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Comparing bridging thrombolysis with direct thrombectomy in stroke due to large vessel occlusion- Indian Experience (LVO-Direct)
Conclusion: Direct thrombectomy has comparable outcomes to bridging thrombolysis in emergent large vessel occlusions. (Source: Annals of Indian Academy of Neurology)
Source: Annals of Indian Academy of Neurology - October 31, 2022 Category: Neurology Authors: Chintan Prajapati Vikram Huded Niranjan Mahajan Anirudh Kulkarni Delitia Manual Source Type: research

Comparison of neurological manifestations in the two waves of COVID-19 Infection: A cross-sectional study
Conclusion: Meningoencephalitis, headache, and seizures were found to be more common in second wave as compared to first wave. The severity and mortality rate were higher in the second wave. (Source: Annals of Indian Academy of Neurology)
Source: Annals of Indian Academy of Neurology - October 31, 2022 Category: Neurology Authors: Sachin Sureshbabu Merisin Joseph CV Haseena Noufal Basheer RN Srutha Keerthi N Samrooda KP Abdurehiman PV Deepthi Babitha Peter Jacob Alappat Source Type: research

Sleep architecture in progressive supranuclear palsy: A video-polysomnography study
Conclusions: Sleep architecture is altered in PSP even during the early stages of the disease. There is reduced total sleep including both non-REM and REM sleep, sleep efficiency, prolonged sleep latencies, and increased wake duration. This correlates with the neurodegenerative processes affecting the anatomical region regulating the sleep/wake cycle like dorsal raphe nucleus, locus coeruleus (LC), pedunculopontine nucleus (PPN). (Source: Annals of Indian Academy of Neurology)
Source: Annals of Indian Academy of Neurology - October 31, 2022 Category: Neurology Authors: Srikanth Yadav Boini Rohan Mahale Seshagiri Donaparthi Nitish Kamble Vikram V Holla Pramod Kumar Pal Bindu Kutty Ravi Yadav Source Type: research

Retinal degeneration in patients with Wilson & #39;s disease: An OCT study in Asian Indian Population
Conclusions: Abnormalities of the retinal layers were observed in the patients with WD. OCT is a non-invasive tool to identify and quantify the abnormalities of the retinal layers. (Source: Annals of Indian Academy of Neurology)
Source: Annals of Indian Academy of Neurology - October 31, 2022 Category: Neurology Authors: Amitabh Bhattacharya Albert Stezin Nitish Kamble PM Mohammed Shereef Bakula Kashyap Pramod Kumar Pal Source Type: research

P-tau231 as a diagnostic biomarker for Alzheimer & #39;s Disease and mild cognitive impairment: A systematic review and meta-analysis
Conclusion: P-tau231 showed to be a valuable biomarker of discrimination AD, MCI, and NC based on our findings. This meta-analysis showed that the CSF p-tau231 can reliably differentiate AD patients from MCI and NC patients. Furthermore, based on our findings the level of CSF p-tau231 was significantly higher in MCI compared to NC. Therefore, p-tau231 can be added to the list of potential biomarkers for the diagnosis of AD and MCI in further studies. However, further investigations are needed to confirm our findings. (Source: Annals of Indian Academy of Neurology)
Source: Annals of Indian Academy of Neurology - October 31, 2022 Category: Neurology Authors: Fardin Nabizadeh Negin Salehi Elham Ramezannezhad Shaghayegh Sadeghmousavi Elham Khalili Source Type: research

Diabetic amyotrophy (Bruns-Garland syndrome): A narrative review
Conclusion: The prognosis is good as most patients improve to near- normal strength with pain cessation within 18 months of onset. (Source: Annals of Indian Academy of Neurology)
Source: Annals of Indian Academy of Neurology - October 31, 2022 Category: Neurology Authors: Ayush Agarwal MV Padma Srivastava Venugopalan Y Vishnu Source Type: research

COVID-19 and dementia; Hard to forget yet haunting forgetfulness!
Ariyanachi Kaliappan, Archana Gaur, Varatharajan Sakthivadivel, Yuvaraj Balan, Lakshmi Jyothi Tadi, Raja SundaramurthyAnnals of Indian Academy of Neurology 2022 25(5):832-840 The current pandemic has affected almost everyone worldwide. Although the majority of people survive the illness, bad cognitive repercussions might last a long time, resulting in a lower quality of life and disability, particularly in severe cases. We tried to understand and bring together the various possible mechanisms leading to dementia in COVID-19. The link between COVID-19 and dementia will help public health workers plan and allocate resources...
Source: Annals of Indian Academy of Neurology - October 31, 2022 Category: Neurology Authors: Ariyanachi Kaliappan Archana Gaur Varatharajan Sakthivadivel Yuvaraj Balan Lakshmi Jyothi Tadi Raja Sundaramurthy Source Type: research

Movement disorder in demyelinating disease: Tracing the Charcot & #39;s foot print
Rashmi Singh, Sanjay PandeyAnnals of Indian Academy of Neurology 2022 25(5):821-831 Movement disorders may be one of the neurological manifestations of demyelinating disorders. They can manifest in Parkinsonism or a wide spectrum of hyperkinetic movement disorders including tremor, paroxysmal dyskinesia, dystonia, chorea, and ballism. Some of these disorders occur during an acute episode of demyelination, whereas others can develop later or even may precede the onset of the demyelinating disorders. The pathophysiology of movement disorders in demyelination is complex and the current evidence indicates a wide involvement o...
Source: Annals of Indian Academy of Neurology - October 31, 2022 Category: Neurology Authors: Rashmi Singh Sanjay Pandey Source Type: research

Parkinson & #39;s disease and wearable technology: An Indian perspective
Vaishali Bagrodia, Vikram V Holla, Nitish L Kamble, Pramod K Pal, Ravi YadavAnnals of Indian Academy of Neurology 2022 25(5):817-820 Parkinson's disease (PD) is the second most prevalent neurodegenerative disorder. In India, an accurate number of PD patients remains uncertain owing to the unawareness of PD symptoms in the geriatric population and the large discrepancy between the number of PD patients and trained neurologists. Constructing additional neurological care centers along with using technology and integrating it into digital healthcare platforms will help reduce this burden. Use of technology in PD di...
Source: Annals of Indian Academy of Neurology - October 31, 2022 Category: Neurology Authors: Vaishali Bagrodia Vikram V Holla Nitish L Kamble Pramod K Pal Ravi Yadav Source Type: research

Management of Parkinson & #39;s disease dysarthria: Can artificial intelligence provide the solution ?
Raj Kumar, Manoj Tripathy, Niraj Kumar, Radhey Shyam AnandAnnals of Indian Academy of Neurology 2022 25(5):810-816 Speech disorder is a significant problem for people affected with Parkinson's disease (PD) leading to a substantial disability to communicate with others. PD affects the voice, including changes in pitch, intensity, articulation, and syllable rate.We aimed to study the current status of artificial intelligence (AI) using machine learning algorithms (MLAs) in the assessment of speech abnormalities in PD along with the generation of intelligible synthetic speech for voice rehabilitation. We searched ...
Source: Annals of Indian Academy of Neurology - October 31, 2022 Category: Neurology Authors: Raj Kumar Manoj Tripathy Niraj Kumar Radhey Shyam Anand Source Type: research

Finding the best: Corticosteroids for the treatment of west syndrome
Lakshminarayanan Kannan, Lokesh SainiAnnals of Indian Academy of Neurology 2022 25(5):808-809 (Source: Annals of Indian Academy of Neurology)
Source: Annals of Indian Academy of Neurology - October 31, 2022 Category: Neurology Authors: Lakshminarayanan Kannan Lokesh Saini Source Type: research

Oral prednisolone versus dexamethasone for the treatment of infantile epileptic spasms syndrome: Current status and way forward
Jitendra Kumar Sahu, Sandeep NegiAnnals of Indian Academy of Neurology 2022 25(5):807-807 (Source: Annals of Indian Academy of Neurology)
Source: Annals of Indian Academy of Neurology - October 31, 2022 Category: Neurology Authors: Jitendra Kumar Sahu Sandeep Negi Source Type: research

Cardiovascular autonomic dysfunction in Parkinson & #39;s disease: Editorial commentary
Kamalesh Chakravarty, Sucharita RayAnnals of Indian Academy of Neurology 2022 25(5):805-806 (Source: Annals of Indian Academy of Neurology)
Source: Annals of Indian Academy of Neurology - October 31, 2022 Category: Neurology Authors: Kamalesh Chakravarty Sucharita Ray Source Type: research

Cardiovascular autonomic dysfunction in idiopathic Parkinson & #39;s disease
Sahil MehtaAnnals of Indian Academy of Neurology 2022 25(5):803-804 (Source: Annals of Indian Academy of Neurology)
Source: Annals of Indian Academy of Neurology - October 31, 2022 Category: Neurology Authors: Sahil Mehta Source Type: research

Movement disorder emergencies: When & #8220;Too Much & #8221; or & #8220;Too Little & #8221; movement needs urgent attention!!
Ishita Desai, Niraj KumarAnnals of Indian Academy of Neurology 2022 25(5):801-802 (Source: Annals of Indian Academy of Neurology)
Source: Annals of Indian Academy of Neurology - October 31, 2022 Category: Neurology Authors: Ishita Desai Niraj Kumar Source Type: research