Unique Aspects of Asthma in Women
There are many unique aspects of asthma in women. Compared with men, women go through several hormonal stages over the life span —childhood, menarche, reproductive years, pregnancy, menopause, and postmenopause—and each affects asthma. Onset of asthma in women differs from men. Asthma in women is more often associated with obesity and women are over-represented among patients with severe asthma, including those being pres cribed biologic therapies. Asthma affects fertility and pregnancy, and female hormone replacement therapy has been found to affect asthma onset as well as asthma severity. We explore the unique aspect...
Source: Clinics in Chest Medicine - August 3, 2021 Category: Respiratory Medicine Authors: Casper Tidemandsen, Erik Soeren Halvard Hansen, Soeren Malte Rasmussen, Charlotte Suppli Ulrik, Vibeke Backer Source Type: research
Challenges Faced by Women with Cystic Fibrosis
Women with cystic fibrosis (CF) face several unaddressed concerns related to their health. These areas of concern include explanations and guidance on a sex disparity in outcomes, timing of puberty, effects of contraception, prevalence of infertility and impact of pregnancy, and prevention of urinary incontinence and osteoporosis. These understudied topics leave women with numerous unanswered questions about how to manage sexual and reproductive health in the setting of CF. Because people with CF are living longer and healthier lives, there is an increasing awareness of these important aspects of care and multiple ongoing ...
Source: Clinics in Chest Medicine - August 3, 2021 Category: Respiratory Medicine Authors: Raksha Jain, Traci M. Kazmerski, Moira L. Aitken, Natalie West, Alexandra Wilson, Kubra M. Bozkanat, Kristina Montemayor, Karen von Berg, Jacqui Sjoberg, Maddie Poranski, Jennifer L. Taylor-Cousar Source Type: research
Interstitial Lung Diseases and the Impact of Gender
Interstitial lung diseases encompass an amalgamated group of heterogeneous lung disorders, characterized by variable clinical and radiologic patterns. Despite an increase in our knowledge, pathogenesis of interstitial lung diseases remains largely unknown. Experimental evidence on the role of sex hormones in lung development and epidemiologic associations of gender differences with interstitial lung diseases prevalence fueled studies investigating the role of gender and sex hormones in the pathogenesis and treatment of pulmonary fibrosis. This review summarizes experimental and clinical data for the impact of gender and se...
Source: Clinics in Chest Medicine - August 3, 2021 Category: Respiratory Medicine Authors: Theodoros Karampitsakos, Ourania Papaioannou, Matthaios Katsaras, Fotios Sampsonas, Argyris Tzouvelekis Source Type: research
Gender Differences in Critical Illness and Critical Care Research
Gender is emerging as a factor that may impact the trajectory of critical illness; clinical trials in critical care have largely enrolled men with little attention to equal distribution of sexes. Distribution of admission to the intensive care unit and utilization of resources differs by gender. Sex hormones are thought to impact the course of critical illness. Management and outcomes in sepsis and acute respiratory distress syndrome have been demonstrated to differ by gender as well as in pregnancy. Outcomes of critically ill patients may be impacted by gender. (Source: Clinics in Chest Medicine)
Source: Clinics in Chest Medicine - August 3, 2021 Category: Respiratory Medicine Authors: Tasnim I. Lat, Meghan K. McGraw, Heath D. White Source Type: research
Pharmacology Considerations in Women in Lung Disease and Critical Care
This article provides an overview of sex differences in drug pharmacokinetics, with a focus on pharmacology in respiratory disease and in critical illness, as well as differences in pharmacokinetics throughout the female life cycle, with regard to pregnancy and menopause. (Source: Clinics in Chest Medicine)
Source: Clinics in Chest Medicine - August 3, 2021 Category: Respiratory Medicine Authors: Claire C. Eng, Mojdeh S. Heavner Source Type: research
Lung Diseases Unique to Women
The differences in the respiratory system between women and men begin in utero. Biologic sex plays a critical role in fetal development, airway anatomy, inhalational exposures, and inhaled particle deposition of the respiratory system, thus leading to differences in risk for disease, as well as clinical manifestations, morbidity, and mortality. In this article, we focus on those respiratory diseases unique to females: lymphangioleiomyomatosis and thoracic endometriosis syndrome (Source: Clinics in Chest Medicine)
Source: Clinics in Chest Medicine - August 3, 2021 Category: Respiratory Medicine Authors: Rachel N. Criner, Abdullah Al-abcha, Allison A. Lambert, MeiLan K. Han Source Type: research
Differences Between Men and Women with Chronic Obstructive Pulmonary Disease
There are many differences between men and women in risk factor vulnerability and impact, symptom development, presentation, clinical manifestations, and outcomes of chronic obstructive pulmonary disease (COPD). These differences have been inadequately explored, which is of particular concern in view of the delay in diagnosis and treatment that occurs for both men and women, and the need to use all therapies in a targeted and tailored way for best clinical gain and least harm. Women are generally underrepresented in randomized trials, as are non –tobacco-related phenotypes of COPD. We must garner the information availabl...
Source: Clinics in Chest Medicine - August 3, 2021 Category: Respiratory Medicine Authors: Christine Jenkins Source Type: research
Gender and Respiratory Disease
There is increasing evidence that sex and gender impact the incidence, susceptibility, and severity of lung diseases. Sex has been shown to influence lung development and physiology. The 3 most common lung diseases in women are asthma, chronic obstructive pulmonary disease (COPD), and lung cancer. In addition to the biological differences attributed to sex, there are gender differences in rates of diagnosis of lung disease and treatments prescribed. (Source: Clinics in Chest Medicine)
Source: Clinics in Chest Medicine - August 3, 2021 Category: Respiratory Medicine Authors: Margaret A. Pisani Tags: Preface Source Type: research
Gender and Respiratory Disease
CLINICS IN CHEST MEDICINE (Source: Clinics in Chest Medicine)
Source: Clinics in Chest Medicine - August 3, 2021 Category: Respiratory Medicine Authors: Margaret A. Pisani Source Type: research
Copyright
ELSEVIER (Source: Clinics in Chest Medicine)
Source: Clinics in Chest Medicine - August 3, 2021 Category: Respiratory Medicine Source Type: research
Contributors
MARGARET A. PISANI, MD, MPH (Source: Clinics in Chest Medicine)
Source: Clinics in Chest Medicine - August 3, 2021 Category: Respiratory Medicine Source Type: research
Contents
Margaret A. Pisani (Source: Clinics in Chest Medicine)
Source: Clinics in Chest Medicine - August 3, 2021 Category: Respiratory Medicine Source Type: research
Forthcoming Issues
Pleural Disease (Source: Clinics in Chest Medicine)
Source: Clinics in Chest Medicine - August 3, 2021 Category: Respiratory Medicine Source Type: research
Interstitial Lung Disease in 2020
Interstitial lung diseases (ILDs) are heterogenous and complex chronic lung diseases that even today are challenging to diagnose and classify. The terminology and mechanistic understanding of specific ILDs have evolved substantially over the last centuries and decades, and clinicians, pathologists, radiologists, and researchers are continuously working to untangle the various ILDs of differing causes. Despite many drawbacks and negative clinical trials, the unremitting work of ILD researchers have resulted in great therapeutic successes over the last decade. In this chapter, the authors present historical aspects of ILD an...
Source: Clinics in Chest Medicine - May 21, 2021 Category: Respiratory Medicine Authors: Sabina A. Guler, Tamera J. Corte Source Type: research
Diagnostic Classification of Interstitial Lung Disease in Clinical Practice
This article reviews a pragmatic approach to ILD diagnosis and classification, focusing on diagnostic tools and strategies that are used to separate different subtypes and identify the most appropriate management. We discuss the evolution of ILD classification and the contemporary approach that integrates routinely used diagnostic tools in a multidisciplinary discussion. We highlight the increasing importance of taking a multipronged approach to ILD classification that reflects the recent emphasis on disease behavior while also considering etiopathogenesis and morphologic features. (Source: Clinics in Chest Medicine)
Source: Clinics in Chest Medicine - May 21, 2021 Category: Respiratory Medicine Authors: Ayodeji Adegunsoye, Christopher J. Ryerson Source Type: research
