for a paradigm shift in the design of universal influenza vaccines by harnessing multiple correlates of protection
. (Source: Expert Opinion on Drug Discovery)
Source: Expert Opinion on Drug Discovery - August 12, 2020 Category: Drugs & Pharmacology Authors: Yo Han Jang Baik L. Seong Source Type: research

Drug discovery strategies for modulating oxidative stress in gastrointestinal disorders
. (Source: Expert Opinion on Drug Discovery)
Source: Expert Opinion on Drug Discovery - August 4, 2020 Category: Drugs & Pharmacology Authors: Taraneh Mousavi Nastaran Hadizadeh Shekoufeh Nikfar Mohammad Abdollahi Source Type: research

Antimicrobial peptides: a promising strategy for lung cancer drug discovery?
. (Source: Expert Opinion on Drug Discovery)
Source: Expert Opinion on Drug Discovery - August 4, 2020 Category: Drugs & Pharmacology Authors: Farshid Zandsalimi Sam talaei Mehdi Noormohammad Ahari Shahin Aghamiri Pourya Raee Soheil Roshanzamiri Fatemeh Yarian Mojgan Bandehpour Zeinab Zohrab Zadeh Source Type: research

Open access in silico tools to predict the ADMET profiling of drug candidates
. (Source: Expert Opinion on Drug Discovery)
Source: Expert Opinion on Drug Discovery - July 31, 2020 Category: Drugs & Pharmacology Authors: Supratik Kar Jerzy Leszczynski Source Type: research

Preclinical discovery and clinical development of encorafenib for the treatment of melanoma
. (Source: Expert Opinion on Drug Discovery)
Source: Expert Opinion on Drug Discovery - July 28, 2020 Category: Drugs & Pharmacology Authors: Ilker N. Okten Sadeka Ismail Bethany M. Withycombe Zeynep Eroglu Source Type: research

Explaining biosimilars and how reverse engineering plays a critical role in their development
. (Source: Expert Opinion on Drug Discovery)
Source: Expert Opinion on Drug Discovery - July 27, 2020 Category: Drugs & Pharmacology Authors: Salvatore Bellinvia Christopher J. Edwards Source Type: research

The recent application of 3D-QSAR and docking studies to novel HIV-protease inhibitor drug discovery
. (Source: Expert Opinion on Drug Discovery)
Source: Expert Opinion on Drug Discovery - July 21, 2020 Category: Drugs & Pharmacology Authors: Fisayo A. Olotu Clement Agoni Opeyemi Soremekun Mahmoud E. S. Soliman Source Type: research

Lessons learned from the discovery of sodium valproate and what has this meant to future drug discovery efforts?
. (Source: Expert Opinion on Drug Discovery)
Source: Expert Opinion on Drug Discovery - July 20, 2020 Category: Drugs & Pharmacology Authors: Slobodan M. Jankovi ć Sne žana V. Janković Source Type: research

Should drug discovery scientists still embrace the amyloid hypothesis for Alzheimer ’s disease or should they be looking elsewhere?
. (Source: Expert Opinion on Drug Discovery)
Source: Expert Opinion on Drug Discovery - July 20, 2020 Category: Drugs & Pharmacology Authors: Bruno Pietro Imbimbo Stefania Ippati Mark Watling Source Type: research

The combination of artificial intelligence and systems biology for intelligent vaccine design
. (Source: Expert Opinion on Drug Discovery)
Source: Expert Opinion on Drug Discovery - July 14, 2020 Category: Drugs & Pharmacology Authors: Giulia Russo Pedro Reche Marzio Pennisi Francesco Pappalardo Source Type: research

Phage display technology for target determination of small-molecule therapeutics: an update
. (Source: Expert Opinion on Drug Discovery)
Source: Expert Opinion on Drug Discovery - July 13, 2020 Category: Drugs & Pharmacology Authors: Yoichi Takakusagi Kaori Takakusagi Kengo Sakaguchi Fumio Sugawara Source Type: research

Opportunities and challenges for drug discovery in modulating Adhesion G protein-coupled receptor (GPCR) functions
. (Source: Expert Opinion on Drug Discovery)
Source: Expert Opinion on Drug Discovery - July 10, 2020 Category: Drugs & Pharmacology Authors: Andrey D. Bondarev Misty M. Attwood J örgen Jonsson Vladimir N. Chubarev Vadim V. Tarasov Helgi B. Schi öth Source Type: research

What is on the horizon for type 2 diabetes pharmacotherapy? – An overview of the antidiabetic drug development pipeline
. (Source: Expert Opinion on Drug Discovery)
Source: Expert Opinion on Drug Discovery - July 10, 2020 Category: Drugs & Pharmacology Authors: Karl Sebastian Johansson David Sonne Filip Krag Knop Mikkel Bring Christensen Source Type: research

Automated patch clamp in drug discovery: major breakthroughs and innovation in the last decade
. (Source: Expert Opinion on Drug Discovery)
Source: Expert Opinion on Drug Discovery - July 10, 2020 Category: Drugs & Pharmacology Authors: Alison Obergrussberger S øren Friis Andrea Br üggemann Niels Fertig Source Type: research

Modeling percutaneous absorption for successful drug discovery and development
. (Source: Expert Opinion on Drug Discovery)
Source: Expert Opinion on Drug Discovery - June 25, 2020 Category: Drugs & Pharmacology Authors: Hanumanth Srikanth Cheruvu Xin Liu Jeffrey E. Grice Michael S. Roberts Source Type: research

What ketamine can teach us about the opioid system in depression?
. (Source: Expert Opinion on Drug Discovery)
Source: Expert Opinion on Drug Discovery - June 22, 2020 Category: Drugs & Pharmacology Authors: Laura Perez-Caballero Victor Perez Esther Berrocoso Source Type: research

Advances in the discovery and development of selective heme-displacing IDO1 inhibitors
. (Source: Expert Opinion on Drug Discovery)
Source: Expert Opinion on Drug Discovery - June 22, 2020 Category: Drugs & Pharmacology Authors: Lijun Sun Source Type: research

The preclinical discovery and development of agomelatine for the treatment of depression
. (Source: Expert Opinion on Drug Discovery)
Source: Expert Opinion on Drug Discovery - June 22, 2020 Category: Drugs & Pharmacology Authors: George Konstantakopoulos Stefanos Dimitrakopoulos Panayiota G. Michalopoulou Source Type: research

Developments in the discovery and design of intranasal antidepressants
. (Source: Expert Opinion on Drug Discovery)
Source: Expert Opinion on Drug Discovery - June 22, 2020 Category: Drugs & Pharmacology Authors: Ma łgorzata Panek Pawe ł Kawalec Andrzej Pilc W ładysław Lasoń Source Type: research

The chemical probe – scopes, limitations and challenges
. (Source: Expert Opinion on Drug Discovery)
Source: Expert Opinion on Drug Discovery - June 19, 2020 Category: Drugs & Pharmacology Authors: Holger Stark Source Type: research

The application of machine learning techniques to innovative antibacterial discovery and development
. (Source: Expert Opinion on Drug Discovery)
Source: Expert Opinion on Drug Discovery - June 17, 2020 Category: Drugs & Pharmacology Authors: Mateus S á Magalhães Serafim Thales Kronenberger Patr ícia Rufino Oliveira Antti Poso K áthia Maria Honório Bruno Eduardo Fernandes Mota Vin ícius Gonçalves Maltarollo Source Type: research

The increasing impact of Chinese innovative drug research on the global stage with a focus on drug discovery
. (Source: Expert Opinion on Drug Discovery)
Source: Expert Opinion on Drug Discovery - June 17, 2020 Category: Drugs & Pharmacology Authors: Wei Luo Cherukupalli Srinivasulu Xia Hao Xinyong Liu Peng Zhan Source Type: research

Why do SARS-COV vaccines not exist? The pharma scientific intelligence and business model must be revisited!
. (Source: Expert Opinion on Drug Discovery)
Source: Expert Opinion on Drug Discovery - June 16, 2020 Category: Drugs & Pharmacology Authors: Mohamed Boudjelal Atef Nehdi Imadul Islam Source Type: research

Targeting Autophagy In Disease: Recent Advances In Drug Discovery
. (Source: Expert Opinion on Drug Discovery)
Source: Expert Opinion on Drug Discovery - June 16, 2020 Category: Drugs & Pharmacology Authors: Dasol Kim Hui-Yun Hwang Ho Jeong Kwon Source Type: research

Peptide-based targeting of connexins and pannexins for therapeutic purposes
. (Source: Expert Opinion on Drug Discovery)
Source: Expert Opinion on Drug Discovery - June 15, 2020 Category: Drugs & Pharmacology Authors: Anne Caufriez Denise B öck Charlotte Martin Steven Ballet Mathieu Vinken Source Type: research

How effective are nonalcoholic fatty liver disease models for drug discovery?
. (Source: Expert Opinion on Drug Discovery)
Source: Expert Opinion on Drug Discovery - June 11, 2020 Category: Drugs & Pharmacology Authors: Jana Hundertmark Frank Tacke Source Type: research

Can quantitative pharmacology improve productivity in pharmaceutical research and development?
. (Source: Expert Opinion on Drug Discovery)
Source: Expert Opinion on Drug Discovery - June 8, 2020 Category: Drugs & Pharmacology Authors: Mayankbhai Patel Tjerk Bueters Source Type: research

What place does molecular topology have in today ’s drug discovery?
. (Source: Expert Opinion on Drug Discovery)
Source: Expert Opinion on Drug Discovery - June 4, 2020 Category: Drugs & Pharmacology Authors: Riccardo Zanni Maria Galvez-Llompart Ramon Garcia-Domenech Jorge Galvez Source Type: research

An up-to-date overview of computational polypharmacology in modern drug discovery
. (Source: Expert Opinion on Drug Discovery)
Source: Expert Opinion on Drug Discovery - May 26, 2020 Category: Drugs & Pharmacology Authors: Rajan Chaudhari Long Wolf Fong Zhi Tan Beibei Huang Shuxing Zhang Source Type: research

An update on the use of molecular modeling in dendrimers design for biomedical applications: are we using its full potential?
. (Source: Expert Opinion on Drug Discovery)
Source: Expert Opinion on Drug Discovery - May 26, 2020 Category: Drugs & Pharmacology Authors: Mire Zloh Teresa S. Barata Source Type: research

The preclinical discovery and development of opicapone for the treatment of Parkinson ’s disease
. (Source: Expert Opinion on Drug Discovery)
Source: Expert Opinion on Drug Discovery - May 26, 2020 Category: Drugs & Pharmacology Authors: Miren Ettcheto Oriol Busquets Elena S ánchez-Lopez Amanda Cano Patricia R. Manzine Ester Verdaguer Jordi Olloquequi Carme Auladell Jaume Folch Antoni Camins Source Type: research

Antibacterial medicinal chemistry – what can we design for?
. (Source: Expert Opinion on Drug Discovery)
Source: Expert Opinion on Drug Discovery - May 26, 2020 Category: Drugs & Pharmacology Authors: Alastair L. Parkes Source Type: research