LONP1 ameliorates liver injury and improves gluconeogenesis dysfunction in acute-on-chronic liver failure
CONCLUSION: We demonstrated that gluconeogenesis dysfunction exists in ACLF, and LONP1 could ameliorate liver injury and improve gluconeogenic dysfunction, which would provide a promising therapeutic target for patients with ACLF.PMID:38184784 | DOI:10.1097/CM9.0000000000002969 (Source: Chinese Medical Journal)
Source: Chinese Medical Journal - January 7, 2024 Category: General Medicine Authors: Muchen Wu Jing Wu Kai Liu Minjie Jiang Fang Xie Xuehong Yin Jushan Wu Qinghua Meng Source Type: research

LONP1 ameliorates liver injury and improves gluconeogenesis dysfunction in acute-on-chronic liver failure
CONCLUSION: We demonstrated that gluconeogenesis dysfunction exists in ACLF, and LONP1 could ameliorate liver injury and improve gluconeogenic dysfunction, which would provide a promising therapeutic target for patients with ACLF.PMID:38184784 | DOI:10.1097/CM9.0000000000002969 (Source: Chinese Medical Journal)
Source: Chinese Medical Journal - January 7, 2024 Category: General Medicine Authors: Muchen Wu Jing Wu Kai Liu Minjie Jiang Fang Xie Xuehong Yin Jushan Wu Qinghua Meng Source Type: research

Circulating biomarker- and magnetic resonance-based nomogram predicting long-term outcomes in dilated cardiomyopathy
CONCLUSIONS: We established and validated a circulating biomarker- and CMRI-based nomogram that could provide a personalized prediction of ACM/HTx for DCM patients, which might help risk stratification and decision-making in clinical practice.PMID:38178323 | PMC:PMC10766284 | DOI:10.1097/CM9.0000000000002688 (Source: Chinese Medical Journal)
Source: Chinese Medical Journal - January 5, 2024 Category: General Medicine Authors: Yupeng Liu Wenyao Wang Jingjing Song Jiancheng Wang Yi Fu Yida Tang Source Type: research

Promotion effect of FOXCUT as a microRNA sponge for miR-24-3p on progression in triple-negative breast cancer through the p38 MAPK signaling pathway
CONCLUSION: Collectively, this research revealed a novel FOXCUT/miR-24-3p/p38 axis that affected breast cancer progression and suggested that the lncRNA FOXCUT could be a diagnostic marker and therapeutic target for breast cancer.PMID:38178324 | PMC:PMC10766298 | DOI:10.1097/CM9.0000000000002700 (Source: Chinese Medical Journal)
Source: Chinese Medical Journal - January 5, 2024 Category: General Medicine Authors: Xiafei Yu Fangze Qian Xiaoqiang Zhang Yanhui Zhu Gao He Junzhe Yang Xian Wu Yi Zhou Li Shen Xiaoyue Shi Hongfei Zhang Xiao'an Liu Source Type: research

Impact of peri-operative venous thromboembolism on survival in patients with endometrial clear cell carcinoma: A 10-year single-institution retrospective study
Chin Med J (Engl). 2024 Jan 5. doi: 10.1097/CM9.0000000000002951. Online ahead of print.NO ABSTRACTPMID:38180807 | DOI:10.1097/CM9.0000000000002951 (Source: Chinese Medical Journal)
Source: Chinese Medical Journal - January 5, 2024 Category: General Medicine Authors: Xuesong Ding Yuan Li Dongyan Cao Xirun Wan Ming Wu Lingya Pan Junjun Yang Yang Xiang Source Type: research