Effect of GnRH analogs in advanced male breast cancer: 10-year experience from the Henan Breast Cancer Center and literature review
Chin Med J (Engl). 2024 Mar 6. doi: 10.1097/CM9.0000000000003005. Online ahead of print.NO ABSTRACTPMID:38445362 | DOI:10.1097/CM9.0000000000003005 (Source: Chinese Medical Journal)
Source: Chinese Medical Journal - March 6, 2024 Category: General Medicine Authors: Mengwei Zhang Huimin Lv Limin Niu Zhenzhen Liu Huiai Zeng Shengnan Zhao Jing Wang Huihui Sun Min Yan Source Type: research
Role of mitochondrial dysfunction in kidney disease: Insights from the cGAS-STING signaling pathway
Chin Med J (Engl). 2024 Mar 6. doi: 10.1097/CM9.0000000000003022. Online ahead of print.ABSTRACTOver the past decade, mitochondrial dysfunction has been investigated as a key contributor to acute and chronic kidney disease. However, the precise molecular mechanisms linking mitochondrial damage to kidney disease remain elusive. The recent insights into the cyclic guanosine monophosphate-adenosine monophosphate (GMP-AMP) synthetase (cGAS)-stimulator of interferon gene (STING) signaling pathway have revealed its involvement in many renal diseases. One of these findings is that mitochondrial DNA (mtDNA) induces inflammatory re...
Source: Chinese Medical Journal - March 6, 2024 Category: General Medicine Authors: Lu Li Fei Liu Chunyue Feng Zhenjie Chen Nan Zhang Jianhua Mao Source Type: research
A novel intracoronary hypothermia device reduces myocardial reperfusion injury in pigs
CONCLUSIONS: The SICH device safely and effectively reduced the infarct size and improved heart function in a pig model of MI/R. These beneficial effects indicate the clinical potential of SICH for treatment of myocardial reperfusion injury.PMID:38445387 | DOI:10.1097/CM9.0000000000003033 (Source: Chinese Medical Journal)
Source: Chinese Medical Journal - March 6, 2024 Category: General Medicine Authors: Zhiqiang Pei Jin Qiu Yongchao Zhao Shuai Song Rui Wang Wei Luo Xingxing Cai Bin Liu Han Chen Jiasheng Yin Xinyu Weng Yizhe Wu Chenguang Li Li Shen Junbo Ge Source Type: research
Therapeutic role of miR-26a on cardiaorenal injury in mice model of angiotensin-II induced chronic kidney disease through inhibition of LIMS1/ILK pathway
CONCLUSIONS: Our findings suggest that miR-26a could be a promising therapeutic target for the treatment of cardiorenal injury in CKD. This is attributed to its ability to regulate the LIMS1/ILK signaling pathway, which represents a common molecular mechanism in both heart and kidney tissues.PMID:38445356 | DOI:10.1097/CM9.0000000000002978 (Source: Chinese Medical Journal)
Source: Chinese Medical Journal - March 6, 2024 Category: General Medicine Authors: Weijie Ni Yajie Zhao Jinxin Shen Qing Yin Yao Wang Zuolin Li Taotao Tang Yi Wen Yilin Zhang Wei Jiang Liangyunzi Jiang Jinxuan Wei Weihua Gan Aiqing Zhang Xiaoyu Zhou Bin Wang Bi-Cheng Liu Source Type: research
Somatic CDKN2A copy number variations are associated with the prognosis of esophageal squamous cell dysplasia
CONCLUSION: The results indicated that CDKN2A SCNVs are associated with the prognosis of ESCdys and may serve as potential biomarkers for risk stratification.PMID:38445358 | DOI:10.1097/CM9.0000000000002982 (Source: Chinese Medical Journal)
Source: Chinese Medical Journal - March 6, 2024 Category: General Medicine Authors: Zhiyuan Fan Jing Zhou Yuan Tian Yu Qin Zhaojun Liu Liankun Gu Sanford M Dawsey Wenqiang Wei Dajun Deng Source Type: research
Effect of GnRH analogs in advanced male breast cancer: 10-year experience from the Henan Breast Cancer Center and literature review
Chin Med J (Engl). 2024 Mar 6. doi: 10.1097/CM9.0000000000003005. Online ahead of print.NO ABSTRACTPMID:38445362 | DOI:10.1097/CM9.0000000000003005 (Source: Chinese Medical Journal)
Source: Chinese Medical Journal - March 6, 2024 Category: General Medicine Authors: Mengwei Zhang Huimin Lv Limin Niu Zhenzhen Liu Huiai Zeng Shengnan Zhao Jing Wang Huihui Sun Min Yan Source Type: research
Role of mitochondrial dysfunction in kidney disease: Insights from the cGAS-STING signaling pathway
Chin Med J (Engl). 2024 Mar 6. doi: 10.1097/CM9.0000000000003022. Online ahead of print.ABSTRACTOver the past decade, mitochondrial dysfunction has been investigated as a key contributor to acute and chronic kidney disease. However, the precise molecular mechanisms linking mitochondrial damage to kidney disease remain elusive. The recent insights into the cyclic guanosine monophosphate-adenosine monophosphate (GMP-AMP) synthetase (cGAS)-stimulator of interferon gene (STING) signaling pathway have revealed its involvement in many renal diseases. One of these findings is that mitochondrial DNA (mtDNA) induces inflammatory re...
Source: Chinese Medical Journal - March 6, 2024 Category: General Medicine Authors: Lu Li Fei Liu Chunyue Feng Zhenjie Chen Nan Zhang Jianhua Mao Source Type: research
A novel intracoronary hypothermia device reduces myocardial reperfusion injury in pigs
CONCLUSIONS: The SICH device safely and effectively reduced the infarct size and improved heart function in a pig model of MI/R. These beneficial effects indicate the clinical potential of SICH for treatment of myocardial reperfusion injury.PMID:38445387 | DOI:10.1097/CM9.0000000000003033 (Source: Chinese Medical Journal)
Source: Chinese Medical Journal - March 6, 2024 Category: General Medicine Authors: Zhiqiang Pei Jin Qiu Yongchao Zhao Shuai Song Rui Wang Wei Luo Xingxing Cai Bin Liu Han Chen Jiasheng Yin Xinyu Weng Yizhe Wu Chenguang Li Li Shen Junbo Ge Source Type: research
Development of a droplet digital polymerase chain reaction assay for the sensitive detection of total and integrated HIV-1 DNA
CONCLUSIONS: This ddPCR assay can quantify total HIV DNA and integrated HIV DNA efficiently with robustness and sensitivity. It can be readily adapted for measuring HIV DNA with non-B clades, and it could be beneficial for testing in clinical trials.PMID:38433332 | DOI:10.1097/CM9.0000000000003081 (Source: Chinese Medical Journal)
Source: Chinese Medical Journal - March 4, 2024 Category: General Medicine Authors: Lin Yuan Zhiying Liu Xin Zhang Feili Wei Shan Guo Na Guo Lifeng Liu Zhenglai Ma Yunxia Ji Rui Wang Xiaofan Lu Zhen Li Wei Xia Hao Wu Tong Zhang Bin Su Source Type: research
Development of a droplet digital polymerase chain reaction assay for the sensitive detection of total and integrated HIV-1 DNA
CONCLUSIONS: This ddPCR assay can quantify total HIV DNA and integrated HIV DNA efficiently with robustness and sensitivity. It can be readily adapted for measuring HIV DNA with non-B clades, and it could be beneficial for testing in clinical trials.PMID:38433332 | DOI:10.1097/CM9.0000000000003081 (Source: Chinese Medical Journal)
Source: Chinese Medical Journal - March 4, 2024 Category: General Medicine Authors: Lin Yuan Zhiying Liu Xin Zhang Feili Wei Shan Guo Na Guo Lifeng Liu Zhenglai Ma Yunxia Ji Rui Wang Xiaofan Lu Zhen Li Wei Xia Hao Wu Tong Zhang Bin Su Source Type: research
Associations of demoimagedatas, aggravating factors, comorbidities, and treatments with atopic dermatitis severity in China: A national cross-sectional study
CONCLUSION: To enhance the management of AD, it is crucial to consider both aggravating factors and the increased utilization of systemic immunotherapy.REGISTRATION: ClinicalTrials.gov Identifier: NCT05316805, CORNERSTONE.PMID:38431766 | DOI:10.1097/CM9.0000000000003042 (Source: Chinese Medical Journal)
Source: Chinese Medical Journal - March 3, 2024 Category: General Medicine Authors: Jiahui Zhao Zhixin Zhang Hongguang Chen Xia Dou Zuotao Zhao Lingling Liu Yang Wang Hang Li Source Type: research
Incidence, prevalence, and causes of spinal injuries in China, 1990-2019: Findings from the Global Burden of Disease Study 2019
CONCLUSIONS: In China, the overall disease burden of spinal injuries increased significantly during the past three decades but varied considerably according to geoimagedataal location. The primary causes were falls and road injuries; however, the prevalence and specific causes differed across provinces.PMID:38431767 | DOI:10.1097/CM9.0000000000003045 (Source: Chinese Medical Journal)
Source: Chinese Medical Journal - March 3, 2024 Category: General Medicine Authors: Chenjun Liu Tingling Xu Weiwei Xia Shuai Xu Zhenqi Zhu Maigeng Zhou Haiying Liu Source Type: research
Granulomatosis with polyangiitis presented as multiple cutaneous abscesses after hysterectomy
Chin Med J (Engl). 2024 Mar 3. doi: 10.1097/CM9.0000000000002995. Online ahead of print.NO ABSTRACTPMID:38431768 | DOI:10.1097/CM9.0000000000002995 (Source: Chinese Medical Journal)
Source: Chinese Medical Journal - March 3, 2024 Category: General Medicine Authors: Xiaoting Song Mengrui Li Yinggai Song Ping Tu Hang Li Yang Wang Rong Xu Min Chen Xiaojuan Yu Suxia Wang Fude Zhou Minghui Zhao Ruoyu Li Xiaoyu Jia Xiaowen Wang Source Type: research
Clinical treatment procedure and experience of six gene-edited pig-rhesus monkey heterotopic heart xenotransplantation
Chin Med J (Engl). 2024 Feb 29. doi: 10.1097/CM9.0000000000003030. Online ahead of print.NO ABSTRACTPMID:38432900 | DOI:10.1097/CM9.0000000000003030 (Source: Chinese Medical Journal)
Source: Chinese Medical Journal - March 3, 2024 Category: General Medicine Authors: Bing Zhang Pengfei Ji Langang Peng Mengen Zhai Jiayou Tang Lin Zhao Yan Jin Baoling Xu Xiangni Lyu Linhe Lu Yenong Zhou Zhenxiao Jin Weixun Duan Xiuling Yang Wei Yi Jincheng Liu Source Type: research
Associations of demoimagedatas, aggravating factors, comorbidities, and treatments with atopic dermatitis severity in China: A national cross-sectional study
CONCLUSION: To enhance the management of AD, it is crucial to consider both aggravating factors and the increased utilization of systemic immunotherapy.REGISTRATION: ClinicalTrials.gov Identifier: NCT05316805, CORNERSTONE.PMID:38431766 | DOI:10.1097/CM9.0000000000003042 (Source: Chinese Medical Journal)
Source: Chinese Medical Journal - March 3, 2024 Category: General Medicine Authors: Jiahui Zhao Zhixin Zhang Hongguang Chen Xia Dou Zuotao Zhao Lingling Liu Yang Wang Hang Li Source Type: research
