Cyclophosphamide induces the loss of taste bud innervation in mice
Chem Senses. 2024 Feb 29:bjae010. doi: 10.1093/chemse/bjae010. Online ahead of print.ABSTRACTMany common chemotherapeutics produce disruptions in the sense of taste which can lead to loss of appetite, nutritional imbalance, and reduced quality of life, especially if taste loss persists after treatment ends. Cyclophosphamide (CYP), an alkylating chemotherapeutic agent, affects taste sensitivity through its cytotoxic effects on mature taste receptor cells (TRCs) and on taste progenitor cell populations, retarding the capacity to replace TRCs. Mechanistic studies have focused primarily on taste cells, however, taste signaling...
Source: Chemical Senses - February 29, 2024 Category: Biochemistry Authors: Ryan M Wood Erin L Vasquez Krystal A Goyins Eduardo Gutierrez Kuri Kevin Connelly Saima Humayun Lindsey J Macpherson Source Type: research
What are Olfaction and Gustation, And Do All Animals Have Them?
Chem Senses. 2024 Feb 29:bjae009. doi: 10.1093/chemse/bjae009. Online ahead of print.ABSTRACTDifferent animals have distinctive anatomical and physiological properties to their chemical senses that enhance detection and discrimination of relevant chemical cues. Humans and other vertebrates are recognized as having two main chemical senses, olfaction and gustation, distinguished from each other by their evolutionarily conserved neuroanatomical organization. This distinction between olfaction and gustation in vertebrates is not based on the medium in which they live because the most ancestral and numerous vertebrates, the fi...
Source: Chemical Senses - February 29, 2024 Category: Biochemistry Authors: Charles D Derby John Caprio Source Type: research
Odor dilution sorting as a clinical test of olfactory function: normative values and reliability data
In conclusion, the olfactory sorting test represents a simple, self-administered approach to the detection of anosmia or preserved olfactory function. With balanced accuracy similar to existing brief olfactory tests, this method offers a practical and user-friendly alternative for screening anosmia, addressing the need for resource-efficient assessments in clinical settings.PMID:38401152 | DOI:10.1093/chemse/bjae008 (Source: Chemical Senses)
Source: Chemical Senses - February 24, 2024 Category: Biochemistry Authors: J örn Lötsch Anne Wolter Antje H ähner Thomas Hummel Source Type: research
Odor dilution sorting as a clinical test of olfactory function: normative values and reliability data
In conclusion, the olfactory sorting test represents a simple, self-administered approach to the detection of anosmia or preserved olfactory function. With balanced accuracy similar to existing brief olfactory tests, this method offers a practical and user-friendly alternative for screening anosmia, addressing the need for resource-efficient assessments in clinical settings.PMID:38401152 | DOI:10.1093/chemse/bjae008 (Source: Chemical Senses)
Source: Chemical Senses - February 24, 2024 Category: Biochemistry Authors: J örn Lötsch Anne Wolter Antje H ähner Thomas Hummel Source Type: research
Odor dilution sorting as a clinical test of olfactory function: normative values and reliability data
In conclusion, the olfactory sorting test represents a simple, self-administered approach to the detection of anosmia or preserved olfactory function. With balanced accuracy similar to existing brief olfactory tests, this method offers a practical and user-friendly alternative for screening anosmia, addressing the need for resource-efficient assessments in clinical settings.PMID:38401152 | DOI:10.1093/chemse/bjae008 (Source: Chemical Senses)
Source: Chemical Senses - February 24, 2024 Category: Biochemistry Authors: J örn Lötsch Anne Wolter Antje H ähner Thomas Hummel Source Type: research
Odor dilution sorting as a clinical test of olfactory function: normative values and reliability data
In conclusion, the olfactory sorting test represents a simple, self-administered approach to the detection of anosmia or preserved olfactory function. With balanced accuracy similar to existing brief olfactory tests, this method offers a practical and user-friendly alternative for screening anosmia, addressing the need for resource-efficient assessments in clinical settings.PMID:38401152 | DOI:10.1093/chemse/bjae008 (Source: Chemical Senses)
Source: Chemical Senses - February 24, 2024 Category: Biochemistry Authors: J örn Lötsch Anne Wolter Antje H ähner Thomas Hummel Source Type: research
Odor dilution sorting as a clinical test of olfactory function: normative values and reliability data
In conclusion, the olfactory sorting test represents a simple, self-administered approach to the detection of anosmia or preserved olfactory function. With balanced accuracy similar to existing brief olfactory tests, this method offers a practical and user-friendly alternative for screening anosmia, addressing the need for resource-efficient assessments in clinical settings.PMID:38401152 | DOI:10.1093/chemse/bjae008 (Source: Chemical Senses)
Source: Chemical Senses - February 24, 2024 Category: Biochemistry Authors: J örn Lötsch Anne Wolter Antje H ähner Thomas Hummel Source Type: research
Development of the gas chromatography/mass spectrometry-based aroma designer capable of modifying volatile chemical compositions in complex odors
In conclusion, the system developed here can improve aroma research by identifying key odorants from natural products.PMID:38386845 | DOI:10.1093/chemse/bjae007 (Source: Chemical Senses)
Source: Chemical Senses - February 22, 2024 Category: Biochemistry Authors: Kaname Obara Reiko Uenoyama Yutaro Obata Masao Miyazaki Source Type: research
Development of the gas chromatography/mass spectrometry-based aroma designer capable of modifying volatile chemical compositions in complex odors
In conclusion, the system developed here can improve aroma research by identifying key odorants from natural products.PMID:38386845 | DOI:10.1093/chemse/bjae007 (Source: Chemical Senses)
Source: Chemical Senses - February 22, 2024 Category: Biochemistry Authors: Kaname Obara Reiko Uenoyama Yutaro Obata Masao Miyazaki Source Type: research
A non-singularity in sweet taste
Chem Senses. 2024 Feb 15:bjae006. doi: 10.1093/chemse/bjae006. Online ahead of print.NO ABSTRACTPMID:38366583 | DOI:10.1093/chemse/bjae006 (Source: Chemical Senses)
Source: Chemical Senses - February 17, 2024 Category: Biochemistry Authors: Christian H Lemon Source Type: research
A non-singularity in sweet taste
Chem Senses. 2024 Feb 15:bjae006. doi: 10.1093/chemse/bjae006. Online ahead of print.NO ABSTRACTPMID:38366583 | DOI:10.1093/chemse/bjae006 (Source: Chemical Senses)
Source: Chemical Senses - February 17, 2024 Category: Biochemistry Authors: Christian H Lemon Source Type: research
A non-singularity in sweet taste
Chem Senses. 2024 Feb 15:bjae006. doi: 10.1093/chemse/bjae006. Online ahead of print.NO ABSTRACTPMID:38366583 | DOI:10.1093/chemse/bjae006 (Source: Chemical Senses)
Source: Chemical Senses - February 17, 2024 Category: Biochemistry Authors: Christian H Lemon Source Type: research
A non-singularity in sweet taste
Chem Senses. 2024 Feb 15:bjae006. doi: 10.1093/chemse/bjae006. Online ahead of print.NO ABSTRACTPMID:38366583 | DOI:10.1093/chemse/bjae006 (Source: Chemical Senses)
Source: Chemical Senses - February 17, 2024 Category: Biochemistry Authors: Christian H Lemon Source Type: research
A non-singularity in sweet taste
Chem Senses. 2024 Feb 15:bjae006. doi: 10.1093/chemse/bjae006. Online ahead of print.NO ABSTRACTPMID:38366583 | DOI:10.1093/chemse/bjae006 (Source: Chemical Senses)
Source: Chemical Senses - February 17, 2024 Category: Biochemistry Authors: Christian H Lemon Source Type: research
Methodologies for smellwalks and scentwalks- a critical review
Chem Senses. 2024 Feb 13:bjae005. doi: 10.1093/chemse/bjae005. Online ahead of print.ABSTRACTOlfactory elements of the human environment are essential with respect to culture, society and heritage, and robust methodological approaches are necessary to identify and describe aspects of this sensory component. To accurately investigate and advance knowledge of olfactory composition of spaces and places, that is, a smellscape - an olfactory contextualized landscape - innovative methodologies such as smellwalks can be employed as part of the research approach. Despite the increasing use of smellwalks, there is no current standa...
Source: Chemical Senses - February 13, 2024 Category: Biochemistry Authors: Murray Parker Dirk H R Spennemann Jennifer Bond Source Type: research
