LONP1 ameliorates liver injury and improves gluconeogenesis dysfunction in acute-on-chronic liver failure

CONCLUSION: We demonstrated that gluconeogenesis dysfunction exists in ACLF, and LONP1 could ameliorate liver injury and improve gluconeogenic dysfunction, which would provide a promising therapeutic target for patients with ACLF.PMID:38184784 | DOI:10.1097/CM9.0000000000002969

Source: Chinese Medical Journal - January 7, 2024 Category: General Medicine Authors: Muchen Wu Jing Wu Kai Liu Minjie Jiang Fang Xie Xuehong Yin Jushan Wu Qinghua Meng Source Type: research