The efficacy and safety of vincristine, irinotecan and anlotinib in Epithelioid Sarcoma
Epithelioid sarcoma is a rare soft tissue sarcoma characterized by SMARCB1/INI1 deficiency. Much attention has been paid to the selective EZH2 inhibitor tazemetostat, where other systemic treatments are genera... (Source: BMC Cancer)
Source: BMC Cancer - February 3, 2024 Category: Cancer & Oncology Authors: Lu Xie, Xin Sun, Jie Xu, Xin Liang, Kuisheng Liu, Kunkun Sun, Rongli Yang, Xiaodong Tang and Wei Guo Tags: Research Source Type: research
The effects of oxaliplatin-based adjuvant chemotherapy in high-risk stage II colon cancer with mismatch repair-deficient: a retrospective study
For high-risk stageIImismatch repair deficient (dMMR) colon cancers, the benefit of adjuvant chemotherapy remains debatable. The principal aim of this study was to evaluate the prognostic value of high-risk fa... (Source: BMC Cancer)
Source: BMC Cancer - February 2, 2024 Category: Cancer & Oncology Authors: Leen Liao, Jinghua Tang, Zhigang Hong, Wu Jiang, Yuan Li, Lingheng Kong, Kai Han, Zhenlin Hou, Chenzhi Zhang, Chi Zhou, Linjie Zhang, Qiaoqi Sui, Binyi Xiao, Weijian Mei, Jiehai Yu, Wanjun Yang & hellip; Tags: Research Source Type: research
High serum proteinase-3 levels predict poor progression-free survival and lower efficacy of bevacizumab in metastatic colorectal cancer
This study aimed to analy... (Source: BMC Cancer)
Source: BMC Cancer - February 2, 2024 Category: Cancer & Oncology Authors: Kei Furuya, Masao Nakajima, Ryouichi Tsunedomi, Yuki Nakagami, Ming Xu, Hiroto Matsui, Yukio Tokumitsu, Yoshitaro Shindo, Yusaku Watanabe, Shinobu Tomochika, Noriko Maeda, Michihisa Iida, Nobuaki Suzuki, Shigeru Takeda, Shoichi Hazama, Tatsuya Ioka & hell Tags: Research Source Type: research
LncRNA RPARP-AS1 promotes the progression of osteosarcoma cells through regulating lipid metabolism
Osteosarcoma (OS) is a highly malignant tumor, and its dysregulated lipid metabolism is associated with tumorigenesis and unfavorable prognosis. Interestingly, long noncoding RNAs (lncRNAs) have emerged as piv... (Source: BMC Cancer)
Source: BMC Cancer - February 2, 2024 Category: Cancer & Oncology Authors: Feng Cai, Luhua Liu, Yuan Bo, Wenjing Yan, Xuchang Tao, Yuanxiang Peng, Zhiping Zhang, Qi Liao and Yangyan Yi Tags: Research Source Type: research
Hypoxia-induced miR-181a-5p up-regulation reduces epirubicin sensitivity in breast cancer cells through inhibiting EPDR1/TRPC1 to activate PI3K/AKT signaling pathway
Breast carcinoma (BC) ranks as a predominant malignancy and constitutes the second principal cause of mortality among women globally. Epirubicin stands as the drug of choice for BC therapeutics. Nevertheless, ... (Source: BMC Cancer)
Source: BMC Cancer - February 2, 2024 Category: Cancer & Oncology Authors: Yunwei Zhang, Yunping Guan, Xinyu Zheng and Chenyang Li Tags: Research Source Type: research
Sociodemographic characteristics and their association with survival in women with cervical cancer
In 2020, the highest incidence and mortality from cervical cancer (CC) were detected in low and middle-income countries. CC remains a health problem for women living in them. In Mexico, CC ranks second in canc... (Source: BMC Cancer)
Source: BMC Cancer - February 1, 2024 Category: Cancer & Oncology Authors: Lucely Cetina-P érez, Julissa Luvián-Morales, Merari Delgadillo-González, Denisse Castro-Eguiluz, Tatiana Galicia-Carmona, Kely Rely, Rita Vaca González, Gabriela Lugo-Martínez, Nadia García-Barrientos and Antonio Nateras Tags: Research Source Type: research
The diagnostic potential of miR-196a-1 in colorectal cancer
Colorectal cancer (CRC) is a common malignancy worldwide. MicroRNAs (miRNAs) are important epigenetic alterations that notably impact various physiological and pathological processes by acting as negative regu... (Source: BMC Cancer)
Source: BMC Cancer - February 1, 2024 Category: Cancer & Oncology Authors: Bayan Mehrjoei, Lida Haghnazari, Homayoon Bashiri and Nayebali Rezvani Tags: Research Source Type: research
Unveiling promising breast cancer biomarkers: an integrative approach combining bioinformatics analysis and experimental verification
Breast cancer remains a significant health challenge worldwide, necessitating the identification of reliable biomarkers for early detection, accurate prognosis, and targeted therapy. (Source: BMC Cancer)
Source: BMC Cancer - January 31, 2024 Category: Cancer & Oncology Authors: Ali Golestan, Ahmad Tahmasebi, Nafiseh Maghsoodi, Seyed Nooreddin Faraji, Cambyz Irajie and Amin Ramezani Tags: Research Source Type: research
Systematic analysis of the role of LDHs subtype in pan-cancer demonstrates the importance of LDHD in the prognosis of hepatocellular carcinoma patients
Lactate dehydrogenase (LDHs) is an enzyme involved in anaerobic glycolysis, including LDHA, LDHB, LDHC and LDHD. Given the regulatory role in the biological progression of certain tumors, we analyzed the role ... (Source: BMC Cancer)
Source: BMC Cancer - January 31, 2024 Category: Cancer & Oncology Authors: Shengnan Wang, Xingwei Wu, Xiaoming Wu, Jin Cheng, Qianyi Chen and Zhilin Qi Tags: Research Source Type: research
G6PD and machine learning algorithms as prognostic and diagnostic indicators of liver hepatocellular carcinoma
Liver Hepatocellular carcinoma (LIHC) exhibits a high incidence of liver cancer with escalating mortality rates over time. Despite this, the underlying pathogenic mechanism of LIHC remains poorly understood. (Source: BMC Cancer)
Source: BMC Cancer - January 31, 2024 Category: Cancer & Oncology Authors: Fei Li, Boshen Wang, Hao Li, Lu Kong and Baoli Zhu Tags: Research Source Type: research
Cardiovascular health assessment in routine cancer follow-up in community settings: survivor risk awareness and perspectives
Guidelines recommend cardiovascular risk assessment and counseling for cancer survivors. For effective implementation, it is critical to understand survivor cardiovascular health (CVH) profiles and perspective... (Source: BMC Cancer)
Source: BMC Cancer - January 31, 2024 Category: Cancer & Oncology Authors: Kathryn E. Weaver, Emily V. Dressler, Sydney Smith, Chandylen L. Nightingale, Heidi D. Klepin, Simon Craddock Lee, Brian J. Wells, W. Gregory Hundley, Joseph A. DeMari, Sarah N. Price and Randi E. Foraker Tags: Research Source Type: research
Feasibility and safety of laparoscopic radical cystectomy for male octogenarians with muscle-invasive bladder cancer
This study was designed to evaluate the safety and feasibility of laparoscopic radical cystectomy (LRC) for male octogenarian patients with muscle-invasive bladder cancer (MIBC). Briefly, a total of 57 male oc... (Source: BMC Cancer)
Source: BMC Cancer - January 31, 2024 Category: Cancer & Oncology Authors: Dong-liang Pan, Lu-fang Zhang, Xiao-jian Li, Ke-ping Zhang, Peng-fei Gao, Bing Yang and Ning-chen Li Tags: Research Source Type: research
LOGGIC/FIREFLY-2: a phase 3, randomized trial of tovorafenib vs. chemotherapy in pediatric and young adult patients with newly diagnosed low-grade glioma harboring an activating RAF alteration
Pediatric low-grade glioma (pLGG) is essentially a single pathway disease, with most tumors driven by genomic alterations affecting the mitogen-activated protein kinase/ERK (MAPK) pathway, predominantly KIAA1549:... (Source: BMC Cancer)
Source: BMC Cancer - January 30, 2024 Category: Cancer & Oncology Authors: Cornelis M. van Tilburg, Lindsay B. Kilburn, S ébastien Perreault, Rene Schmidt, Amedeo A. Azizi, Ofelia Cruz-Martínez, Michal Zápotocký, Katrin Scheinemann, Antoinette Y. N. Schouten-van Meeteren, Astrid Sehested, Enrico Opocher, Pablo Hernáiz Driev Tags: Study Protocol Source Type: research
Physician-brief advice for promoting smoking cessation among cancer patients on treatment in low and middle-income countries: a scoping review
Physician-brief advice has been utilized in high-income countries to promote smoking cessation among cancer patients. Empirical evidence on its effectiveness among cancer patients in low and middle-income coun... (Source: BMC Cancer)
Source: BMC Cancer - January 30, 2024 Category: Cancer & Oncology Authors: Olayinka Stephen Ilesanmi, Babalola Faseru, Aanuoluwapo Adeyimika Afolabi, Olukemi Odukoya, Olalekan Ayo-Yusuf, Folahanmi Akinsolu, Akindele Olupelumi Adebiyi and William K. Evans Tags: Research Source Type: research
Development and validation of a 18F-FDG PET/CT radiomics nomogram for predicting progression free survival in locally advanced cervical cancer: a retrospective multicenter study
The existing staging system cannot meet the needs of accurate survival prediction. Accurate survival prediction for locally advanced cervical cancer (LACC) patients who have undergone concurrent radiochemother... (Source: BMC Cancer)
Source: BMC Cancer - January 30, 2024 Category: Cancer & Oncology Authors: Huiling Liu, Yongbin Cui, Cheng Chang, Zichun Zhou, Yalin Zhang, Changsheng Ma, Yong Yin and Ruozheng Wang Tags: Research Source Type: research
