Cerebellum This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Correction: Cerebellar Volumetry in Ataxias: Relation to Ataxia Severity and Duration
Cerebellum. 2024 Mar 6. doi: 10.1007/s12311-024-01681-2. Online ahead of print.NO ABSTRACTPMID:38446346 | DOI:10.1007/s12311-024-01681-2 (Source: Cerebellum)
Source: Cerebellum - March 6, 2024 Category: Neuroscience Authors: M ónica Ferreira Tamara Schaprian David K ügler Martin Reuter Katharina Deike-Hoffmann Dagmar Timmann Thomas M Ernst Paola Giunti Hector Garcia-Moreno Bart van de Warrenburg Judith van Gaalen Jeroen de Vries Heike Jacobi Katharina Marie Steiner G ülin Source Type: research

Optimizing Communication in Ataxia: A Multifaceted Approach to Alternative and Augmentative Communication (AAC)
Cerebellum. 2024 Mar 7. doi: 10.1007/s12311-024-01675-0. Online ahead of print.ABSTRACTThe progression of multisystem neurodegenerative diseases such as ataxia significantly impacts speech and communication, necessitating adaptive clinical care strategies. With the deterioration of speech, Alternative and Augmentative Communication (AAC) can play an ever increasing role in daily life for individuals with ataxia. This review describes the spectrum of AAC resources available, ranging from unaided gestures and sign language to high-tech solutions like speech-generating devices (SGDs) and eye-tracking technology. Despite the a...
Source: Cerebellum - March 6, 2024 Category: Neuroscience Authors: Adam P Vogel Caroline Spencer Katie Burke Daniella de Bruyn Peter Gibilisco Scott Blackman Jennifer M Vojtech Thayabaran Kathiresan Source Type: research

CHARON: An Imaging-Based Diagnostic Algorithm to Navigate Through the Sea of Hereditary Degenerative Ataxias
Cerebellum. 2024 Mar 4. doi: 10.1007/s12311-024-01677-y. Online ahead of print.ABSTRACTThe complexity in diagnosing hereditary degenerative ataxias lies not only in their rarity, but also in the variety of different genetic conditions that can determine sometimes similar and overlapping clinical findings. In this light, Magnetic Resonance Imaging (MRI) plays a key role in the evaluation of these conditions, being a fundamental diagnostic tool needed not only to exclude other causes determining the observed clinical phenotype, but also to proper guide to an adequate genetic testing. Here, we propose an MRI-based diagnostic ...
Source: Cerebellum - March 4, 2024 Category: Neuroscience Authors: Alessandra Scaravilli Mario Tranfa Giuseppe Pontillo Bernard Brais Giovanna De Michele Roberta La Piana Francesco Sacc à Filippo Maria Santorelli Matthis Synofzik Arturo Brunetti Sirio Cocozza Source Type: research

Cerebello-Hippocampal Interactions in the Human Brain: A New Pathway for Insights Into Aging
Cerebellum. 2024 Mar 4. doi: 10.1007/s12311-024-01670-5. Online ahead of print.ABSTRACTThe cerebellum is recognized as being important for optimal behavioral performance across task domains, including motor function, cognition, and affect. Decades of work have highlighted cerebello-thalamo-cortical circuits, from both structural and functional perspectives. However, these circuits of interest have been primarily (though not exclusively) focused on targets in the cerebral cortex. In addition to these cortical connections, the circuit linking the cerebellum and hippocampus is of particular interest. Recently, there has been ...
Source: Cerebellum - March 4, 2024 Category: Neuroscience Authors: Jessica A Bernard Source Type: research

Structural Brain Correlates of Sleep Microstructure in Spinocerebellar Ataxia Type 2 and its Role on Clinical Phenotype
The objective of the study is to explore the relationship between sleep microstructure and brain atrophy in SCA2 and its role in the clinical phenotype. Fourteen SCA2 mutation carriers (7 pre-manifest and 7 manifest subjects) underwent polysomnographic, structural MRI, and clinical assessments. Particularly, markers of REM and non-REM sleep microstructure, measures of cerebellar and brainstem atrophy, and clinical scores were analyzed through correlation and mediation analyses. The sleep spindle activity exhibited a negative correlation with the number of trials required to complete the verbal memory test (VMT), and a posi...
Source: Cerebellum - March 4, 2024 Category: Neuroscience Authors: Roberto Rodr íguez-Labrada Nalia Canales-Ochoa Maria de Lourdes Galicia-Polo Edilia Cruz-Rivas Sandro Romanzetti Arnoy Pe ña-Acosta Anneli é Estupiñán-Rodríguez Yaime é Vázquez-Mojena Imis Dogan Georg Auburger Kathrin Reetz Luis Vel ázquez-Pérez Source Type: research

Disentangling Cerebellar and Parietal Contributions to Gait and Body Schema: A Repetitive Transcranial Magnetic Stimulation Study
This study aimed to identify distinguishing motor and cognitive features to disentangle PPC and cerebellar involvement in two sensorimotor-related functions: gait and body schema representation. Thirty healthy volunteers were enrolled and randomly assigned to PPC or cerebellar stimulation. Sham stimulation and 1 Hz-repetitive-Transcranial-Magnetic-Stimulation were delivered over P3 or cerebellum before a balance and a walking distance estimation task. Each trial was repeated with eyes open (EO) and closed (EC). Eight inertial measurement units recorded spatiotemporal and kinematic variables of gait. Instability increased i...
Source: Cerebellum - March 4, 2024 Category: Neuroscience Authors: Margherita Bertuccelli Patrizia Bisiacchi Alessandra Del Felice Source Type: research