Automated Synthesis of [11C]PiB via [11CH3OTf]-as Methylating Agent for PET Imaging of β-Amyloid
CONCLUSION: A reliable methodology was developed for preparing precursor followed by fully automated radiolabeling using [11C]MeOTf as a methylating agent to synthesize [11C]PiB. The final HPLC-free purification yielded more than 97% radiochemical purity tracer within one radionuclide half-life. The method was reproducible and efficient for any clinical center.PMID:38454773 | DOI:10.2174/0118744710295705240229114137 (Source: Current Radiopharmaceuticals)
Source: Current Radiopharmaceuticals - March 8, 2024 Category: Radiology Authors: Akhilesh K Singh Sanjay Gambhir Manish Dixit Source Type: research
"One Method to Label Them All": A Single Fully Automated Protocol for GMP-Compliant 68Ga Radiolabeling of PSMA-11, Transposable to PSMA-I & amp;T and PSMA-617
CONCLUSION: A single automated radiolabeling method on the GAIA® module was developed and implemented for 68Ga radiolabeling of 3 PSMA ligands, with slight adjustments for each molecule.PMID:38424422 | DOI:10.2174/0118744710293461240219111852 (Source: Current Radiopharmaceuticals)
Source: Current Radiopharmaceuticals - February 29, 2024 Category: Radiology Authors: Juliette Fouillet Charlotte Donz é Emmanuel Deshayes Lore Santoro L éa Rubira Cyril Fersing Source Type: research
