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Unraveling the Role of Neuroligin3 in Autism Spectrum Disorders: Pathophysiological Insights and Targeted Therapies
CNS Neurol Disord Drug Targets. 2023 Jul 27. doi: 10.2174/1871527323666230727102244. Online ahead of print.ABSTRACTAutism Spectrum Disorder is a neurodevelopmental disorder characterized by impaired social and communication skills, repetitive behaviors, and/or restricted interests with a prevalence of as high as 1% of children. Autism spectrum has strongly associated with genetic factors and exhibits wide clinical and heterogeneous genetic architecture. Most genes associated with Autism are involved in neuronal and synaptic development. The neuroligin3, the sex-linked gene on the X chromosome, was the first gene to be asso...
Source: CNS and Neurological Disorders Drug Targets - July 27, 2023 Category: Drugs & Pharmacology Authors: Fatima Azzahrae El Yacoubi Mohamed Oukabli Azeddine Ibrahimi Hassan Kisra Mounia Bensaid Source Type: research

Unraveling the Role of Neuroligin3 in Autism Spectrum Disorders: Pathophysiological Insights and Targeted Therapies
CNS Neurol Disord Drug Targets. 2023 Jul 27. doi: 10.2174/1871527323666230727102244. Online ahead of print.ABSTRACTAutism Spectrum Disorder is a neurodevelopmental disorder characterized by impaired social and communication skills, repetitive behaviors, and/or restricted interests with a prevalence of as high as 1% of children. Autism spectrum has strongly associated with genetic factors and exhibits wide clinical and heterogeneous genetic architecture. Most genes associated with Autism are involved in neuronal and synaptic development. The neuroligin3, the sex-linked gene on the X chromosome, was the first gene to be asso...
Source: CNS and Neurological Disorders Drug Targets - July 27, 2023 Category: Drugs & Pharmacology Authors: Fatima Azzahrae El Yacoubi Mohamed Oukabli Azeddine Ibrahimi Hassan Kisra Mounia Bensaid Source Type: research

Unraveling the Role of Neuroligin3 in Autism Spectrum Disorders: Pathophysiological Insights and Targeted Therapies
CNS Neurol Disord Drug Targets. 2023 Jul 27. doi: 10.2174/1871527323666230727102244. Online ahead of print.ABSTRACTAutism Spectrum Disorder is a neurodevelopmental disorder characterized by impaired social and communication skills, repetitive behaviors, and/or restricted interests with a prevalence of as high as 1% of children. Autism spectrum has strongly associated with genetic factors and exhibits wide clinical and heterogeneous genetic architecture. Most genes associated with Autism are involved in neuronal and synaptic development. The neuroligin3, the sex-linked gene on the X chromosome, was the first gene to be asso...
Source: CNS and Neurological Disorders Drug Targets - July 27, 2023 Category: Drugs & Pharmacology Authors: Fatima Azzahrae El Yacoubi Mohamed Oukabli Azeddine Ibrahimi Hassan Kisra Mounia Bensaid Source Type: research

Unraveling the Role of Neuroligin3 in Autism Spectrum Disorders: Pathophysiological Insights and Targeted Therapies
CNS Neurol Disord Drug Targets. 2023 Jul 27. doi: 10.2174/1871527323666230727102244. Online ahead of print.ABSTRACTAutism Spectrum Disorder is a neurodevelopmental disorder characterized by impaired social and communication skills, repetitive behaviors, and/or restricted interests with a prevalence of as high as 1% of children. Autism spectrum has strongly associated with genetic factors and exhibits wide clinical and heterogeneous genetic architecture. Most genes associated with Autism are involved in neuronal and synaptic development. The neuroligin3, the sex-linked gene on the X chromosome, was the first gene to be asso...
Source: CNS and Neurological Disorders Drug Targets - July 27, 2023 Category: Drugs & Pharmacology Authors: Fatima Azzahrae El Yacoubi Mohamed Oukabli Azeddine Ibrahimi Hassan Kisra Mounia Bensaid Source Type: research

Unraveling the Role of Neuroligin3 in Autism Spectrum Disorders: Pathophysiological Insights and Targeted Therapies
CNS Neurol Disord Drug Targets. 2023 Jul 27. doi: 10.2174/1871527323666230727102244. Online ahead of print.ABSTRACTAutism Spectrum Disorder is a neurodevelopmental disorder characterized by impaired social and communication skills, repetitive behaviors, and/or restricted interests with a prevalence of as high as 1% of children. Autism spectrum has strongly associated with genetic factors and exhibits wide clinical and heterogeneous genetic architecture. Most genes associated with Autism are involved in neuronal and synaptic development. The neuroligin3, the sex-linked gene on the X chromosome, was the first gene to be asso...
Source: CNS and Neurological Disorders Drug Targets - July 27, 2023 Category: Drugs & Pharmacology Authors: Fatima Azzahrae El Yacoubi Mohamed Oukabli Azeddine Ibrahimi Hassan Kisra Mounia Bensaid Source Type: research

Unraveling the Role of Neuroligin3 in Autism Spectrum Disorders: Pathophysiological Insights and Targeted Therapies
CNS Neurol Disord Drug Targets. 2023 Jul 27. doi: 10.2174/1871527323666230727102244. Online ahead of print.ABSTRACTAutism Spectrum Disorder is a neurodevelopmental disorder characterized by impaired social and communication skills, repetitive behaviors, and/or restricted interests with a prevalence of as high as 1% of children. Autism spectrum has strongly associated with genetic factors and exhibits wide clinical and heterogeneous genetic architecture. Most genes associated with Autism are involved in neuronal and synaptic development. The neuroligin3, the sex-linked gene on the X chromosome, was the first gene to be asso...
Source: CNS and Neurological Disorders Drug Targets - July 27, 2023 Category: Drugs & Pharmacology Authors: Fatima Azzahrae El Yacoubi Mohamed Oukabli Azeddine Ibrahimi Hassan Kisra Mounia Bensaid Source Type: research

Unraveling the Role of Neuroligin3 in Autism Spectrum Disorders: Pathophysiological Insights and Targeted Therapies
CNS Neurol Disord Drug Targets. 2023 Jul 27. doi: 10.2174/1871527323666230727102244. Online ahead of print.ABSTRACTAutism Spectrum Disorder is a neurodevelopmental disorder characterized by impaired social and communication skills, repetitive behaviors, and/or restricted interests with a prevalence of as high as 1% of children. Autism spectrum has strongly associated with genetic factors and exhibits wide clinical and heterogeneous genetic architecture. Most genes associated with Autism are involved in neuronal and synaptic development. The neuroligin3, the sex-linked gene on the X chromosome, was the first gene to be asso...
Source: CNS and Neurological Disorders Drug Targets - July 27, 2023 Category: Drugs & Pharmacology Authors: Fatima Azzahrae El Yacoubi Mohamed Oukabli Azeddine Ibrahimi Hassan Kisra Mounia Bensaid Source Type: research

Unraveling the Role of Neuroligin3 in Autism Spectrum Disorders: Pathophysiological Insights and Targeted Therapies
CNS Neurol Disord Drug Targets. 2023 Jul 27. doi: 10.2174/1871527323666230727102244. Online ahead of print.ABSTRACTAutism Spectrum Disorder is a neurodevelopmental disorder characterized by impaired social and communication skills, repetitive behaviors, and/or restricted interests with a prevalence of as high as 1% of children. Autism spectrum has strongly associated with genetic factors and exhibits wide clinical and heterogeneous genetic architecture. Most genes associated with Autism are involved in neuronal and synaptic development. The neuroligin3, the sex-linked gene on the X chromosome, was the first gene to be asso...
Source: CNS and Neurological Disorders Drug Targets - July 27, 2023 Category: Drugs & Pharmacology Authors: Fatima Azzahrae El Yacoubi Mohamed Oukabli Azeddine Ibrahimi Hassan Kisra Mounia Bensaid Source Type: research

Unraveling the Role of Neuroligin3 in Autism Spectrum Disorders: Pathophysiological Insights and Targeted Therapies
CNS Neurol Disord Drug Targets. 2023 Jul 27. doi: 10.2174/1871527323666230727102244. Online ahead of print.ABSTRACTAutism Spectrum Disorder is a neurodevelopmental disorder characterized by impaired social and communication skills, repetitive behaviors, and/or restricted interests with a prevalence of as high as 1% of children. Autism spectrum has strongly associated with genetic factors and exhibits wide clinical and heterogeneous genetic architecture. Most genes associated with Autism are involved in neuronal and synaptic development. The neuroligin3, the sex-linked gene on the X chromosome, was the first gene to be asso...
Source: CNS and Neurological Disorders Drug Targets - July 27, 2023 Category: Drugs & Pharmacology Authors: Fatima Azzahrae El Yacoubi Mohamed Oukabli Azeddine Ibrahimi Hassan Kisra Mounia Bensaid Source Type: research

Towards a Systemic Concept of the Brain Ishemia Stroke: Monte Carlo Driven in Silico Model
CONCLUSION: For the first time, a mathematical model has been constructed that allows us to represent the spatial dynamics of the development of the affected area in ischemic stroke of the brain, taking into account neurovascular units as single morphofunctional structures.PMID:37469160 | DOI:10.2174/1871527322666230719111903 (Source: CNS and Neurological Disorders Drug Targets)
Source: CNS and Neurological Disorders Drug Targets - July 20, 2023 Category: Drugs & Pharmacology Authors: Valentin V Fursov Alexander V Ananiev Dmitry A Kuznetsov Source Type: research

Towards a Systemic Concept of the Brain Ishemia Stroke: Monte Carlo Driven in Silico Model
CONCLUSION: For the first time, a mathematical model has been constructed that allows us to represent the spatial dynamics of the development of the affected area in ischemic stroke of the brain, taking into account neurovascular units as single morphofunctional structures.PMID:37469160 | DOI:10.2174/1871527322666230719111903 (Source: CNS and Neurological Disorders Drug Targets)
Source: CNS and Neurological Disorders Drug Targets - July 20, 2023 Category: Drugs & Pharmacology Authors: Valentin V Fursov Alexander V Ananiev Dmitry A Kuznetsov Source Type: research

Towards a Systemic Concept of the Brain Ishemia Stroke: Monte Carlo Driven in Silico Model
CONCLUSION: For the first time, a mathematical model has been constructed that allows us to represent the spatial dynamics of the development of the affected area in ischemic stroke of the brain, taking into account neurovascular units as single morphofunctional structures.PMID:37469160 | DOI:10.2174/1871527322666230719111903 (Source: CNS and Neurological Disorders Drug Targets)
Source: CNS and Neurological Disorders Drug Targets - July 20, 2023 Category: Drugs & Pharmacology Authors: Valentin V Fursov Alexander V Ananiev Dmitry A Kuznetsov Source Type: research

Towards a Systemic Concept of the Brain Ishemia Stroke: Monte Carlo Driven in Silico Model
CONCLUSION: For the first time, a mathematical model has been constructed that allows us to represent the spatial dynamics of the development of the affected area in ischemic stroke of the brain, taking into account neurovascular units as single morphofunctional structures.PMID:37469160 | DOI:10.2174/1871527322666230719111903 (Source: CNS and Neurological Disorders Drug Targets)
Source: CNS and Neurological Disorders Drug Targets - July 20, 2023 Category: Drugs & Pharmacology Authors: Valentin V Fursov Alexander V Ananiev Dmitry A Kuznetsov Source Type: research

Towards a Systemic Concept of the Brain Ishemia Stroke: Monte Carlo Driven in Silico Model
CONCLUSION: For the first time, a mathematical model has been constructed that allows us to represent the spatial dynamics of the development of the affected area in ischemic stroke of the brain, taking into account neurovascular units as single morphofunctional structures.PMID:37469160 | DOI:10.2174/1871527322666230719111903 (Source: CNS and Neurological Disorders Drug Targets)
Source: CNS and Neurological Disorders Drug Targets - July 20, 2023 Category: Drugs & Pharmacology Authors: Valentin V Fursov Alexander V Ananiev Dmitry A Kuznetsov Source Type: research

Towards a Systemic Concept of the Brain Ishemia Stroke: Monte Carlo Driven in Silico Model
CONCLUSION: For the first time, a mathematical model has been constructed that allows us to represent the spatial dynamics of the development of the affected area in ischemic stroke of the brain, taking into account neurovascular units as single morphofunctional structures.PMID:37469160 | DOI:10.2174/1871527322666230719111903 (Source: CNS and Neurological Disorders Drug Targets)
Source: CNS and Neurological Disorders Drug Targets - July 20, 2023 Category: Drugs & Pharmacology Authors: Valentin V Fursov Alexander V Ananiev Dmitry A Kuznetsov Source Type: research