Palmitic acid-activated GPRs/KLF7/CCL2 pathway is involved in the crosstalk between bone marrow adipocytes and prostate cancer
Obesity-induced abnormal bone marrow microenvironment is one of the important risk element for bone metastasis in prostate cancer (PCa). The present study aimed to determine whether obesity-induced elevation i... (Source: BMC Cancer)
Source: BMC Cancer - January 15, 2024 Category: Cancer & Oncology Authors: Jingzhou Wang, Jie Liu, Chenggang Yuan, Bingqi Yang, Huai Pang, Keru Chen, Jiale Feng, Yuchun Deng, Xueting Zhang, Wei Li, Cuizhe Wang, Jianxin Xie and Jun Zhang Tags: Research Source Type: research
Prophylactic pectoralis major flap to compensate for increased risk of pharyngocutaneous fistula in laryngectomy patients with low skeletal muscle mass (PECTORALIS): study protocol for a randomized controlled trial
Total laryngectomy (TL) is a surgical procedure commonly performed on patients with advanced laryngeal or hypopharyngeal carcinoma. One of the most common postoperative complications following TL is the develo... (Source: BMC Cancer)
Source: BMC Cancer - January 15, 2024 Category: Cancer & Oncology Authors: Maartje A. van Beers, Caroline M. Speksnijder, Carla H. van Gils, Geert W.J. Frederix, Jan Willem Dankbaar and Remco de Bree Tags: Study Protocol Source Type: research
Novel model integrating computed tomography-based image markers with genetic markers for discriminating radiation pneumonitis in patients with unresectable stage III non-small cell lung cancer receiving radiotherapy: a retrospective multi-center radiogenomics study
Chemoradiotherapy is a critical treatment for patients with locally advanced and unresectable non-small cell lung cancer (NSCLC), and it is essential to identify high-risk patients as early as possible owing t... (Source: BMC Cancer)
Source: BMC Cancer - January 15, 2024 Category: Cancer & Oncology Authors: Jiaran Li, Li Li, Shanshan Tang, Qingxi Yu, Wenju Liu, Ning Liu, Fengchang Yang, Dexian Zhang and Shuanghu Yuan Tags: Research Source Type: research
Efficacy and safety of add-on mirogabalin to conventional therapy for the treatment of peripheral neuropathic pain after thoracic surgery: the multicenter, randomized, open-label ADMIT-NeP study
We examined the efficacy and saf... (Source: BMC Cancer)
Source: BMC Cancer - January 15, 2024 Category: Cancer & Oncology Authors: Takuro Miyazaki, Keitaro Matsumoto, Toshihiko Sato, Isao Sano, Katsuro Furukawa, Koichiro Shimoyama, Ryotaro Kamohara, Makoto Suzuki, Masamichi Kondou, Norihiko Ikeda, Shunsuke Tabata, Kazuhito Shiosakai and Takeshi Nagayasu Tags: Research Source Type: research
A phase Ib/II randomized, open-label drug repurposing trial of glutamate signaling inhibitors in combination with chemoradiotherapy in patients with newly diagnosed glioblastoma: the GLUGLIO trial protocol
Glioblastoma is the most common and most aggressive malignant primary brain tumor in adults. Glioblastoma cells synthesize and secrete large quantities of the excitatory neurotransmitter glutamate, driving epi... (Source: BMC Cancer)
Source: BMC Cancer - January 15, 2024 Category: Cancer & Oncology Authors: Maximilian Mastall, Patrick Roth, Andrea Bink, Angela Fischer Maranta, Heinz L äubli, Andreas Felix Hottinger, Thomas Hundsberger, Denis Migliorini, Adrian Ochsenbein, Katharina Seystahl, Lukas Imbach, Tibor Hortobagyi, Leonhard Held, Michael Weller and Tags: Study Protocol Source Type: research
Hypofractionated radiotherapy for refractory or relapsed aggressive B-cell lymphoma in the rituximab era
Radiotherapy (RT) is an effective and available local treatment for patients with refractory or relapsed (R/R) aggressive B-cell lymphomas. However, the value of hypofractionated RT in this setting has not bee... (Source: BMC Cancer)
Source: BMC Cancer - January 13, 2024 Category: Cancer & Oncology Authors: Cheng Huang, Tian-Lan Tang, Yan-Yan Qiu, Yu-Ping Lin, Si-Lin Chen, Rui-Zhi Zhao, Gui-Qing Shi, Si-Qin Liao, Jin-Hua Chen, Hai-Ying Fu, Jian-Zhi Liu, Ben-Hua Xu, Ting-Bo Liu and Yong Yang Tags: Research Source Type: research
Unraveling cervical cancer screening dilemmas: histopathological insights from VIA and LEEP at bugando medical centre, Mwanza
The single-visit strategy, also known as the “screen-and-treat” approach, is widely used to screen for cervical cancer in low- and middle-income countries. The screen-and-treat approach leads to unnecessary or... (Source: BMC Cancer)
Source: BMC Cancer - January 12, 2024 Category: Cancer & Oncology Authors: Godfrey K. Kaizilege, Edgar Ndaboine, Clotilda Chuma, Fridolin Mujuni, Richard Kiritta, Dismas Matovelo, Oscar Ottoman, Edrick Elias, Nestory Masalu, Benson R. Kidenya and Humphrey D. Mazigo Tags: Research Source Type: research
Survival outcome of different treatment sequences in patients with locally advanced and metastatic pancreatic cancer
Despite some therapeutic advances, improvement in survival rates of unresectable and/or metastatic pancreatic ductal adenocarcinoma (PDAC) has been minimal over recent decade. We aimed to evaluate the impact o... (Source: BMC Cancer)
Source: BMC Cancer - January 12, 2024 Category: Cancer & Oncology Authors: Mengjiao Fan, Guochao Deng, Yue Ma, Haiyan Si, Zhikuan Wang and Guanghai Dai Tags: Research Source Type: research
Advanced-stage presentation of cancer at the time of diagnosis and its associated factors among adult cancer patients at Northwest Amhara comprehensive specialized hospitals, Northwest Ethiopia 2022
Screening of cancer is the maximum effort and critical element for providing health related care in order to decrease cancer related dealt because of the disease burden is in its advanced stages. Unfortunately... (Source: BMC Cancer)
Source: BMC Cancer - January 12, 2024 Category: Cancer & Oncology Authors: Likinaw Abebaw Wassie, Chilot Kassa Mekonnen, Yenework Mulu Tiruneh, Mamaru melkam, Eyayaw Ashete Belachew and Alebachew Ferede Zegeye Tags: Research Source Type: research
An integrated model incorporating deep learning, hand-crafted radiomics and clinical and US features to diagnose central lymph node metastasis in patients with papillary thyroid cancer
To evaluate the value of an integrated model incorporating deep learning (DL), hand-crafted radiomics and clinical and US imaging features for diagnosing central lymph node metastasis (CLNM) in patients with p... (Source: BMC Cancer)
Source: BMC Cancer - January 12, 2024 Category: Cancer & Oncology Authors: Yang Gao, Weizhen Wang, Yuan Yang, Ziting Xu, Yue Lin, Ting Lang, Shangtong Lei, Yisheng Xiao, Wei Yang, Weijun Huang and Yingjia Li Tags: Research Source Type: research
“How can a woman live without having a breast?”: challenges related to mastectomy in Ethiopia
Although mastectomy is the standard treatment modality for breast cancer patients in Ethiopia, our previous study revealed that one in five patients do not receive the recommended procedure, half due to patien... (Source: BMC Cancer)
Source: BMC Cancer - January 11, 2024 Category: Cancer & Oncology Authors: Abigiya Wondimagegnehu, Solomon Teferra, Mathewos Assefa, Bradley Zebrack, Adamu Addissie and Eva J. Kantelhardt Tags: Research Source Type: research
Amputation in patients with extremity soft tissue sarcoma: the experience of an East Asian referral center
This study aimed to investigate the characteristics and clinical outcomes in a series of patients with extremity soft tissue sarcoma (STS) who underwent amputation at a large East Asian referral center. (Source: BMC Cancer)
Source: BMC Cancer - January 11, 2024 Category: Cancer & Oncology Authors: Yongsung Kim, Han-Soo Kim and Ilkyu Han Tags: Research Source Type: research
Prognostic value of plasma microRNAs for non-small cell lung cancer based on data mining models
As biomarkers, microRNAs (miRNAs) are closely associated with the occurrence, progression, and prognosis of non-small cell lung cancer (NSCLC). However, the prognostic predictive value of miRNAs in NSCLC has r... (Source: BMC Cancer)
Source: BMC Cancer - January 10, 2024 Category: Cancer & Oncology Authors: Mengqing Yan, Wenjun Kang, Xiaohua Liu, Bin Yang, Na Sun, Yongli Yang and Wei Wang Tags: Research Source Type: research
Identification of CD8+ T-cell exhaustion signatures for prognosis in HBV-related hepatocellular carcinoma patients by integrated analysis of single-cell and bulk RNA-sequencing
In this study, we aimed to inv... (Source: BMC Cancer)
Source: BMC Cancer - January 10, 2024 Category: Cancer & Oncology Authors: Jianhao Li, Han Chen, Lang Bai and Hong Tang Tags: Research Source Type: research
Short-term outcomes and long-term quality of life of reconstruction methods after proximal gastrectomy: a systematic review and meta-analysis
The optimal reconstruction method after proximal gastrectomy remains unclear. This systematic review and meta-analysis aimed to compare the short-term outcomes and long-term quality of life of various reconstr... (Source: BMC Cancer)
Source: BMC Cancer - January 10, 2024 Category: Cancer & Oncology Authors: Bailong Li, Yinkui Wang, Baocong Li, Fei Shan and Ziyu Li Tags: Research Source Type: research
