Radioactive Iodine in Differentiated Carcinoma of Thyroid: An Overview
Curr Radiopharm. 2023 Oct 24. doi: 10.2174/0118744710249684231013072013. Online ahead of print.ABSTRACTThyroid cancer is the fifth most prevalent cancer in women and the fastest-growing malignancy. Although surgery is still the basis of treatment, internal radiation therapy [Brachytherapy] with radioactive iodine-131, which functions by releasing beta particles with low tissue penetration and causing DNA damage, is also a potential option. The three basic aims of RAI therapy in well-differentiated thyroid tumors are ablation of the remnant, adjuvant therapy, and disease management. Radioactive iodine dose is selected in on...
Source: Current Radiopharmaceuticals - October 25, 2023 Category: Radiology Authors: Namit Kant Singh Balaji Ramamourthy Neemu Hage Sushmitha Nagaraju Krishna Medha Kappagantu Source Type: research

The Anti-hypoxia Potentials of Trans-sodium Crocetinate in Hypoxiarelated Diseases: A Review
Curr Radiopharm. 2023 Oct 24. doi: 10.2174/0118744710268127231020083505. Online ahead of print.ABSTRACTCrocetin is a kind of apocarotenoid carboxylic acid extracted from saffron (Crocus sativus L.), which is effective in upregulating tissue oxygenation. However, crocetin is difficult to solubilize. It was shown that the trans isomer of crocetin is effective in improving oxygen diffusivity, while its cis isomer appears not to be. Hence, the isolated trans isomer of crocetin or trans-sodium crocetinate (TSC) can be used instead of crocetin. It is shown that TSC can upregulate hypoxic tissue oxygenation and be effective in tr...
Source: Current Radiopharmaceuticals - October 25, 2023 Category: Radiology Authors: Natalia S Klunko Harun Achmad Tamara Muayad Abdullah Sami Mohammed Indranil Saha Khulood Saadoon Salim Rasha Fadhel Obaid Rosario Mireya Romero-Parra Shaker Shanawa Al-Hasnawi Wissam Hamid Al-Janabi Bagher Farhood Source Type: research

Radioactive Iodine in Differentiated Carcinoma of Thyroid: An Overview
Curr Radiopharm. 2023 Oct 24. doi: 10.2174/0118744710249684231013072013. Online ahead of print.ABSTRACTThyroid cancer is the fifth most prevalent cancer in women and the fastest-growing malignancy. Although surgery is still the basis of treatment, internal radiation therapy [Brachytherapy] with radioactive iodine-131, which functions by releasing beta particles with low tissue penetration and causing DNA damage, is also a potential option. The three basic aims of RAI therapy in well-differentiated thyroid tumors are ablation of the remnant, adjuvant therapy, and disease management. Radioactive iodine dose is selected in on...
Source: Current Radiopharmaceuticals - October 25, 2023 Category: Radiology Authors: Namit Kant Singh Balaji Ramamourthy Neemu Hage Sushmitha Nagaraju Krishna Medha Kappagantu Source Type: research

The Anti-hypoxia Potentials of Trans-sodium Crocetinate in Hypoxiarelated Diseases: A Review
Curr Radiopharm. 2023 Oct 24. doi: 10.2174/0118744710268127231020083505. Online ahead of print.ABSTRACTCrocetin is a kind of apocarotenoid carboxylic acid extracted from saffron (Crocus sativus L.), which is effective in upregulating tissue oxygenation. However, crocetin is difficult to solubilize. It was shown that the trans isomer of crocetin is effective in improving oxygen diffusivity, while its cis isomer appears not to be. Hence, the isolated trans isomer of crocetin or trans-sodium crocetinate (TSC) can be used instead of crocetin. It is shown that TSC can upregulate hypoxic tissue oxygenation and be effective in tr...
Source: Current Radiopharmaceuticals - October 25, 2023 Category: Radiology Authors: Natalia S Klunko Harun Achmad Tamara Muayad Abdullah Sami Mohammed Indranil Saha Khulood Saadoon Salim Rasha Fadhel Obaid Rosario Mireya Romero-Parra Shaker Shanawa Al-Hasnawi Wissam Hamid Al-Janabi Bagher Farhood Source Type: research

Radioactive Iodine in Differentiated Carcinoma of Thyroid: An Overview
Curr Radiopharm. 2023 Oct 24. doi: 10.2174/0118744710249684231013072013. Online ahead of print.ABSTRACTThyroid cancer is the fifth most prevalent cancer in women and the fastest-growing malignancy. Although surgery is still the basis of treatment, internal radiation therapy [Brachytherapy] with radioactive iodine-131, which functions by releasing beta particles with low tissue penetration and causing DNA damage, is also a potential option. The three basic aims of RAI therapy in well-differentiated thyroid tumors are ablation of the remnant, adjuvant therapy, and disease management. Radioactive iodine dose is selected in on...
Source: Current Radiopharmaceuticals - October 25, 2023 Category: Radiology Authors: Namit Kant Singh Balaji Ramamourthy Neemu Hage Sushmitha Nagaraju Krishna Medha Kappagantu Source Type: research

New Advances in Mammography as Guidance for Vacuum-assisted Breast Biopsy: A Complete Tool for Radiologists
Curr Radiopharm. 2023 Oct 20. doi: 10.2174/0118744710242014231016094608. Online ahead of print.NO ABSTRACTPMID:37867261 | DOI:10.2174/0118744710242014231016094608 (Source: Current Radiopharmaceuticals)
Source: Current Radiopharmaceuticals - October 23, 2023 Category: Radiology Authors: Daniele Ugo Tari Source Type: research

A Novel Dual-labeled Peptide for Multimodal Imaging of EGFR with L858R Mutation
CONCLUSION: Specific binding of 99mTc STHHYYP-ECGK-TAMRA to L858R-mutated EGFRpositive NCI-H1975 cells and tumors was demonstrated in in vivo and in vitro studies. The results suggest that 99mTc STHHYYP-ECGK-TAMRA is a good candidate agent for dualmodality imaging targeting EGFR with L858R mutation.PMID:37849228 | DOI:10.2174/0118744710249198231002055810 (Source: Current Radiopharmaceuticals)
Source: Current Radiopharmaceuticals - October 18, 2023 Category: Radiology Authors: Myoung Hyoun Kim Seul-Gi Kim Dae-Weung Kim Source Type: research

Radiolabeling of Zonisamide for a Diagnostic Perspective
CONCLUSION: This study showed that the current radiolabeled antiepileptic drug has a diagnostic potential to be used in imaging neurological processes.PMID:37818565 | DOI:10.2174/0118744710249156231002115024 (Source: Current Radiopharmaceuticals)
Source: Current Radiopharmaceuticals - October 11, 2023 Category: Radiology Authors: Emine Dervis Kadriye Busra Karatay Kubra Durkan Ayfer Yurt Kilcar Source Type: research