Inflammation of some visceral sensory systems and autonomic dysfunction in cardiovascular disease
Auton Neurosci. 2023 Dec 7;251:103137. doi: 10.1016/j.autneu.2023.103137. Online ahead of print.ABSTRACTThe sensitization and hypertonicity of visceral afferents are highly relevant to the development and progression of cardiovascular and respiratory disease states. In this review, we described the evidence that the inflammatory process regulates visceral afferent sensitivity and tonicity, affecting the control of the cardiovascular and respiratory system. Some inflammatory mediators like nitric oxide, angiotensin II, endothelin-1, and arginine vasopressin may inhibit baroreceptor afferents and contribute to the baroreflex...
Source: Autonomic Neuroscience - December 17, 2023 Category: Neuroscience Authors: R M Lataro F Brognara R Iturriaga J F R Paton Source Type: research

Inflammation of some visceral sensory systems and autonomic dysfunction in cardiovascular disease
Auton Neurosci. 2023 Dec 7;251:103137. doi: 10.1016/j.autneu.2023.103137. Online ahead of print.ABSTRACTThe sensitization and hypertonicity of visceral afferents are highly relevant to the development and progression of cardiovascular and respiratory disease states. In this review, we described the evidence that the inflammatory process regulates visceral afferent sensitivity and tonicity, affecting the control of the cardiovascular and respiratory system. Some inflammatory mediators like nitric oxide, angiotensin II, endothelin-1, and arginine vasopressin may inhibit baroreceptor afferents and contribute to the baroreflex...
Source: Autonomic Neuroscience - December 17, 2023 Category: Neuroscience Authors: R M Lataro F Brognara R Iturriaga J F R Paton Source Type: research

Inflammation of some visceral sensory systems and autonomic dysfunction in cardiovascular disease
Auton Neurosci. 2023 Dec 7;251:103137. doi: 10.1016/j.autneu.2023.103137. Online ahead of print.ABSTRACTThe sensitization and hypertonicity of visceral afferents are highly relevant to the development and progression of cardiovascular and respiratory disease states. In this review, we described the evidence that the inflammatory process regulates visceral afferent sensitivity and tonicity, affecting the control of the cardiovascular and respiratory system. Some inflammatory mediators like nitric oxide, angiotensin II, endothelin-1, and arginine vasopressin may inhibit baroreceptor afferents and contribute to the baroreflex...
Source: Autonomic Neuroscience - December 17, 2023 Category: Neuroscience Authors: R M Lataro F Brognara R Iturriaga J F R Paton Source Type: research

Inflammation of some visceral sensory systems and autonomic dysfunction in cardiovascular disease
Auton Neurosci. 2023 Dec 7;251:103137. doi: 10.1016/j.autneu.2023.103137. Online ahead of print.ABSTRACTThe sensitization and hypertonicity of visceral afferents are highly relevant to the development and progression of cardiovascular and respiratory disease states. In this review, we described the evidence that the inflammatory process regulates visceral afferent sensitivity and tonicity, affecting the control of the cardiovascular and respiratory system. Some inflammatory mediators like nitric oxide, angiotensin II, endothelin-1, and arginine vasopressin may inhibit baroreceptor afferents and contribute to the baroreflex...
Source: Autonomic Neuroscience - December 17, 2023 Category: Neuroscience Authors: R M Lataro F Brognara R Iturriaga J F R Paton Source Type: research

Inflammation of some visceral sensory systems and autonomic dysfunction in cardiovascular disease
Auton Neurosci. 2023 Dec 7;251:103137. doi: 10.1016/j.autneu.2023.103137. Online ahead of print.ABSTRACTThe sensitization and hypertonicity of visceral afferents are highly relevant to the development and progression of cardiovascular and respiratory disease states. In this review, we described the evidence that the inflammatory process regulates visceral afferent sensitivity and tonicity, affecting the control of the cardiovascular and respiratory system. Some inflammatory mediators like nitric oxide, angiotensin II, endothelin-1, and arginine vasopressin may inhibit baroreceptor afferents and contribute to the baroreflex...
Source: Autonomic Neuroscience - December 17, 2023 Category: Neuroscience Authors: R M Lataro F Brognara R Iturriaga J F R Paton Source Type: research

Inflammation of some visceral sensory systems and autonomic dysfunction in cardiovascular disease
Auton Neurosci. 2023 Dec 7;251:103137. doi: 10.1016/j.autneu.2023.103137. Online ahead of print.ABSTRACTThe sensitization and hypertonicity of visceral afferents are highly relevant to the development and progression of cardiovascular and respiratory disease states. In this review, we described the evidence that the inflammatory process regulates visceral afferent sensitivity and tonicity, affecting the control of the cardiovascular and respiratory system. Some inflammatory mediators like nitric oxide, angiotensin II, endothelin-1, and arginine vasopressin may inhibit baroreceptor afferents and contribute to the baroreflex...
Source: Autonomic Neuroscience - December 17, 2023 Category: Neuroscience Authors: R M Lataro F Brognara R Iturriaga J F R Paton Source Type: research

Inflammation of some visceral sensory systems and autonomic dysfunction in cardiovascular disease
Auton Neurosci. 2023 Dec 7;251:103137. doi: 10.1016/j.autneu.2023.103137. Online ahead of print.ABSTRACTThe sensitization and hypertonicity of visceral afferents are highly relevant to the development and progression of cardiovascular and respiratory disease states. In this review, we described the evidence that the inflammatory process regulates visceral afferent sensitivity and tonicity, affecting the control of the cardiovascular and respiratory system. Some inflammatory mediators like nitric oxide, angiotensin II, endothelin-1, and arginine vasopressin may inhibit baroreceptor afferents and contribute to the baroreflex...
Source: Autonomic Neuroscience - December 17, 2023 Category: Neuroscience Authors: R M Lataro F Brognara R Iturriaga J F R Paton Source Type: research

Inflammation of some visceral sensory systems and autonomic dysfunction in cardiovascular disease
Auton Neurosci. 2023 Dec 7;251:103137. doi: 10.1016/j.autneu.2023.103137. Online ahead of print.ABSTRACTThe sensitization and hypertonicity of visceral afferents are highly relevant to the development and progression of cardiovascular and respiratory disease states. In this review, we described the evidence that the inflammatory process regulates visceral afferent sensitivity and tonicity, affecting the control of the cardiovascular and respiratory system. Some inflammatory mediators like nitric oxide, angiotensin II, endothelin-1, and arginine vasopressin may inhibit baroreceptor afferents and contribute to the baroreflex...
Source: Autonomic Neuroscience - December 17, 2023 Category: Neuroscience Authors: R M Lataro F Brognara R Iturriaga J F R Paton Source Type: research

Inflammation of some visceral sensory systems and autonomic dysfunction in cardiovascular disease
Auton Neurosci. 2023 Dec 7;251:103137. doi: 10.1016/j.autneu.2023.103137. Online ahead of print.ABSTRACTThe sensitization and hypertonicity of visceral afferents are highly relevant to the development and progression of cardiovascular and respiratory disease states. In this review, we described the evidence that the inflammatory process regulates visceral afferent sensitivity and tonicity, affecting the control of the cardiovascular and respiratory system. Some inflammatory mediators like nitric oxide, angiotensin II, endothelin-1, and arginine vasopressin may inhibit baroreceptor afferents and contribute to the baroreflex...
Source: Autonomic Neuroscience - December 17, 2023 Category: Neuroscience Authors: R M Lataro F Brognara R Iturriaga J F R Paton Source Type: research

Inflammation of some visceral sensory systems and autonomic dysfunction in cardiovascular disease
Auton Neurosci. 2023 Dec 7;251:103137. doi: 10.1016/j.autneu.2023.103137. Online ahead of print.ABSTRACTThe sensitization and hypertonicity of visceral afferents are highly relevant to the development and progression of cardiovascular and respiratory disease states. In this review, we described the evidence that the inflammatory process regulates visceral afferent sensitivity and tonicity, affecting the control of the cardiovascular and respiratory system. Some inflammatory mediators like nitric oxide, angiotensin II, endothelin-1, and arginine vasopressin may inhibit baroreceptor afferents and contribute to the baroreflex...
Source: Autonomic Neuroscience - December 17, 2023 Category: Neuroscience Authors: R M Lataro F Brognara R Iturriaga J F R Paton Source Type: research

Inflammation of some visceral sensory systems and autonomic dysfunction in cardiovascular disease
Auton Neurosci. 2023 Dec 7;251:103137. doi: 10.1016/j.autneu.2023.103137. Online ahead of print.ABSTRACTThe sensitization and hypertonicity of visceral afferents are highly relevant to the development and progression of cardiovascular and respiratory disease states. In this review, we described the evidence that the inflammatory process regulates visceral afferent sensitivity and tonicity, affecting the control of the cardiovascular and respiratory system. Some inflammatory mediators like nitric oxide, angiotensin II, endothelin-1, and arginine vasopressin may inhibit baroreceptor afferents and contribute to the baroreflex...
Source: Autonomic Neuroscience - December 17, 2023 Category: Neuroscience Authors: R M Lataro F Brognara R Iturriaga J F R Paton Source Type: research

Inflammation of some visceral sensory systems and autonomic dysfunction in cardiovascular disease
Auton Neurosci. 2023 Dec 7;251:103137. doi: 10.1016/j.autneu.2023.103137. Online ahead of print.ABSTRACTThe sensitization and hypertonicity of visceral afferents are highly relevant to the development and progression of cardiovascular and respiratory disease states. In this review, we described the evidence that the inflammatory process regulates visceral afferent sensitivity and tonicity, affecting the control of the cardiovascular and respiratory system. Some inflammatory mediators like nitric oxide, angiotensin II, endothelin-1, and arginine vasopressin may inhibit baroreceptor afferents and contribute to the baroreflex...
Source: Autonomic Neuroscience - December 17, 2023 Category: Neuroscience Authors: R M Lataro F Brognara R Iturriaga J F R Paton Source Type: research

Inflammation of some visceral sensory systems and autonomic dysfunction in cardiovascular disease
Auton Neurosci. 2023 Dec 7;251:103137. doi: 10.1016/j.autneu.2023.103137. Online ahead of print.ABSTRACTThe sensitization and hypertonicity of visceral afferents are highly relevant to the development and progression of cardiovascular and respiratory disease states. In this review, we described the evidence that the inflammatory process regulates visceral afferent sensitivity and tonicity, affecting the control of the cardiovascular and respiratory system. Some inflammatory mediators like nitric oxide, angiotensin II, endothelin-1, and arginine vasopressin may inhibit baroreceptor afferents and contribute to the baroreflex...
Source: Autonomic Neuroscience - December 17, 2023 Category: Neuroscience Authors: R M Lataro F Brognara R Iturriaga J F R Paton Source Type: research

Inflammation of some visceral sensory systems and autonomic dysfunction in cardiovascular disease
Auton Neurosci. 2023 Dec 7;251:103137. doi: 10.1016/j.autneu.2023.103137. Online ahead of print.ABSTRACTThe sensitization and hypertonicity of visceral afferents are highly relevant to the development and progression of cardiovascular and respiratory disease states. In this review, we described the evidence that the inflammatory process regulates visceral afferent sensitivity and tonicity, affecting the control of the cardiovascular and respiratory system. Some inflammatory mediators like nitric oxide, angiotensin II, endothelin-1, and arginine vasopressin may inhibit baroreceptor afferents and contribute to the baroreflex...
Source: Autonomic Neuroscience - December 17, 2023 Category: Neuroscience Authors: R M Lataro F Brognara R Iturriaga J F R Paton Source Type: research

Sympathetic remodeling and altered angiotensin-converting enzyme 2 localization occur in patients with cardiac disease but are not exacerbated by severe COVID-19
CONCLUSIONS: Heterogeneity of sympathetic innervation, which occurs in cardiac disease and is not increased by severe COVID-19, could contribute to arrhythmogenesis. The dominant localization of ACE2 to pericytes suggests that these cells would be the primary target for potential cardiac infection by SARS-CoV-2. Regional changes in ACE2 staining by myocytes and pericytes could have complex effects on cardiac pathophysiology.PMID:38101169 | DOI:10.1016/j.autneu.2023.103134 (Source: Autonomic Neuroscience)
Source: Autonomic Neuroscience - December 15, 2023 Category: Neuroscience Authors: Creighton L Kellum Logan G Kirkland Tasha K Nelson Seth M Jewett Eric Rytkin Igor R Efimov Donald B Hoover Paul V Benson Brant M Wagener Source Type: research