Oral thermal processing in the gustatory cortex of awake mice
Chem Senses. 2023 Oct 18:bjad042. doi: 10.1093/chemse/bjad042. Online ahead of print.ABSTRACTOral temperature is a sensory cue relevant to food preference and nutrition. To understand how orally-sourced thermal inputs are represented in the gustatory cortex (GC), we recorded neural responses from the GC of male and female mice presented with deionized water at different innocuous temperatures (14 °C, 25 °C, 36 °C) and taste stimuli (room temperature). Our results demonstrate that GC neurons encode orally-sourced thermal information in the absence of classical taste qualities at the single neuron and population levels, a...
Source: Chemical Senses - October 18, 2023 Category: Biochemistry Authors: Cecilia G Bouaichi Katherine E Odegaard Camden Neese Roberto Vincis Source Type: research
Oral thermal processing in the gustatory cortex of awake mice
Chem Senses. 2023 Oct 18:bjad042. doi: 10.1093/chemse/bjad042. Online ahead of print.ABSTRACTOral temperature is a sensory cue relevant to food preference and nutrition. To understand how orally-sourced thermal inputs are represented in the gustatory cortex (GC), we recorded neural responses from the GC of male and female mice presented with deionized water at different innocuous temperatures (14 °C, 25 °C, 36 °C) and taste stimuli (room temperature). Our results demonstrate that GC neurons encode orally-sourced thermal information in the absence of classical taste qualities at the single neuron and population levels, a...
Source: Chemical Senses - October 18, 2023 Category: Biochemistry Authors: Cecilia G Bouaichi Katherine E Odegaard Camden Neese Roberto Vincis Source Type: research
Expression of taste sentinels, T1R, T2R, and PLC ß2, on the passageway for olfactory signals in zebrafish
Chem Senses. 2023 Oct 16:bjad040. doi: 10.1093/chemse/bjad040. Online ahead of print.ABSTRACTThe senses of taste and smell detect overlapping sets of chemical compounds in fish, e.g. amino acids are detected by both senses. However, so far taste and smell organs appeared morphologically to be very distinct, with a specialized olfactory epithelium for detection of odors and taste buds located in the oral cavity and lip for detection of tastants. Here we report dense clusters of cells expressing T1R and T2R receptors as well as their signal transduction molecule PLCß2 in nostrils of zebrafish, i.e. on the entrance funnel th...
Source: Chemical Senses - October 16, 2023 Category: Biochemistry Authors: G ünes Birdal Percival P D'Gama Nathalie Jurisch-Yaksi Sigrun I Korsching Source Type: research
Expression of taste sentinels, T1R, T2R, and PLC ß2, on the passageway for olfactory signals in zebrafish
Chem Senses. 2023 Oct 16:bjad040. doi: 10.1093/chemse/bjad040. Online ahead of print.ABSTRACTThe senses of taste and smell detect overlapping sets of chemical compounds in fish, e.g. amino acids are detected by both senses. However, so far taste and smell organs appeared morphologically to be very distinct, with a specialized olfactory epithelium for detection of odors and taste buds located in the oral cavity and lip for detection of tastants. Here we report dense clusters of cells expressing T1R and T2R receptors as well as their signal transduction molecule PLCß2 in nostrils of zebrafish, i.e. on the entrance funnel th...
Source: Chemical Senses - October 16, 2023 Category: Biochemistry Authors: G ünes Birdal Percival P D'Gama Nathalie Jurisch-Yaksi Sigrun I Korsching Source Type: research
Expression of taste sentinels, T1R, T2R, and PLC ß2, on the passageway for olfactory signals in zebrafish
Chem Senses. 2023 Oct 16:bjad040. doi: 10.1093/chemse/bjad040. Online ahead of print.ABSTRACTThe senses of taste and smell detect overlapping sets of chemical compounds in fish, e.g. amino acids are detected by both senses. However, so far taste and smell organs appeared morphologically to be very distinct, with a specialized olfactory epithelium for detection of odors and taste buds located in the oral cavity and lip for detection of tastants. Here we report dense clusters of cells expressing T1R and T2R receptors as well as their signal transduction molecule PLCß2 in nostrils of zebrafish, i.e. on the entrance funnel th...
Source: Chemical Senses - October 16, 2023 Category: Biochemistry Authors: G ünes Birdal Percival P D'Gama Nathalie Jurisch-Yaksi Sigrun I Korsching Source Type: research
Appetite-regulating hormones modulate odor perception and odor-evoked activity in hypothalamus and olfactory cortices
Chem Senses. 2023 Oct 5:bjad039. doi: 10.1093/chemse/bjad039. Online ahead of print.ABSTRACTOdors guide food seeking, and food intake modulates olfactory function. This interaction is mediated by appetite-regulating hormones like ghrelin, insulin, and leptin, which alter activity in the rodent olfactory bulb, but their effects on downstream olfactory cortices have not yet been established in humans. The olfactory tract connects the olfactory bulb to the cortex through three main striae, terminating in the piriform cortex (PirC), amygdala (AMY), olfactory tubercule (OT), and anterior olfactory nucleus (AON). Here, we test t...
Source: Chemical Senses - October 5, 2023 Category: Biochemistry Authors: Yao Zhao Surabhi Bhutani Thorsten Kahnt Source Type: research
Appetite-regulating hormones modulate odor perception and odor-evoked activity in hypothalamus and olfactory cortices
Chem Senses. 2023 Oct 5:bjad039. doi: 10.1093/chemse/bjad039. Online ahead of print.ABSTRACTOdors guide food seeking, and food intake modulates olfactory function. This interaction is mediated by appetite-regulating hormones like ghrelin, insulin, and leptin, which alter activity in the rodent olfactory bulb, but their effects on downstream olfactory cortices have not yet been established in humans. The olfactory tract connects the olfactory bulb to the cortex through three main striae, terminating in the piriform cortex (PirC), amygdala (AMY), olfactory tubercule (OT), and anterior olfactory nucleus (AON). Here, we test t...
Source: Chemical Senses - October 5, 2023 Category: Biochemistry Authors: Yao Zhao Surabhi Bhutani Thorsten Kahnt Source Type: research
Appetite-regulating hormones modulate odor perception and odor-evoked activity in hypothalamus and olfactory cortices
Chem Senses. 2023 Oct 5:bjad039. doi: 10.1093/chemse/bjad039. Online ahead of print.ABSTRACTOdors guide food seeking, and food intake modulates olfactory function. This interaction is mediated by appetite-regulating hormones like ghrelin, insulin, and leptin, which alter activity in the rodent olfactory bulb, but their effects on downstream olfactory cortices have not yet been established in humans. The olfactory tract connects the olfactory bulb to the cortex through three main striae, terminating in the piriform cortex (PirC), amygdala (AMY), olfactory tubercule (OT), and anterior olfactory nucleus (AON). Here, we test t...
Source: Chemical Senses - October 5, 2023 Category: Biochemistry Authors: Yao Zhao Surabhi Bhutani Thorsten Kahnt Source Type: research
Appetite-regulating hormones modulate odor perception and odor-evoked activity in hypothalamus and olfactory cortices
Chem Senses. 2023 Oct 5:bjad039. doi: 10.1093/chemse/bjad039. Online ahead of print.ABSTRACTOdors guide food seeking, and food intake modulates olfactory function. This interaction is mediated by appetite-regulating hormones like ghrelin, insulin, and leptin, which alter activity in the rodent olfactory bulb, but their effects on downstream olfactory cortices have not yet been established in humans. The olfactory tract connects the olfactory bulb to the cortex through three main striae, terminating in the piriform cortex (PirC), amygdala (AMY), olfactory tubercule (OT), and anterior olfactory nucleus (AON). Here, we test t...
Source: Chemical Senses - October 5, 2023 Category: Biochemistry Authors: Yao Zhao Surabhi Bhutani Thorsten Kahnt Source Type: research
Appetite-regulating hormones modulate odor perception and odor-evoked activity in hypothalamus and olfactory cortices
Chem Senses. 2023 Oct 5:bjad039. doi: 10.1093/chemse/bjad039. Online ahead of print.ABSTRACTOdors guide food seeking, and food intake modulates olfactory function. This interaction is mediated by appetite-regulating hormones like ghrelin, insulin, and leptin, which alter activity in the rodent olfactory bulb, but their effects on downstream olfactory cortices have not yet been established in humans. The olfactory tract connects the olfactory bulb to the cortex through three main striae, terminating in the piriform cortex (PirC), amygdala (AMY), olfactory tubercule (OT), and anterior olfactory nucleus (AON). Here, we test t...
Source: Chemical Senses - October 5, 2023 Category: Biochemistry Authors: Yao Zhao Surabhi Bhutani Thorsten Kahnt Source Type: research
Appetite-regulating hormones modulate odor perception and odor-evoked activity in hypothalamus and olfactory cortices
Chem Senses. 2023 Oct 5:bjad039. doi: 10.1093/chemse/bjad039. Online ahead of print.ABSTRACTOdors guide food seeking, and food intake modulates olfactory function. This interaction is mediated by appetite-regulating hormones like ghrelin, insulin, and leptin, which alter activity in the rodent olfactory bulb, but their effects on downstream olfactory cortices have not yet been established in humans. The olfactory tract connects the olfactory bulb to the cortex through three main striae, terminating in the piriform cortex (PirC), amygdala (AMY), olfactory tubercule (OT), and anterior olfactory nucleus (AON). Here, we test t...
Source: Chemical Senses - October 5, 2023 Category: Biochemistry Authors: Yao Zhao Surabhi Bhutani Thorsten Kahnt Source Type: research
Appetite-regulating hormones modulate odor perception and odor-evoked activity in hypothalamus and olfactory cortices
Chem Senses. 2023 Oct 5:bjad039. doi: 10.1093/chemse/bjad039. Online ahead of print.ABSTRACTOdors guide food seeking, and food intake modulates olfactory function. This interaction is mediated by appetite-regulating hormones like ghrelin, insulin, and leptin, which alter activity in the rodent olfactory bulb, but their effects on downstream olfactory cortices have not yet been established in humans. The olfactory tract connects the olfactory bulb to the cortex through three main striae, terminating in the piriform cortex (PirC), amygdala (AMY), olfactory tubercule (OT), and anterior olfactory nucleus (AON). Here, we test t...
Source: Chemical Senses - October 5, 2023 Category: Biochemistry Authors: Yao Zhao Surabhi Bhutani Thorsten Kahnt Source Type: research
Appetite-regulating hormones modulate odor perception and odor-evoked activity in hypothalamus and olfactory cortices
Chem Senses. 2023 Oct 5:bjad039. doi: 10.1093/chemse/bjad039. Online ahead of print.ABSTRACTOdors guide food seeking, and food intake modulates olfactory function. This interaction is mediated by appetite-regulating hormones like ghrelin, insulin, and leptin, which alter activity in the rodent olfactory bulb, but their effects on downstream olfactory cortices have not yet been established in humans. The olfactory tract connects the olfactory bulb to the cortex through three main striae, terminating in the piriform cortex (PirC), amygdala (AMY), olfactory tubercule (OT), and anterior olfactory nucleus (AON). Here, we test t...
Source: Chemical Senses - October 5, 2023 Category: Biochemistry Authors: Yao Zhao Surabhi Bhutani Thorsten Kahnt Source Type: research
Liking of salt is associated with depression, anxiety, and stress
Chem Senses. 2023 Sep 20:bjad038. doi: 10.1093/chemse/bjad038. Online ahead of print.ABSTRACTEarly research has shown variations in salt taste qualities in depression, anxiety, and stress. These studies evaluated changes to salt taste intensity and liking (pleasantness) of salt solutions but not of salty foods. Therefore, an Australian population survey (n = 424) was conducted where participants rated recalled intensity and liking of salt index foods and completed the Depression, Anxiety, and Stress Scale (DASS-21) to measure these states. Standard least squares regression (post hoc Tukey's HSD) compared means between grou...
Source: Chemical Senses - September 22, 2023 Category: Biochemistry Authors: Celeste Ferraris Christopher J Scarlett Tamara Bucher Emma L Beckett Source Type: research
Liking of salt is associated with depression, anxiety, and stress
Chem Senses. 2023 Sep 20:bjad038. doi: 10.1093/chemse/bjad038. Online ahead of print.ABSTRACTEarly research has shown variations in salt taste qualities in depression, anxiety, and stress. These studies evaluated changes to salt taste intensity and liking (pleasantness) of salt solutions but not of salty foods. Therefore, an Australian population survey (n = 424) was conducted where participants rated recalled intensity and liking of salt index foods and completed the Depression, Anxiety, and Stress Scale (DASS-21) to measure these states. Standard least squares regression (post hoc Tukey's HSD) compared means between grou...
Source: Chemical Senses - September 22, 2023 Category: Biochemistry Authors: Celeste Ferraris Christopher J Scarlett Tamara Bucher Emma L Beckett Source Type: research
