Exploring the use of cluster analysis to assess antibiotic stewardship in critically-ill neonates in a low resource setting
ConclusionsThe first antibiotic line failed in one out of four newborns with probable sepsis while third-generation cephalosporins were insufficient in one in ten patients. Cluster analysis can provide valuable insights into antibiotic treatment patterns and their potential implications. This approach may support antibiotic stewardship and aid in contrasting antimicrobial resistance in limited resource settings. (Source: Antimicrobial Resistance and Infection Control)
Source: Antimicrobial Resistance and Infection Control - October 31, 2023 Category: Infectious Diseases Source Type: research

The ICU-CARB score: a novel clinical scoring system to predict carbapenem-resistant gram-negative bacteria carriage in critically ill patients upon ICU admission
ConclusionsThe ICU-CARB Score serves as a straightforward and precise tool that enables prompt evaluation of the risk of CR-GNB carriage at the time of ICU admission, thereby facilitating the timely implementation of targeted pre-emptive isolation. (Source: Antimicrobial Resistance and Infection Control)
Source: Antimicrobial Resistance and Infection Control - October 28, 2023 Category: Infectious Diseases Source Type: research

The augmented value of using clinical notes in semi-automated surveillance of deep surgical site infections after colorectal surgery
ConclusionsThe addition of an NLP component to the existing algorithm had modest effect on WR (decrease of 1.4 –12.5%), at the cost of sensitivity. For future implementation it will be a trade-off between optimal case-finding techniques versus practical considerations such as acceptability and availability of resources. (Source: Antimicrobial Resistance and Infection Control)
Source: Antimicrobial Resistance and Infection Control - October 26, 2023 Category: Infectious Diseases Source Type: research

Activity of antimicrobial examination gloves under realistic conditions: challenge not fulfilled
ConclusionThe lack of activity of the active principle against Gram-negative microorganisms could be confirmed. The reduction factors of>  4 log10 within 5  min for Gram-positive microorganisms claimed for the product using a standard test procedure (ASTM D7907) could not be confirmed in a realistic experimental test set-up even after 10 min of light exposure. The effectiveness against Gram-positive microorganisms should be further investigated under realistic (dry) conditions, including patient care. At this stage, the use of supposedly antimicrobial gloves should not be recommended, as the belief in their efficacy...
Source: Antimicrobial Resistance and Infection Control - October 24, 2023 Category: Infectious Diseases Source Type: research

Spatial clusters of extended-spectrum beta-lactamase-producing Escherichia coli causing community-onset bacteriuria due to repeat infections: cluster analysis from a large urban medical center, San Francisco, 2014 –2020
ConclusionWe found spatial clusters of ESBL-E. coli bacteriuria episodes. However, this was partly explained by clustering within individuals more than between individuals, as having an ESBL-E. coli bacteriuria was associated with recurrence with ESBL-E. coli. These findings may help better tailor clinical treatment of patients with recurrent urinary tract infections after an initial episode caused by ESBL-E. coli. (Source: Antimicrobial Resistance and Infection Control)
Source: Antimicrobial Resistance and Infection Control - October 20, 2023 Category: Infectious Diseases Source Type: research

Developing a framework for regular and sustainable qualitative assessment of antibiotic use in Korean medical institutions: a Delphi study
ConclusionThis study provides a framework for establishing a qualitative assessment of antimicrobial use for medical institutions at a national level in the Republic of Korea. (Source: Antimicrobial Resistance and Infection Control)
Source: Antimicrobial Resistance and Infection Control - October 18, 2023 Category: Infectious Diseases Source Type: research

Effective infection prevention and control measures in long-term care facilities in non-outbreak and outbreak settings: a systematic literature review
ConclusionIn the non-outbreak setting in LTCF, especially hand hygiene and oral hygiene have a beneficial effect on infection rates. In contrast, IPC bundles, as well as mass testing seem to be promising in an outbreak setting. (Source: Antimicrobial Resistance and Infection Control)
Source: Antimicrobial Resistance and Infection Control - October 18, 2023 Category: Infectious Diseases Source Type: research

Antibiotic use at a tertiary hospital in Tanzania: findings from a point prevalence survey
ConclusionThe findings of a high prevalence of antibiotic use, inadequate use of bacterial culture, and frequent empiric antibiotic treatment suggests the need for strengthening diagnostic and antimicrobial stewardship programs. Furthermore, this study has identified areas for quality improvement, including education programs focusing on prescription practice. (Source: Antimicrobial Resistance and Infection Control)
Source: Antimicrobial Resistance and Infection Control - October 10, 2023 Category: Infectious Diseases Source Type: research

Clean Hospitals Day 2023 marks the global launch of a self-assessment tool
(Source: Antimicrobial Resistance and Infection Control)
Source: Antimicrobial Resistance and Infection Control - October 8, 2023 Category: Infectious Diseases Source Type: research

Antiseptics and mupirocin resistance in clinical, environmental, and colonizing coagulase negative Staphylococcus isolates
ConclusionsCoNS isolates colonizing healthcare workers showed a high prevalence of antiseptic resistance genes, while clinical infection samples were more resistant to antibiotics. CHDG demonstrated greater efficacy than BC and CTAB in our hospital. (Source: Antimicrobial Resistance and Infection Control)
Source: Antimicrobial Resistance and Infection Control - October 4, 2023 Category: Infectious Diseases Source Type: research

Correction: Factors associated with hand washing effectiveness: an institution-based observational study
(Source: Antimicrobial Resistance and Infection Control)
Source: Antimicrobial Resistance and Infection Control - September 29, 2023 Category: Infectious Diseases Source Type: research

Correction: Infection prevention knowledge, practice, and its associated factors among healthcare providers in primary healthcare unit of Wogdie District, Northeast Ethiopia, 2019: a cross-sectional study
(Source: Antimicrobial Resistance and Infection Control)
Source: Antimicrobial Resistance and Infection Control - September 29, 2023 Category: Infectious Diseases Source Type: research

Correction: A systematic literature review of economic evaluation studies of interventions impacting antimicrobial resistance
(Source: Antimicrobial Resistance and Infection Control)
Source: Antimicrobial Resistance and Infection Control - September 29, 2023 Category: Infectious Diseases Source Type: research

Association between perioperative prophylaxis with cefuroxime plus metronidazole or amoxicillin/clavulanic acid and surgical site infections in paediatric uncomplicated appendectomy: a Swiss retrospective cohort study
ConclusionWe found lower odds of post-appendectomy SSI in children receiving cefuroxime plus metronidazole compared to amoxicillin/clavulanic acid. Treating amoxicillin/clavulanic acid as the baseline, only 55 children need to receive cefuroxime plus metronidazole perioperative prophylaxis to avert one SSI. Existing guidelines recommending amoxicillin/clavulanic acid may need to be revised.Trial registration ISRCTN47727811, registered retrospectively. (Source: Antimicrobial Resistance and Infection Control)
Source: Antimicrobial Resistance and Infection Control - September 25, 2023 Category: Infectious Diseases Source Type: research

Association of antimicrobial perioperative prophylaxis with cefuroxime plus metronidazole or amoxicillin/clavulanic acid and surgical site infections in colorectal surgery
ConclusionsDespite its activity against enterococci, A/CA was less effective than C  + M for preventing SSI, suggesting that it should not be a first choice antibiotic prophylaxis for colorectal surgery. (Source: Antimicrobial Resistance and Infection Control)
Source: Antimicrobial Resistance and Infection Control - September 19, 2023 Category: Infectious Diseases Source Type: research