A Novel Dual-labeled Peptide for Multimodal Imaging of EGFR with L858R Mutation

CONCLUSION: Specific binding of 99mTc STHHYYP-ECGK-TAMRA to L858R-mutated EGFRpositive NCI-H1975 cells and tumors was demonstrated in in vivo and in vitro studies. The results suggest that 99mTc STHHYYP-ECGK-TAMRA is a good candidate agent for dualmodality imaging targeting EGFR with L858R mutation.PMID:37849228 | DOI:10.2174/0118744710249198231002055810
Source: Current Radiopharmaceuticals - Category: Radiology Authors: Source Type: research