Steroids in infantile spasms syndrome: Another trial, another drug, another dose, what & #39;s next ?
Robyn Whitney, Puneet JainAnnals of Indian Academy of Neurology 2022 25(5):799-800 (Source: Annals of Indian Academy of Neurology)
Source: Annals of Indian Academy of Neurology - October 31, 2022 Category: Neurology Authors: Robyn Whitney Puneet Jain Source Type: research

Diagnosing subtypes of progressive supranuclear palsy: Can 18F-FDG PET/CT imaging guide our way ?
Ishita Desai, Niraj KumarAnnals of Indian Academy of Neurology 2022 25(5):796-798 (Source: Annals of Indian Academy of Neurology)
Source: Annals of Indian Academy of Neurology - October 31, 2022 Category: Neurology Authors: Ishita Desai Niraj Kumar Source Type: research

Is tenecteplase a viable alternative to alteplase in the treatment of acute ischemic stroke ?
Anand Girish VaishnavAnnals of Indian Academy of Neurology 2022 25(5):794-795 (Source: Annals of Indian Academy of Neurology)
Source: Annals of Indian Academy of Neurology - October 31, 2022 Category: Neurology Authors: Anand Girish Vaishnav Source Type: research

Trail toward tenecteplase
Trilochan Srivastava, Neetu Ramrakhiani, Vikram BohraAnnals of Indian Academy of Neurology 2022 25(5):792-793 (Source: Annals of Indian Academy of Neurology)
Source: Annals of Indian Academy of Neurology - October 31, 2022 Category: Neurology Authors: Trilochan Srivastava Neetu Ramrakhiani Vikram Bohra Source Type: research

Movement disorders in demyelinating disorders: How important is this historical link today ?
Salil GuptaAnnals of Indian Academy of Neurology 2022 25(5):790-791 (Source: Annals of Indian Academy of Neurology)
Source: Annals of Indian Academy of Neurology - October 31, 2022 Category: Neurology Authors: Salil Gupta Source Type: research

Deciphering the footprints of autoimmunity in CNS demyelinating disorders
M NetravathiAnnals of Indian Academy of Neurology 2022 25(5):787-789 (Source: Annals of Indian Academy of Neurology)
Source: Annals of Indian Academy of Neurology - October 31, 2022 Category: Neurology Authors: M Netravathi Source Type: research

ABC of gaze and ocular oscillations
Mohan MadhusudananAnnals of Indian Academy of Neurology 2022 25(8):113-119 The chief goal of all eye movements is to maintain the image of an object steady on the retina especially the macula to preserve visual acuity. Gaze palsy refers to lack of the conjugate movements due to a failure of supranuclear control mechanisms. Supranuclear control is maintained by not one, but multiple eye movement systems and gaze mechanisms. Supranuclear gaze palsies can be associated with a myriad of aetiologies- from trauma or metabolic abnormalities to stroke, demyelinating disorders and space occupying lesions like tumours. Culprit lesi...
Source: Annals of Indian Academy of Neurology - October 19, 2022 Category: Neurology Authors: Mohan Madhusudanan Source Type: research

Cerebral visual loss
Jason J S. BartonAnnals of Indian Academy of Neurology 2022 25(8):106-112 Cerebral visual disorders include a range of common and rare deficits. They can be divided into effects on low-, intermediate-, and high-level forms of visual processing. Low-level deficits are various forms of homonymous hemifield scotomata, which affect all types of vision within their borders. Intermediate-level deficits refer to impairments of colour or motion perception, which affect either one hemifield or the entire field when lesions are bilateral. High-level deficits are divided into those of the ventral (occipitotemporal) or dorsal (occipi...
Source: Annals of Indian Academy of Neurology - October 19, 2022 Category: Neurology Authors: Jason J S. Barton Source Type: research

Paraneoplastic syndromes in neuro-ophthalmology
This article will discuss these conditions, their management and prognosis. (Source: Annals of Indian Academy of Neurology)
Source: Annals of Indian Academy of Neurology - October 19, 2022 Category: Neurology Authors: Simon J Hickman Source Type: research

Eye signs in stroke
Rajeshwar Sahonta, Ivy Sebastian, Sanjit Aaron, Appaswamy T Prabakhar, Anupriya Arthur, Jeyaraj D PandianAnnals of Indian Academy of Neurology 2022 25(8):94-100 A large part of the central nervous system is involved in the normal functioning of the vision, and hence vision can be affected in a stroke patient. Transient visual symptoms can likewise be a harbinger of stroke and prompt rapid evaluation for the prevention of recurrent stroke. A carotid artery disease can manifest as transient monocular visual loss (TMVL), central retinal artery occlusion (CRAO), anterior ischemic optic neuropathy or ocular ischemic syndrome (...
Source: Annals of Indian Academy of Neurology - October 19, 2022 Category: Neurology Authors: Rajeshwar Sahonta Ivy Sebastian Sanjit Aaron Appaswamy T Prabakhar Anupriya Arthur Jeyaraj D Pandian Source Type: research

Clinical signs in neuro-ophthalmology: Eye signs in myasthenia gravis
Sui Hsien WongAnnals of Indian Academy of Neurology 2022 25(8):91-93 A hallmark of myasthenia gravis (MG) is the variability and fatigability of striated muscles. The majority of people with MG have eye symptoms of ptosis and diplopia. This paper outlines the eye signs in MG, including practical tips on the examination technique relevant to MG, and pitfalls to avoid. (Source: Annals of Indian Academy of Neurology)
Source: Annals of Indian Academy of Neurology - October 19, 2022 Category: Neurology Authors: Sui Hsien Wong Source Type: research

Tolosa & #8211;Hunt Syndrome and IgG4 diseases in Neuro-Ophthalmology
Aastha Takkar Kapila, Sucharita Ray, Vivek LalAnnals of Indian Academy of Neurology 2022 25(8):83-90 Tolosa–Hunt syndrome (THS) remains a challenging diagnosis for many neurologists. Often believed to be a rare presentation, the classical presentation is known to involve cranial nerves and tissues surrounding the cavernous sinus. Traditionally, a diagnosis of THS is considered when all secondary conditions have been ruled out. Yet, newer findings have elaborated a complex pathogenetic process with some overlap from the IgG4 spectrum of disorders, with which it shares many phenotypic similarities. In this narr...
Source: Annals of Indian Academy of Neurology - October 19, 2022 Category: Neurology Authors: Aastha Takkar Kapila Sucharita Ray Vivek Lal Source Type: research

Oculomotor cranial neuropathies: Diagnosis and management
Ritu Shree, Karthik Vinay Mahesh, Neeraj Balaini, Abeer GoelAnnals of Indian Academy of Neurology 2022 25(8):70-82 Ocular nerve palsies are among the most common cranial neuropathies in neurological practice. Nerves can get affected anywhere along their path from the brainstem to the orbit. There can be isolated involvement of multiple cranial nerves together. The etiologies differ according to the type of presentation. The steps toward the diagnosis need to be strategically planned and must be based on clinical localization. It is crucial to make proper localization to plan further investigations and thus treatment of th...
Source: Annals of Indian Academy of Neurology - October 19, 2022 Category: Neurology Authors: Ritu Shree Karthik Vinay Mahesh Neeraj Balaini Abeer Goel Source Type: research

Clinical profile of patients with leber hereditary optic neuropathy (LHON): An ambispective study of North Indian Cohorts
Discussion: Clinical profile of 83 patients with both positive and negative mutations was analyzed. Twenty-three out of 161 patients (14.3%) tested positive for either of the three mutations. The majority of the patients harbored G11778A mutation (56.52%) followed by T14484C (34.78%) and G3460A (8.69%). No statistical difference could be noted between the clinical profiles of mutation-negative and -positive patients. (Source: Annals of Indian Academy of Neurology)
Source: Annals of Indian Academy of Neurology - October 19, 2022 Category: Neurology Authors: Vinny Wilson Prabhjit Kaur Sofia Singh Radhika P Ramachandran Vislavath Jyothi Karthik V Mahesh Aastha Takkar Giriraj Chandak Ramandeep Singh Source Type: research

Idiopathic intracranial hypertension from benign to fulminant: Diagnostic and management issues
Meagan D Seay, Kathleen B DigreAnnals of Indian Academy of Neurology 2022 25(8):59-64 Idiopathic intracranial hypertension (IIH) primarrily affects obese women of childbearing years and is commonly associated with headaches, pulsatile tinnitus, and vision changes. Though most patients have a “benign” course, it can lead to significant morbidity, including blindness. The treatment approach is based on severity of visual impact and includes weight loss, intracranial pressure lowering medications, and sometimes surgery, such as spinal fluid diversion, optic nerve sheath fenestration, or venous sinus...
Source: Annals of Indian Academy of Neurology - October 19, 2022 Category: Neurology Authors: Meagan D Seay Kathleen B Digre Source Type: research