Cerebellar Effects on Abnormal Psychomotor Function Are Mediated by Processing Speed in Psychosis Spectrum
Cerebellum. 2023 Aug 4. doi: 10.1007/s12311-023-01591-9. Online ahead of print.ABSTRACTPsychomotor disturbance has been identified as a key feature of psychotic disorders, with motor signs observed in upwards of 66% of unmedicated, first-episode patients. Aberrations in the cerebellum have been directly linked to sensorimotor processing deficits including processing speed, which may underly psychomotor disturbance in psychosis, though these brain-behavior-symptom relationships are unclear, in part due to within-diagnosis heterogeneity across these levels of analysis. In 339 psychosis patients (242 schizophrenia-spectrum, 9...
Source: Cerebellum - August 4, 2023 Category: Neuroscience Authors: Alexandra B Moussa-Tooks Jinyuan Liu Kristan Armstrong Baxter Rogers Neil D Woodward Stephan Heckers Source Type: research
Comparison of Two Therapeutic Approaches of Cerebellar Transcranial Direct Current Stimulation in a Sardinian Family Affected by Spinocerebellar Ataxia 38: a Clinical and Computerized 3D Gait Analysis Study
Cerebellum. 2023 Aug 4. doi: 10.1007/s12311-023-01590-w. Online ahead of print.ABSTRACTSpinocerebellar ataxia 38 (SCA 38) is a very rare autosomal dominant inherited disorder caused by a mutation in ELOV5 gene, specifically expressed in cerebellar Purkinje cells, encoding an enzyme involved in the synthesis of fatty acids. Seven symptomatic SCA 38 patients of a Sardinian family were administered 15 sessions of cerebellar anodal transcranial direct current stimulation (tDCS) in a cross-over study, employing deltoid cerebellar-only (C-tDCS) and cerebello-spinal (CS-tDCS) cathodal montage. Clinical evaluation was performed at...
Source: Cerebellum - August 4, 2023 Category: Neuroscience Authors: Angela Sanna Massimiliano Pau Giuseppina Pilia Micaela Porta Giulia Casu Valentina Secci Emanuele Cartella Alessandro Demattia Stefano Firinu Chiara Pau Antonio Milia Eleonora Cocco Paolo Tacconi Source Type: research
Cerebellar Effects on Abnormal Psychomotor Function Are Mediated by Processing Speed in Psychosis Spectrum
Cerebellum. 2023 Aug 4. doi: 10.1007/s12311-023-01591-9. Online ahead of print.ABSTRACTPsychomotor disturbance has been identified as a key feature of psychotic disorders, with motor signs observed in upwards of 66% of unmedicated, first-episode patients. Aberrations in the cerebellum have been directly linked to sensorimotor processing deficits including processing speed, which may underly psychomotor disturbance in psychosis, though these brain-behavior-symptom relationships are unclear, in part due to within-diagnosis heterogeneity across these levels of analysis. In 339 psychosis patients (242 schizophrenia-spectrum, 9...
Source: Cerebellum - August 4, 2023 Category: Neuroscience Authors: Alexandra B Moussa-Tooks Jinyuan Liu Kristan Armstrong Baxter Rogers Neil D Woodward Stephan Heckers Source Type: research
Comparison of Two Therapeutic Approaches of Cerebellar Transcranial Direct Current Stimulation in a Sardinian Family Affected by Spinocerebellar Ataxia 38: a Clinical and Computerized 3D Gait Analysis Study
Cerebellum. 2023 Aug 4. doi: 10.1007/s12311-023-01590-w. Online ahead of print.ABSTRACTSpinocerebellar ataxia 38 (SCA 38) is a very rare autosomal dominant inherited disorder caused by a mutation in ELOV5 gene, specifically expressed in cerebellar Purkinje cells, encoding an enzyme involved in the synthesis of fatty acids. Seven symptomatic SCA 38 patients of a Sardinian family were administered 15 sessions of cerebellar anodal transcranial direct current stimulation (tDCS) in a cross-over study, employing deltoid cerebellar-only (C-tDCS) and cerebello-spinal (CS-tDCS) cathodal montage. Clinical evaluation was performed at...
Source: Cerebellum - August 4, 2023 Category: Neuroscience Authors: Angela Sanna Massimiliano Pau Giuseppina Pilia Micaela Porta Giulia Casu Valentina Secci Emanuele Cartella Alessandro Demattia Stefano Firinu Chiara Pau Antonio Milia Eleonora Cocco Paolo Tacconi Source Type: research
Cerebellar Effects on Abnormal Psychomotor Function Are Mediated by Processing Speed in Psychosis Spectrum
Cerebellum. 2023 Aug 4. doi: 10.1007/s12311-023-01591-9. Online ahead of print.ABSTRACTPsychomotor disturbance has been identified as a key feature of psychotic disorders, with motor signs observed in upwards of 66% of unmedicated, first-episode patients. Aberrations in the cerebellum have been directly linked to sensorimotor processing deficits including processing speed, which may underly psychomotor disturbance in psychosis, though these brain-behavior-symptom relationships are unclear, in part due to within-diagnosis heterogeneity across these levels of analysis. In 339 psychosis patients (242 schizophrenia-spectrum, 9...
Source: Cerebellum - August 4, 2023 Category: Neuroscience Authors: Alexandra B Moussa-Tooks Jinyuan Liu Kristan Armstrong Baxter Rogers Neil D Woodward Stephan Heckers Source Type: research
