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Carriage of ESBL-producing Klebsiella pneumoniae and Escherichia coli among children in rural Ghana: a cross-sectional study
ConclusionsThe carriage of ESBL-EC and ESBL-KP among children with and without diarrhoea in the Agogo community with a high prevalence ofblaCTX-M-15 is noteworthy, highlighting the importance of both the population as a possible reservoir. This study reports for the first time the ESBL geneblaCTX-M-28 among the studied populations in Ghana. (Source: Antimicrobial Resistance and Infection Control)
Source: Antimicrobial Resistance and Infection Control - July 3, 2023 Category: Infectious Diseases Source Type: research

The incidence of nosocomial bloodstream infection and urinary tract infection in Australian hospitals before and during the COVID-19 pandemic: an interrupted time series study
ConclusionThese mixed findings reflect the uncertainty of the effect the pandemic has had on HAI ’s. Factors to consider in this analysis include local epidemiology, differences between public and private sector facilities, changes in patient populations and profiles between hospitals, and timing of enhanced IPC interventions. Future studies which factor in these differences may provide furth er insight on the effect of COVID-19 on HAIs. (Source: Antimicrobial Resistance and Infection Control)
Source: Antimicrobial Resistance and Infection Control - July 3, 2023 Category: Infectious Diseases Source Type: research

Core components of infection prevention and control programs at the facility level in Kazakhstan: key challenges and opportunities
ConclusionsExisting IPC programs, infrastructure, IPC staffing, workload and supplies present within hospitals in Kazakhstan allow for implementation of effective IPC. Development and dissemination of IPC guidelines based on the recommended WHO IPC core components, improved IPC training system, and implementation of systematic monitoring of IPC practices will be important first steps towards implementing targeted IPC improvement plans in facilities. (Source: Antimicrobial Resistance and Infection Control)
Source: Antimicrobial Resistance and Infection Control - June 22, 2023 Category: Infectious Diseases Source Type: research

Sanitary installations and wastewater plumbing as reservoir for the long-term circulation and transmission of carbapenemase producing Citrobacter freundii clones in a hospital setting
ConclusionsOur findings suggest long-term circulation and transmission of carbapenemase producingC. freundii clones in hospital sanitary installations despite surveillance, daily cleaning and intermittent disinfection protocols. We propose a role for the wastewater drainage system in the spread within and between rooms and for the sanitary installations in the indirect transmission via bioaerosol plumes. To tackle this problem, a multidisciplinary approach is necessary including careful design and maintenance of the plumbing system. (Source: Antimicrobial Resistance and Infection Control)
Source: Antimicrobial Resistance and Infection Control - June 19, 2023 Category: Infectious Diseases Source Type: research

Knowledge, attitude and practice of infection prevention and control precautions among laboratory staff: a mixed-methods systematic review
ConclusionThere is a gap among KAP related to the implementation of IPC guidelines, which indicates that laboratory staff may be at high risk of acquiring infections in the workplace. These findings suggest that training (including IPC precautions, safety policies, safety equipment and materials, safety activities, initial biohazard handling, ongoing monitoring and potential exposure) of laboratory staff to increase their knowledge about IPC precautions could improve their use of these precautions. (Source: Antimicrobial Resistance and Infection Control)
Source: Antimicrobial Resistance and Infection Control - June 13, 2023 Category: Infectious Diseases Source Type: research

Train-the-Trainers in hand hygiene facilitate the implementation of the WHO hand hygiene multimodal improvement strategy in Japan: evidence for the role of local trainers, adaptation, and sustainability
ConclusionsTTTs were successfully adapted and implemented in Japan, leading to sustained hand hygiene promotion activities by local trainers over three years. Further research is warranted to assess the long-term impact on local hand hygiene promotion in different settings. (Source: Antimicrobial Resistance and Infection Control)
Source: Antimicrobial Resistance and Infection Control - June 9, 2023 Category: Infectious Diseases Source Type: research

Central-line associated bloodstream infections in intensive care units before and after implementation of daily antiseptic bathing with chlorhexidine or octenidine: a post-hoc analysis of a cluster-randomised controlled trial
ConclusionsIn this post-hoc analysis of a cRCT, the application of 2% chlorhexidine-impregnated cloths reduced ICU-attributable CLABSI. This preventive effect of chlorhexidine was restricted to CLABSI caused by gram-positive pathogens (CoNS). In contrast, 0.08% octenidine wash mitts did not reduce CLABSI rates in ICUs.Trial registration Registration number DRKS00010475, registration date August 18, 2016. (Source: Antimicrobial Resistance and Infection Control)
Source: Antimicrobial Resistance and Infection Control - June 3, 2023 Category: Infectious Diseases Source Type: research

Correction: A multi-institutional exploration of emergency medicine physicians ’ attitudes and behaviours on antibiotic use during the COVID-19 pandemic: a mixed-methods study
(Source: Antimicrobial Resistance and Infection Control)
Source: Antimicrobial Resistance and Infection Control - June 1, 2023 Category: Infectious Diseases Source Type: research

APSIC dental infection prevention and control (IPC) guidelines
ConclusionsDental facilities should aim for excellence in infection prevention and control practices as this is part of patient safety. The guidelines that come with a checklist help dental facilities to identify gaps for improvement to reach this goal. (Source: Antimicrobial Resistance and Infection Control)
Source: Antimicrobial Resistance and Infection Control - May 30, 2023 Category: Infectious Diseases Source Type: research

APSIC guide for prevention of catheter associated urinary tract infections (CAUTIs)
ConclusionsHealthcare facilities should aim for excellence in care of patients with urinary catheters. It is recommended that healthcare facilities have a catheter associated urinary tract infection prevention program as part of their Infection Prevention and Control program. (Source: Antimicrobial Resistance and Infection Control)
Source: Antimicrobial Resistance and Infection Control - May 30, 2023 Category: Infectious Diseases Source Type: research

Correction: Impact of tooth brushing on oral bacteriota and health care-associated infections among ventilated COVID-19 patients: an intervention study
(Source: Antimicrobial Resistance and Infection Control)
Source: Antimicrobial Resistance and Infection Control - May 29, 2023 Category: Infectious Diseases Source Type: research

Knowledge, attitudes and behaviour of Egyptians towards antibiotic use in the community: can we do better?
ConclusionsAlthough awareness of antibiotic resistance is rising, some wrong perceptions hold fast. This highlights the need for patient and healthcare-tailored awareness sessions as part of a structured and national public health program directed to the Egyptian population. (Source: Antimicrobial Resistance and Infection Control)
Source: Antimicrobial Resistance and Infection Control - May 24, 2023 Category: Infectious Diseases Source Type: research

Surgical site infection surveillance in German hospitals: a national survey to determine the status quo of digitalization
ConclusionsThe degree to which digital solutions were employed for SSI surveillance differed considerably between surgical departments in Germany. Improving availability and accessibility of information in HIS and meeting interoperability standards will be prerequisites for increasing the amount of data exported directly from HIS to national databases and laying the foundation for automated SSI surveillance on a broad scale. (Source: Antimicrobial Resistance and Infection Control)
Source: Antimicrobial Resistance and Infection Control - May 19, 2023 Category: Infectious Diseases Source Type: research

Appropriate antibiotic use and antimicrobial resistance: knowledge, attitudes and behaviour of medical students and their needs and preferences for learning
ConclusionsOur results show that even medical students who were interested in the AMR problem were not able to use antibiotics appropriately due to gaps in knowledge and a lack of clinical skills. Based on the insights gained in the learning preferences of students and their content priorities, improved student-centred teaching materials should be developed. (Source: Antimicrobial Resistance and Infection Control)
Source: Antimicrobial Resistance and Infection Control - May 17, 2023 Category: Infectious Diseases Source Type: research

Epidemiology of community origin of major multidrug-resistant ESKAPE uropathogens in a paediatric population in South-East Gabon
ConclusionThis study determined the epidemiology ofESKAPE uropathogens in paediatric UTIs. It found a high prevalence of paediatric UTIs associated with children ’s socio-clinical characteristics and diverse bacterial antibiotic resistance phenotypes. (Source: Antimicrobial Resistance and Infection Control)
Source: Antimicrobial Resistance and Infection Control - May 12, 2023 Category: Infectious Diseases Source Type: research