A New Buffer for Gallium-68 Labeling Suitable for Use in Nuclear Medicine; Triethanolamine (TEA)
CONCLUSION: We present an alternative procedure for labeling PSMA-HBED-CC and DOTATATE peptides with [68GaCl3] to obtain high radioactive doses of final radiopharmaceutical products used in nuclear medicine clinical applications. We have provided a quality-controlled final product that can be used in clinical diagnostic procedures. With the use of an alternative buffer, these methods could be adapted to semi-automatic or automated modules routinely used in nuclear medicine laboratories to label [68Ga]-based radiopharmaceuticals.PMID:37218205 | DOI:10.2174/1874471016666230522100024 (Source: Current Radiopharmaceuticals)
Source: Current Radiopharmaceuticals - May 23, 2023 Category: Radiology Authors: Ay şe Uğur Olga Yaylal ı Do ğangün Yüksel Source Type: research

Evaluation of bone scan index as a prognostic tool in breast cancer patients with bone metastasis
CONCLUSION: Although the BSI significantly predicts OS in prostate cancer and in other tumors, we observed that the metastatic load of bone disease has not a key role in prognostic stratification in our population.PMID:37218206 | DOI:10.2174/1874471016666230509113108 (Source: Current Radiopharmaceuticals)
Source: Current Radiopharmaceuticals - May 23, 2023 Category: Radiology Authors: Maria Silvia De Feo Viviana Frantellizzi Arianna Di Rocco Alessio Farcomeni Andrea Marongiu Antonio Matto Susanna Nuvoli Angela Spanu Giuseppe De Vincentis Source Type: research

A New Buffer for Gallium-68 Labeling Suitable for Use in Nuclear Medicine; Triethanolamine (TEA)
CONCLUSION: We present an alternative procedure for labeling PSMA-HBED-CC and DOTATATE peptides with [68GaCl3] to obtain high radioactive doses of final radiopharmaceutical products used in nuclear medicine clinical applications. We have provided a quality-controlled final product that can be used in clinical diagnostic procedures. With the use of an alternative buffer, these methods could be adapted to semi-automatic or automated modules routinely used in nuclear medicine laboratories to label [68Ga]-based radiopharmaceuticals.PMID:37218205 | DOI:10.2174/1874471016666230522100024 (Source: Current Radiopharmaceuticals)
Source: Current Radiopharmaceuticals - May 23, 2023 Category: Radiology Authors: Ay şe Uğur Olga Yaylal ı Do ğangün Yüksel Source Type: research

Evaluation of bone scan index as a prognostic tool in breast cancer patients with bone metastasis
CONCLUSION: Although the BSI significantly predicts OS in prostate cancer and in other tumors, we observed that the metastatic load of bone disease has not a key role in prognostic stratification in our population.PMID:37218206 | DOI:10.2174/1874471016666230509113108 (Source: Current Radiopharmaceuticals)
Source: Current Radiopharmaceuticals - May 23, 2023 Category: Radiology Authors: Maria Silvia De Feo Viviana Frantellizzi Arianna Di Rocco Alessio Farcomeni Andrea Marongiu Antonio Matto Susanna Nuvoli Angela Spanu Giuseppe De Vincentis Source Type: research

Rethinking Tako-tsubo Cardiomyopathy: The Contribution of Myocardial Pathology and Molecular Imaging
CONCLUSION: TTC is characterized by acute transient left ventricular systolic dysfunction, which can be challenging to distinguish from myocardial infarction at presentation. Catecholamine-induced myocardial injury is the most established theory, but other factors, including myocardial metabolism and perfusion, should be considered of utmost importance. Each effort to clarify the numerous pathways and emerging abnormalities may provide novel approaches to treat the acute episode, avoid recurrences, and prevent major adverse cardiovascular events.PMID:37190802 | DOI:10.2174/1874471016666230515142106 (Source: Current Radiopharmaceuticals)
Source: Current Radiopharmaceuticals - May 16, 2023 Category: Radiology Authors: Stelvio Sestini Angela Coppola Manjola Dona Anna Lisa Martini Elisa Tardelli Giulia Montelatici Iashar Laghai Angela Arena Giulia Carli Francesco Pestelli Bianca Maraviglia Giulia Bruni Christian Mazzeo Luca Fedeli Luigi Mansi Source Type: research