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Staphylococcus aureus surgical site infection rates in 5 European countries
ConclusionsThis large procedure-independent study ofS. aureus SSI proves a low overall infection rate of 0.4% in this cohort. It provides proof of principle for a semi-automated approach to utilize big data in epidemiological studies of healthcare-associated infections.Trials registration The study was registered at clinicaltrials.gov under NCT03353532 (11/2017). (Source: Antimicrobial Resistance and Infection Control)
Source: Antimicrobial Resistance and Infection Control - September 19, 2023 Category: Infectious Diseases Source Type: research

The impact of the COVID-19 pandemic on the treatment of common infections in primary care and the change to antibiotic prescribing in England
ConclusionsChanges to consultations and hospital admissions may be driven by reduced transmission of non-COVID-19 infections due to reduced social mixing and lockdowns. Inconsistencies in coding practice emphasises the need for improvement to inform new antibiotic stewardship policies and prevent resistance to novel infections. (Source: Antimicrobial Resistance and Infection Control)
Source: Antimicrobial Resistance and Infection Control - September 16, 2023 Category: Infectious Diseases Source Type: research

Antibiotic prescribing to inpatients in Limpopo, South Africa: a multicentre point-prevalence survey
ConclusionsThe study serves as a baseline for ABU surveillance at the five regional hospitals in Limpopo Province. Lack of documentation indicates poor prescribing practices; ASP should address gaps by deploying evidence-based, multifaceted and stepwise interventions. (Source: Antimicrobial Resistance and Infection Control)
Source: Antimicrobial Resistance and Infection Control - September 16, 2023 Category: Infectious Diseases Source Type: research

No difference in bacterial contamination of hip capsule sutures and control sutures in hip arthroplasty surgery
ConclusionsThis study showed that around 7% of capsule sutures used in primary THA were contaminated with bacteria and as such exchange by new sutures at the time of capsule closure could be an appealing PJI preventive measure. However, since similar contamination rates were encountered with mainly non-virulent bacteria for both suture groups, the PJI preventive effect of this measure appears to be minimal. (Source: Antimicrobial Resistance and Infection Control)
Source: Antimicrobial Resistance and Infection Control - September 14, 2023 Category: Infectious Diseases Source Type: research

Empiric antimicrobial therapy in the intensive care unit based on the risk of multidrug-resistant bacterial infection: a single-centre case ‒control study of blood culture results in Japan
ConclusionsEven in critically ill patients in the ICU, MDR bacteria are unlikely to be detected in patients without the risk of MDR bacterial infections. Therefore, for such patients, a strategy of starting empiric narrow-spectrum antimicrobial therapy rather than empiric broad-spectrum therapy should be considered. This strategy, in conjunction with daily updates of clinical and epidemiological data at each facility, will promote the appropriate use of antimicrobials and reduce the emergence of MDR bacteria in the ICU.Trial registration: None. (Source: Antimicrobial Resistance and Infection Control)
Source: Antimicrobial Resistance and Infection Control - September 12, 2023 Category: Infectious Diseases Source Type: research

Usefulness of dynamic regression time series models for studying the relationship between antimicrobial consumption and bacterial antimicrobial resistance in hospitals: a systematic review
ConclusionDespite their statistical robustness,  DR models are not widely used. They confirmed the important role of fluoroquinolones, cephalosporins and carbapenems in the emergence of AMR. However, further studies are needed to assess their predictive capacity and usefulness for ASPs. (Source: Antimicrobial Resistance and Infection Control)
Source: Antimicrobial Resistance and Infection Control - September 12, 2023 Category: Infectious Diseases Source Type: research

SARS-CoV-2 risk in household contacts of healthcare workers: a prospective cohort study
ConclusionsSARS-CoV-2 positivity in household contacts of HCW increases with higher cumulative COVID-19 patient exposure of HCWs. Measures reducing the SARS-CoV-2 risk in HCW might indirectly reduce the infection risk of their households. (Source: Antimicrobial Resistance and Infection Control)
Source: Antimicrobial Resistance and Infection Control - September 8, 2023 Category: Infectious Diseases Source Type: research

External validation of semi-automated surveillance algorithms for deep surgical site infections after colorectal surgery in an independent country
ConclusionsThe results highlight the importance of thorough validation before implementation in other clinical settings than in which algorithms were originally developed: the algorithm excluding microbiology cultures had highest sensitivity in this new setting and has the potential to support large-scale semi-automated surveillance of SSI after colorectal surgery. (Source: Antimicrobial Resistance and Infection Control)
Source: Antimicrobial Resistance and Infection Control - September 8, 2023 Category: Infectious Diseases Source Type: research

Review on infection control strategies to minimize outbreaks of the emerging pathogen Elizabethkingia anophelis
ConclusionStrategies to prevent and reduce spread ofE. anophelis include water-free patient rooms, adequate hygiene and disinfection practices, and optimized diagnostic techniques for screening, identification and molecular typing. (Source: Antimicrobial Resistance and Infection Control)
Source: Antimicrobial Resistance and Infection Control - September 8, 2023 Category: Infectious Diseases Source Type: research

Environmental approaches to controlling Clostridioides difficile infection in healthcare settings
AbstractAs today ’s most prevalent and costly healthcare-associated infection, hospital-onsetClostridioides difficile infection (HO-CDI) represents a major threat to patient safety world-wide. This review will discuss how new insights into the epidemiology of CDI have quantified the prevalence ofC. difficile (CD) spore contamination of the patient-zone as well as the role of asymptomatically colonized patients who unavoidable contaminate their near and distant environments with resilient spores. Clarification of the epidemiology of CD in parallel with the development of a new generation of sporicidal agents which can be ...
Source: Antimicrobial Resistance and Infection Control - September 7, 2023 Category: Infectious Diseases Source Type: research

How biofilm changes our understanding of cleaning and disinfection
AbstractBiofilms are ubiquitous in healthcare settings. By nature, biofilms are less susceptible to antimicrobials and are associated with healthcare-associated infections (HAI). Resistance of biofilm to antimicrobials is multifactorial with the presence of a matrix composed of extracellular polymeric substances and eDNA, being a major contributing factor. The usual multispecies composition of environmental biofilms can also impact on antimicrobial efficacy. In healthcare settings, two main types of biofilms are present: hydrated biofilms, for example, in drains and parts of some medical devices and equipment, and environm...
Source: Antimicrobial Resistance and Infection Control - September 7, 2023 Category: Infectious Diseases Source Type: research

Hand hygiene knowledge, attitude, barriers and improvement measures among healthcare workers in the Republic of Korea: a cross-sectional survey exploring interprofessional differences
ConclusionDifferences in knowledge, attitude and barriers hindering HH compliance and improvement plans were identified for each group. The findings suggest that targeted interventions tailored to the specific needs of different occupational groups may effectively improve HH compliance in healthcare settings. (Source: Antimicrobial Resistance and Infection Control)
Source: Antimicrobial Resistance and Infection Control - September 7, 2023 Category: Infectious Diseases Source Type: research

Does repeated exposure to hydrogen peroxide induce Candida auris resistance?
ConclusionsThe adoption of H2O2 solutions in routine protocols in order to promote disinfection standards againstCandida auris, improving patient safety and reducing healthcare costs, is certainly welcomed. (Source: Antimicrobial Resistance and Infection Control)
Source: Antimicrobial Resistance and Infection Control - September 7, 2023 Category: Infectious Diseases Source Type: research

First report of Candida auris in Romania: clinical and molecular aspects
AbstractThe emerging opportunistic fungal pathogenCandida auris raises significant concerns for public health due to its outbreak potential, the associated high mortality, increased resistance to antifungals, challenging identification to species level, since commonly used diagnostic methods can confuse this fungus with otherCandida spp. The present outbreak report describes probably some of the firstCandida auris cases in Romania, providing clinical and epidemiological data, and also whole genome sequencing data. The cases were identified in three hospitals in Bucharest during the first eight months of 2022. (Source: Anti...
Source: Antimicrobial Resistance and Infection Control - September 7, 2023 Category: Infectious Diseases Source Type: research

International Conference on Prevention and Infection Control 2023
(Source: Antimicrobial Resistance and Infection Control)
Source: Antimicrobial Resistance and Infection Control - September 5, 2023 Category: Infectious Diseases Source Type: research