Umami taste perception and preferences of the domestic cat (Felis catus), an obligate carnivore
Chem Senses. 2023 Aug 8:bjad026. doi: 10.1093/chemse/bjad026. Online ahead of print.ABSTRACTThe domestic cat (Felis catus) is an obligate carnivore, and as such has a meat-based diet. Several studies on the taste perception of cats have been reported, indicating that their sense of taste has evolved based on their carnivorous diet. Here we propose that umami (mediated by Tas1r1-Tas1r3) is the main appetitive taste modality for the domestic cat by characterising the umami taste of a range of nucleotides, amino acids and their mixtures for cats obtained using complementary methods. We show for the first time that cats expres...
Source: Chemical Senses - August 8, 2023 Category: Biochemistry Authors: Scott J McGrane Matthew Gibbs Carlos Hernangomez de Alvaro Nicola Dunlop Marcel Winnig Boris Klebansky Daniel Waller Source Type: research
Umami taste perception and preferences of the domestic cat (Felis catus), an obligate carnivore
Chem Senses. 2023 Aug 8:bjad026. doi: 10.1093/chemse/bjad026. Online ahead of print.ABSTRACTThe domestic cat (Felis catus) is an obligate carnivore, and as such has a meat-based diet. Several studies on the taste perception of cats have been reported, indicating that their sense of taste has evolved based on their carnivorous diet. Here we propose that umami (mediated by Tas1r1-Tas1r3) is the main appetitive taste modality for the domestic cat by characterising the umami taste of a range of nucleotides, amino acids and their mixtures for cats obtained using complementary methods. We show for the first time that cats expres...
Source: Chemical Senses - August 8, 2023 Category: Biochemistry Authors: Scott J McGrane Matthew Gibbs Carlos Hernangomez de Alvaro Nicola Dunlop Marcel Winnig Boris Klebansky Daniel Waller Source Type: research
Umami taste perception and preferences of the domestic cat (Felis catus), an obligate carnivore
Chem Senses. 2023 Aug 8:bjad026. doi: 10.1093/chemse/bjad026. Online ahead of print.ABSTRACTThe domestic cat (Felis catus) is an obligate carnivore, and as such has a meat-based diet. Several studies on the taste perception of cats have been reported, indicating that their sense of taste has evolved based on their carnivorous diet. Here we propose that umami (mediated by Tas1r1-Tas1r3) is the main appetitive taste modality for the domestic cat by characterising the umami taste of a range of nucleotides, amino acids and their mixtures for cats obtained using complementary methods. We show for the first time that cats expres...
Source: Chemical Senses - August 8, 2023 Category: Biochemistry Authors: Scott J McGrane Matthew Gibbs Carlos Hernangomez de Alvaro Nicola Dunlop Marcel Winnig Boris Klebansky Daniel Waller Source Type: research
Gene expression analyses of TAS1R taste receptors relevant to the treatment of cardiometabolic disease
This study aimed to delineate expression of the STR in extraoral tissues using publicly available RNA-sequencing repositories. Gene expression data was mined for all genes implicated in the structure and function of the STR, and control genes including highly expressed metabolic genes in relevant tissues, other GPCRs and effector G proteins with physiological roles in metabolism, and other GPCRs with expression exclusively outside the metabolic tissues. Since the physiological role of the STR in extraoral tissues is likely related to glucose sensing, expression was then examined in diseases related to glucose-sensing impai...
Source: Chemical Senses - August 4, 2023 Category: Biochemistry Authors: Mariah R Stavrou Sean Souchiart So Angela M Finch Sara Ballouz Nicola J Smith Source Type: research
Gene expression analyses of TAS1R taste receptors relevant to the treatment of cardiometabolic disease
This study aimed to delineate expression of the STR in extraoral tissues using publicly available RNA-sequencing repositories. Gene expression data was mined for all genes implicated in the structure and function of the STR, and control genes including highly expressed metabolic genes in relevant tissues, other GPCRs and effector G proteins with physiological roles in metabolism, and other GPCRs with expression exclusively outside the metabolic tissues. Since the physiological role of the STR in extraoral tissues is likely related to glucose sensing, expression was then examined in diseases related to glucose-sensing impai...
Source: Chemical Senses - August 4, 2023 Category: Biochemistry Authors: Mariah R Stavrou Sean Souchiart So Angela M Finch Sara Ballouz Nicola J Smith Source Type: research
Gene expression analyses of TAS1R taste receptors relevant to the treatment of cardiometabolic disease
This study aimed to delineate expression of the STR in extraoral tissues using publicly available RNA-sequencing repositories. Gene expression data was mined for all genes implicated in the structure and function of the STR, and control genes including highly expressed metabolic genes in relevant tissues, other GPCRs and effector G proteins with physiological roles in metabolism, and other GPCRs with expression exclusively outside the metabolic tissues. Since the physiological role of the STR in extraoral tissues is likely related to glucose sensing, expression was then examined in diseases related to glucose-sensing impai...
Source: Chemical Senses - August 4, 2023 Category: Biochemistry Authors: Mariah R Stavrou Sean Souchiart So Angela M Finch Sara Ballouz Nicola J Smith Source Type: research
Gene expression analyses of TAS1R taste receptors relevant to the treatment of cardiometabolic disease
This study aimed to delineate expression of the STR in extraoral tissues using publicly available RNA-sequencing repositories. Gene expression data was mined for all genes implicated in the structure and function of the STR, and control genes including highly expressed metabolic genes in relevant tissues, other GPCRs and effector G proteins with physiological roles in metabolism, and other GPCRs with expression exclusively outside the metabolic tissues. Since the physiological role of the STR in extraoral tissues is likely related to glucose sensing, expression was then examined in diseases related to glucose-sensing impai...
Source: Chemical Senses - August 4, 2023 Category: Biochemistry Authors: Mariah R Stavrou Sean Souchiart So Angela M Finch Sara Ballouz Nicola J Smith Source Type: research
Effects of zinc deficiency on the regeneration of olfactory epithelium in mice
Chem Senses. 2023 Aug 1:bjad023. doi: 10.1093/chemse/bjad023. Online ahead of print.ABSTRACTThe olfactory epithelium can regenerate after damage; however, the regeneration process is affected by various factors, such as viral infections, head trauma, and medications. Zinc is an essential trace element that has important roles in organ development, growth, and maturation. Zinc also helps regulate neurotransmission in the brain; nevertheless, its relationship with olfactory epithelium regeneration remains unclear. Therefore, we used a severe zinc deficiency mouse model to investigate the effects of zinc deficiency on olfacto...
Source: Chemical Senses - August 1, 2023 Category: Biochemistry Authors: Hiroyuki Ikushima Jun Suzuki Tomotaka Hemmi Ryoukichi Ikeda Yuta Kobayashi Nobuo Ohta Yukio Katori Source Type: research
Effects of zinc deficiency on the regeneration of olfactory epithelium in mice
Chem Senses. 2023 Aug 1:bjad023. doi: 10.1093/chemse/bjad023. Online ahead of print.ABSTRACTThe olfactory epithelium can regenerate after damage; however, the regeneration process is affected by various factors, such as viral infections, head trauma, and medications. Zinc is an essential trace element that has important roles in organ development, growth, and maturation. Zinc also helps regulate neurotransmission in the brain; nevertheless, its relationship with olfactory epithelium regeneration remains unclear. Therefore, we used a severe zinc deficiency mouse model to investigate the effects of zinc deficiency on olfacto...
Source: Chemical Senses - August 1, 2023 Category: Biochemistry Authors: Hiroyuki Ikushima Jun Suzuki Tomotaka Hemmi Ryoukichi Ikeda Yuta Kobayashi Nobuo Ohta Yukio Katori Source Type: research
Effects of zinc deficiency on the regeneration of olfactory epithelium in mice
Chem Senses. 2023 Aug 1:bjad023. doi: 10.1093/chemse/bjad023. Online ahead of print.ABSTRACTThe olfactory epithelium can regenerate after damage; however, the regeneration process is affected by various factors, such as viral infections, head trauma, and medications. Zinc is an essential trace element that has important roles in organ development, growth, and maturation. Zinc also helps regulate neurotransmission in the brain; nevertheless, its relationship with olfactory epithelium regeneration remains unclear. Therefore, we used a severe zinc deficiency mouse model to investigate the effects of zinc deficiency on olfacto...
Source: Chemical Senses - August 1, 2023 Category: Biochemistry Authors: Hiroyuki Ikushima Jun Suzuki Tomotaka Hemmi Ryoukichi Ikeda Yuta Kobayashi Nobuo Ohta Yukio Katori Source Type: research
Reply: taste loss as a distinct symptom of COVID-19: a systematic review and meta-analysis
Chem Senses. 2023 Jan 1;48:bjad012. doi: 10.1093/chemse/bjad012.NO ABSTRACTPMID:37503715 | DOI:10.1093/chemse/bjad012 (Source: Chemical Senses)
Source: Chemical Senses - July 28, 2023 Category: Biochemistry Authors: Mackenzie E Hannum Riley J Koch Vicente A Ramirez Sarah S Marks Aurora K Toskala Riley D Herriman Cailu Lin Paule V Joseph Danielle R Reed Source Type: research
Expression of concern: Taste loss as a distinct symptom of COVID-19: a systematic review and meta-analysis
Chem Senses. 2023 Jan 1;48:bjad019. doi: 10.1093/chemse/bjad019.NO ABSTRACTPMID:37503716 | DOI:10.1093/chemse/bjad019 (Source: Chemical Senses)
Source: Chemical Senses - July 28, 2023 Category: Biochemistry Source Type: research
The psychophysical assessment of gustatory dysfunction in COVID-19
Chem Senses. 2023 Jan 1;48:bjad011. doi: 10.1093/chemse/bjad011.NO ABSTRACTPMID:37503717 | DOI:10.1093/chemse/bjad011 (Source: Chemical Senses)
Source: Chemical Senses - July 28, 2023 Category: Biochemistry Authors: Constantin A Hintschich David T Liu Thomas Hummel Source Type: research
Reply: taste loss as a distinct symptom of COVID-19: a systematic review and meta-analysis
Chem Senses. 2023 Jan 1;48:bjad012. doi: 10.1093/chemse/bjad012.NO ABSTRACTPMID:37503715 | DOI:10.1093/chemse/bjad012 (Source: Chemical Senses)
Source: Chemical Senses - July 28, 2023 Category: Biochemistry Authors: Mackenzie E Hannum Riley J Koch Vicente A Ramirez Sarah S Marks Aurora K Toskala Riley D Herriman Cailu Lin Paule V Joseph Danielle R Reed Source Type: research
Expression of concern: Taste loss as a distinct symptom of COVID-19: a systematic review and meta-analysis
Chem Senses. 2023 Jan 1;48:bjad019. doi: 10.1093/chemse/bjad019.NO ABSTRACTPMID:37503716 | DOI:10.1093/chemse/bjad019 (Source: Chemical Senses)
Source: Chemical Senses - July 28, 2023 Category: Biochemistry Source Type: research
