Drug development for noise-induced hearing loss
. (Source: Expert Opinion on Drug Discovery)
Source: Expert Opinion on Drug Discovery - August 24, 2020 Category: Drugs & Pharmacology Authors: Isabel Varela-Nieto Silvia Murillo-Cuesta Miryam Calvino Rafael Cediel Luis Lassaletta Source Type: research

Animal models of Chagas disease and their translational value to drug development
. (Source: Expert Opinion on Drug Discovery)
Source: Expert Opinion on Drug Discovery - August 18, 2020 Category: Drugs & Pharmacology Authors: Eric Chatelain Ivan Scandale Source Type: research

Evolution of chromone-like compounds as potential antileishmanial agents, through the 21st century
. (Source: Expert Opinion on Drug Discovery)
Source: Expert Opinion on Drug Discovery - August 11, 2020 Category: Drugs & Pharmacology Authors: Carlos F. M. Silva Diana C. G. A. Pinto Pedro A. Fernandes Artur M. S. Silva Source Type: research

Call for a paradigm shift in the design of universal influenza vaccines by harnessing multiple correlates of protection
. (Source: Expert Opinion on Drug Discovery)
Source: Expert Opinion on Drug Discovery - August 11, 2020 Category: Drugs & Pharmacology Authors: Yo Han Jang Baik L. Seong Source Type: research

Drug discovery strategies for modulating oxidative stress in gastrointestinal disorders
. (Source: Expert Opinion on Drug Discovery)
Source: Expert Opinion on Drug Discovery - August 3, 2020 Category: Drugs & Pharmacology Authors: Taraneh Mousavi Nastaran Hadizadeh Shekoufeh Nikfar Mohammad Abdollahi Source Type: research

Antimicrobial peptides: a promising strategy for lung cancer drug discovery?
. (Source: Expert Opinion on Drug Discovery)
Source: Expert Opinion on Drug Discovery - August 3, 2020 Category: Drugs & Pharmacology Authors: Farshid Zandsalimi Sam talaei Mehdi Noormohammad Ahari Shahin Aghamiri Pourya Raee Soheil Roshanzamiri Fatemeh Yarian Mojgan Bandehpour Zeinab Zohrab Zadeh Source Type: research

Open access in silico tools to predict the ADMET profiling of drug candidates
. (Source: Expert Opinion on Drug Discovery)
Source: Expert Opinion on Drug Discovery - July 30, 2020 Category: Drugs & Pharmacology Authors: Supratik Kar Jerzy Leszczynski Source Type: research

Preclinical discovery and clinical development of encorafenib for the treatment of melanoma
. (Source: Expert Opinion on Drug Discovery)
Source: Expert Opinion on Drug Discovery - July 27, 2020 Category: Drugs & Pharmacology Authors: Ilker N. Okten Sadeka Ismail Bethany M. Withycombe Zeynep Eroglu Source Type: research

Explaining biosimilars and how reverse engineering plays a critical role in their development
. (Source: Expert Opinion on Drug Discovery)
Source: Expert Opinion on Drug Discovery - July 26, 2020 Category: Drugs & Pharmacology Authors: Salvatore Bellinvia Christopher J. Edwards Source Type: research

The recent application of 3D-QSAR and docking studies to novel HIV-protease inhibitor drug discovery
. (Source: Expert Opinion on Drug Discovery)
Source: Expert Opinion on Drug Discovery - July 20, 2020 Category: Drugs & Pharmacology Authors: Fisayo A. Olotu Clement Agoni Opeyemi Soremekun Mahmoud E. S. Soliman Source Type: research

Lessons learned from the discovery of sodium valproate and what has this meant to future drug discovery efforts?
. (Source: Expert Opinion on Drug Discovery)
Source: Expert Opinion on Drug Discovery - July 19, 2020 Category: Drugs & Pharmacology Authors: Slobodan M. Jankovi ć Sne žana V. Janković Source Type: research

Should drug discovery scientists still embrace the amyloid hypothesis for Alzheimer ’s disease or should they be looking elsewhere?
. (Source: Expert Opinion on Drug Discovery)
Source: Expert Opinion on Drug Discovery - July 19, 2020 Category: Drugs & Pharmacology Authors: Bruno Pietro Imbimbo Stefania Ippati Mark Watling Source Type: research

The combination of artificial intelligence and systems biology for intelligent vaccine design
. (Source: Expert Opinion on Drug Discovery)
Source: Expert Opinion on Drug Discovery - July 13, 2020 Category: Drugs & Pharmacology Authors: Giulia Russo Pedro Reche Marzio Pennisi Francesco Pappalardo Source Type: research

Phage display technology for target determination of small-molecule therapeutics: an update
. (Source: Expert Opinion on Drug Discovery)
Source: Expert Opinion on Drug Discovery - July 12, 2020 Category: Drugs & Pharmacology Authors: Yoichi Takakusagi Kaori Takakusagi Kengo Sakaguchi Fumio Sugawara Source Type: research

Opportunities and challenges for drug discovery in modulating Adhesion G protein-coupled receptor (GPCR) functions
. (Source: Expert Opinion on Drug Discovery)
Source: Expert Opinion on Drug Discovery - July 9, 2020 Category: Drugs & Pharmacology Authors: Andrey D. Bondarev Misty M. Attwood J örgen Jonsson Vladimir N. Chubarev Vadim V. Tarasov Helgi B. Schi öth Source Type: research

What is on the horizon for type 2 diabetes pharmacotherapy? – An overview of the antidiabetic drug development pipeline
. (Source: Expert Opinion on Drug Discovery)
Source: Expert Opinion on Drug Discovery - July 9, 2020 Category: Drugs & Pharmacology Authors: Karl Sebastian Johansson David Sonne Filip Krag Knop Mikkel Bring Christensen Source Type: research

Automated patch clamp in drug discovery: major breakthroughs and innovation in the last decade
. (Source: Expert Opinion on Drug Discovery)
Source: Expert Opinion on Drug Discovery - July 9, 2020 Category: Drugs & Pharmacology Authors: Alison Obergrussberger S øren Friis Andrea Br üggemann Niels Fertig Source Type: research

Modeling percutaneous absorption for successful drug discovery and development
. (Source: Expert Opinion on Drug Discovery)
Source: Expert Opinion on Drug Discovery - June 24, 2020 Category: Drugs & Pharmacology Authors: Hanumanth Srikanth Cheruvu Xin Liu Jeffrey E. Grice Michael S. Roberts Source Type: research

What ketamine can teach us about the opioid system in depression?
. (Source: Expert Opinion on Drug Discovery)
Source: Expert Opinion on Drug Discovery - June 21, 2020 Category: Drugs & Pharmacology Authors: Laura Perez-Caballero Victor Perez Esther Berrocoso Source Type: research

Advances in the discovery and development of selective heme-displacing IDO1 inhibitors
. (Source: Expert Opinion on Drug Discovery)
Source: Expert Opinion on Drug Discovery - June 21, 2020 Category: Drugs & Pharmacology Authors: Lijun Sun Source Type: research

The preclinical discovery and development of agomelatine for the treatment of depression
. (Source: Expert Opinion on Drug Discovery)
Source: Expert Opinion on Drug Discovery - June 21, 2020 Category: Drugs & Pharmacology Authors: George Konstantakopoulos Stefanos Dimitrakopoulos Panayiota G. Michalopoulou Source Type: research

Developments in the discovery and design of intranasal antidepressants
. (Source: Expert Opinion on Drug Discovery)
Source: Expert Opinion on Drug Discovery - June 21, 2020 Category: Drugs & Pharmacology Authors: Ma łgorzata Panek Pawe ł Kawalec Andrzej Pilc W ładysław Lasoń Source Type: research

The chemical probe – scopes, limitations and challenges
. (Source: Expert Opinion on Drug Discovery)
Source: Expert Opinion on Drug Discovery - June 18, 2020 Category: Drugs & Pharmacology Authors: Holger Stark Source Type: research

The application of machine learning techniques to innovative antibacterial discovery and development
. (Source: Expert Opinion on Drug Discovery)
Source: Expert Opinion on Drug Discovery - June 16, 2020 Category: Drugs & Pharmacology Authors: Mateus S á Magalhães Serafim Thales Kronenberger Patr ícia Rufino Oliveira Antti Poso K áthia Maria Honório Bruno Eduardo Fernandes Mota Vin ícius Gonçalves Maltarollo Source Type: research

The increasing impact of Chinese innovative drug research on the global stage with a focus on drug discovery
. (Source: Expert Opinion on Drug Discovery)
Source: Expert Opinion on Drug Discovery - June 16, 2020 Category: Drugs & Pharmacology Authors: Wei Luo Cherukupalli Srinivasulu Xia Hao Xinyong Liu Peng Zhan Source Type: research

Why do SARS-COV vaccines not exist? The pharma scientific intelligence and business model must be revisited!
. (Source: Expert Opinion on Drug Discovery)
Source: Expert Opinion on Drug Discovery - June 15, 2020 Category: Drugs & Pharmacology Authors: Mohamed Boudjelal Atef Nehdi Imadul Islam Source Type: research

Targeting Autophagy In Disease: Recent Advances In Drug Discovery
. (Source: Expert Opinion on Drug Discovery)
Source: Expert Opinion on Drug Discovery - June 15, 2020 Category: Drugs & Pharmacology Authors: Dasol Kim Hui-Yun Hwang Ho Jeong Kwon Source Type: research

Peptide-based targeting of connexins and pannexins for therapeutic purposes
. (Source: Expert Opinion on Drug Discovery)
Source: Expert Opinion on Drug Discovery - June 14, 2020 Category: Drugs & Pharmacology Authors: Anne Caufriez Denise B öck Charlotte Martin Steven Ballet Mathieu Vinken Source Type: research

How effective are nonalcoholic fatty liver disease models for drug discovery?
. (Source: Expert Opinion on Drug Discovery)
Source: Expert Opinion on Drug Discovery - June 10, 2020 Category: Drugs & Pharmacology Authors: Jana Hundertmark Frank Tacke Source Type: research

Can quantitative pharmacology improve productivity in pharmaceutical research and development?
. (Source: Expert Opinion on Drug Discovery)
Source: Expert Opinion on Drug Discovery - June 7, 2020 Category: Drugs & Pharmacology Authors: Mayankbhai Patel Tjerk Bueters Source Type: research

What place does molecular topology have in today ’s drug discovery?
. (Source: Expert Opinion on Drug Discovery)
Source: Expert Opinion on Drug Discovery - June 3, 2020 Category: Drugs & Pharmacology Authors: Riccardo Zanni Maria Galvez-Llompart Ramon Garcia-Domenech Jorge Galvez Source Type: research

An up-to-date overview of computational polypharmacology in modern drug discovery
. (Source: Expert Opinion on Drug Discovery)
Source: Expert Opinion on Drug Discovery - May 25, 2020 Category: Drugs & Pharmacology Authors: Rajan Chaudhari Long Wolf Fong Zhi Tan Beibei Huang Shuxing Zhang Source Type: research

An update on the use of molecular modeling in dendrimers design for biomedical applications: are we using its full potential?
. (Source: Expert Opinion on Drug Discovery)
Source: Expert Opinion on Drug Discovery - May 25, 2020 Category: Drugs & Pharmacology Authors: Mire Zloh Teresa S. Barata Source Type: research

The preclinical discovery and development of opicapone for the treatment of Parkinson ’s disease
. (Source: Expert Opinion on Drug Discovery)
Source: Expert Opinion on Drug Discovery - May 25, 2020 Category: Drugs & Pharmacology Authors: Miren Ettcheto Oriol Busquets Elena S ánchez-Lopez Amanda Cano Patricia R. Manzine Ester Verdaguer Jordi Olloquequi Carme Auladell Jaume Folch Antoni Camins Source Type: research

Antibacterial medicinal chemistry – what can we design for?
. (Source: Expert Opinion on Drug Discovery)
Source: Expert Opinion on Drug Discovery - May 25, 2020 Category: Drugs & Pharmacology Authors: Alastair L. Parkes Source Type: research

Novel therapeutic and drug development strategies for tobacco use disorder: endocannabinoid modulation
. (Source: Expert Opinion on Drug Discovery)
Source: Expert Opinion on Drug Discovery - May 18, 2020 Category: Drugs & Pharmacology Authors: Kevin Butler Bernard Le Foll Source Type: research

Pluripotent stem cells for neurodegenerative disease modeling: an expert view on their value to drug discovery
. (Source: Expert Opinion on Drug Discovery)
Source: Expert Opinion on Drug Discovery - May 18, 2020 Category: Drugs & Pharmacology Authors: Shi-Dong Chen Hong-Qi Li Mei Cui Qiang Dong Jin-Tai Yu Source Type: research

How to address challenges and opportunities in pediatric cancer drug development?
. (Source: Expert Opinion on Drug Discovery)
Source: Expert Opinion on Drug Discovery - May 17, 2020 Category: Drugs & Pharmacology Authors: Lucas Moreno Steven G DuBois Lynley V Marshall Elizabeth Fox Fernando Carceller Andrew Dj Pearson Source Type: research

Challenges identifying efficacious miRNA therapeutics for cancer
. (Source: Expert Opinion on Drug Discovery)
Source: Expert Opinion on Drug Discovery - May 17, 2020 Category: Drugs & Pharmacology Authors: Meirav Segal Frank J. Slack Source Type: research

In vivo near-infrared fluorescent optical imaging for CNS drug discovery
. (Source: Expert Opinion on Drug Discovery)
Source: Expert Opinion on Drug Discovery - May 11, 2020 Category: Drugs & Pharmacology Authors: Maria J. Moreno Binbing Ling Danica B. Stanimirovic Source Type: research

Current models of pulmonary fibrosis for future drug discovery efforts
. (Source: Expert Opinion on Drug Discovery)
Source: Expert Opinion on Drug Discovery - May 11, 2020 Category: Drugs & Pharmacology Authors: Toyoshi Yanagihara Sy Giin Chong Megan Vierhout Jeremy A. Hirota Kjetil Ask Martin Kolb Source Type: research

Porcine cancer models: potential tools to enhance cancer drug trials
. (Source: Expert Opinion on Drug Discovery)
Source: Expert Opinion on Drug Discovery - May 6, 2020 Category: Drugs & Pharmacology Authors: Noah Robertson Lawrence B. Schook Kyle M. Schachtschneider Source Type: research

High-throughput screening in multicellular spheroids for target discovery in the tumor microenvironment
. (Source: Expert Opinion on Drug Discovery)
Source: Expert Opinion on Drug Discovery - May 3, 2020 Category: Drugs & Pharmacology Authors: Blaise Calpe Werner J. Kovacs Source Type: research

Advances of droplet-based microfluidics in drug discovery
. (Source: Expert Opinion on Drug Discovery)
Source: Expert Opinion on Drug Discovery - April 29, 2020 Category: Drugs & Pharmacology Authors: Yuetong Wang Zhuoyue Chen Feika Bian Luoran Shang Kaixuan Zhu Yuanjin Zhao Source Type: research

The emerging role of computational design in peptide macrocycle drug discovery
. (Source: Expert Opinion on Drug Discovery)
Source: Expert Opinion on Drug Discovery - April 28, 2020 Category: Drugs & Pharmacology Authors: Vikram K. Mulligan Source Type: research

Is high performance computing a requirement for novel drug discovery and how will this impact academic efforts?
. (Source: Expert Opinion on Drug Discovery)
Source: Expert Opinion on Drug Discovery - April 28, 2020 Category: Drugs & Pharmacology Authors: Sav íns Puertas-Martín Antonio J. Banegas-Luna Mar ía Paredes-Ramos Juana L. Redondo Pilar M. Ortigosa Ol ’Ha O. Brovarets' Horacio P érez-Sánchez Source Type: research

Novel approaches and current challenges with targeting the endocannabinoid system
. (Source: Expert Opinion on Drug Discovery)
Source: Expert Opinion on Drug Discovery - April 26, 2020 Category: Drugs & Pharmacology Authors: Paula Morales Nadine Jagerovic Source Type: research

Recent approaches to gout drug discovery: an update
. (Source: Expert Opinion on Drug Discovery)
Source: Expert Opinion on Drug Discovery - April 23, 2020 Category: Drugs & Pharmacology Authors: Naoyuki Otani Motoshi Ouchi Hideo Kudo Shuichi Tsuruoka Ichiro Hisatome Naohiko Anzai Source Type: research

Advances in the discovery of fatty acid amide hydrolase inhibitors: what does the future hold?
. (Source: Expert Opinion on Drug Discovery)
Source: Expert Opinion on Drug Discovery - April 14, 2020 Category: Drugs & Pharmacology Authors: Domenico Fazio Emanuele Criscuolo Alessandra Piccoli Barbara Barboni Filomena Fezza Mauro Maccarrone Source Type: research

The preclinical discovery and development of the combination of ivacaftor + tezacaftor used to treat cystic fibrosis
. (Source: Expert Opinion on Drug Discovery)
Source: Expert Opinion on Drug Discovery - April 14, 2020 Category: Drugs & Pharmacology Authors: Lorenzo Guerra Maria Favia Sante Di Gioia Onofrio Laselva Arianna Bisogno Valeria Casavola Carla Colombo Massimo Conese Source Type: research