Identification and characterization of stromal-like cells with CD207+/low CD1a+/low phenotype derived from histiocytic lesions – a perspective in vitro model for drug testing
Histiocytoses are rare disorders manifested by increased proliferation of pathogenic myeloid cells sharing histological features with macrophages or dendritic cells and accumulating in various organs, i.a., bo... (Source: BMC Cancer)
Source: BMC Cancer - February 12, 2024 Category: Cancer & Oncology Authors: Agnieszka Śmieszek, Klaudia Marcinkowska, Zofia Małas, Mateusz Sikora, Martyna Kępska, Beata A. Nowakowska, Marta Deperas, Marta Smyk, Carlos Rodriguez-Galindo and Anna Raciborska Tags: Research Source Type: research

Nomogram incorporating prognostic immune-inflammatory-nutritional score for survival prediction in pancreatic cancer: a retrospective study
Prognosis prediction for pancreatic cancer has always been difficult in clinical practice because of its high heterogeneity and mortality. The aim of the study was to assess the value of prognostic immune-infl... (Source: BMC Cancer)
Source: BMC Cancer - February 12, 2024 Category: Cancer & Oncology Authors: Jie Yang, Hongkun Zhou, Huangbao Li, Fengqing Zhao and Kun Tong Tags: Research Source Type: research

Inflammatory markers predict survival in patients with postoperative urothelial carcinoma receiving tislelizumab (PD-1 inhibitor) adjuvant therapy
In the management of urothelial carcinoma, patient selection for immunotherapy, particularly with immune checkpoint inhibitors such as PD-1 (programmed cell death protein 1), is important for treatment effica... (Source: BMC Cancer)
Source: BMC Cancer - February 12, 2024 Category: Cancer & Oncology Authors: Meng Yang, Jingwen Zhang, Dongqun Wei, Tianyi Yu, Zeyu Chen, Xin Liu and Haitao Zhu Tags: Research Source Type: research

Radiation pneumonitis after concurrent aumolertinib and thoracic radiotherapy in EGFR-mutant non-small cell lung cancer patients
The superior efficacy of concurrent thoracic radiotherapy (TRT) and epidermal growth factor receptor tyrosine kinase inhibitors (EGFR-TKIs) has been proven in locally advanced and advanced non-small cell lung ... (Source: BMC Cancer)
Source: BMC Cancer - February 12, 2024 Category: Cancer & Oncology Authors: Hanjing Yin, Wenxiao Jia, Jinming Yu and Hui Zhu Tags: Research Source Type: research

Oridonin-induced ferroptosis and apoptosis: a dual approach to suppress the growth of osteosarcoma cells
Osteosarcoma (OS) is one of the most common aggressive bone malignancy tumors in adolescents. With the application of new chemotherapy regimens, finding new and effective anti-OS drugs to coordinate program im... (Source: BMC Cancer)
Source: BMC Cancer - February 12, 2024 Category: Cancer & Oncology Authors: Feifan Zhang, Yang Hao, Ning Yang, Man Liu, Yage Luo, Ying Zhang, Jian Zhou, Hongjian Liu and Jitian Li Tags: Research Source Type: research

Impacts of systemic treatments on health-related quality of life for patients with metastatic colorectal cancer: a systematic review and network meta-analysis
There is limited evidence of comparative results among different treatments regarding impacts of Health-Related Quality of Life (HRQoL) for patients with metastatic colorectal cancer (mCRC). We aimed to compar... (Source: BMC Cancer)
Source: BMC Cancer - February 9, 2024 Category: Cancer & Oncology Authors: Yunlin Jiang, Mingye Zhao, Wenxi Tang and Xueping Zheng Tags: Research Source Type: research

Comparison of partitioned survival modeling with state transition modeling approaches with or without consideration of brain metastasis: a case study of Osimertinib versus pemetrexed-platinum
The partitioned survival model (PSM) and the state transition model (STM) are widely used in cost-effectiveness analyses of anticancer drugs. Using different modeling approaches with or without consideration o... (Source: BMC Cancer)
Source: BMC Cancer - February 9, 2024 Category: Cancer & Oncology Authors: Yoon-Bo Shim, Byeong-Chan Oh, Eui-Kyung Lee and Mi-Hai Park Tags: Research Source Type: research

Impact of preoperative transcatheter arterial chemoembolization (TACE) on postoperative long-term survival in patients with nonsmall hepatocellular carcinoma: a propensity score matching analysis
The purpose of this propensity score matching (PSM) analysis was to compare the effects of preoperative transcatheter arterial chemoembolization (TACE) and non-TACE on the long-term survival of patients who un... (Source: BMC Cancer)
Source: BMC Cancer - February 9, 2024 Category: Cancer & Oncology Authors: Run Hu, Jie Xu, Hongxiang Wang, Jiaguo Wang, Kai Lei, Xiaoping Zhao, Huizhi Zhang, Ke You and Zuojin Liu Tags: Research Source Type: research

Identifying optimal ALK inhibitors in first- and second-line treatment of patients with advanced ALK-positive non-small-cell lung cancer: a systematic review and network meta-analysis
To compare the efficacy, safety and effects on quality of life of different ALK-inhibitors for global and Asian patients with advanced ALK-positive non-small-cell lung cancer (NSCLC). (Source: BMC Cancer)
Source: BMC Cancer - February 8, 2024 Category: Cancer & Oncology Authors: Mingye Zhao, Taihang Shao, Hanqiao Shao, Caicun Zhou and Wenxi Tang Tags: Research Source Type: research

Multi-omics sequencing revealed endostar combined with cisplatin treated non small cell lung cancer via anti-angiogenesis
Endostar, an anti-angiogenic drug, has been approved for treating non-small cell lung cancer (NSCLC). At present, endostar combined with radiotherapy or chemotherapy has achieved ideal results in the treatment... (Source: BMC Cancer)
Source: BMC Cancer - February 8, 2024 Category: Cancer & Oncology Authors: Yufei Wang and Hong Ren Tags: Research Source Type: research

A promising target for breast cancer: B7-H3
Breast cancer (BC) is the second-leading factor of mortality for women globally and is brought on by a variety of genetic and environmental causes. The conventional treatments for this disease have limitations... (Source: BMC Cancer)
Source: BMC Cancer - February 7, 2024 Category: Cancer & Oncology Authors: Ying Jiang, Jiayu Liu, Lingyan Chen, Zhiwen Qian and Yan Zhang Tags: Review Source Type: research

Anticipated time to seek medical advice for possible lung cancer symptoms and barriers to timely presentation in Palestine: a national cross-sectional study
This study explored the anticipated time to seek medical advice for possible LC symptoms and barriers to early presentation i... (Source: BMC Cancer)
Source: BMC Cancer - February 7, 2024 Category: Cancer & Oncology Authors: Mohamedraed Elshami, Nawras Sawafta, Ahmad Mansour, Mohammed Alser, Ibrahim Al-Slaibi, Hanan Abukmail, Hanan Shurrab, Shahd Qassem, Faten Darwish Usrof, Malik Alruzayqat, Wafa Aqel, Roba Nairoukh, Rahaf Kittaneh, Yousef Mahmoud Nimer Habes, Obaida Ghanim, Tags: Research Source Type: research

Development and validation of a nomogram for predicting overall survival in patients with sinonasal mucosal melanoma
This study was designed to identify prognostic factors and establish a nomogram model to predict the overall survi... (Source: BMC Cancer)
Source: BMC Cancer - February 7, 2024 Category: Cancer & Oncology Authors: Zhenzhen Zhu, Weiqing Wang, Yang Zha, Xiaowei Wang, Surita Aodeng, Lei Wang, Yuzhuo Liu and Wei Lv Tags: Research Source Type: research

Drug-resistant profiles of extracellular vesicles predict therapeutic response in TNBC patients receiving neoadjuvant chemotherapy
Predicting tumor responses to neoadjuvant chemotherapy (NAC) is critical for evaluating prognosis and designing treatment strategies for patients with breast cancer; however, there are no reliable biomarkers t... (Source: BMC Cancer)
Source: BMC Cancer - February 7, 2024 Category: Cancer & Oncology Authors: Min Woo Kim, Hyojung Lee, Suji Lee, Sol Moon, Young Kim, Joon Ye Kim, Seung Il Kim and Jee Ye Kim Tags: Research Source Type: research

Experiences and perceptions of men following breast cancer diagnosis: a mixed method systematic review
Men with breast cancer experience unique physical and emotional challenges. However, a thorough understanding of these experiences including the psychosocial effects and supportive care needs have received les... (Source: BMC Cancer)
Source: BMC Cancer - February 6, 2024 Category: Cancer & Oncology Authors: Mary Abboah-Offei, Jonathan Bayuo, Yakubu Salifu, Oladayo Afolabi and Theophilus N. Akudjedu Tags: Research Source Type: research