Sleep Deficiency and Health
CLINICS IN CHEST MEDICINE (Source: Clinics in Chest Medicine)
Source: Clinics in Chest Medicine - June 1, 2022 Category: Respiratory Medicine Authors: MELISSA P. KNAUERT Source Type: research
Copyright
ELSEVIER (Source: Clinics in Chest Medicine)
Source: Clinics in Chest Medicine - June 1, 2022 Category: Respiratory Medicine Source Type: research
Contributors
MELISSA P. KNAUERT, MD, PhD (Source: Clinics in Chest Medicine)
Source: Clinics in Chest Medicine - June 1, 2022 Category: Respiratory Medicine Source Type: research
Contents
Melissa P. Knauert (Source: Clinics in Chest Medicine)
Source: Clinics in Chest Medicine - June 1, 2022 Category: Respiratory Medicine Source Type: research
Forthcoming Issues
Critical Care (Source: Clinics in Chest Medicine)
Source: Clinics in Chest Medicine - June 1, 2022 Category: Respiratory Medicine Source Type: research
COVID-19 and the Transformation of Intensive Care Unit Telemedicine
The concept of telecritical care has evolved over several decades. ICU Telemedicine providers using both the hub-and-spoke ICU telemedicine center and consultative service delivery models offered their services during the COVID-19 pandemic. Telemedicine center responses were more efficient, timely, and widely used than those of the consultative model. Bedside nurses, physicians, nurse practitioners, physician assistants, and respiratory therapists incorporated the use of ICU telemedicine tools into their practices and more frequently requested critical care specialist telemedicine support. (Source: Clinics in Chest Medicine)
Source: Clinics in Chest Medicine - May 12, 2022 Category: Respiratory Medicine Authors: Eric W. Cucchi, Scott E. Kopec, Craig M. Lilly Source Type: research
COVID-19 and the transformation of ICU Telemedicine
The concept of telecritical care has evolved over several decades.1,2 ICU Telemedicine providers using both the hub-and spoke ICU telemedicine center and consultative service delivery models offered their services during the COVID-19 pandemic. Telemedicine center responses were more efficient, timely, and widely employed than those of consultative model. Bedside nurses, physicians, nurse practitioners, physician assistants, and respiratory therapists incorporated the use of ICU telemedicine tools into their practices and more frequently requested critical care specialist telemedicine support. (Source: Clinics in Chest Medicine)
Source: Clinics in Chest Medicine - May 12, 2022 Category: Respiratory Medicine Authors: Eric W. Cucchi, Scott E. Kopec, Craig M. Lilly Source Type: research
Caring for the Critically Ill Patient with COVID-19
The COVID-19 pandemic has resulted in unprecedented numbers of critically ill patients. Critical care providers have been challenged to increase the capacity for critical care, prevent the spread of SARS-CoV-2 in hospitals, determine the optimal treatment approaches for patients with critical COVID-19, and to design and implement systems for fair allocation of scarce life-saving resources when capacity is exhausted. The global burden of COVID-19 highlighted disparities, across geographic regions and among minority patient populations. Faced with a novel pathogen, critical care providers grappled with the extent to which co...
Source: Clinics in Chest Medicine - April 19, 2022 Category: Respiratory Medicine Authors: Matthew K. Hensley, Hallie C. Prescott Source Type: research
Diagnosis and Evaluation of Bronchiectasis
Bronchiectasis is characterized by inflammation and abnormal dilatation of the airways secondary to various etiologies. A diagnosis of bronchiectasis requires that both radiological and clinical features are present. Determination of the etiology of bronchiectasis is important to allow specific treatment and should be guided by clinical features. The prognosis of bronchiectasis is highly variable, with severe cases suffering frequent exacerbations and hospitalizations, debilitating symptoms, and elevated mortality. Treatment is demanding, but adherence to treatment is associated with improved outcomes and should be assesse...
Source: Clinics in Chest Medicine - February 28, 2022 Category: Respiratory Medicine Authors: Raya Cohen, Michal Shteinberg Source Type: research
Microbiology and the Microbiome in Bronchiectasis
The microbiology in bronchiectasis has been historically defined by culture-based analysis of the airway microbiome and to date has largely focused on the detection and eradication of specific bacterial pathogens. Although central to our current understanding of disease, microbial culture alone masks the holistic complexity of the microbiome and does not account for potential microbial interactions that define specific clinical phenotypes such as frequent exacerbators. Advances in next-generation sequencing including their analytical technologies can further complement and build upon our current understanding of the microb...
Source: Clinics in Chest Medicine - February 28, 2022 Category: Respiratory Medicine Authors: Miche ál Mac Aogáin, Sanjay H. Chotirmall Source Type: research
The Pathogenesis of Bronchiectasis
Bronchiectasis is a condition defined by permanently dilated airways and characterized by chronic cough and sputum and in many patients, recurrent exacerbations. Bronchiectasis is a heterogeneous condition, with numerous underlying risk factors and initiating conditions. These factors share in common the ability to impair the mechanisms by which the airways are protected from inflammatory or infectious insults. These underlying factors result in chronic bacterial infection of the airways, inciting a host inflammatory response in which the airways are the collateral damage. The damaged airways are unable to clear the infect...
Source: Clinics in Chest Medicine - February 28, 2022 Category: Respiratory Medicine Authors: Mark L. Metersky, Alan F. Barker Source Type: research
Radiology of Bronchiectasis
Bronchiectasis is a radiological diagnosis made using computed tomographic (CT) imaging. Although visual CT assessment is necessary for the diagnosis of bronchiectasis, visual assessment of disease severity and progression is challenging. Computer tools offer the potential to improve the characterization of lung damage in patients with bronchiectasis. Newer imaging techniques such as MRI with hyperpolarized gas inhalation have the potential to identify early forms of disease and are without the constraints of requiring ionizing radiation exposure. (Source: Clinics in Chest Medicine)
Source: Clinics in Chest Medicine - February 28, 2022 Category: Respiratory Medicine Authors: Ashkan Pakzad, Joseph Jacob Source Type: research
Bronchiectasis and Chronic Obstructive Pulmonary Disease Overlap Syndrome
The bronchiectasis and chronic obstructive pulmonary disease (COPD) overlap syndrome (BCOS) is increasingly recognized. BCOS is associated with poorer outcomes and increased mortality than in either disease alone. In the following article, the authors discuss why COPD and bronchiectasis might coexist, the radiological issues in diagnosing bronchiectasis in COPD, the understanding of prevalence and the factors that impact this, mortality and morbidity, microbiology associations, and the impact BCOS has on investigations and management. (Source: Clinics in Chest Medicine)
Source: Clinics in Chest Medicine - February 28, 2022 Category: Respiratory Medicine Authors: Ruth Sobala, Anthony De Soyza Source Type: research
Bronchiectasis in Childhood
Bronchiectasis is one of the diagnostic entities in the spectrum of pediatric chronic wet cough, causing significant morbidity and mortality. The pathobiology involves a vicious cycle of repeated infections, airway inflammation, dysregulated immunity, and tissue remodeling, resulting in impaired airway clearance, destruction of structural elements within the bronchial wall causing them to become dilated, and small-airway obstruction. Pediatric pathobiological studies are lacking, although there are recent data on the role of antibiotics in treating and preventing exacerbations. The focus has moved to understanding ways to ...
Source: Clinics in Chest Medicine - February 28, 2022 Category: Respiratory Medicine Authors: Vikas Goyal, Anne B. Chang Source Type: research
Nontuberculous Mycobacteria
Patients with bronchiectasis are at high risk for nontuberculous mycobacteria (NTM) disease and suspicion should be high in the setting of worsening respiratory symptoms and disease progression on imaging. Meeting the case definition for NTM disease does not equal a decision to treat; risk and benefits of therapy should be discussed with patients. When treatment is initiated, a multidrug regimen should be used and selected based on susceptibility testing from a reliable laboratory. Monotherapy or macrolide-fluoroquinolone dual therapy should never be used. After discontinuation of therapy, ongoing mycobacterial sputum cult...
Source: Clinics in Chest Medicine - February 28, 2022 Category: Respiratory Medicine Authors: Cara D. Varley, Kevin L. Winthrop Source Type: research
