Progress and perspective of organoid technology in breast cancer research
Chin Med J (Engl). 2024 Jan 8. doi: 10.1097/CM9.0000000000002889. Online ahead of print.ABSTRACTBreast cancer, a malignant tumor with a high incidence in women, lacks in vitro research models that can represent the biological functions of breast tumors in vivo. As a new biological tool, the organoid model has unique advantages over traditional methods, such as cell culture and patient-derived xenografts. Combining organoids with other emerging technologies, such as gene engineering and microfluidic chip technology, provides an effective method to compensate for the deficiencies in organoid models of breast cancer in vivo. ...
Source: Chinese Medical Journal - January 8, 2024 Category: General Medicine Authors: Changsheng Huang Hongyan Jin Source Type: research
Correlation between rate-pressure product or pressure-rate quotient and urinary albumin-creatinine ratio in the Chinese older population: The REACTION study
Chin Med J (Engl). 2024 Jan 8. doi: 10.1097/CM9.0000000000002941. Online ahead of print.NO ABSTRACTPMID:38185831 | DOI:10.1097/CM9.0000000000002941 (Source: Chinese Medical Journal)
Source: Chinese Medical Journal - January 8, 2024 Category: General Medicine Authors: Linghuan Wang Peixin Wu Kang Chen Binqi Li Jie Wang Yiming Mu Source Type: research
LONP1 ameliorates liver injury and improves gluconeogenesis dysfunction in acute-on-chronic liver failure
CONCLUSION: We demonstrated that gluconeogenesis dysfunction exists in ACLF, and LONP1 could ameliorate liver injury and improve gluconeogenic dysfunction, which would provide a promising therapeutic target for patients with ACLF.PMID:38184784 | DOI:10.1097/CM9.0000000000002969 (Source: Chinese Medical Journal)
Source: Chinese Medical Journal - January 7, 2024 Category: General Medicine Authors: Muchen Wu Jing Wu Kai Liu Minjie Jiang Fang Xie Xuehong Yin Jushan Wu Qinghua Meng Source Type: research
LONP1 ameliorates liver injury and improves gluconeogenesis dysfunction in acute-on-chronic liver failure
CONCLUSION: We demonstrated that gluconeogenesis dysfunction exists in ACLF, and LONP1 could ameliorate liver injury and improve gluconeogenic dysfunction, which would provide a promising therapeutic target for patients with ACLF.PMID:38184784 | DOI:10.1097/CM9.0000000000002969 (Source: Chinese Medical Journal)
Source: Chinese Medical Journal - January 7, 2024 Category: General Medicine Authors: Muchen Wu Jing Wu Kai Liu Minjie Jiang Fang Xie Xuehong Yin Jushan Wu Qinghua Meng Source Type: research
Circulating biomarker- and magnetic resonance-based nomogram predicting long-term outcomes in dilated cardiomyopathy
CONCLUSIONS: We established and validated a circulating biomarker- and CMRI-based nomogram that could provide a personalized prediction of ACM/HTx for DCM patients, which might help risk stratification and decision-making in clinical practice.PMID:38178323 | PMC:PMC10766284 | DOI:10.1097/CM9.0000000000002688 (Source: Chinese Medical Journal)
Source: Chinese Medical Journal - January 5, 2024 Category: General Medicine Authors: Yupeng Liu Wenyao Wang Jingjing Song Jiancheng Wang Yi Fu Yida Tang Source Type: research
Promotion effect of FOXCUT as a microRNA sponge for miR-24-3p on progression in triple-negative breast cancer through the p38 MAPK signaling pathway
CONCLUSION: Collectively, this research revealed a novel FOXCUT/miR-24-3p/p38 axis that affected breast cancer progression and suggested that the lncRNA FOXCUT could be a diagnostic marker and therapeutic target for breast cancer.PMID:38178324 | PMC:PMC10766298 | DOI:10.1097/CM9.0000000000002700 (Source: Chinese Medical Journal)
Source: Chinese Medical Journal - January 5, 2024 Category: General Medicine Authors: Xiafei Yu Fangze Qian Xiaoqiang Zhang Yanhui Zhu Gao He Junzhe Yang Xian Wu Yi Zhou Li Shen Xiaoyue Shi Hongfei Zhang Xiao'an Liu Source Type: research
Impact of peri-operative venous thromboembolism on survival in patients with endometrial clear cell carcinoma: A 10-year single-institution retrospective study
Chin Med J (Engl). 2024 Jan 5. doi: 10.1097/CM9.0000000000002951. Online ahead of print.NO ABSTRACTPMID:38180807 | DOI:10.1097/CM9.0000000000002951 (Source: Chinese Medical Journal)
Source: Chinese Medical Journal - January 5, 2024 Category: General Medicine Authors: Xuesong Ding Yuan Li Dongyan Cao Xirun Wan Ming Wu Lingya Pan Junjun Yang Yang Xiang Source Type: research
Circulating biomarker- and magnetic resonance-based nomogram predicting long-term outcomes in dilated cardiomyopathy
CONCLUSIONS: We established and validated a circulating biomarker- and CMRI-based nomogram that could provide a personalized prediction of ACM/HTx for DCM patients, which might help risk stratification and decision-making in clinical practice.PMID:38178323 | DOI:10.1097/CM9.0000000000002688 (Source: Chinese Medical Journal)
Source: Chinese Medical Journal - January 5, 2024 Category: General Medicine Authors: Yupeng Liu Wenyao Wang Jingjing Song Jiancheng Wang Yi Fu Yida Tang Source Type: research
Promotion effect of FOXCUT as a microRNA sponge for miR-24-3p on progression in triple-negative breast cancer through the p38 MAPK signaling pathway
CONCLUSION: Collectively, this research revealed a novel FOXCUT/miR-24-3p/p38 axis that affected breast cancer progression and suggested that the lncRNA FOXCUT could be a diagnostic marker and therapeutic target for breast cancer.PMID:38178324 | DOI:10.1097/CM9.0000000000002700 (Source: Chinese Medical Journal)
Source: Chinese Medical Journal - January 5, 2024 Category: General Medicine Authors: Xiafei Yu Fangze Qian Xiaoqiang Zhang Yanhui Zhu Gao He Junzhe Yang Xian Wu Yi Zhou Li Shen Xiaoyue Shi Hongfei Zhang Xiao'an Liu Source Type: research
Impact of peri-operative venous thromboembolism on survival in patients with endometrial clear cell carcinoma: A 10-year single-institution retrospective study
Chin Med J (Engl). 2024 Jan 5. doi: 10.1097/CM9.0000000000002951. Online ahead of print.NO ABSTRACTPMID:38180807 | DOI:10.1097/CM9.0000000000002951 (Source: Chinese Medical Journal)
Source: Chinese Medical Journal - January 5, 2024 Category: General Medicine Authors: Xuesong Ding Yuan Li Dongyan Cao Xirun Wan Ming Wu Lingya Pan Junjun Yang Yang Xiang Source Type: research
Circulating biomarker- and magnetic resonance-based nomogram predicting long-term outcomes in dilated cardiomyopathy
CONCLUSIONS: We established and validated a circulating biomarker- and CMRI-based nomogram that could provide a personalized prediction of ACM/HTx for DCM patients, which might help risk stratification and decision-making in clinical practice.PMID:38178323 | DOI:10.1097/CM9.0000000000002688 (Source: Chinese Medical Journal)
Source: Chinese Medical Journal - January 5, 2024 Category: General Medicine Authors: Yupeng Liu Wenyao Wang Jingjing Song Jiancheng Wang Yi Fu Yida Tang Source Type: research
Promotion effect of FOXCUT as a microRNA sponge for miR-24-3p on progression in triple-negative breast cancer through the p38 MAPK signaling pathway
CONCLUSION: Collectively, this research revealed a novel FOXCUT/miR-24-3p/p38 axis that affected breast cancer progression and suggested that the lncRNA FOXCUT could be a diagnostic marker and therapeutic target for breast cancer.PMID:38178324 | DOI:10.1097/CM9.0000000000002700 (Source: Chinese Medical Journal)
Source: Chinese Medical Journal - January 5, 2024 Category: General Medicine Authors: Xiafei Yu Fangze Qian Xiaoqiang Zhang Yanhui Zhu Gao He Junzhe Yang Xian Wu Yi Zhou Li Shen Xiaoyue Shi Hongfei Zhang Xiao'an Liu Source Type: research
Instructions for Authors
Chin Med J (Engl). 2024 Jan 5;137(1):123-126. doi: 10.1097/01.CM9.0001005820.83545.61. Epub 2024 Jan 5.NO ABSTRACTPMID:38178325 | DOI:10.1097/01.CM9.0001005820.83545.61 (Source: Chinese Medical Journal)
Source: Chinese Medical Journal - January 5, 2024 Category: General Medicine Source Type: research
AZD1775 and anti-PD-1 antibody synergistically sensitize hepatoma to radiotherapy
CONCLUSIONS: This work suggests that AZD1775 and anti-PD-1 Ab synergistically sensitize hepatoma to radiotherapy by enhancing IR-induced DNA damage and improving cytotoxic CD8+ T cells in TME.PMID:38167245 | DOI:10.1097/CM9.0000000000002988 (Source: Chinese Medical Journal)
Source: Chinese Medical Journal - January 3, 2024 Category: General Medicine Authors: Yichun Yin Jian Wang Junxuan Yi Kaiyue Zhang Zimeng Yin Sunzi Jin Baisong Zheng Source Type: research
Clinical application and management of temporary mechanical circulatory support: A clinical consensus
Chin Med J (Engl). 2023 Dec 26. doi: 10.1097/CM9.0000000000002980. Online ahead of print.NO ABSTRACTPMID:38155554 | DOI:10.1097/CM9.0000000000002980 (Source: Chinese Medical Journal)
Source: Chinese Medical Journal - December 29, 2023 Category: General Medicine Authors: Nianguo Dong Liangwan Chen Xin Chen Huishan Wang Yingbin Xiao Xianqiang Wang Jinsong Huang Yang Yan Pramod Bonde Neel Sodha Pavan Atluri Juan Pablo Maureira Andr é Vincentelli Masanobu Yanase Yixuan Wang Haitao Zhang Xiaotong Hou Yoshijuki Takami Pascal Source Type: research
