Tools and techniques for the discovery of therapeutic aptamers: recent advances
. (Source: Expert Opinion on Drug Discovery)
Source: Expert Opinion on Drug Discovery - October 16, 2023 Category: Drugs & Pharmacology Authors: Lili AiXinyi JiangKejing ZhangCheng CuiBo LiuWeihong Tana Molecular Science and Biomedicine Laboratory (MBL), State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, College of Biology, Aptamer Engineering Source Type: research

Lessons learnt from the preclinical discovery and development of ensitrelvir as a COVID-19 therapeutic option
. (Source: Expert Opinion on Drug Discovery)
Source: Expert Opinion on Drug Discovery - October 13, 2023 Category: Drugs & Pharmacology Authors: Sara FerraroIrma ConvertinoEmiliano CappelloGiulia ValdiserraMarco BonasoMarco Tuccoria Unit of Pharmacology and Pharmacovigilance, Department of Clinical and Experimental Medicine, University of Pisa, Pisa Italyb Unit of Adverse Drug Reaction Monitoring, Source Type: research

Current advances in the use of bioluminescence assays for drug discovery: an update of the last ten years
. (Source: Expert Opinion on Drug Discovery)
Source: Expert Opinion on Drug Discovery - October 10, 2023 Category: Drugs & Pharmacology Authors: Maria Maddalena CalabrettaElisa Michelinia Department of Chemistry “Giacomo Ciamician”, Alma Mater Studiorum-University of Bologna, Bologna, Italyb Center for Applied Biomedical Research (CRBA), IRCCS St. Orsola Hospital, Bologna, Italyc Health Scienc Source Type: research

The application of WaterMap-guided structure-based virtual screening in novel drug discovery
. (Source: Expert Opinion on Drug Discovery)
Source: Expert Opinion on Drug Discovery - October 9, 2023 Category: Drugs & Pharmacology Authors: Agnieszka A. KaczorAgata Zi ębaDariusz Matosiuka Department of Synthesis and Chemical Technology of Pharmaceutical Substances with Computer Modeling Laboratory, Faculty of Pharmacy, Lublin, Polandb School of Pharmacy, University of Eastern Finland, Kuopi Source Type: research

Advances in protein kinase drug discovery through targeting gatekeeper mutations
. (Source: Expert Opinion on Drug Discovery)
Source: Expert Opinion on Drug Discovery - October 9, 2023 Category: Drugs & Pharmacology Authors: Jing GuoYang ZhouXiaoyun LuInternational Cooperative Laboratory of Traditional Chinese Medicine Modernization and Innovative Drug Discovery of Chinese Ministry of Education (MOE), Guangzhou City Key Laboratory of Precision Chemical Drug Development, Schoo Source Type: research

Leveraging nitrogen occurrence in approved drugs to identify structural patterns
. (Source: Expert Opinion on Drug Discovery)
Source: Expert Opinion on Drug Discovery - October 9, 2023 Category: Drugs & Pharmacology Authors: Vijay H. MasandSami Al-HussainAbdullah Y. AlzahraniNahed N. E. El-SayedChien Ing YeoYee Seng TanMagdi E.A. Zakia Department of Chemistry, Vidya Bharati Mahavidyalaya, Amravati, Indiab Department of Chemistry, Faculty of Science, Imam Mohammad Ibn Saud Isl Source Type: research

Advances in the discovery of heterocyclic-based drugs against Alzheimer ’s disease
. (Source: Expert Opinion on Drug Discovery)
Source: Expert Opinion on Drug Discovery - October 6, 2023 Category: Drugs & Pharmacology Authors: Juan D. S ánchezAndrés R. AlcántaraJuan F. GonzálezJosé María Sánchez-MonteroDepartamento de Química en Ciencias Farmacéuticas, Facultad de Farmacia, Universidad Complutense de Madrid, Madrid, Spain Source Type: research

Calcium channel blockers ’ contribution to overcoming Current drug discovery challenges in Alzheimer’s disease
. (Source: Expert Opinion on Drug Discovery)
Source: Expert Opinion on Drug Discovery - October 6, 2023 Category: Drugs & Pharmacology Authors: Paul J BernardDjamila BelliliLhassane IsmailiUniversit é de Franche-Comté, LINC, UFR Santé, Pôle de Chimie Médicinale, Besançon, France Source Type: research

Applying network link prediction in drug discovery: an overview of the literature
. (Source: Expert Opinion on Drug Discovery)
Source: Expert Opinion on Drug Discovery - October 5, 2023 Category: Drugs & Pharmacology Authors: Jeongtae SonDongsup KimDepartment of Bio and Brain Engineering, Korea Advanced Institute of Science and Technology, Daejeon, Republic of Korea Source Type: research

Deep learning tools to accelerate antibiotic discovery
. (Source: Expert Opinion on Drug Discovery)
Source: Expert Opinion on Drug Discovery - October 5, 2023 Category: Drugs & Pharmacology Authors: Angela CesaroMojtaba BagheriMarcelo TorresFangping WanCesar de la Fuente-Nuneza Machine Biology Group, Departments of Psychiatry and Microbiology, Institute for Biomedical Informatics, Institute for Translational Medicine and Therapeutics, Perelman School Source Type: research

15 Years of molecular simulation of drug-binding kinetics
. (Source: Expert Opinion on Drug Discovery)
Source: Expert Opinion on Drug Discovery - October 4, 2023 Category: Drugs & Pharmacology Authors: Chung F. WongDepartment of Chemistry and Biochemistry, University of Missouri-St. Louis, St. Louis, MO, USA Source Type: research

Integrating Liver-Chip data into pharmaceutical decision-making processes
. (Source: Expert Opinion on Drug Discovery)
Source: Expert Opinion on Drug Discovery - September 13, 2023 Category: Drugs & Pharmacology Authors: Daniel Levner Lorna Ewart Source Type: research

Mapping strategies towards improved external validity in preclinical translational research
. (Source: Expert Opinion on Drug Discovery)
Source: Expert Opinion on Drug Discovery - September 11, 2023 Category: Drugs & Pharmacology Authors: Clarissa F. D. Carneiro Natascha Drude Maren H ülsemann Anja Collazo Ulf Toelch Source Type: research

Molecular simulations required to target novel and potent inhibitors of cancer invasion
. (Source: Expert Opinion on Drug Discovery)
Source: Expert Opinion on Drug Discovery - September 7, 2023 Category: Drugs & Pharmacology Authors: Tian Lu Tong Li Meng-Ke Wu Chi-Chong Zheng Xue-Mei He Hai-Liang Zhu Li Li Ruo-Jun Man Source Type: research

Applications of graphene-based nanomaterials in drug design: The good, the bad and the ugly
. (Source: Expert Opinion on Drug Discovery)
Source: Expert Opinion on Drug Discovery - September 4, 2023 Category: Drugs & Pharmacology Authors: Zhengfeng Gao Siyao Qin C écilia Ménard-Moyon Alberto Bianco Source Type: research