Detection of circulating tumor DNA in plasma of patients with primary CNS lymphoma by digital droplet PCR
Primary central nervous system lymphoma (PCNSL) are rare mature B-cell lymphoproliferative diseases characterized by a high incidence of MYD88 L265P and CD79B Y196 hotspot mutations. Diagnosis of PCNSL can be ... (Source: BMC Cancer)
Source: BMC Cancer - April 2, 2024 Category: Cancer & Oncology Authors: Yujie Zhong, Geok Wee Tan, Johanna Bult, Nick Veltmaat, Wouter Plattel, Joost Kluiver, Roelien Enting, Arjan Diepstra, Anke van den Berg and Marcel Nijland Tags: Research Source Type: research
Knockdown of NCAPD3 inhibits the tumorigenesis of non-small cell lung cancer by regulation of the PI3K/Akt pathway
Accumulating evidence indicates that aberrant non-SMC condensin II complex subunit D3 (NCAPD3) is associated with carcinogenesis of various cancers. Nevertheless, the biological role of NCAPD3 in the pathogene... (Source: BMC Cancer)
Source: BMC Cancer - April 2, 2024 Category: Cancer & Oncology Authors: Fan Yang, Yunfeng Zheng, Qiong Luo, Suyun Zhang, Sheng Yang and Xiangqi Chen Tags: Research Source Type: research
Population-based BRCA germline mutation screening in the Han Chinese identifies individuals at risk of BRCA mutation-related cancer: experience from a clinical diagnostic center from greater Shanghai area
Deleterious BRCA1/2 (BRCA) mutation raises the risk for BRCA mutation-related malignancies, including breast, ovarian, prostate, and pancreatic cancer. Germline variation of BRCA exhibits substantial ethnical div... (Source: BMC Cancer)
Source: BMC Cancer - April 2, 2024 Category: Cancer & Oncology Authors: Zhiyuan Wu, Qingyun Zhang, Yiting Jin, Xinju Zhang, Yanli Chen, Can Yang, Xuemei Tang, Haowen Jiang, Xiaoyi Wang, Xinli Zhou, Feng Yu, Bing Wang and Ming Guan Tags: Research Source Type: research
The podoplanin-CLEC-2 interaction promotes platelet-mediated melanoma pulmonary metastasis
This study aimed to investigate the role of the PDPN-platelet CLEC-2 interaction in melanoma pulmonar... (Source: BMC Cancer)
Source: BMC Cancer - April 1, 2024 Category: Cancer & Oncology Authors: Minjia Sheng, Ran Sun, Jianxin Fu and Gao Lu Tags: Research Source Type: research
Cancer-associated fibroblasts drive colorectal cancer cell progression through exosomal miR-20a-5p-mediated targeting of PTEN and stimulating interleukin-6 production
This study evaluated the clinical relevance of a set of five serum-derived circulating microRNAs (miRNAs) in colorectal cancer (CRC). Additionally, we investigated the role of miR-20a-5p released by exosomes d... (Source: BMC Cancer)
Source: BMC Cancer - April 1, 2024 Category: Cancer & Oncology Authors: Mahsa Ghofrani-Shahpar, Katayoon Pakravan, Ehsan Razmara, Faezeh Amooie, Mojdeh Mahmoudian, Masoumeh Heshmati and Sadegh Babashah Tags: Research Source Type: research
Down-regulated HHLA2 enhances neoadjuvant immunotherapy efficacy in patients with non-small cell lung cancer (NSCLC) with chronic obstructive pulmonary disease (COPD)
The objective of this study was t... (Source: BMC Cancer)
Source: BMC Cancer - March 29, 2024 Category: Cancer & Oncology Authors: Ao Zeng, Yanze Yin, Zhilong Xu, Abudumijiti Abuduwayiti, Fujun Yang, Mohammed Saud Shaik, Chao Wang, Keyi Chen, Chao Wang, Xinyun Fang and Jie Dai Tags: Research Source Type: research
mFOLFIRINOX versus mFOLFOX 6 as adjuvant treatment for high-risk stage III colon cancer - the FROST trial: study protocol for a multicenter, randomized controlled, phase II trial
High-risk stage III colon cancer has a considerably poorer prognosis than stage II and low-risk stage III colon cancers. Nevertheless, most guidelines recommend similar adjuvant treatment approaches for all th... (Source: BMC Cancer)
Source: BMC Cancer - March 29, 2024 Category: Cancer & Oncology Authors: Kyung-Ha Lee, In Jun Yang, Gi Won Ha, Jaeim Lee, Youn Young Park, Suk Hwan Lee, Jong Min Lee, Jung Hoon Bae, Eun Jung Park, Hyungjin Kim, Keun Young Kim, Sanghyung An, Ik Yong Kim and Ji Yeon Kim Tags: Study Protocol Source Type: research
Effects of physical and psychological symptoms on cancer-related fatigue among esophageal cancer patients
Cancer-related fatigue (CRF) is considered one of the most prevalent and distressing symptoms among cancer patients and may vary among patients with different cancer types. However, few studies have explored t... (Source: BMC Cancer)
Source: BMC Cancer - March 29, 2024 Category: Cancer & Oncology Authors: ChunYing Cui, Lie Wang and XiaoXi Wang Tags: Research Source Type: research
Retraction Note: KRAS activation in gastric cancer stem-like cells promotes tumor angiogenesis and metastasis
(Source: BMC Cancer)
Source: BMC Cancer - March 28, 2024 Category: Cancer & Oncology Authors: Changhwan Yoon, Jun Lu, Yukyung Jun, Yun-Suhk Suh, Bang-Jin Kim, Jacob E. Till, Jong Hyun Kim, Sara H. Keshavjee, Sandra Ryeom and Sam S. Yoon Tags: Retraction Note Source Type: research
Immune checkpoint inhibitor plus chemotherapy as first-line treatment for non-small cell lung cancer with malignant pleural effusion: a retrospective multicenter study
Immune checkpoint inhibitors (ICI) combined with chemotherapy are efficacious for treating advanced non-small cell lung cancer (NSCLC); however, the effectiveness of this approach in the malignant pleural effu... (Source: BMC Cancer)
Source: BMC Cancer - March 28, 2024 Category: Cancer & Oncology Authors: Qi Wei, Taibing Deng, Junhua Wu, Hao Zeng, Chang Qi, Sihan Tan, Yuanyuan Zhang, Qin Huang, Xin Pu, Weiguo Xu, Weimin Li, Panwen Tian and Yalun Li Tags: Research Source Type: research
Patterns and treatment outcomes of primary bone tumors in children treated at tertiary referral hospital, Ethiopia
Bone tumors account for approximately 6% of all cancers in children. Malignant bone tumors, commonly occurring in children and adolescents, are associated with high mortality and morbidity. The overall surviva... (Source: BMC Cancer)
Source: BMC Cancer - March 28, 2024 Category: Cancer & Oncology Authors: Temesgen Lingerih, Sewagegn Yeshiwas, Abdulkadir Mohamedsaid and Gashaw Arega Tags: Research Source Type: research
Characterization of tumoricidal activities mediated by a novel immune cell regimen composing interferon-producing killer dendritic cells and tumor-specific cytotoxic T lymphocytes
Although immune cell therapy has long been used for treating solid cancer, its efficacy remains limited. Interferon (IFN)-producing killer dendritic cells (IKDCs) exhibit cytotoxicity and present antigens to r... (Source: BMC Cancer)
Source: BMC Cancer - March 28, 2024 Category: Cancer & Oncology Authors: Chih-Hao Fang, Wen-Fang Cheng, Ya-Fang Cheng, Keng-Li Lan and Jan-Mou Lee Tags: Research Source Type: research
Transarterial chemoembolization with molecular targeted therapies plus camrelizumab for recurrent hepatocellular carcinoma
The safety and efficacy of transarterial chemoembolization plus molecular targeted therapy (MTT) combined with immune checkpoint inhibitors (ICIs) in primary liver cancer have been demonstrated. However, the e... (Source: BMC Cancer)
Source: BMC Cancer - March 27, 2024 Category: Cancer & Oncology Authors: Changlong Hou, Baizhu Xiong, Lei Zhou, Yipeng Fei, Changgao Shi, Xianhai Zhu, Tao Xie and Yulin Wu Tags: Research Source Type: research
Association of hormone receptors and human epidermal growth factor receptor-2/neu expressions with clinicopathologic factors of breast carcinoma: a cross-sectional study in a tertiary care hospital, Kabul, Afghanistan
Breast cancer (BC) is one of the major causes of death worldwide. It is the most common cause of death before the age of 70 years. The incidence and mortality of BC are rapidly increasing, posing great challen... (Source: BMC Cancer)
Source: BMC Cancer - March 27, 2024 Category: Cancer & Oncology Authors: Esmatullah Esmat, Ahmed Maseh Haidary, Ramin Saadaat, Syeda Naghma Rizvi, Syeda Aleena, Mujtaba Haidari, Sayed Murtaza Sadat Hofiani, Nasrin Hussaini, Ahmadullah Hakimi, Abdullatif Khairy and Jamshid Abdul-Ghafar Tags: Research Source Type: research
Assessing the use of anti-PD1 monotherapy as adjuvant therapy and determinants of treatment choice in stage III cutaneous melanoma in the US
The objective of this study was to describe real-world adjuvant therapy (AT) use by disease substage and assess determinants of treatment choice among patients with stage III melanoma. (Source: BMC Cancer)
Source: BMC Cancer - March 27, 2024 Category: Cancer & Oncology Authors: Eric D. Whitman, Todor I. Totev, Shan Jiang, Wilson L. da Costa Jr., Dmitri Grebennik, Hongjue Wang, Andra-Ecaterina Boca and Rajeev Ayyagari Tags: Research Source Type: research
